Investigators at Cedars-Sinai have uncovered a new pathway that helps explain how consuming too much alcohol causes damage to the liver, specifically mitochondrial dysfunction in alcohol-associated liver disease. The discovery can also help lead to a new treatment approach for people suffering from the disease.
A new collection of scientific articles shines a light on the differences between men and women when it comes to heart health. Experts from the Smidt Heart Institute at Cedars-Sinai led the project, which resulted in an anthology of 14 scientific articles that review the past decade of research on women’s cardiovascular health.
Cancer treatments save lives. They also might cause heart damage in the process. Cedars-Sinai research scientist Arun Sharma, PhD, wants to be able to predict when this might happen, and is creating models of the human heart by using stem cells derived from blood. The goal is to better personalize cancer treatments.
This year marks the fourth anniversary of the affiliation between Cedars-Sinai and Torrance Memorial Medical Center, a partnership forged to bring greater coordination of leading-edge healthcare and services to patients throughout greater Los Angeles.
People in love often say two hearts beat as one, and the hearts of Tom and Therese Mazzei are definitely in sync. When 59-year-old Tom Mazzei traveled from Guam to the Smidt Heart Institute at Cedars-Sinai for treatment, Therese Mazzei, his wife of more than 30 years, accompanied him and found herself being examined for her own heart symptoms.
A new cloud-based data resource co-developed by scientists at Cedars-Sinai provides the research community with a comprehensive set of tools to help identify new subtypes of amyotrophic lateral sclerosis (ALS), a fatal neurological disorder.
As we come up on the two-year anniversary of the COVID-19 pandemic, nerves are fraying, stress levels are rising, and frustration is mounting everywhere. Healthcare workers say they often bear the brunt of people's anger, especially as the latest surge fills hospitals and doctors' offices once again.
Amid the uncertainty of the ongoing COVID-19 pandemic, the Cedars-Sinai Comprehensive Transplant Center and Smidt Heart Institute together completed 573 solid organ transplants in 2021, surpassing 2020’s count of 529 and achieving a new record for the medical center.
Cardiothoracic surgeons in the Smidt Heart Institute at Cedars-Sinai recently performed a groundbreaking robotic-assisted lung transplant.
Many people have questions about a range of new COVID-19 medications that recently became available to outpatients. Rita Shane, PharmD, vice president of Pharmacy Services and chief pharmacy officer at Cedars-Sinai, is available to comment on key points about these therapies.
Throughout the month of February—American Heart Month—the Cedars-Sinai Newsroom will highlight new research, heart-health recommendations and clinical and surgical advances. Experts from the Smidt Heart Institute at Cedars-Sinai, home to California’s top heart and heart surgery programs, are available to address these timely heart-related topics.
The number of people hospitalized for a hypertensive crisis—when blood pressure increases so much it can cause a heart attack, stroke or other sudden cardiovascular event—more than doubled from 2002 to 2014, according to Cedars-Sinai investigators.
A Smidt Heart Institute analysis of lung transplantations performed nationally shows significant help for patients with severe, irreversible lung damage from COVID-19.
The Cedars-Sinai Cancer Blood & Marrow Transplant Program’s one-year patient survival rate exceeded expectations compared to transplant centers in the U.S. whose similar patients underwent allogeneic transplants, according to a national report that tracks those outcomes.
Following Medicare’s decision today about paying for a new Alzheimer’s disease treatment only in limited circumstances, Zaldy Tan, MD, MPH, a highly respected memory and geriatric medicine specialist at Cedars-Sinai, is available to comment.
As the highly contagious omicron variant surges COVID-19 cases to record highs, some are wondering if they should intentionally get the virus in the hope of developing immunity.
As 2022 gets underway, experts in the Cedars-Sinai Departments of Neurology and Neurosurgery are monitoring new Alzheimer’s treatments, while also advancing Cedars-Sinai-led research in noninvasive diagnostic tools for the disease.
First on the list: Get vaccinated and get a booster shot if you qualify.
The secret to producing large batches of stem cells more efficiently may lie in the near-zero gravity conditions of space. Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to lifesaving advances on Earth by facilitating the rapid mass production of stem cells.
Infection with the virus that causes COVID-19 can trigger an immune response that lasts well beyond the initial infection and recovery—even among people who had mild symptoms or no symptoms at all, according to Cedars-Sinai investigators.
Cedars-Sinai scientists have revealed the origins of a common ovarian cancer by modeling fallopian tube tissues, allowing them to characterize how a genetic mutation puts women at high risk for this cancer. The created tissues, known as organoids, hold potential for predicting which individuals will develop ovarian cancer years or even decades in advance, allowing for early detection and prevention strategies.
On a recent Saturday, Gerald Freeny got a sneak peek at a few of this year’s Rose Parade floats being decorated by volunteers at a warehouse in Irwindale, California. The behind-the-scenes look captivates many, but it isn’t new to Freeny. He comes here, year after year, as part of his role as a member of the Tournament of Roses Association.
Cedars-Sinai has named Ophir Klein, MD, PhD, an internationally recognized innovator in pediatrics and genetics, as the inaugural executive director of Cedars-Sinai Guerin Children's and the David and Meredith Kaplan Distinguished Chair in Children's Health.
Zahn, a professor of pediatrics and the director of the Guerin Family Congenital Heart Program in the Smidt Heart Institute, was the principal investigator for the multicenter clinical trial which led to the FDA's approval today. He says the new device will allow interventional cardiologists to treat more patients.
Cedars-Sinai has named Ophir Klein, MD, PhD, an internationally recognized innovator in pediatrics and genetics, as the inaugural executive director of Cedars-Sinai Guerin Children's and the David and Meredith Kaplan Distinguished Chair in Children's Health.
Cedars-Sinai is gathering pediatricians, parents and community members to address important questions about vaccinating children 5-11 years old against COVID-19. The free virtual event, “The Open House: FAQs on COVID-19 Vaccines for Ages 5-11,” will take place from 5-6 p.m. Wednesday, Dec. 15, on Zoom. The conversation will be recorded and available for viewing by clicking here.
Propelled by a historic $100 million gift, Cedars-Sinai is advancing an ambitious vision for children's healthcare to fill a critical gap in care for young patients in Los Angeles and beyond.
Investigators at Cedars-Sinai have identified growth hormone in the colon that increases as the colon ages—a discovery that can help guide the development of a new anti-aging therapy.
As the first cases of flu are reported in Los Angeles this season, public health experts are urging anyone who isn't already vaccinated to get the flu shot. It's the best protection against the flu, which could pummel the U.S. this winter after nearly disappearing last year.
Older women are among the most susceptible to developing UTIs, an infection of the bladder and urethra that causes urinary urgency and pain. UTIs also can cause delirium in older people, resulting in a sharp decline in mental abilities that triggers disoriented thinking.
Patients whose immune systems are weakened due to cancer, organ or bone marrow transplants, chronic diseases, or the medications used to treat these conditions may feel like they have enough on their plates without worrying about whether and when they should take an additional dose of COVID-19 vaccine and a flu shot.
You can't miss Cedars-Sinai's newest helpers: identical twin robots named Moxi.
This holiday season, millions of people will be celebrating with family and friends, perhaps for the first time in two years. While good cheer may fill the air, danger could be lurking just beyond the door to the kitchen or dining room.
Cedars-Sinai physicians who have been on the front lines in the battle against COVID-19 in the community are also doing their part at home by getting their children vaccinated against the virus.
Scientists from Cedars-Sinai are gearing up to send stem cells into space to test whether it is possible to produce large batches in zero gravity for use in treating a variety of diseases back on Earth.
Four months ago, Judy Kronenfeld, PhD, was about to learn whether a suspicious mass in her left lung was cancerous. She underwent two minimally invasive surgical procedures and had a cancer diagnosis, staging and surgery behind her in a matter of hours, not days or weeks.
A new application being used in the Cedars-Sinai Neonatal Intensive Care Unit is going a long way towards easing the anxiety of parents with newborns in the NICU.
Experts from the Smidt Heart Institute, home to California’s top cardiology and heart surgery program, will highlight an array of innovative research, clinical trial data and breakthrough topics during the American Heart Association Scientific Sessions 2021, taking place virtually Nov. 13-15.
Children who have spent most of the COVID-19 pandemic at home and only recently resumed some in-person learning at school might not feel quite ready for the many gatherings with friends and family as the holiday season approaches. But while kids could be out of practice reading facial expressions, sharing toys or taking turns, Jane Tavyev, MD, director of the Division of Pediatric Neurology at Cedars-Sinai, said there are things parents can do to help.
Cedars-Sinai's COVID-19 vaccine drive-thru is now open to children 5 and older, following the U.S. Food and Drug Administration (FDA) authorization and Centers for Disease Control and Prevention (CDC) recommendation that the Pfizer-BioNTech vaccine is safe and effective in children.
Daylight saving time ends this weekend, signaling the beginning of a season filled with holiday celebrations and family traditions for many. But for some, the time change also marks the beginning of seasonal affective disorder (SAD), also known as seasonal depression or winter depression.
Researchers at Cedars-Sinai found that patients with inflammatory bowel disease (IBD)─whose treatment can weaken the immune system─produced a strong antibody response to COVID-19 vaccination. The study findings have been published in the Annals of Internal Medicine.
California’s attorney general recently approved signature gathering for a proposed ballot initiative that seeks to decriminalize psilocybin, the active ingredient in so-called “magic mushrooms,” and to authorize research into the medical use of the compound.
Researchers from the Smidt Heart Institute have discovered two alarming trends in Takotsubo cardiomyopathy—also known as "broken heart" syndrome—a condition that is often triggered by stress or loss and can lead to long-term heart injury and impaired heart function.
Cedars-Sinai took a firm stance on vaccination this week, releasing a multimedia campaign in support of COVID-19 vaccines and the scientists who developed them.
Smidt Heart Institute researchers have found that taking high doses of fish oil supplements—specifically one gram or more per day—may increase the risk of developing atrial fibrillation, an abnormal heart rhythm disturbance with potentially serious complications. The new study was published today in the peer-reviewed journal of the American Heart Association Circulation.
The flu seemed to vanish in 2020 as safety measures meant to stop the spread of COVID-19 also worked against the influenza virus. But with some precautions lifted amid widespread vaccination, what will it mean for this year's flu season?
For women of a certain age, monthly breast self-exams were—and are—as much a part of their health regimens as eating right and exercising often. Conflicting recommendations about the practice from healthcare providers over the years, however, have left many women of all ages confused and wondering whether they should continue the practice.
Researchers at Cedars-Sinai have found that aging produces significant changes in the microbiome of the human small intestine distinct from those caused by medications or illness burden. The findings have been published in the journal Cell Reports.
Cedars-Sinai is joining a nationwide study to investigate how children's development is impacted by biological and environmental exposures, especially to opioids, marijuana, alcohol and tobacco, before and shortly after birth. The goal is to develop insights that can inform public policy to improve the health of children across the nation.
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