Differential expression of HEBP2 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Feature Channels: Biotech
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Released: 29-Oct-2022 12:00 PM EDT
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of GPR160 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of PPM1K in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 29-Oct-2022 12:00 PM EDT
miR-223 Plays A Critical Role in Obesogen-Enhanced Adipogenesis in Mesenchymal Stem Cells and in Transgenerational Obesity
PreprintsRichard C Chang, Erika M. Joloya, Zhuorui Li, Bassem M Shoucri, Toshi Shioda, Bruce Blumberg
Released: 29-Oct-2022 12:00 PM EDT
Differential expression of DST in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 28-Oct-2022 12:00 PM EDT
Assessment Of 3D Printed Polycaprolactone, Hydroxyapatite Nanoparticles and Polyethylene Glycol Diacrylate Scaffolds for Bone Regeneration
PreprintsAna Catarina Sousa, Sara Biscaia, Rui Alvites, Mariana Branquinho, Bruna Lopes, Patrícia Sousa, Joana Valente, Margarida Franco, José Domingos Santos, Carla Mendonça, Luís Atayde, Nuno Alves, Ana Colette Maurício
Released: 28-Oct-2022 12:00 PM EDT
The Tumor Microenvironment in Tumorigenesis and Therapy Resistance Revisited
Preprints
Released: 28-Oct-2022 12:00 PM EDT
Extracellular vesicles promote lipid raft formation in human microglia through TLR4, P2X4R, and αVβ3/αVβ5 signaling pathways
PreprintsAugustas Pivoriūnas
Released: 28-Oct-2022 12:00 PM EDT
High levels of m6A methylation and histone acetylation modification patterns contribute to the survival of LUAD patients
PreprintsLiguo Jia, Zhenzhen Gao, Jing Chen
Released: 28-Oct-2022 12:00 PM EDT
Extract of Plastrum Testudinis through miR-214 mediated Wnt/β-catenin signaling stimulating bone formation
PreprintsQing Lin, Yumei Yang, Xiaoyun Li, Haoyu Wang, Yan Cui, Panpan Wang, Xiaofeng Zhu, Li Yang, Ronghua Zhang
Released: 28-Oct-2022 12:00 PM EDT
Temporary knockdown of p53 during focal limb irradiation increases the development of sarcomas
PreprintsAndrea R. Daniel, Chang-Lung Lee, Chang Su, Nerissa T. Williams, Zhiguo Li, Jianguo Huang, Omar Lopez, Lixia Luo, Yan Ma, Lorraine De Silva Campos, Sara R. Selitsky, Jennifer L. Modliszewski, Siyao Liu, Yvonne M. Mowery,
Released: 28-Oct-2022 12:00 PM EDT
Induction of telomerase in p21-positive cells counteracts capillaries rarefaction in aging mice lung
PreprintsLarissa Lipskaia, Marielle Bréau, Christelle Cayrou, Dmitri Churikov, Laura Braud, Charles Fouillade, Sandra Curras-Alonso, Serge Bauwens, Frederic Jourquin, Frederic Fiore, Rémy Castellano, Emmanuelle Josselin, Carlota Sánchez-Ferrer,
Released: 28-Oct-2022 12:00 PM EDT
Achieving permanent transplant tolerance via reverse chimeras in orthotopic liver transplantation
PreprintsGaofeng Tang, Huibo Zhao, Guoyong Chen
Released: 28-Oct-2022 12:00 PM EDT
Human T2D associated gene IMP2/IGF2BP2 promotes the commitment of mesenchymal stem cells into adipogenic lineage
PreprintsLaura Regue, William Wang, Fei Ji, Joseph Avruch, Hua Wang, Ning Dai
Released: 28-Oct-2022 12:00 PM EDT
Advanced glycation end products inhibit the osteogenic differentiation potential of adipose‐derived stem cells in mice through autophagy
PreprintsTing Fu, Fangzhi Lou, Qiang Zhu, Shuyu Cai, Shuanglin Peng, Jingang Xiao
Released: 28-Oct-2022 12:00 PM EDT
Protein aggregation and calcium dysregulation are the earliest hallmarks of synucleinopathy in human midbrain dopaminergic neurons
PreprintsGurvir S Virdi, Minee Liane Choi, James R Evans, Zhi Yao, Dilan Athauda, Stephanie Strohbuecker, Anna I Wernick, Haya Alrashidi, Daniela Melandri, Jimena Perez-Lloret, Plamena R Stroh, Sergiy Sylantyev, Simon Eaton, Simon Heales,
Released: 28-Oct-2022 12:00 PM EDT
Transcriptional regulation profiling reveals PPARA-mediated fatty acid oxidation as a novel therapeutic target in phospholamban R14del cardiomyopathy
PreprintsMagdalena Harakalova, Jiayi Pei, Renee Maas, Karen Gaar-Humphreys, Johannes Gho, Emilia Nagyova, Christian Snijders Blok, Iris van Adrichem, René van Es, Shahrzad Sepehrkhouy, Dries Feyen, Noortje Van Den Dungen, Nico Lansu, Jorg Cal
Released: 27-Oct-2022 4:15 PM EDT
UT Southwestern Ranked No. 1 in Texas, Fourth in Nation for Tech Transfer
UT Southwestern Medical CenterUT Southwestern Medical Center ranked fourth in the nation and No. 1 in Texas for commercializing new biomedical technologies
Released: 27-Oct-2022 12:00 PM EDT
iPSC-derived cells lack immune tolerance to autologous NK-cells due to imbalance in ligands for activating and inhibitory NK-cell receptors
PreprintsMargarita E. Bogomiakova, Elizaveta K. Sekretova, Ksenia S. Anufrieva, Polina O. Khabarova, Anastasia N. Kazakova, Pavel A. Bobrovsky, Tatiana V. Grigoryeva, Artem V. Eremeev, Olga S. Lebedeva, Alexandra N. Bogomazova, Maria A. Lagarkova
Released: 27-Oct-2022 12:00 PM EDT
3D-printed Strontium-Titanium Scaffolds Incorporated with Highly Bioactive Serum Exosomes Promotes Critical Bone Defect Repair by Enhancing Osteogenesis and Angiogenesis
PreprintsHao Liu, Ranli Gu, Wei Li, Lijun Zeng, Yuan Zhu, Siyi Wang, Xuenan Liu, Boon Chin Heng, Yunsong Liu, Yongsheng Zhou
Released: 27-Oct-2022 12:00 PM EDT
Antimicrobial peptide-loaded decellularized placental sponge as an excellent antibacterial skin substitute against XDR clinical isolates
PreprintsHatef Ghasemi Hamidabadi, Sanaz Alizadeh, Leila Mahboobi, Zahra Khosrowpour, Maryam Nazm Bojnordi, Zahra Aliakbar Ahovan, Majid Malekzadeh Shafaroudi, Maria Zahiri, Narendra Pal Singh Chauhan, Mazaher Gholipourmalekabadi
Released: 27-Oct-2022 12:00 PM EDT
Transcription factor HSFA7b controls ethylene signaling and meristem maintenance at the shoot apical meristem during thermomemory
PreprintsSheeba John, Federico Apelt, Amit Kumar, Dominik Bents, Maria Grazia Annunziata, Franziska Fichtner, Bernd Mueller-Roeber, Justyna J. Olas
Released: 27-Oct-2022 12:00 PM EDT
Tumor-educated Gr1+CD11b+cells instigate breast cancer metastasis by twisting cancer cells plasticity via OSM/IL6-JAK signaling
PreprintsSanam Peyvandi, Manon Bulliard, Annamaria Kauzlaric, Oriana Coquoz, Yu-Ting Huang, Nathalie Duffey, Laetitia Gafner, Girieca Lorusso, Nadine Fournier, Qiang Lan, Curzio Rüegg
Released: 27-Oct-2022 12:00 PM EDT
In vitro treatment of Murine splenocyte with mesenchymal stem cell derived extracellular vesicles altered the mRNA levels of master regulators gene of T cell subsets
PreprintsAlireza Yeganeh, Anwar Fathollahi, Seyed Mahmoud Hashemi, Farshid Yeganeh
Released: 27-Oct-2022 12:00 PM EDT
Influential factors for optimizing and strengthening mesenchymal stem cells and hematopoietic stem cells co-culture
PreprintsMandana Shirdarreh, Fatemeh Amiri, Mohammad Pouya Samiee, Armita Safari
Released: 27-Oct-2022 12:00 PM EDT
KDM6A/UTX promotes spermatogenic gene expression across generations but is dispensable for male fertility
PreprintsBenjamin William Walters, Shannon R Rainsford, Nicolas Dias, Xiaofang Huang, Dirk G de Rooij, Bluma J Lesch
Released: 26-Oct-2022 6:25 PM EDT
New Gene Editing Strategy Could Lead to Treatments for People Born with Inherited Diseases of the Immune System
University College LondonA fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.
Released: 26-Oct-2022 12:00 PM EDT
Maternal inappropriate calcium intake aggravates dietary-induced obesity in male offspring by affecting the differentiation potential of mesenchymal stem cells
World Journal of Stem CellsBACKGROUNDThe effects of inappropriate dietary calcium intake in early life on later obesity have not been fully elucidated. AIMTo raise the mechanism of maternal calcium intake on the multi-differentiation potential of mesenchymal stem cells
Released: 26-Oct-2022 12:00 PM EDT
Exosomes from circ-Astn1-modified adipose-derived mesenchymal stem cells enhance wound healing through miR-138-5p/SIRT1/FOXO1 axis regulation
World Journal of Stem CellsBACKGROUNDWound healing impairment is a dysfunction induced by hyperglycemia and its effect on endothelial precursor cells (EPCs) in type 2 diabetes mellitus. There is increasing evidence showing that exosomes (Exos) derived from adipose-derive
Released: 26-Oct-2022 11:35 AM EDT
Synthetic Genetic Circuits Reprogram Plant Roots
Department of Energy, Office of ScienceControlling gene activity is important for engineering plants for improved bioenergy crops and other applications. This research developed synthetic genes that use Boolean logic gates to achieve specific patterns of gene expression within a plant. The researchers used these gene circuits to redesign the root architecture by tuning the number of root branches.
Released: 26-Oct-2022 8:30 AM EDT
FAU Lands $1.2 Million NSF Grant to Transform Prosthetic Hand Control
Florida Atlantic UniversityCurrent prosthetic hands have five individually actuated digits, yet only one grasp function can be controlled at a time, which makes sophisticated tasks largely impossible.
Released: 26-Oct-2022 12:05 AM EDT
Saliva, Genomic Analysis Used to Identify Promising Biomarkers for Persistent Post-Concussive Symptoms in Children
Nationwide Children's HospitalIn a study published in Frontiers in Public Health, researchers at Nationwide Children’s Hospital have demonstrated a method by which increased risk of persistent post-concussive symptoms (PPCS) in children with concussion can be identified. This could allow families and their care teams to better assess recovery time of children with concussion.
Released: 25-Oct-2022 5:30 PM EDT
Magnetic Sensors Track Muscle Length
Massachusetts Institute of Technology (MIT)Using a simple set of magnets, MIT researchers have come up with a sophisticated way to monitor muscle movements, which they hope will make it easier for people with amputations to control their prosthetic limbs.
Released: 25-Oct-2022 12:55 PM EDT
COUR Pharmaceuticals Announces FDA Clearance of Investigational New Drug Application for Myasthenia Gravis
COUR PharmaceuticalsCOUR Pharmaceuticals, a clinical-stage biotechnology company developing novel immune-modifying nanoparticles designed to reprogram the immune system for the treatment of autoimmune disorders (COUR NanoParticles or CNPs), today announced that the U.S. Food and Drug Administration has cleared an Investigational New Drug (IND) application to initiate a Phase 1b/2a proof-of-concept study of COUR's investigational therapy, CNP-106.
Released: 24-Oct-2022 5:15 PM EDT
The New York Stem Cell Foundation Names Dr. Derrick Rossi as Interim CEO
New York Stem Cell Foundation (NYSCF)The New York Stem Cell Foundation (NYSCF) announced Dr. Derrick Rossi, a member of the NYSCF Board of Directors and co-founder of Moderna, as Interim CEO of NYSCF.
Released: 24-Oct-2022 10:05 AM EDT
SMU biotech research moving into Dallas' Pegasus Park
Southern Methodist UniversitySMU will have space in the Pegasus Park Tower, the centerpiece of a 23-acre mixed-use office campus for biotech firms and nonprofit organizations. Pegasus Park is within minutes of downtown Dallas and the UT Southwestern Medical District.
Released: 21-Oct-2022 4:05 PM EDT
Medical Conference: Italian and American Perspectives on Cancer Care
Sbarro Health Research Organization (SHRO)The Sbarro Health Research Organization (SHRO), in collaboration with Temple University’s College of Science and Technology, the National Italian American Foundation (NIAF), and the Giovan Giacomo Giordano Foundation will host the Medical Conference titled “Italian and American Perspectives on Cancer Care” on Saturday October 29th at 9:00 AM at the Omni Shoreham Hotel in Washington, DC.
Released: 21-Oct-2022 3:15 PM EDT
New-Generation Tests. Russian Scientists Created a Platform for New-Generation Express-Tests on the Base of Crispr-cas12
Scientific Project LomonosovThe development of molecular biology and biotechnologies made it possible to create a lot of biosensors and diagnostic tests – from fast analyses on COVID-19 to express-tests on pathogens, striking agricultural plants. Scientists from The Federal Research Centre “Fundamentals of Biotechnology” of the Russian Academy of Sciences created a platform DIRECT2, that can give birth to new-generation express tests on the base of system CRISPR-Cas12, and demonstrated its work on the example of DNA Dickeya solani – a bacterium, that harms agricultural plants.
Released: 21-Oct-2022 12:00 PM EDT
Short-term exposure of human minor salivary gland stem cells to hypergravity enhances stemness
PreprintsJeong-Seok Choi, Tri Ho Minh, Jeong Mi Kim, Mi Eun Choi, Eun Jeong Jeon, Jin-Mi Park, Sungryeal Kim, Young Mo Kim
Released: 21-Oct-2022 12:00 PM EDT
Differential expression of HEPH in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 21-Oct-2022 12:00 PM EDT
Differential expression of DNAI2 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of CXCL8 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of ALOX15 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of DUSP6 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of STX17-AS1 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of PSMD5-AS1 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of WNT16 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of GREM2 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Comprehensive analysis of m6A related gene mutation characteristics and prognosis in colorectal cancer
PreprintsTao Jiang, Linshuai Xing, Lipeng Zhao, Ziqi Ye, Dong Yu, Shengtao Lin
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