Gilteritinib-induced severe immune-related enteritis: a possible case report
PreprintsPan Luo, Huiyin Qiu, Yushan Yang, Jiaqi Wu, Xianmin Song, Guorong Fan, Gaolin Liu, Junwei Gao
Feature Channels: Stem Cells
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Released: 18-Aug-2022 12:00 PM EDT
Released: 18-Aug-2022 12:00 PM EDT
hucMSC-derived exosomes ameliorate pressure ulcers by inhibiting HMGB1.
PreprintsFei Yan, Meihua Gong, Fu-Rong Li, Li Yu
Released: 18-Aug-2022 12:00 PM EDT
Mesenchymal stromal cell encapsulation in uniform chitosan beads using microchannel emulsification
PreprintsDongjin S Shin, Francesco K Touani, Damon G.K Aboud, Anne Kietzig, Sophie Lerouge, Corinne A Hoesli
Released: 18-Aug-2022 12:00 PM EDT
Loss of LRP1 in adult neural stem cells impairs migration to ischemic lesions
PreprintsKristi Dietert, Swetha Mahesula, Sheetal Hegde, John Verschelde, Pamela Reed, Shane Sprague, Erzsebet Kokovay, Naomi L Sayre
14-Aug-2022 2:05 PM EDT
Why We Fit A Mini Brain with a Mini Cap
Johns Hopkins UniversityIt could be the world’s tiniest EEG electrode cap, created to measure activity in a brain model the size of a pen dot. Its designers expect the device to lead to better understanding of neural disorders and how potentially dangerous chemicals affect the brain. This engineering feat, led by Johns Hopkins University researchers and detailed today in Science Advances, expands what researchers can accomplish with organoids, including mini brains—the lab-grown balls of human cells that mimic some of a brain’s structure and functionality.
Released: 17-Aug-2022 12:00 PM EDT
Deriving Schwann Cells from hPSCs Enables Disease Modeling and Drug Discovery for Diabetic Peripheral Neuropathy
PreprintsHoma Majd, Sadaf Amin, Zaniar Ghazizadeh, Andrius Cesiulis, Edgardo Arroyo, Karen Lankford, Sina Farahvashi, Angeline K Chemel, Mesomachukwu Okoye, Megan D Scantlen, Jason Tchieu, Elizabeth L Calder, Valerie LeRouzic, Abolfazl Arab,
Released: 17-Aug-2022 12:00 PM EDT
Growth of Mesenchymal Stem Cells at the Surface of Silicone, Mineral and Plant-Based Oils
PreprintsLihui Peng, Julien E Gautrot
Released: 16-Aug-2022 4:05 PM EDT
Cell Mapping Close to the Bone
King Abdullah University of Science & Technology (KAUST)Tissues contain many different cell types, and it remains challenging to understand how they interact and contribute to tissue function.
Released: 16-Aug-2022 2:05 PM EDT
Many paths are open to neurons born early
University of BonnWhen it comes to royalty, things are clear: The monarch's first child inherits the crown. Siblings born later must make do with a less glamorous profession.
Released: 16-Aug-2022 12:00 PM EDT
The oncogenic roles of John Cunningham virus T antigen in digestive epithelial cells with tissue specificity
PreprintsHuachuan Zheng, Hang Xue, Ying E, Zhengguo Cui
Released: 16-Aug-2022 12:00 PM EDT
Collagen Ⅰ-DDR1 signaling promotes hepatocellular carcinoma cell stemness via Hippo signaling repression.
PreprintsYi-Xiao Xiong, Xiaochao Zhang, Jing-Han Zhu, Yuxin Zhang, Yonglong Pan, Yu Wu, Jian-Ping Zhao, Junjie Liu, Yuan-Xiang Lu, Huifang Liang, Zhanguo Zhang, Wanguang Zhang
Released: 16-Aug-2022 12:00 PM EDT
Fludarabine/TBI 8 Gy versus fludarabine/treosulfan conditioning in patients with AML in first complete remission: A Study from the Acute Leukemia Working Party of the EBMT
PreprintsGesine Bug, Myriam Labopin, Riitta Niittyvuopio, Matthias Stelljes, Christian Reinhardt, Inken Hilgendorf, Nicolaus Kroeger, Ain Kaare, Wolfgang Bethge, Kerstin Schaefer-Eckart, Mareike Verbeek, Stephan Mielke, Kristina Carlson, Ali
Released: 16-Aug-2022 12:00 PM EDT
Bone Regeneration by Hydroxyapatite-Gelatinnanocomposites
PreprintsSahar I Mostafa, Nesma M Abdelfattah, Sayed M Ghorab, Manal F Osman, Noha A Elwassefy
Released: 16-Aug-2022 12:00 PM EDT
Impact of Pre-transplant Individual Comorbidities on Risk of ICU Admission and Survival Outcomes Following Allogeneic Hematopoietic Stem Cell Transplantation
PreprintsOmer Jamy, John Dasher, Alice Chen, Donna Salzman, Ravi Bhatia, Smita Bhatia
Released: 16-Aug-2022 12:00 PM EDT
Enablers and barriers to referral and delivery of multidisciplinary prehabilitation in the Autologous Stem Cell Transplant population: A theory-based interview study
PreprintsJessica Crowe, Lara Edbrooke, Amit Khot, Linda Denehy, Jill J Francis
Released: 16-Aug-2022 12:00 PM EDT
Implanted hair-follicle-associated pluripotent (HAP) stem cells differentiating to keratinocytes, macrophages and endothelial cells accelerated cutaneous wound closure and suppressed scar formation in a mouse model
PreprintsKoya Obara, Kyoumi Shirai, Yuko Hamada, Nobuko Arakawa, Ayami Hasegawa, Nanao Takaoka, Ryoichi Aki, Robert M. Hoffman, Yasuyuki Amoh
Released: 16-Aug-2022 12:00 PM EDT
Mass spectrometry imaging reveals early metabolic priming of cell lineage in differentiating human induced pluripotent stem cells
PreprintsArina A. Nikitina, Alexandria Van Grouw, Tanya Roysam, Danning Huang, Facundo M. Fernandez, Melissa L. Kemp
Released: 15-Aug-2022 12:00 PM EDT
Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme
PreprintsThe successful generation of endodermal, ectodermal, and most mesodermal lineages from pluripotent stem cells has resulted in basic discoveries and regenerative medicine clinical trials of cell-based therapies.
Released: 15-Aug-2022 12:00 PM EDT
Alcam-a and Pdgfr-α are essential for the development of sclerotome derived stromal cells that support hematopoiesis in vivo.
Preprints: Mesenchymal stromal cells are essential components of hematopoietic stem and progenitor cell (HSPC) niches, regulating HSPC proliferation and fate decisions.
Released: 15-Aug-2022 12:00 PM EDT
Mechanical force sensing drives extrusion of Enterovirus A71-infected cells from colonic epithelial organoids
PreprintsJasmine Moshiri, Ailsa Craven, Sara Mixon, Manuel Amieva, Karla Kirkegaard
Released: 15-Aug-2022 12:00 PM EDT
Single-cell RNA sequencing identifies regulators of differentiation and nutritional cues in Drosophila female germ cells
PreprintsZhipeng Sun, Todd Nystul, Guohua Zhong
Released: 15-Aug-2022 12:00 PM EDT
Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/Syk signaling pathway
PreprintsGuoqiang Yang, Jiraporn Kantapan, Maryam Mazhar, Xue Bai, Yuanxia Zou, Honglian Wang, Bingfeng Huang, Sijing Yang, Nathupakorn Dechsupa, Li Wang
Released: 15-Aug-2022 12:00 PM EDT
Lipids Maintain Genomic Stability and Developmental Potency of Murine Pluripotent Stem Cells
PreprintsLiangwen Zhong, Miriam Gordillo, Xingyi Wang, Yiren Qin, Yuanyuan Huang, Alexey Soshnev, Ritu Kumar, Gouri Nanjangud, Daylon James, C. David Allis, Todd Evans, Bryce Carey, Duancheng Wen
Released: 12-Aug-2022 12:00 PM EDT
Peripherally Inserted Central Venous Catheter for Pediatric Hematologic Diseases; A Retrospective 11-year Single-center Experience.
PreprintsSilvio Ligia, Salvatore Giacomo Morano, Francesca Kaiser, Alessandra Micozzi, Maria Luisa Moleti, Walter Barberi, Fiorina Giona, Antonio Chistolini, Valentina Arena, Alfonso Piciocchi, Maurizio Forgione, Giulia Gasperini, Marco Fabbri, Anna Maria Testi
Released: 12-Aug-2022 12:00 PM EDT
Effect of human breast milk-derived exosomes on the migration and inflammatory response of lipopolysaccharide-exposed dental pulp stem cells
PreprintsEhsaneh Azaryan, Samira Karbasi, Mansoore Saharkhiz, Mohammad Yahya Hanafi-Bojd, Asghar Zarban, Fariba Emadian Razavi, Mohsen Naseri
Released: 11-Aug-2022 2:45 PM EDT
Large number of stem cell lines carry significant DNA damage, say researchers
University of CambridgeDNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable.
Released: 11-Aug-2022 12:00 PM EDT
Micrrosus cirrosus SZ 2021: A potentially new genotype of Micrrosus cirrosus, which can cause fatal pulmonary infection in acute leukemia patients after haplo-HSCT
PreprintsJianjun Cheng, Daxiong Zeng, Ting Zhang, Lu Zhang, Xiu Han, Peng Zhou, Lin Wang, Jun He, Qingzhen Han
Released: 11-Aug-2022 12:00 PM EDT
Deciphering transcriptional networks during human cardiac development
PreprintsRobin Canac, Bastien Cimarosti, Aurore Girardeau, Virginie Forest, Pierre Olchesqui, Jeremie Poschmann, Richard Redon, Patricia Lemarchand, Nathalie Gaborit, Guillaume Lamirault
Released: 11-Aug-2022 12:00 PM EDT
Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel disease mechanism
PreprintsMalte Loos, Birgit Klampe, Thomas Schulze, Xiaoke Yin, Konstantinos Theofilatos, Bärbel Ulmer, Carl Schulz, Charlotta Behrens, Tessa Van Bergen, Eleonora Adami, Henrike Maatz, Michaela Schweizer, Susanne Brodesser, Boris Skryabin,
Released: 11-Aug-2022 12:00 PM EDT
CXCR4 enhances the inhibitory effects of bone mesenchymal stem cells on lung cell apoptosis in a rat model of smoking-induced COPD
PreprintsJiansheng Gao, Yuli Liang, Jiabao Chen, Huihui Shen, Hua Liu
Released: 11-Aug-2022 12:00 PM EDT
Exercise Training Remodels Adipocyte-Specific Extracellular Matrix Proteins and Alters Innervation and Vascularization in Inguinal White Adipose Tissue (iWAT)
PreprintsPasquale Nigro, Maria Vamvini, Jiekun Jackie Yang, Tiziana Caputo, Li-Lun Ho, Danae Papadopoulos, Nicholas Philip Carbone, Royce Colin, Jie He, Hirshman Frederick Michael, Joseph Daniel White, Jacques Robidoux, Robert Hickner, Soeren
Released: 11-Aug-2022 12:00 PM EDT
Development of lacrimal gland organoids from iPSC derived multizonal ocular cells
PreprintsMelis Asal, Gamze Koçak, Vedat Sarı, Tuba Reçber, Emirhan Nemutlu, Canan Aslı Utine, Sinan Guven
Released: 10-Aug-2022 12:00 PM EDT
Severe Combined Immunodeficiency: Improved survival leading to detection of underlying liver disease
PreprintsAnusha Vittal, Nehna Abdul Majeed, Elizabeth Garabedian, Jamie Marko, David E Kleiner, Rob Sokolic, Fabio Candotti, Harry Malech, Theo Heller, Christopher Koh
Released: 10-Aug-2022 12:00 PM EDT
Computational challenges of cell cycle analysis using single cell transcriptomics
PreprintsAlexander Chervov, Andrei Zinovyev
Released: 10-Aug-2022 12:00 PM EDT
Neural Induction: the General Principle for Embryogenesis and Tumorigenesis
PreprintsYing Cao
Released: 10-Aug-2022 12:00 PM EDT
Hematopoietic stem cell transplantation for chronic active Epstein-Barr virus and hydroa vacciniforme-like lymphoproliferative disorder complicated by fatal ruptured cerebral artery aneurysm.
PreprintsTroy Yi, Jeffrey Steinberg, Scott Olson, Howaida El-Said, Jun Mo, Eric Anderson, Nicholas Gloude, Deborah Schiff
Released: 10-Aug-2022 12:00 PM EDT
Epithelium-derived SCUBE3 promotes polarized- odontoblast differentiation of dental mesenchymal stem cells and vascularized pulp regeneration
PreprintsZijie Wang, Chuying Chen, Jiayi Zhang, Jiangdie He, Lin Zhang, Jiayuan Wu, Zhihui Tian
Released: 10-Aug-2022 12:00 PM EDT
PVT1/miR-136/Sox2/UPF1 axis regulates the malignant phenotypes of endometrial cancer stem cells
PreprintsQing Li, Fanfei Kong, Rong Cong, Jian Ma, Cuicui Wang, Xiaoxin Ma
Released: 10-Aug-2022 12:00 PM EDT
Quinolone Prophylaxis Prevents the Development of Carbapenem-Resistant Infection in Patients Undergoing Hematopoietic Stem Cell Transplant
PreprintsRahul Naithani
Released: 10-Aug-2022 12:00 PM EDT
Human brain organoid model of maternal immune activation identifies radial glia cells as selectively vulnerable
PreprintsKseniia Sarieva, Theresa Kagermeier, Shokoufeh Khakipoor, Ezgi Atay, Zeynep Yentuer, Katharina Becker, Simone Mayer
Released: 9-Aug-2022 4:05 PM EDT
See-through zebrafish, new imaging method put blood stem cells in high-resolution spotlight
University of Wisconsin–MadisonMADISON — For the first time, researchers can get a high-resolution view of single blood stem cells thanks to a little help from microscopy and zebrafish.Researchers at the University of Wisconsin–Madison and the University of California San Diego have developed a method for scientists to track a single blood stem cell in a live organism and then describe the ultrastructure, or architecture, of that same cell using electron microscopy.
Released: 9-Aug-2022 12:00 PM EDT
Hypoxia induces early neurogenesis in human fetal neural stem cells by activating the WNT pathway
PreprintsDevanjan Dey, Vadanya Shrivastava, Diksha Joshi, Chitra Mohinder Singh Singal, Sagar Tyagi, Muzaffer Ahmed Bhat, Paritosh Jaiswal, Jai Bhagwan Sharma, Jayanth Kumar Palanichamy, Subrata Sinha, Pankaj Seth, Sudip Sen
Released: 9-Aug-2022 12:00 PM EDT
Activation of the urotensin-II receptor by anti-COVID-19 drug remdesivir induces cardiomyocyte dysfunction
PreprintsFan-Yan Wei, Asuka Inoue, Akiko Ogawa, Seiya Ohira, Tatsuya Ikuta, Yuri Kato, Shota Yanagida, Yukina Ishii, Yasunari Kanda, Motohiro Nishida
Released: 9-Aug-2022 12:00 PM EDT
Mir-4699 Promotes the Osteogenic Differentiation of Mesenchymal Stem Cells
PreprintsVahedeh Hosseini, Mahdi Paryan, Ameneh Koochaki, Henry Manuel Cesaire, Samira Mohammadi-Yeganeh
Released: 9-Aug-2022 12:00 PM EDT
SMPD1 Expression Profile and Mutation Landscape Help Decipher Genotype–Phenotype Association and Precision Diagnosis for Niemann–Pick Disease Types A and B
PreprintsRuisong Wang, Ziyi Qin, Long Huang, Huiling Luo, Han Peng, Xinyu Zhou, Zhixiang Zhao, Mingyao Liu, Pinhong Yang, Tieliu Shi
Released: 9-Aug-2022 12:00 PM EDT
Development and Validation of a Glioma-Associated Mesenchymal Stem Cell-Related Gene Prognostic Index for Predicting Prognosis and Guiding Individualized Therapy in Glioma
PreprintsZesheng Peng, Yuxi Wu, Jiajing Wang, Sujie Gu, Yihao Wang, Bingzhou Xue, Peng Fu, Wei Xiang
Released: 9-Aug-2022 12:00 PM EDT
Adipose tissue-derived stromal/stem cells transplantation + cholecalciferol in recent-onset type 1 diabetes patients: twelve months follow up.
PreprintsJoana Rodrigues Dantas, Débora Batista Araújo, Karina Ribeiro Silva, Débora Lopes Souto, Maria De Fátima Carvalho Pereira, RonirRaggio LUIZ, Cesar Claudio-Da-Silva, Carlos Eduardo Barra Couri, Angelo Maiolino, Carmen Lúcia Kuniyoshi Rebelatto, Débora Regina Daga, Alexandra Cristina Senegaglia,
Released: 8-Aug-2022 2:15 PM EDT
New injectable gel offers promise for tough-to-treat brain tumors
University of Wisconsin–MadisonThe University of Wisconsin–Madison's Cell-Inspired Personalized Therapeutic (CIPT) Lab has developed a powerful immunity-boosting postoperative treatment that could transform the odds for patients with glioblastoma.
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