Focus: Hidden - Minnesota

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ROCHESTER, Minn. — Patients with a low-grade type of brain tumor called glioma who received radiation therapy plus a chemotherapy regimen, including procarbazine, lomustine and vincristine (PCV), experienced a longer progression-free survival and overall survival than patients who received radiation therapy alone, according to the results of the clinical trial, Radiation Therapy Oncology Group (RTOG) 9802 published in the April 7 issue of the New England Journal of Medicine.

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Babies born to pregnant women taking the epilepsy drug lamotrigine may not be at an increased risk of birth defects, such as cleft lip, cleft palate or clubfoot, according to a study published in the April 6, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Patients who arrive at the emergency department with low-risk chest pain and talk through treatment options with a physician show improved knowledge of their health status and follow-up options, compared with patients who received standard counseling from a physician, according to Mayo Clinic research presented at the American College of Cardiology’s 65th Annual Scientific Session.

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At a time when the nation is facing projected physician shortages, a Mayo Clinic study shows an association between burnout and declining professional satisfaction with physicians reducing the number of hours they devote to clinical practice. The findings appear in Mayo Clinic Proceedings.

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While absolute rates of biopsy and post-biopsy complications have decreased following several benchmark prostate-specific antigen (PSA) screening publications, the relative risk for each patient continues to increase, according to a new study by Mayo Clinic researchers.

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New research suggests that looking at structures in the right side of the brain may help predict who will better recover from language problems after a stroke, according to a study published in Neurology®, a medical journal of the American Academy of Neurology.

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Mayo Clinic and vMocion, LLC, an entertainment technology company, today announced it is making available Mayo Clinic’s patented Galvanic Vestibular Stimulation (GVS) technology specifically for use in virtual reality and augmented reality.

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Exercise in older people is associated with a slower rate of decline in thinking skills that occurs with aging. People who reported light to no exercise experienced a decline equal to 10 more years of aging as compared to people who reported moderate to intense exercise, according to a population-based observational study published in the March 23, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Roughly 140,000 people are diagnosed with colorectal cancer in the United States each year. It is the third most common cancer and No. 2 cause of cancer-related deaths among men and women.

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The health benefits of a plant-based diet is well-known, but the question remains: Could vegans be at risk for deficiency of essential nutrients? A retrospective review by Mayo Clinic physicians recently published in the Journal of the American Osteopathic Association indicated that vegans should ensure adequate intake of a few nutrients.

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MINNEAPOLIS – Women may have a better memory for words than men despite evidence of similar levels of shrinkage in areas of the brain that show the earliest signs of Alzheimer’s disease, according to a study published in the March 16, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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U.S. News & World Report today released its 2017 rankings for Best Graduate Schools across the nation. Mayo Medical School and Mayo School of Health Sciences, two schools within Mayo Clinic College of Medicine, advanced significantly in the findings.

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Could an unhealthy diet and lack of exercise be making you age faster? Researchers at Mayo Clinic believe there is a link between these modifiable lifestyle factors and the biological processes of aging. In a recent study, researchers demonstrated that a poor diet and lack of exercise accelerated the onset of cellular senescence and, in turn, age-related conditions in mice. Results appear today in Diabetes.

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Researchers on Mayo clinic’s florida campus have shut down one of the most common and lethal forms of lung cancer by combining the rheumatoid arthritis drug auranofin with an experimental targeted agent.

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Medical students are more prone to alcohol abuse than their peers not attending medical school, especially if they are young, single and under a high debt load. That’s according to a study on medical student burnout by researchers at Mayo Clinic. The findings appear in the journal Academic Medicine.

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With support from the state of Florida, Mayo Clinic’s Florida campus has opened a state-of-the-art laboratory for nanotechnology research, an emerging field of science that studies and applies materials that are the size of an atom.

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People newly diagnosed with multiple sclerosis (MS) may often have other chronic health conditions as well, according to a study published in the March 9, 2016 online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Anyone caring for a loved one with Alzheimer’s disease likely can relate to former first lady Nancy Reagan, who called the illness suffered by former President Ronald Reagan “a truly long, long goodbye.”

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Influenza is a serious viral infection that causes illness, hospitalizations and thousands of deaths every year in the U.S. Mayo Clinic recommends getting a vaccine each year to prevent illness and protect the people around you.

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Young adults with hostile attitudes or those who don’t cope well with stress may be at increased risk for experiencing memory and thinking problems decades later, according to a study published in the March 2, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Keeping the brain active with social activities and using a computer may help older adults reduce their risk of developing memory and thinking problems, according to a study released today that will be presented at the American Academy of Neurology’s 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

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Children who are emotionally abused may be more likely to experience migraines as young adults, according to a preliminary study released today that will be presented at the American Academy of Neurology’s 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016. The link between migraine and abuse was stronger for emotional abuse than for physical or sexual abuse in the study.

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If your neighborhood is well-lit at night, you may not be sleeping well, according to a study released today that will be presented at the American Academy of Neurology’s 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

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A new clinical study from the Mayo Clinic Center for Individualized Medicine shows that whole-exome sequencing (WES) could serve as a viable diagnostic approach for identifying rare inherited diseases and providing a resolution for patients on a diagnostic odyssey.

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Turning the clock ahead or back one hour during daylight saving time transitions may be tied to an increased risk of ischemic stroke, but only temporarily, according to a preliminary study released today that will be presented at the American Academy of Neurology’s 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

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Providing direct care for more than 1.3 million people, Mayo Clinic continues its mission to be a trusted source for clinical quality, medical education and research discoveries. Mayo Clinic reported a strong financial position in 2015, while contributing to its pension plan and capital projects.

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A drug that would be the first to target the cause of Huntington’s disease (HD) is effective and safe when tested in mice and monkeys, according to data released today that will be presented at the American Academy of Neurology’s 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016. A study to test the drug in humans has begun.

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On 25 February 2016, a group of scientific societies, companies, research institutes, and governmental agencies launched the Phytobiomes Roadmap presenting a new vision for agriculture to increase health, productivity, and sustainability of our current cropping and forest systems.

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Most of the 82 Ebola survivors in a new study from the world’s largest Ebola outbreak had brain symptoms more than six months after the initial infection. The preliminary results will be presented at the American Academy of Neurology’s 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016. The study is part of the larger Prevail III study, which follows patients with prior Ebola virus disease and their close contacts who serve as study controls.

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People who keep mentally and physically healthy in middle age may help stave off the symptoms of Alzheimer’s disease, but the activity does not affect the underlying disease changes in the brain for most people, according to a study published in the February 24 online edition of Neurology®, the medical journal of the American Academy of Neurology.

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Keeping the mind active may delay symptoms of Alzheimer’s disease; however, the activity does not change the underlying disease in the brain for most people, according to a study published today in the online edition of Neurology.

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Mayo Clinic will live-stream a colonoscopy on the mobile app Periscope on Tuesday, March 1, at 8:30 a.m. EST. The broadcast is part of Mayo Clinic’s ongoing collaboration with Fight Colorectal Cancer to raise awareness of the importance of colorectal cancer screening. March is Colorectal Cancer Awareness Month.

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When diagnosed with breast cancer, women may have thousands of questions running through their minds, but one they may not have immediately is: Will my choice of provider save me time and money?

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Migraine and tension-type headaches may share genetic links with irritable bowel syndrome (IBS), according to a preliminary study released today that will be presented at the American Academy of Neurology’s 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

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New treatments and diagnostics for Alzheimer’s and cancer dominate the 2016 research awards recently announced by the Minnesota Partnership for Biotechnology and Medical Genomics. The state-supported funding was distributed among seven research teams, based on competitive applications. Each team represents researchers from Mayo Clinic and the University of Minnesota.

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The Mayo Clinic Board of Trustees recognized three retiring members, elected new members and re-elected members at its board meeting today.

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Stenting and surgery are equally effective at lowering the long-term risk of stroke from a narrowed carotid artery, according to results of CREST – a 10-year, federally funded clinical trial led by researchers at Mayo Clinic’s campus in Florida. The results are being published today online in the New England Journal of Medicine and presented at the American Heart Association’s International Stroke Conference in Los Angeles.

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Antibiotics may be linked to a serious disruption in brain function, called delirium, and other brain problems, more than previously thought, according to a “Views and Reviews” article published in the February 17, 2016, online issue of Neurology®, a medical journal of the American Academy of Neurology.

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Mayo Clinic is hosting a grand opening event for Mayo Clinic Building – Phoenix, home to the Mayo Clinic Cancer Center and the new Mayo Clinic Proton Beam Therapy Program — the first such cancer treatment program in the Southwest.

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It may start with a simple word you can’t pronounce. Your tongue and lips stumble, and gibberish comes out. Misspeaking might draw a chuckle from family and friends. But, then, it keeps happening. Progressively, more and more speech is lost. Some patients eventually become mute from primary progressive apraxia of speech, a disorder related to degenerative neurologic disease.

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Building on previous studies, Mayo Clinic researchers have demonstrated significant health improvements in the vascular system of mice following repeated treatments to remove senescent cells. They say this is the first study to show that regular and continual clearance of senescent cells improves age-related vascular conditions – and that the method may be a viable approach to reduce cardiovascular disease and death. The findings appear online in Aging Cell.

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Poor physical fitness in middle age may be linked to a smaller brain size 20 years later, according to a study published in the February 10, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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A kidney transplant is a life-changing and life-saving procedure. Yet, a new study conducted by Mayo Clinic and the University of Michigan shows that only one-third of patients who ultimately receive a living donor kidney transplant receive it pre-emptively (i.e., before starting dialysis). Less than two-thirds receive a transplant either pre-emptively or within a year of starting dialysis.

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Mayo Clinic researchers, in collaboration with the Centers for Disease Control and Prevention (CDC) and health officials from Minnesota, North Dakota and Wisconsin, have discovered a new bacterial species that causes Lyme disease in people. The new species has been provisionally named Borrelia mayonii. Prior to this finding, the only species believed to cause Lyme disease in North America was Borrelia burgdorferi.

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Researchers at the University of Minnesota have engineered a new synthetic biopathway that can more efficiently and cost-effectively turn agricultural waste, like corn stover and orange peels, into a variety of useful products ranging from spandex to chicken feed.

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The incidence of childhood and adult obesity has increased significantly over the past three decades. New research shows that there is an association between obesity development during adulthood and childhood attention deficit hyperactivity disorder (ADHD).

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ROCHESTER, Minn. — In a review article published in the Feb. 4 issue of the New England Journal of Medicine, a pair of Mayo Clinic Cancer Center researchers provide an in-depth look at the issues associated with the care of women in families with hereditary breast and ovarian cancer syndrome who have not yet developed cancer themselves. The article addresses optimal risk assessment for breast and ovarian cancers, the usefulness of risk-reducing surgery, side effects of these procedures, alternative strategies for cancer prevention and the best ways to help with the decision-making process.

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A new study suggests that people with brain injuries following head trauma may have buildup of the plaques related to Alzheimer’s disease in their brains. The research is published in the February 3, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Researchers at Mayo Clinic have shown that senescent cells – cells that no longer divide and accumulate with age – negatively impact health and shorten lifespan by as much as 35 percent in normal mice. The results, which appear today in Nature, demonstrate that clearance of senescent cells delays tumor formation, preserves tissue and organ function, and extends lifespan without observed adverse effects.

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Researchers from Mayo Clinic in Arizona and Banner Sun Health Research Institute have determined that testing a portion of a person's submandibular gland may be a way to diagnose early Parkinson’s disease. The study was published this month in Movement Disorders.