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Irvine, Calif., Feb. 9, 2021 — Monoclonal antibodies are showing promise for improving outcomes for COVID-19 patients, but when a hospital is already beyond capacity, administering them can be a challenge. As hospitalizations soared across California, clinicians with UCI Health created a system for delivering monoclonal antibodies that is keeping hospital beds available for patients with the greatest need.

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Irvine, Calif., Feb. 4, 2021 — A newly established Institute for Future Health at the University of California, Irvine will combine research and clinical work to address the movement toward a more personalized healthcare model. The institute aims to integrate lifestyle, community, environment and socioeconomic factors in conjunction with biomedical and clinical knowledge to radically transform health systems away from hospitals and clinics and into the hands of each individual.

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Irvine, Calif., Feb. 1, 2021 — Researchers from the University of California, Irvine and the University of Minnesota have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin. They also discovered that duloxetine, an antidepressant that boosts serotonin levels, could be an alternative to opioids in treating chronic pain.

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Irvine, Calif., Jan. 27, 2021 — A $100,000 research and planning grant from the Getty Foundation will allow The Beall Center for Art + Technology to join the third regional collaboration in the Getty’s Pacific Standard Time: Art x Science x LA. Forty-five cultural, educational and scientific institutions throughout Southern California will receive support for their projects, all of which will explore the intersection of art and science.

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A new University of California, Irvine-led study finds a new method for identifying biomarkers may aid in early cancer diagnosis. The study focused on lung cancer, however the Cell Heterogeneity-Adjusted cLonal Methylation (CHALM) method has been tested on aging and Alzheimer’s diseases as well and is expected to be effective for studying other diseases.

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Irvine, Calif., Jan. 27, 2021 — One of President Joe Biden’s first post-inauguration acts was to realign the United States with the Paris climate accord, but a new study led by researchers at the University of California, Irvine demonstrates that rising emissions from human land-use will jeopardize the agreement’s goals without substantial changes in agricultural practices.

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Irvine, Calif., Jan. 26, 2021 — The University of California, Irvine Master of Advanced Study in criminology, law & society has been named the nation’s best online criminal justice master’s program by U.S. News & World Report for the second year in a row. The 2021 rankings also mark the fourth consecutive year in which UCI has placed in the top three.

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Irvine, Calif., Jan. 25, 2021 — Scientists at the University of California, Irvine and NASA’s Jet Propulsion Laboratory have for the first time quantified how warming coastal waters are impacting individual glaciers in Greenland’s fjords. Their work is the subject of a study published recently in Science Advances. Working under the auspices of the Oceans Melting Greenland mission for the past five years, the researchers used ships and aircraft to survey 226 glaciers in all sectors of one of Earth’s largest islands.

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Irvine, Calif., Jan. 21, 2021 — Plans to build a world-class, acute care hospital on the northern edge of the University of California, Irvine academic campus advanced significantly today, as the University of California Board of Regents granted approval of the project’s 144-bed acute care facility, ambulatory care center and cancer center.

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Irvine, Calif., Jan. 18, 2021 — Future climate change will cause a regionally uneven shifting of the tropical rain belt – a narrow band of heavy precipitation near the equator – according to researchers at the University of California, Irvine and other institutions. This development may threaten food security for billions of people.

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Irvine, Calif., Jan. 12, 2021 — A $10.4 million gift to the University of California, Irvine from the Steckler Charitable Fund, formed by Vincent and Amanda Steckler, will support art history students as well as the creation of a center committed to making the field of computing more inclusive. Vincent Steckler, who earned both a B.

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Irvine, Calif., Jan. 11, 2021 – Often admired for their flawless appearance to the naked eye, crystals can have defects at the nanometer scale, and these imperfections may affect the thermal and heat transport properties of crystalline materials used in a variety of high-technology devices. Employing newly developed electron microscopy techniques, researchers at the University of California, Irvine and other institutions have, for the first time, measured the spectra of phonons – quantum mechanical vibrations in a lattice – at individual crystalline faults, and they discovered the propagation of phonons near the flaws.

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Irvine, Calif., Jan. 7, 2021 – Students from the University of California, Irvine are self-publishing a book about their lives during the COVID-19 crisis. Patience and Pandemic, which is set to be released this month, is a collection of photography, essays and poetry solicited during the summer of 2020 as a way for Anteaters to express themselves during the stay-at-home order.

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Irvine, Calif., Jan. 6, 2021— In the United States, Black, Latino and low-income communities have historically lacked nearby access to pharmacy services. To provide the first record of these “pharmacy deserts” in Los Angeles County, a University of California, Irvine study identified communities where the nearest pharmacy was at least one mile away.

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Irvine, Calif., Jan. 5, 2021 — Scientists at the University of California, Irvine have developed a new deep-learning framework that predicts gene regulation at the single-cell level. Deep learning, a family of machine-learning methods based on artificial neural networks, has revolutionized applications such as image interpretation, natural language processing and autonomous driving.

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Irvine, Calif., Dec. 17, 2020 — Reflectins, the unique structural proteins that give squids and octopuses the ability to change colors and blend in with their surroundings, are thought to have great potential for innovations in areas as diverse as electronics, optics and medicine. Scientists and inventors have been stymied in their attempts to fully utilize the powers of these biomolecules due to their atypical chemical composition and high sensitivity to subtle environmental changes.

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Irvine, Calif., Dec. 17, 2020 —University of California, Irvine health sciences researchers have created a machine-learning model to predict the probability that a COVID-19 patient will need a ventilator or ICU care. The tool is free and available online for any healthcare organization to use. “The goal is to give an earlier alert to clinicians to identify patients who may be vulnerable at the onset,” said Daniel S.

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Irvine, Calif., Dec. 16, 2020 — The University of California, Irvine and the California Department of Corrections and Rehabilitation signed a memorandum of understanding for the design of the first in-prison Bachelor of Arts program offered by the University of California system. The Leveraging Inspiring Futures Through Educational Degrees project will enable incarcerated students at Richard J.

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Irvine, Calif., Dec. 10, 2020 — Although most undocumented students at California’s public universities experience disruptions to their education and well-being due to immigration status concerns, more than two-thirds have a 3.0 or higher GPA, according to a new study led by the University of California, Irvine. The findings are the first to be reported under the UC Collaborative to Promote Immigrant and Student Equity initiative, launched in 2019 and supported by a $270,000 UC Multicampus Research Programs and Initiatives grant.

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Irvine, Calif., Dec. 10, 2020 — Ever see long lines at the pharmacy counter and give up on a medication, or find that the drive is just a little too long? A study by the University of California, Irvine and UC San Diego found that patients using an automated kiosk in their workplace had better prescription pickup rates without sacrificing instruction from pharmacists.

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Irvine, Calif., Dec. 9, 2020 — Researchers in the Henry Samueli School of Engineering at the University of California, Irvine announced promising results in the development of a noninvasive at-home antigen test to detect the spike of SARS-CoV-2 proteins in saliva. The team, led by Michelle Khine, professor of biomedical engineering, posted their findings on the preprint server medRxiv.

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Irvine, Calif., Dec. 8, 2020 — A new class of epidemiological models based on alternative thinking about how contagions propagate, particularly in the early phases of a pandemic, provide a blueprint for more accurate epidemic modeling and improved disease spread predictions and responses, according to a study published recently in Scientific Reports by researchers at the University of California, Irvine and other institutions.

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Irvine, Calif., Dec. 8, 2020 — University of California, Irvine public health experts are providing consulting services to Pacific Symphony to enable the Orange County ensemble to once again play music together – which hasn’t happened since early March because of the coronavirus pandemic. In the past months, Pacific Symphony has held online events – including virtual concerts, living room concerts on video, internet interview programs, and KCET and PBS SoCal’s “Southland Sessions Presents Pacific Symphony” series – featuring offerings from the orchestra’s archival vaults.

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Irvine, Calif., Dec. 7, 2020 — Using the same strain of yeast that ferments wine and makes dough rise, a team led by University of California, Irvine and Harvard Medical School researchers has developed an in vitro technology that can rapidly hypermutate antibodies. The new technology generates antibodies faster than animal immune systems and better than current synthetic methods, giving researchers the tools for evolving exceptionally potent agents, including therapeutic candidates that target SARS-CoV-2.

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Irvine, Calif., Dec. 7, 2020 — In 2018, California wildfires caused economic losses of nearly $150 billion, or about 0.7 percent of the gross domestic product of the entire United States that year, and a considerable fraction of those costs affected people far from the fires and even outside of the Golden State. For a study published today in Nature Sustainability, researchers at the University of California, Irvine, China’s Tsinghua University and other institutions combined physical, epidemiological and economic models to gain a more comprehensive understanding of the impact of the blazes.

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Irvine, Calif., Dec. 1, 2020 — The coming of winter means cooler temperatures, shorter days and flu shots. While no one looks forward to a vaccination, a study led by the University of California, Irvine, has found that either a sincere smile or a grimace can reduce the pain of a needle injection by as much as 40 percent. A genuine, or Duchenne, smile – one that elevates the corners of the mouth and creates crow’s feet around the eyes – can also significantly blunt the stressful, needle-related physiological response by lowering the heart rate.

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Long successful at the University of California, Irvine, Mahtab Jafari’s Life 101 course will be available across the 10 UC campuses during the upcoming winter quarter. The class teaches healthy lifestyle choices, promotes students’ well-being, and helps them to recognize and manage their stress.

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Irvine, Calif., Nov. 3, 2020 — Employing a strategy known as “population modification,” which involves using a CRISPR-Cas9 gene drive system to introduce genes preventing parasite transmission into mosquito chromosomes, University of California researchers have made a major advance in the use of genetic technologies to control the transmission of malaria parasites.

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Irvine, Calif., Oct. 29, 2020 — Identification along the liberal/conservative spectrum may last a lifetime, but cognitive decline distorts our political choices, according to the first-of-its-kind study led by the University of California, Irvine. For those who are cognitively impaired, identifying as being liberal or conservative loses its relationship to their political decision-making.

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Irvine, Calif., Oct. 28, 2020 — Testing a representative sample of Orange County residents for a wide range of coronavirus antibodies, University of California, Irvine researchers found that 11.5 percent of them have antibodies for COVID-19, in contrast to previous estimates of less than 2 percent. Latino and low-income residents had the highest prevalence of SARS-CoV-02 antibodies with rates of 17 percent and 15 percent, respectively.

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Irvine, Calif., Oct. 27, 2020 – Treating cancer without debilitating side effects has long been the holy grail of oncologists, and researchers at the University of California, Irvine and Switzerland’s Lausanne University Hospital may have found it. Charles Limoli, professor of radiation oncology at UCI, and Marie-Catherine Vozenin, associate professor of radiation oncology at the Swiss facility, used an ultra-high dose rate of radiation therapy to eliminate brain tumors in mice, bypassing key side effects usually caused by cranial irradiation.

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Kristen M. Kelly, MD, has been appointed chair for the University of California, Irvine School of Medicine Department of Dermatology, effective September 6, 2020.

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Irvine, Calif., Oct. 22, 2020 — University of California, Irvine biomedical engineer Kyriacos A. Athanasiou has been elected to the National Academy of Medicine, one of the highest distinctions awarded to professionals in the medical sciences, healthcare and public health. He is one of 90 new U.S.-based members announced this week, along with 10 new international members.

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The Alzheimer’s Biomarkers Consortium – Down Syndrome (ABC-DS), a multi-institution research team, co-led by members from the University of California, Irvine, has been awarded an unprecedented five-year, $109 million grant by the National Institutes of Health (NIH), to expand research on the biomarkers of Alzheimer’s disease in adults with Down syndrome.

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Irvine, Calif., Oct. 22, 2020 — Millions of adults in the U.S. join online support groups to help them attain health goals, ranging from weight loss to smoking cessation. In their quest to make connections, members have a tendency to hide demographic differences, concerned about poor social integration that will weaken interpersonal ties.

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Following a national search, the University of California, Irvine School of Medicine and CHOC Children’s have jointly announced that Coleen Cunningham, MD, a renowned professor of pediatrics and pathology from Duke University, has accepted a dual appointment position as both the chair for the UCI Department of Pediatrics and as senior vice president and pediatrician-in-chief for CHOC Children’s.

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Irvine, Calif., Oct. 21, 2020 – With one of the more awe-inspiring names in the animal kingdom, the diabolical ironclad beetle is one formidable insect. Birds, lizards and rodents frequently try to make a meal of it but seldom succeed. Run over it with a car, and the critter lives on. The beetle’s survival depends on two key factors: its ability to convincingly play dead and an exoskeleton that’s one of the toughest, most crush-resistant structures known to exist in the biological world.

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A breakthrough study, led by researchers from the University of California, Irvine, results in the restoration of retinal and visual functions of mice models suffering from inherited retinal disease.

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An international team of climate experts, including Earth system scientists at the University of California, Irvine, today released an assessment of carbon dioxide emissions by industry, transportation and other sectors from January through June, showing that this year’s pandemic lockdowns resulted in a 9 percent decline from 2019 levels.

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Irvine, Calif., Oct. 8, 2020­ – An international team of researchers – including Earth system scientists at the University of California, Irvine – recently completed the most thorough review yet of nitrous oxide from emission to destruction in the planet’s atmosphere. In addition to confirming that the 20 percent increase in the amount of the greenhouse gas since the start of the Industrial Revolution can be totally attributed to humans, the team expressed doubt about the ability to reduce emissions or mitigate their future impacts.

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N-acetylglucosamine, a simple sugar found in human breast milk and sold as an over-the-counter dietary supplement in the United States, promotes myelin repair in mouse models and correlates with myelination levels in multiple sclerosis patients according to a new University of California, Irvine-led study.

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Irvine, Calif., Oct. 7, 2020 – Electrical engineers, computer scientists and biomedical engineers at the University of California, Irvine have created a new lab-on-a-chip that can help study tumor heterogeneity to reduce resistance to cancer therapies. In a paper published today in Advanced Biosystems, the researchers describe how they combined artificial intelligence, microfluidics and nanoparticle inkjet printing in a device that enables the examination and differentiation of cancers and healthy tissues at the single-cell level.

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Irvine, Calif., Oct. 6, 2020 — University of California, Irvine biomedical engineer Chang Liu is the recipient of one of nine Director’s Transformative Research Awards this year from the National Institutes of Health under its High-Risk, High-Reward Research Program, the agency announced today. Liu’s five-year, $8.4 million grant will support a project to develop a system for making antibody generation a routine and widely accessible process.

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Irvine, Calif., Oct. 1, 2020 — Uneven population distribution can significantly impact the severity and timing of COVID-19 infections within a city or county, leading individual communities to have vastly different experiences with the pandemic, according to a recent study led by the University of California, Irvine. Findings published in Proceedings of the National Academy of Sciences show that the heterogeneous spatial features of interpersonal connections may produce dramatic local variations in exposures to those with the illness.

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In a new study, published in Current Biology, researchers from the University of California, Irvine School of Medicine reveal how subanesthetic ketamine, which is used for pain management and as an antidepressant in humans, is effective in treating adult amblyopia, a brain disorder commonly known as “lazy eye.”

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Early results of an experimental vaping study have shown significant lung injury from E-cigarette (eC) devices with nickel-chromium alloy heating elements. The findings were consistent, with or without the use of nicotine, vitamin E oil or tetrahydrocannabinol (THC), which have previously been thought to contribute to the life-threatening respiratory problem.

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Irvine, Calif., Sept. 28, 2020 — The green streak continues! Sierra magazine has named the University of California, Irvine No. 1 overall in its annual “Cool Schools” ranking of sustainability leaders among U.S. and Canadian universities and colleges, marking the fourth time in the last seven years that UCI has topped the widely acclaimed list.

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In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).

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Irvine, Calif., Sept. 18, 2020 – Experiencing multiple stressors triggered by the COVID-19 pandemic – such as unemployment – and COVID-19-related media consumption are directly linked to rising acute stress and depressive symptoms across the U.S., according to a groundbreaking University of California, Irvine study. The report appears in Science Advances, published by the American Association for the Advancement of Science.