Feature Channels: Stem Cells

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Released: 21-Jul-2022 12:00 PM EDT
Generation of cardiomyocytes from human induced pluripotent stem cells resembling atrial cells with ability to respond to adrenoceptor agonists
Preprints

Faizzan S. Ahmad, Yongcheng Jin, Alexander D. Grassam-Rowe, Yafei Zhou, Meng Yuan, Xuehui Fan, Rui Zhou, Razik Mu-U-Min, Christopher O'Shea, Ayman M. Ibrahim, Wajiha Hyder, Yasmine Aguib, Magdi Yacoub, Davor Pavlovic

Released: 21-Jul-2022 12:00 PM EDT
TLR3 stimulation improves the migratory potency of adipose-derived mesenchymal stem cells through the stress response pathway in the melanoma mouse model
Preprints

Fatemeh Eskandari, Samira Zolfaghari, Ayna Yazdanpanah, Rima Manafi Shabestari, Motahareh Rajabi Fomeshi, Peiman B. Milan, Jafar Kiani, Mina Soufi Zomorrod, Majid Safa

Released: 20-Jul-2022 12:00 PM EDT
Human liver organoids model progressive inflammatory and fibrotic injury in non-alcoholic fatty liver disease
Preprints

Anja Hess, Stefan D. Gentile, Amel Ben Saad, Raza-Ur Rahman, Tim Habboub, Alan C. Mullen

Released: 20-Jul-2022 12:00 PM EDT
Cas9+ conditionally immortalized neutrophil progenitors as a tool for genome wide CRISPR screening for neutrophil differentiation and function
Preprints

Robyn M Jong, Krystal Ching, Nicholas E Garelis, Alex Zilinskas, Xammy Nguyenla, Sagar Rawal, Bianca Hill, Bridget Luckie, Lillian Shallow, Jeffery S Cox, Gregory Barton, Sarah Stanley

Newswise: Lymphatics Help ‘Seed’ Early Brain Cells in Zebrafish
Released: 19-Jul-2022 1:55 PM EDT
Lymphatics Help ‘Seed’ Early Brain Cells in Zebrafish
University of Notre Dame

A recent paper in Nature Neuroscience by University of Notre Dame biologist Cody J. Smith demonstrated how lymphatics — which remove waste from the rest of the body — are also associated with microglia and brain development in zebrafish.

   
Newswise: Scientists Develop Blueprint for Turning Stem Cells Into Sensory Interneurons
Released: 19-Jul-2022 1:05 PM EDT
Scientists Develop Blueprint for Turning Stem Cells Into Sensory Interneurons
University of California, Los Angeles (UCLA), Health Sciences

Key takeaways: • Just like the real thing. The stem cell–derived interneurons, which play a role in sensations like touch and pain, are indistinguishable from their real-life counterparts in the body. • Tomorrow’s therapies. In addition to potential treatments for injury-related sensation loss, the discovery could lead to new methods for screening drugs for chronic pain. • Moving forward. While stem cells from mice were used in the research, scientists are now working to replicate the findings with human cells.

Released: 19-Jul-2022 12:55 PM EDT
Rutgers Scientists Reveal New Evidence of Key Mechanism in Alzheimer’s
Rutgers University-New Brunswick

Rutgers scientists have found more clear-cut evidence of how the destructive proteins linked to Alzheimer’s disease attack human brain cells and destroy surrounding tissue.

   
Released: 19-Jul-2022 12:00 PM EDT
Perfusable Apparatus For Thick-tissue Creation And Growth (patch) Of Cardiac Tissue
Preprints

Amatullah Mir, Isaree Pitaktong, Jason Yusheng He, Katherine Nurminsky, Tyler Dunn, Sarah Koljaka, Olivia Dunn, Stephanie Ran, Daniel Rodgers, Anya Wang, Hiroshi Matsushita, Narutoshi Hibino, Wesley Shih

Released: 19-Jul-2022 12:00 PM EDT
Pyruvate carboxylation identifies Glioblastoma Stem-like Cells opening new metabolic strategy to prevent tumor recurrence
Preprints

Ophelie Renoult, Catherine Gratas, Noemie Joalland, Melanie Laurent--Blond, Hala Awada, Marine Bourgeois, Lisa Oliver, Sophie Chiavassa, Mikael Croyal, Francois Paris, Claire Pecqueur

Released: 19-Jul-2022 12:00 PM EDT
Plant Volatile Signatures of Growth and Defense during Abiotic Stress
Preprints

Kolby Jardine, Rebecca Dewhirst, Suman Som, Joseph Lei, Eliana Tucker, Robert Young P, Miguel Portillo-Estrada, Yu Gao, Luping Su, Silvano Fares, Cristina Castanha, Jenny Mortimer

Released: 19-Jul-2022 12:00 PM EDT
Exosome-shuttled miR-126 mediates ethanol-induced disruption of neural crest cell-placode cell interaction by targeting SDF1
Preprints

Yihong Li, Ting Cai, Huina Liu, Yun Lei, Shun Zhang, Fuyu Sun, Jie Liu, Shao-Yu Chen, Huadong Fan

Released: 19-Jul-2022 10:00 AM EDT
Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero
Cell Stem Cell

Here, Seong et al. identify an optimal set of epiblast inducers that captures mouse trophectoderm stem cells (TESCs) as a stable and highly self-renewing state reflecting the blastocyst stage. TESCs have enhanced capacity to form blastoids that indu

Released: 18-Jul-2022 3:45 PM EDT
Pesquisa da Mayo Clinic analisa por que os pacientes procuram tratamentos com células-tronco
Mayo Clinic

Em um dos primeiros estudos inéditos, a Mayo Clinic analisou um grupo grande de pacientes para entender as motivações para buscar terapias com células-tronco, e se tais expectativas são fundamentadas na ciência.

Released: 18-Jul-2022 3:45 PM EDT
妙佑医疗国际调查患者寻求干细胞疗法的原因
Mayo Clinic

妙佑医疗国际(Mayo Clinic) 在一项开创性调查研究中对一大批患者进行了分析,以了解他们寻求干细胞疗法的动机,以及他们的期望是否具有科学依据。调查发现有助于医务人员破除误导性观念,并更好地为患者提供咨询服务。

Released: 18-Jul-2022 3:40 PM EDT
Encuesta de Mayo Clinic analiza por qué los pacientes solicitan tratamientos con células madre
Mayo Clinic

En uno de los primeros estudios de este tipo, Mayo Clinic analizó a un grupo grande de pacientes para entender qué les motiva a solicitar terapias con células madre y saber si sus expectativas tienen base científica.



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