Currently, very few vaccines can be administered orally. Using a novel imaging method that captures all of the immune cells’ niches within an organ, Weizmann Institute scientists investigated the training process for the cells involved in immunity, developing insights that could lead to the design of more effective oral vaccines.
The Weizmann Institute's Prof. Oded Aharonson, who is head of the SpaceIL international science team, has designed a project to measure and examine the Moon's magnetic field. The moon landing will make Israel the fourth country to reach the rocky outpost.
Weizmann Institute scientists Profs. Avihai Danon and Uri Alon find that, like an eye’s adjustment to sudden changes in light, plants have sensitive mechanisms to protect their leaves from rapid changes in radiation
Weizmann Institute scientists have found that, like sophisticated equipment prone to breaking down, our highly advanced brains are more likely to have problems, including depression, autism, and ADHD.
Weizmann Institute of Science researchers took part in the last phase of the 20-year mission - and their work revealed some surprising attributes of Saturn
The Weizmann Institute's Prof. Valery Krizhanovsky and Dr. Yossi Ovadya have found a way to get the body to clear out senescent cells, which are involved in a number of age-related diseases. Treated mice showed improved blood and activity tests, younger-looking tissues, and lived longer than their untreated counterparts.
The new Sherman Institute will advance basic research on novel therapies for a range of disorders, including autoimmune, neurodegenerative, and infectious diseases, as well as cancer.
Controlling the mechanism, found by the lab of Weizmann Institute scientist Prof. Mike Fainzilber, may lead to better therapies for anxiety
Weizmann Institute scientists Profs. Ido Amit and Amos Tanay, working with hemato-oncologists, have created a new way to profile myeloma tumor cells. The machine-learning-based technique will allow earlier and better diagnosis of the cancer, including in terms of relapse, and improve treatment.
A Weizmann Institute team develops a novel technology for profiling protein turnover and degradation, offering new insight into diagnosis and the molecular basis of autoimmunity, cancer, neurodegeneration, and other disorders
Prof. Yardena Samuels of the Weizmann Institute, working with a global team, has developed a way to target a patient's unique melanoma cells. The immunotherapy creates, in effect, a new drug for each person.
Two Weizmann Institute scientists, Profs. Eran Elinav and Eran Segal, have revealed that our gut microbes' relationship with probiotics may not be as healthy as we think
The Weizmann Institute of Science's Prof. Barak Dayan has devised a logic gate that enables atoms and photons to securely exchange information.
Continuing his groundbreaking p53 studies, the Weizmann Institute of Science’s Prof. Moshe Oren has shown how cancer cells within the tumor microenvironment – in particular, within the fibroblasts – can “brainwash” the p53 gene into helping cancer spread, rather than fighting it.
In 1924, Russian biochemist Alexander Oparin claimed that life developed through chemical changes of organic molecules. The Weizmann Institute’s Prof. Doron Lancet has now made discoveries about lipids that support Oparin’s ideas. Lancet’s findings could also help identify early, lipid-based life forms on other worlds.
Drug resistance is an all-too-common occurrence in cancer treatment. Now, working with physicians at Chaim Sheba Medical Center, the Weizmann Institute of Science’s Prof. Yossi Yarden has identified a three-drug combo that fends off drug resistance in lung cancer. This is particularly promising, as two of the medications are already in use.
A new analysis indicates that if the land used to support animal-based diets were instead used for food crops, it would add enough food to feed a further 350 million people – more than the entire population of the U.S.
Part of NASA’s historic Juno mission to Jupiter, the Weizmann Institute's Prof. Yohai Kaspi and colleagues have revealed that the depth of Jupiter’s winds is far greater than expected.
Weizmann Institute scientists bring together physics and biology to create a new model of brain development.
The Weizmann Institute of Science's Prof. Rotem Sorek has conducted a systematic study that uncovered multiple new and unusual bacterial immune defense mechanisms which could pave the way toward new biotech tools
The larvae of the fish that live in coral reefs look alike, making it difficult for marine biologists to study reef populations. Now, Weizmann's Prof. Rotem Sorek found a way to “barcode” 80% of fish species known to visit the reefs in a Red Sea gulf.
Weizmann Institute and colleagues at the University of Copenhagen identify new dates for a 15,000-year-old site in Jordan, challenging some prevailing assumptions about the beginnings of permanent settlements
The Weizmann Institute's Prof. Noam Sobel has found that persons with autism spectrum disorder (ASD) and neurotypical persons reacted differently to the "smell of fear" and "calm sweat" - in fact, they reacted in opposite ways.
Weizmann Institute scientists find that including “non-ideal” components in the design may be key to functional artificial proteins
Dr. Igor Ulitsky has found that ancient genes that lost their ability to make proteins were “recycled,” surviving across millennia – and species – by evolving to produce a type of RNA that regulates major biological processes. His findings could lead to treatments for a number of genetic diseases.
Prof. Daniel Zajfman's universal ion trap cools to a tenth of a degree above absolute zero. The new method does not depend on the type or the weight of the ion and, thus, might be used to investigate the properties of large biological molecules or nanoparticles, among other things.
Dr. Ravid Straussman and colleagues have discovered that bacteria not only live in pancreatic cancer, but are able to render a chemo drug ineffective. Fortunately, it appears that taking antibiotics allows the chemo to work again.
Training at altitude – meaning under low-oxygen conditions – turns athletes into super-performers. Likewise, Prof. Guy Shakhar has found, oxygen-starved T cells become super-effective at attacking cancer. These T cells could provide an immediate way to improve cancer immunotherapy.
Weizmann Institute scientists find that self-assembling protein complexes based on a single mutation could provide scaffolding for nanostructures
The Weizmann Institute's Prof. Eran Bouchbinder has a new theory about why materials usually fail along the edges of a crack. His method will help calculate and predict the behavior of cracks in different materials and different conditions. In a separate project, he advanced understanding of the “glassy state” of matter.
Weizmann Institute of Science researchers used aeronautical engineering to devise a simple method of reducing shockwaves and brightening beams. The method was inspired by the similarity of the “skimmers” used in physics experiments to the air intake mechanisms on air and spacecraft.
Shortly after birth, hearts are no longer able to repair damage. Weizmann Institute scientists found a molecule in newborn hearts that appears to control the renewal process, and seems to “unlock” it in adult hearts; this has important implications for restoring the function of damaged hearts.
Profs. Michal Schwartz and Ido Amit at the Weizmann Institute of Science have discovered a unique immune cell type whose regulated activation may form the foundation of a future treatment for Alzheimer’s disease
Researchers at the Weizmann Institute of Science have found that in utero exposure to stress, then experiencing stressors after birth, can lead to overeating disorders in females. However, the scientists were able to prevent the onset of the disorders through dietary intervention.
A new study at the Weizmann Institute of Science reveals that there is no difference between the health effects of “wholesome” and white bread – rather, one’s gut microbiome affects individual response.
Prof. Boris Rybtchinski has created membranes comprised mostly of water, that self-assemble in water. They can filter out particles based on size, and can be easily disassembled. Crafting nanomaterials that are also sustainable is a major goal of Prof. Rybtchinski’s lab.
Dr. Ayelet Erez, a doctor and geneticist at the Weizmann Institute of Science, has found that while a lack of the protein citrin slows children’s growth, blocking it in cancer slows tumor growth
The Weizmann Institute of Science’s Dr. Valery Krizhanovsky finds that old cells might be useful after all. Understanding why some “retired” cells do not undergo apoptosis could lead to treatments for old-age-related diseases.
The lab of Prof. Alon Chen has found that, besides the classic stress response – an acute reaction that gradually abates when the threat passes – our bodies appear to have a separate mechanism that deals only with chronic stress. These findings may lead to better diagnosis of and treatment for anxiety and depression.
Splitting water molecules to produce hydrogen for fuel holds great promise for alternative energy. However, current methods of water splitting also form undesirable hydrogen peroxide. Now, Israeli and Dutch scientists have found a way to control the spin of electrons, resulting in hydrogen-peroxide-free water splitting
How were the Earth’s solid deposits of iron ore created? Dr. Itay Halevy suggests that, billions of years ago, “green rust” formed in seawater and sank to the ocean bed, becoming an original source of banded iron formations. While this would have been just one means of iron deposition, green rust seems to have delivered a large proportion of iron to our early ocean.
How do white blood cells - the immune cells that race to the sites of infection and inflammation - actually get to their targets? The research of Prof. Ronen Alon has revealed that the white blood cells actually force their way through the blood vessel walls to reach the infection, creating large holes.
Malaria is still a global scourge, killing mostly children in tropical regions. Developing an affordable vaccine that can stay stable without refrigeration is a challenge. Now, a Weizmann Institute lab has reprogrammed proteins in such a way that they could lead to an inexpensive vaccine that can be stored at room temperature.
For the first time, viruses have been found to communicate with one another, leaving short “posts” for kin and descendants. The messages help the viruses reading them decide how to proceed with the process of infection, according to Weizmann Institute research.
Bats – like humans – can find their favorite fruit stand (or coffee shop) even when it’s hidden behind a screen or tall buildings. How? The Weizmann Institute of Science’s Prof. Nachum Ulanovsky and team have now identified the neurons that point bats in the right direction, even when their destination is obscured. This could aid understanding of some aspects of Alzheimer’s.
Nearly a thousand computer simulations by the Weizmann Institute’s Prof. Oded Aharonson and his team produced results challenging the theory that the Moon was formed by a single massive collision; rather, the investigation shows, the more likely explanation is that multiple impacts produced many moonlets, which coalesced into our solitary satellite.
The fine art of mixing drug cocktails is incredibly complicated, with virtually infinite numbers of possible interactions and side effects. Now, a new model from the Weizmann Institute lab of Prof. Uri Alon lets scientists compare combinations of drugs to determine efficacy – a major step forward in personalized medicine.
The wild faba – today, fava – bean is believed to be extinct. Dr. Elisabeth Boaretto has identified the oldest known faba beans – about 14,000 years old. Understanding how the wild fabas survived can help scientists grow hardier fava crops today. Favas are a major source of nutrition in many parts of the world
We watch crystallization take place every winter when ice crystals form on our windows. But no one had ever seen it happen at the molecular level – until now. The Weizmann Institute’s Prof. Ronny Neumann and colleagues have created a way to observe this phase of crystallization, verifying long-held theories.
The low pressure in airplanes can make traveling unpleasant – but it could also ease jetlag, finds the Weizmann Institute’s Dr. Gad Asher. Every cell in the body contains a circadian clock, and when these clocks are disrupted, imbalances result. Dr. Asher’s findings could affect how airlines moderate cabin pressure.
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