A Clean Slate: Engineering the Gut Microbiome with “Good” Bacteria May Help Treat Crohn’s Disease
Perelman School of Medicine at the University of PennsylvaniaPenn Medicine researchers have singled out a bacterial enzyme behind an imbalance in the gut microbiome linked to Crohn’s disease. The new study, published online this week in Science Translational Medicine, suggests that wiping out a significant portion of the bacteria in the gut microbiome, and then re-introducing a certain type of “good” bacteria that lacks this enzyme, known as urease, may be an effective approach to better treat these diseases.