Computed tomographic (CT) colonography may offer patients at increased risk of colorectal cancer an alternative to colonoscopy that is less-invasive, is better-tolerated and has good diagnostic accuracy, according to a study in the June 17 issue of JAMA.
A preliminary study suggests that a therapy for severe sepsis or septic shock that included the use of an antibiotic-based "hemoperfusion" device to remove toxic products of bacteria from the blood in addition to conventional treatment resulted in a reduced risk of death and appeared to improve blood circulation and reduce organ dysfunction, according to a report appearing in the June 17 issue of JAMA.
Contrary to a previous report, an analysis of 14 previous studies does not find an association between a serotonin transporter gene variation, stressful life events, and an increased risk of major depression, according to an article in the June 17 issue of JAMA. The authors did find that the number of stressful life events is associated with depression.
A genetic analysis of data from three studies suggests that genetically elevated levels of lipoprotein(a) are associated with an increased risk of heart attack, according to a study in the June 10 issue of JAMA.
An intervention that includes techniques to reduce the amount of radiation from cardiac computed tomography angiography (scanning used to diagnose coronary artery disease) was associated with decreasing patient exposure to radiation without significantly changing the quality of the images, according to a study in the June 10 issue of JAMA.
An analysis of previous studies indicates that allogeneic stem cell transplantation (SCT) (stem cells from a compatible donor) is associated with significant overall and relapse-free survival benefit among adult patients with intermediate- and poor-risk but not good-risk acute myeloid leukemia in first complete remission, compared with nonallogeneic SCT therapies, according to an article in the June 10 issue of JAMA.
Overweight individuals who ate a low-calorie, low-carbohydrate diet high in plant-based proteins for four weeks lost weight and experienced improvements in blood cholesterol levels and other heart disease risk factors, according to a report in the June 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. A high-carbohydrate, low-fat vegetarian diet also resulted in weight loss but without the additional cardiovascular benefits.
Middle-aged adults who sleep fewer hours appear more likely to have high blood pressure and to experience adverse changes in blood pressure over time, according to a report in the June 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Although alcohol consumption is known to be associated with chronic pancreatitis, new evidence indicates that a threshold of five or more drinks per day is required to significantly raise risk; however, most patients with chronic pancreatitis do not drink this amount, according to a report in the June 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. In addition, smoking is an independent, dose-dependent risk factor.
Adolescents at an increased risk of depression who participated in a group cognitive behavioral intervention significantly reduced their symptoms and episodes of depression compared to teens who received usual care, although this effect was not seen for adolescents with a parent with current depression, according to a study in the June 3 issue of JAMA, a theme issue on child and adolescent health.
Infants born extremely preterm are surviving at a high rate, with about 70 percent of infants born alive between 22 and 26 weeks of gestation in Sweden surviving at least one year, with high rates of interventions being used to improve survival, according to a study in the June 3 issue of JAMA, a theme issue on child and adolescent health.
Research indicates that physical and mental stress in childhood may have life-long adverse health effects and policy initiatives are needed to emphasize the importance of starting health promotion and disease prevention early in life, according to an article in the June 3 issue of JAMA, a theme issue on child and adolescent health
With children having easier access to media and a wider variety of content, the possible negative influence on health issues such as sex, drugs, obesity and eating disorders is increased, and warrants monitoring usage and limiting access if necessary, according to a commentary in the June 3 issue of JAMA, a theme issue on child and adolescent health.
The antidepressant citalopram does not appear to reduce the occurrence of repetitive behaviors in children and teens with autism spectrum disorders, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Danish children who move frequently appear to have an increased risk of attempted or completed suicide between ages 11 and 17, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Danish children who move frequently appear to have an increased risk of attempted or completed suicide between ages 11 and 17, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Government warnings about suicidality among children taking antidepressants appear to be associated with unintended and persistent changes in the diagnosis and treatment of depression in children and adults, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
For patients who experience pain and depression, common co-existing conditions, an intervention that included individually tailored antidepressant therapy and a pain self-management program resulted in greater improvement in the symptoms of these conditions than patients who received usual care, according to a study in the May 27 issue of JAMA.
Despite being larger in size and heavier in weight, an analysis of the cardiovascular disease risk factors of about 500 National Football League players finds that overall, they have a similar cardiovascular risk profile compared to the general population. The NFL population was found to have a lower incidence of impaired fasting glucose and similar prevalence of abnormal cholesterol and triglyceride levels as compared to a sample of healthy young-adult men, but have an increased prevalence of high blood pressure, according to a study in the May 27 issue of JAMA.
Hospitalized patients who receive acid-suppressive medications such as a proton-pump inhibitor have a 30 percent increased odds of developing pneumonia while in the hospital, according to a study in the May 27 issue of JAMA.
An estimated 35 percent of U.S. adults age 40 and older have vestibular dysfunction (inner ear balance disorders), and those who do may have a higher risk of falling, according to a report in the May 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Despite reports indicating that placement of retail clinics are determined by physician shortages and higher uninsured populations, these clinics appear to be located in more advantaged neighborhoods, according to a report in the May 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Faculty physicians at academic medical centers may be less likely to experience burnout if they spend at least one day per week on the aspect of their work that is most meaningful to them, according to a report in the May 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Available evidence supports the use of online or other computer-based smoking cessation programs for helping adults quit smoking, according to a meta-analysis of previously published studies appearing in the May 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Use of the medication tamsulosin to treat male urination difficulties within two weeks of cataract surgery is associated with an increased risk of serious postoperative ophthalmic adverse events such as retinal detachment or lost lens, according to a study in the May 20 issue of JAMA.
The injection of bone marrow cells into the heart of patients with chronic myocardial ischemia (reduced blood flow to some areas of the heart) was associated with modest improvements in blood flow and function of the left ventricle, according to a study in the May 20 issue of JAMA.
The increased risk of persons with schizophrenia committing violent crime may be largely mediated by co-existing substance abuse problems, according to a study in the May 20 issue of JAMA.
For patients with persistent insomnia, a combination of cognitive behavior therapy (CBT) and the medication zolpidem for 6 weeks was associated with improvement in sleep, although for a longer treatment period CBT alone was more beneficial, according to a study in the May 20 issue of JAMA.
Persons with higher levels of cardiorespiratory fitness have a lower risk of all-cause death and coronary heart disease and cardiovascular disease compared to persons with lower levels of cardiorespiratory fitness, according to an analysis of previous studies appearing in the May 20 issue of JAMA.
A home-based diet and exercise program reduced the rate of functional decline among older, overweight long-term survivors of colorectal, breast and prostate cancer, according to a study in the May 13 issue of JAMA.
Men with systolic chronic heart failure who have low or high levels of estradiol, a form of the hormone estrogen, have an increased risk of death compared with men with moderate levels of this hormone, according to a study in the May 13 issue of JAMA.
An analysis of previous studies indicates that among patients with peripheral artery disease, aspirin use is associated with a statistically nonsignificant decrease in the risk of a group of combined cardiovascular events (nonfatal heart attack, nonfatal stroke, and cardiovascular death), but is associated with a significant reduction in the risk of one of these events, nonfatal stroke, although the findings may be limited by the lack of a large study population, according to an article in the May 13 issue of JAMA.
Although a large number of children's hospitals have developed or are developing policies regarding organ donation after cardiac death, there is considerable variation among policies, including the criteria for declaring death, according to a study in the May 13 issue of JAMA.
Three types of acupuncture therapy"”an individually tailored program, standard therapy and a simulation involving toothpicks at key acupuncture points"”appear more effective than usual care for chronic low back pain, according to a report in the May 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Exposure to small promotional items from pharmaceutical companies, such as clipboards and notepads, appears to influence medical students' unconscious attitudes toward the marketed product, according to a report in the May 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. Students whose medical school restricts marketing practices had less favorable attitudes toward the product following exposure to the items, while those at a school with no such limitations responded more favorably.
A diet designed to prevent and treat high blood pressure also may be associated with a lower risk of heart failure among women, according to a report in the May 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
The responses of older adults who are asked whether they had a stroke frequently do not agree with diagnoses obtained by magnetic resonance imaging (MRI) of the brain, according to a report posted online today that will appear in the July print issue of Archives of Neurology, one of the JAMA/Archives journals.
Levels of biomarkers in the cerebrospinal fluid of individuals with very mild dementia may be associated with the rate at which their thinking, learning and memory skills decline, according to a report in the May issue of Archives of Neurology, one of the JAMA/Archives journals.
An intervention that provided housing and case management to homeless adults with chronic medical illnesses reduced hospitalizations and emergency department visits, according to a study in the May 6 issue of JAMA.
Certain heart attack patients who experience a rapid, abnormal heart rhythm before or after a coronary artery intervention or stent placement have a significantly higher risk of death within 90 days of the procedure, according to a study in the May 6 issue of JAMA.
Preliminary research suggests that higher than normal levels of the protein albumin in urine is associated with an increased risk for blood clots in the deep veins of the legs or lungs (venous thromboembolism; VTE), according to a study in the May 6 issue of JAMA.
Children who are consistently victimized by peers appear more likely to develop psychotic symptoms in early adolescence, according to a report in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
About half of women whose symptoms of severe premenstrual syndrome are relieved by the antidepressant sertraline appear to experience relapse within six to eight months after stopping medication, according to a report in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals. Women with more severe symptoms and those who took the drug for a shorter period of time may be more likely to relapse.
Toddlers with autism appear more likely to have an enlarged amygdala, a brain area associated with numerous functions, including the processing of faces and emotion, according to a report in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals. In addition, this brain abnormality appears to be associated with the ability to share attention with others, a fundamental ability thought to predict later social and language function in children with autism.
Patients whose implantable cardioverter-defibrillators (ICDs) are implanted by nonelectrophysiologists are at increased risk of complications and are less likely to receive a specific type of ICD when clinically indicated, according to a study in the April 22/29 issue of JAMA.
The proportion of Medicare patients experiencing continuity of care between outpatient and inpatient settings decreased substantially between 1996 and 2006, with decreases occurring in all areas of the country and in all types of hospitals, according to a study in the April 22/29 issue of JAMA.
Contrary to what may be a common perception, researchers found no evidence that the likelihood of kidney transplantation is lower among remote- or rural-dwelling patients treated for kidney failure in the United States, according to a study in the April 22/29 issue of JAMA.
Screening for coronary artery disease in patients with type 2 diabetes did not result in a significant reduction in the rate of heart attacks or cardiac death compared to patients who were not screened, according to a study in the April 15 issue of JAMA, a theme issue on diabetes.
Having hypoglycemic (low blood sugar level) episodes that are severe enough to require hospitalization are associated with a greater risk of dementia for older adults with type 2 diabetes, according to a study in the April 15 issue of JAMA, a theme issue on diabetes.
The majority of patients with type 1 diabetes who underwent a certain type of stem cell transplantation became insulin free, several for more than three years, with good glycemic control, and also increased C-peptide levels, an indirect measure of beta-cell function, according to a study in the April 15 issue of JAMA, a theme issue on diabetes.
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