New guidance published today in Anaesthesia provides actionable steps to mitigate greenhouse gas emissions from inhaled anesthetics, particularly desflurane, which is commonly used in general anesthesia, and nitrous oxide (laughing gas).
According to a paper published in Frontiers in Oncology, daily use of a unique mushroom extract AHCC® supported the immune system in clearing HPV infections in two-thirds of study participants after six months of supplementation.
A retrospective cohort study found that new thiopurine users with the rs2814778-CC genotype variant, a gene more common in persons of African ancestry, experienced azathioprine discontinuation due to hematopoietic toxicity at an almost 3-fold higher rate than patients with other genotypes. Based on their results, the authors recommend that testing for the Duffy-null phenotype be considered in all patients before azathioprine initiation or if leukopenia is detected while a patient is using azathioprine. The findings are published in Annals of Internal Medicine.
A brief research report found that Medicare could have saved up to $3.6 billion by purchasing generic drugs at the same prices as the Mark Cuban Cost Plus Drug Company (MCCPDC) in 2020. These findings suggest that Medicare is overpaying for some generic drugs. The report is published in Annals of Internal Medicine.
Researchers used mice to develop a mathematical model of a myocardial infarction, popularly known as a heart attack.
The Rutgers School of Public Health has launched New Jersey’s first Master of Science (MS) in Epidemiology with a concentration in Pharmacoepidemiology degree. This new program will begin enrolling full-time and part-time students for the Fall 2022 semester.
The cost of brand-name drugs for epilepsy increased by 277% from 2010 to 2018, according to a study published in the June 15, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. The cost of generic drugs for epilepsy decreased by 42% over the same period.
Biomedicines are produced by living cells and are used to treat cancer and autoimmune diseases among other things.
Fentanyl, a mu-opioid receptor agonist, is one of the most commonly used analgesics in the hospital and may induce long-lasting behavioral and somatosensory impairment in rodents.
If you’ve ever swallowed the same round tablet in hopes of curing everything from stomach cramps to headaches, you already know that medicines aren’t always designed to treat precise pain points.
Valproic acid (VPA) keeps nervous system cells from growing and dividing correctly, researchers discovered.
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A “quality management maturity” (QMM) rating system for pharmaceutical manufacturing facilities is viable toward reducing drug shortages and increasing medicine availability, according to research by risk management expert Clifford Rossi at the University of Maryland.
The novel coronavirus disease 2019 (COVID-19) is the third coronavirus outbreak in the last two decades.
In a new Annals ‘Beyond the Guidelines’ feature, a preventive cardiologist and a general internist discuss their approach to the use of statins for primary prevention of cardiovascular disease (CVD) and how they would apply the guidelines to an individual patient. All ‘Beyond the Guidelines’ features are based on the Department of Medicine Grand Rounds at Beth Israel Deaconess Medical Center (BIDMC) in Boston and include print, video, and educational components published in Annals of Internal Medicine.
A randomized controlled trial (RCT) comparing spinal versus general anesthesia for hip surgery found that spinal anesthesia was associated with worse pain immediately after surgery and higher rates of pain reliever prescriptions at 60 days. However, differences in pain, satisfaction, or mental status between the two interventions seemed to diminish at 60, 180, or 365 days after surgery. The findings are published in Annals of Internal Medicine.
Plastic pollution in the ocean may serve as a source for novel antibiotics, according to a new student-led study conducted in collaboration with the Scripps Institution of Oceanography. The research will be presented at the American Society for Microbiology’s conference in Washington, D.C. on June 9-13, 2022.
A newly published study by University of Calgary researchers reveals a potential new way to treat chronic pain using anti-cancer drugs rather than opioid-based pain medication.
Harrington Discovery Institute® at University Hospitals in Cleveland, Ohio, and its registered UK charity Fund for Cures UK, Ltd. (Fund for Cures UK) have issued a call for proposals for the 2023 Harrington UK Rare Disease Scholar Award. In addition to grant funding, Harrington Discovery provides guidance and oversight in drug development, while intellectual property is retained by the scholar and their institution.
Scientists have reported good news on the pandemic preparedness front: A cocktail of four manufactured antibodies is effective at neutralizing a virus from the Henipavirus family, a group of pathogens considered to be a global biosecurity threat.
A study led by the Duke Clinical Research Institute (DCRI) in partnership with Vanderbilt University found no differences in relief of mild-to-moderate COVID-19 symptoms between participants taking ivermectin and participants taking a placebo.
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