A drug called oxcarbazepine that is safe and effective enough to be used alone in patients with partial epilepsy who do not respond to other anti-epileptic drugs is demonstrated by a study led by a University of Michigan neurologist (Neurology, 6-00).
Heart surgery patients who suffer severe problems after stents are inserted into their unclogged arteries are among those with medical implants who may benefit from a general anti-inflammatory surface treatment for biomedical materials, reported for the first time in the Journal of Biomedical Materials Research.
Genetics researchers are teasing out details of how chromosome 22's unstable chemical structure renders it vulnerable to breaks and rearrangements, resulting in genetic disease (Human Molecular Genetics, 7-00).
Eating less may be good for the health of your brain, and may help keep debilitating ailments such as Alzheimer's and Parkinson's diseases at bay. That is the message from a study that employed a gene-scanning technique to analyze activity in thousands of genes in mice (Nature Genetics, 7-00).
A newly developed microcamera, which can be swallowed as a pill, provides wireless images of the inside of the intestine.
Engineer J. Robert Ashley considers the controversial subject of magnetic and electric fields generated by high-voltage transmission lines.
Sophisticated computer simulators that mimic the look and feel of operating room procedures are now making inroads into medical education.
In what seems at first an obvious conclusion, researchers at Johns Hopkins and The National Institute on Drug Abuse have found that people who "do" both cocaine and alcohol risk a worse loss of brain function than those who frequently use either drug alone (Neurology, 6-26-00).
The blood vessels of older athletes behave like those of people half their age, according to a new study in Circulation: Journal of the American Heart Association.
The majority of people with cluster headaches may also have sleep disorders that trigger the attacks, according to a study in the June 27 Neurology.
Guidelines to help determine whether people with Alzheimer's disease should continue driving have been issued by AAN (Neurology, 6-27-00).
Researchers have shown for the first time that the human liver can regenerate its tissue with a cell type from outside the organ -- and they present the first compelling evidence that those stem cells are human bone marrow (HEPATOLOGY, 7-00).
In a finding that opens a new avenue to treating liver disease and blood-clotting disorders, researchers have found that the bone marrow is the source of cells that are responsible for the liver's famous ability to regenerate itself (Hepatology, 7-00).
The first study of brain activity associated with pain in patients with knee osteoarthritis -- a degenerative disease of the soft and bony tissues of the knee -- is being conducted by UAB researchers.
Millennium Pharmaceuticals, Inc. and Aventis Pharma signed agreements covering the joint development and commercialization of inflammatory disease drugs; joint development of new drug discovery technologies; transfer of elements of Millennium's technology to Aventis; and purchase of an equity interest in Millennium by Aventis.
A report by AHRQ answers key questions about American hospital care such as who uses hospitals; for what reasons; who pays for what; and what happens to hospital patients. It also provides statistics on the leading reasons for hospital admission, and patients who leave against medical advice.
Michael S. Benninger, Chairman of the Department of Otolaryngology--Head and Neck Surgery at the Henry Ford Hospital in Detroit, is the new Editor in Chief of the jounal Otolaryngology--Head and Neck Surgery.
A national study is under way to test the effectiveness of a vaccine to prevent herpes zoster, or shingles, in older people.
UAB has received a three-year, $805,000 grant from the Agency for Health Care Research and Quality to establish one of seven national Centers for Education and Research on Therapeutics of musculoskeletal disorders such as arthritis and osteoporosis.
Amino acid supplements may provide a cost-effective and safe method for improving the nutritional intake of some dialysis patients who are unable to meet their daily protein requirements, a Johns Hopkins study shows (Kidney International, 6-00).
Boosting production of growth hormone can reduce body fat and help maintain levels of functioning in elderly men and women; however, these potential benefits may be undercut by estrogen replacement therapy.
Honey may be an ideal complement to protein supplements in promoting muscle recuperation and glycogen restoration after training.
A group of more than 75 hospitals across the nation has made substantial progress in improving stoke treatment, already acting on many of the recommendations of the Brain Attack Coalition published in JAMA.
Withdrawal from cocaine is no picnic, but a study by a researcher at the University at Buffalo has shown that it may not involve the wrenching ups and downs and intense cravings that specialists in the field have considered the norm (Drug and Alcohol Dependence, 6-00).
Observational studies published in reputable medical journals often give similar results to randomized controlled trials, according to University of Iowa researchers (NEJM, 6-22-00).
A from-the-heart song, "It's a Good Thing You're Here," is a musical reminder for women to lower their risks for breast cancer with a mammogram; the compact disc features voices of breast cancer survivors, their children and husbands.
A combination of plant chemicals collectively known as phytochemicals in the flesh of apples, and particularly in the skin, provide the fruit's anti-oxidant and anti-cancer benefits, say Cornell food scientists (Nature, 6-22-00).
Healing a human brain from the inside out was supposed to be impossible. Now comes the discovery from a Children's Hospital research group, published in Nature (6-22-00), that our brain's nerve cells or neurons could one day be induced into healing themselves.
The acute insulin response diagnostic test, performed in newborns, allows physicians to identify a rare, severe imbalance of insulin levels that can be cured with organ-sparing surgery.
The Robert Wood Johnson Foundation recently awarded the UIC School of Public Health $347,000 to increase the number of African-Americans and Latinos enrolling and graduating with advanced degrees in the public health sciences.
People who believe they suffer from migraine headaches must be their own advocates in seeking pain relief. Those who have regular headaches should follow 10 steps to the best care, suggest migraine guidelines being announced at the 42nd Annual Scientific Meeting of the American Headache Society.
Separating the wheat from the chaff, a headache specialist has ranked the top 10 migraine consumer Web sites and will announce his list at the 42nd Annual Scientific Meeting of the American Headache Society.
Adolescents prone to migraine are most likely to get the excruciating headaches on Mondays and least likely on Saturdays, according to a large multi-center study being presented at the 42nd Annual Scientific Meeting of the American Headache Society.
Daily narcotic pain medications may not help most people with persistent difficult-to-treat headaches, suggests a prospective 5-year study being presented at the 42nd Annual Scientific Meeting of the American Headache Society.
Use of blood from the umbilical cord reduces the incidence of a potentially life-threatening transplant complication in the first study to directly compare such transplants with bone marrow transplants in children with leukemia and other life-threatening diseases (NEJM, 6-22-00).
Radiologists should clearly state in their mission statements that "productivity is a far less important factor in the determination of income (of radiologists) than...optimal care," says a well-known expert in radiology malpractice issues (American Journal of Roentgenology, 7-00).
Researchers supported by the National Science Foundation have developed a means to detect nitric oxide that could help improve scientists' understanding of this molecule's role in neurological signaling and other biological functions.
One hundred and three medicines are in the pipeline to help the more than 50 million Americans who suffer from some form of mental illness, according to a newly released survey by the Pharmaceutical Research and Manufacturers of America (PhRMA).
Melanoma researchers at UCSD have developed a new drug-combination therapy that has proven in Phase II clinical trials to be significantly better at extending patients' lives than any other drug therapy.
HIV, the virus that causes AIDS, may be adapted for use in gene therapy to treat genetic diseases and disorders of the immune system, even including AIDS, according to a scientist at the University of North Carolina at Chapel Hill.
Women with advanced breast cancer who have abnormal daytime levels of cortisol, a hormone released in response to stress, are significantly more likely to die sooner than patients with normal levels of the hormone, Stanford researchers report in a newly published study.
Mere memory of drug use can alter an area of the brain -- the prefrontal cortex -- not traditionally implicated in addiction, say University of Wisconsin psychiatry researchers (Synapse, 8-00).
"Making Weight: Men's Conflicts with Food, Weight, Shape and Appearance" aims to help men understand that fat is no longer only a feminist issue. The book's co-writers are a leading expert on male eating disorders, an author of many eating disorder books, and a psychiatrist who is recovered from both compulsive exercise and an eating disorder.
AEGON has committed $2 million to Johns Hopkins for prostate and breast cancer research. The Oncology Center will split the funds with the Free University Oncology Research Institute in Amsterdam for a collaborative research project.
More than 7,500 pharmaceutical scientists will gather in Indianapolis, October 29-November 2, at the 2000 AAPS Annual Meeting and Exposition to explore Unmet Medical Needs: Therapies for the New Millennium.
In the first study of its kind in families, researchers have shown that elevated triglycerides -- a blood fat -- sharply increase a person's risk of dying from a heart attack, even if a person's blood cholesterol is normal (Circulation, 6-19-00).
Stanford and Packard hospitals are dismayed that while the nurses' union was still at the bargaining table Friday, union spokespeople were informing the media that talks had collapsed.
An abnormality in a protein that helps clear fat from the blood may explain the greatly increased risk of heart disease that people with diabetes face, according to research published by Columbia University College of Physicians & Surgeons colleagues in the Journal of Clinical Investigation (6-00).
Only 71 to 90 percent of 2-year-olds in the U.S. are fully immunized, and according to a study just released by the Institute of Medicine Committee, that number is too low; only 73 percent of children in Texas are fully immunized, making Texas one of the four lowest ranking states in coverage.
Press briefing to discuss June 21 JAMA article that presents first-ever recommendations for establishment of stroke centers in hospitals is slated for June 20 at National Institutes of Health.
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