Latest News from: JAMA - Journal of the American Medical Association

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15-Feb-2007 5:20 PM EST
Injection of “Skin Filler” Material Appears to Stimulate Collagen Production
JAMA - Journal of the American Medical Association

Injections with "dermal fillers" containing hyaluronic acid appear to stimulate production of collagen, a primary protein in the skin, and may partially restore the structure of sun-damaged skin, according to an article in the February issue of Archives of Dermatology, one of the JAMA/Archives journals.

15-Feb-2007 5:30 PM EST
Multiple Low-Energy Plasma Skin Treatments May Help Diminish Facial Wrinkles
JAMA - Journal of the American Medical Association

A study involving eight patients suggests that multiple low-energy treatments with a plasma skin regeneration tool may help to reduce wrinkles and improve facial appearance with minimal healing time, according to an article in the February issue of Archives of Dermatology, one of the JAMA/Archives journals.

15-Feb-2007 5:35 PM EST
Surgeons With Video Game Skill Appear to Perform Better in Simulated Surgery Skills Course
JAMA - Journal of the American Medical Association

In a study involving 12 surgeons and 21 surgical residents, video game skill was correlated with laparoscopic surgery skill as assessed during a simulated surgery skills course, according to a report in the February issue of Archives of Surgery, one of the JAMA/Archives journals.

15-Feb-2007 5:40 PM EST
Blood Marker Helps Predict Prognosis Among Those With Abdominal Infection
JAMA - Journal of the American Medical Association

Monitoring blood levels of a compound known as procalcitonin in patients with peritonitis (a serious intra-abdominal infection) could help identify patients at increased risk of organ failure and death, according to a report in the February issue of Archives of Surgery, one of the JAMA/Archives journals.

15-Feb-2007 7:45 PM EST
Psychiatric and Neurologic Conditions May Underlie Many Cases of Chronic Dizziness
JAMA - Journal of the American Medical Association

Chronic dizziness may have several common causes, including anxiety disorders, migraine, traumatic brain injury and disorders in the part of the nervous system governing involuntary activities, according to a report in the February issue of Archives of Otolaryngology"“Head & Neck Surgery, one of the JAMA/Archives journals.

8-Feb-2007 4:10 PM EST
Optimal Timing for Administration of Platelet-Inhibiting Drugs for Treatment of ACS Patients
JAMA - Journal of the American Medical Association

Clinicians should carefully weigh the risks and benefits of when to administer platelet glycoprotein IIb/IIIa (Gp IIb/IIIa) inhibitors for patients with acute coronary syndromes undergoing invasive treatment, according to a study in the February 14 issue of JAMA.

8-Feb-2007 4:25 PM EST
Reducing Iron Levels in Body Does Not Appear to Decrease Risk of Death, Cardiovascular Events for PAD Patients
JAMA - Journal of the American Medical Association

The reduction of body iron stores through phlebotomy (blood removal) in patients with peripheral artery disease (PAD) does not appear to decrease the risk of death plus nonfatal cardiovascular events, according to a study published in the February 14 issue of JAMA.

8-Feb-2007 4:30 PM EST
New Cardiovascular Risk Prediction Models Developed for Women
JAMA - Journal of the American Medical Association

Researchers have developed a more accurate way to predict the risk of developing cardiovascular disease among women, according to a study in the February 14 issue of JAMA.

8-Feb-2007 6:45 PM EST
Midday Napping (Siesta) Associated With Reduced Risk of Heart-Related Death
JAMA - Journal of the American Medical Association

Among Greek adults, taking regular midday naps is associated with reduced risk of death from heart disease over a six-year period, especially among working men, according to a report in the February 12 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

8-Feb-2007 6:50 PM EST
Disparities in Colon Cancer Screening Remain Among Medicare Patients
JAMA - Journal of the American Medical Association

Although Medicare coverage for colorectal cancer screening has increased, there are still significant disparities in screening practices by ethnicity, sex, age, education and income level, according to a report in the February 12, 2007 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

8-Feb-2007 6:55 PM EST
Characteristics of Patients at Increased Risk for Compulsive Gambling Associated With Taking Parkinson’s Meds
JAMA - Journal of the American Medical Association

Patients with Parkinson's disease who are younger when they develop the condition, have a personality trait known as novelty-seeking or whose personal or family history includes alcohol abuse may be more likely to develop pathological gambling as a side effect of medications used to treat their condition, according to a report in the February issue of Archives of Neurology, one of the JAMA/Archives journals.

8-Feb-2007 7:05 PM EST
Extent of Brain Involvement at Diagnosis May Predict Rate of Later Brain Atrophy in Patients With MS
JAMA - Journal of the American Medical Association

In patients with recently diagnosed multiple sclerosis, the extent of accumulated brain tissue loss and overall lesion load as determined by magnetic resonance imaging (MRI) may predict the rate of cerebral atrophy over the following two years, according to a report in the February issue of Archives of Neurology, one of the JAMA/Archives journals.

1-Feb-2007 6:00 PM EST
Drug Used in Coronary Artery Bypass Graft Surgery May Increase Risk of Death
JAMA - Journal of the American Medical Association

Aprotinin, a drug used for limiting blood loss in patients undergoing cardiac surgery, is associated with an increased risk of death during five years following the surgery, according to a new study in the February 7 issue of JAMA.

1-Feb-2007 6:10 PM EST
Return on Investment for Pediatric Exclusivity Program Varies for Pharmaceutical Companies
JAMA - Journal of the American Medical Association

The economic return for a program designed to encourage drug manufacturers to conduct more pediatric clinical trials by granting extensions of patent protection or marketing exclusivity generates lucrative returns for blockbuster products and produces more modest returns on investment for many others, according to a study in the February 7 issue of JAMA.

1-Feb-2007 6:15 PM EST
Statin Therapy Associated with Regression of Coronary Atherosclerosis with Key Lipid Level Changes
JAMA - Journal of the American Medical Association

An analysis of data from four clinical trials suggests that statin therapy is associated with regression of coronary atherosclerosis when low-density lipoprotein cholesterol (LDL-C or "bad" cholesterol) is substantially reduced and high-density lipoprotein cholesterol (HDL-C or "good" cholesterol) is increased, but it remains to be determined whether this degree of atherosclerosis regression will translate to meaningful reductions in cardiovascular events.

1-Feb-2007 6:20 PM EST
Researchers Identify Five Genetic Variations Associated with Risk of Venous Thrombosis in Women
JAMA - Journal of the American Medical Association

Researchers have identified new genetic variations that may be associated with the risk of developing nonfatal venous thrombosis in postmenopausal women, according to a study in the February 7 issue of JAMA.

1-Feb-2007 4:00 PM EST
Severely Mentally Ill Have Increased Risk of Death from Cardiovascular Disease
JAMA - Journal of the American Medical Association

A large British study indicates that individuals with severe mental illnesses are significantly more likely to die from coronary heart disease and stroke, but not cancer, than those without mental illnesses, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

1-Feb-2007 4:00 PM EST
Symptoms of Depression Linked to Early Stages of Artery Disease
JAMA - Journal of the American Medical Association

Depressive symptoms"”especially physical signs, such as fatigue and loss of appetite"”may be associated with thickening arteries, which may reflect an early sign of coronary artery disease, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

1-Feb-2007 4:15 PM EST
Loneliness Associated With Increased Risk of Alzheimer's Disease
JAMA - Journal of the American Medical Association

Lonely individuals may be twice as likely to develop the type of dementia linked to Alzheimer's disease in late life as those who are not lonely, according to an article in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

18-Jan-2007 4:35 PM EST
Medication Effective in Treating Depression in Patients With Coronary Artery Disease
JAMA - Journal of the American Medical Association

Patients with symptoms of depression who have coronary artery disease showed improvement of their symptoms with use of the drug citalopram, but adding interpersonal psychotherapy did not appear to be of benefit, according to a study in the January 24/31 issue of JAMA.

18-Jan-2007 4:40 PM EST
Among Older Adults, Men Have Similar Refracture Risk as Women
JAMA - Journal of the American Medical Association

After sustaining an initial low-trauma fracture, older men and women have a similar and substantial risk of subsequent fracture, according to a study in the January 24/31 issue of JAMA.

18-Jan-2007 4:45 PM EST
Tuberculosis Intervention Program Improves Patient Outcomes
JAMA - Journal of the American Medical Association

Patients with tuberculosis in the West African country of Senegal who participated in an intervention program that included improved communication with health personnel and community involvement had higher cure and treatment completion rates, according to a study in the January 24/31 issue of JAMA.

18-Jan-2007 7:25 PM EST
Rapid Flu Testing Is Associated With Decreased Antibiotic Use in Hospitalized Adults
JAMA - Journal of the American Medical Association

Rapid influenza testing is associated with reductions in the use of antibiotics in hospitalized adults, according to a report posted online today that will appear in the February 26, 2007, print issue of Archives of Internal Medicine, one of the JAMA/Archives journals. The study was posted online today because of its importance to public health.

18-Jan-2007 7:35 PM EST
Daily Use of Antidepressants Associated With Increased Risk of Fracture in Older Adults
JAMA - Journal of the American Medical Association

Daily use of the antidepressant medications known as selective serotonin reuptake inhibitors (SSRIs) by adults 50 years and older is associated with a doubled risk of some fractures, according to a report in the January 22, 2007 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

18-Jan-2007 7:40 PM EST
Repeat Bone Mineral Density Scans Do Not Appear Helpful for Predicting Fractures in Most Older Women
JAMA - Journal of the American Medical Association

Repeating a bone mineral density (BMD) scan up to eight years after an initial BMD appears to provide little additional benefit for predicting fractures among older postmenopausal women, according to a report in the January 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

18-Jan-2007 7:40 PM EST
Selenium Supplements May Contribute to Reduced HIV Viral Load
JAMA - Journal of the American Medical Association

Taking daily selenium supplements appears to increase the level of the essential mineral in the blood and may suppress the progression of viral load in patients with HIV infection, according to an article in the January 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

18-Jan-2007 7:50 PM EST
Hypertension Control Appears Better in U.S. Than in Western Europe
JAMA - Journal of the American Medical Association

Individuals with diagnosed hypertension in the United States appear to have lower blood pressure readings and better hypertension control than patients in five Western European countries, according to a report in the January 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

18-Jan-2007 7:55 PM EST
Psychosocial Factors Associated with Higher Levels of Inflammatory Markers
JAMA - Journal of the American Medical Association

Psychosocial factors, such as cynical distrust, chronic stress and depression, may be associated with higher levels of inflammatory markers measured in the blood, which in turn are related to an increased risk for cardiovascular disease, according to a report in the January 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

11-Jan-2007 7:05 PM EST
Chemotherapy Appears to Delay Cancer Recurrence Following Surgery for Pancreatic Cancer
JAMA - Journal of the American Medical Association

Use of the drug gemcitabine for chemotherapy significantly delays the recurrence of cancer, compared to no chemotherapy, for patients following pancreatic cancer surgery, according to a study in the January 17 issue of JAMA.

11-Jan-2007 7:10 PM EST
South Asians Have Higher Levels of Heart Attack Risk Factors at Younger Ages
JAMA - Journal of the American Medical Association

People who are native to South Asia experience heart attacks at a younger age because of greater levels of heart attack risk factors such as smoking and diabetes at a younger age, according to a study in the January 17 issue of JAMA.

11-Jan-2007 7:15 PM EST
Statistical Method Used Influences Results of Observational Studies
JAMA - Journal of the American Medical Association

A study comparing different statistical methods used to remove the effects of selection bias in observational studies finds that results may vary and caution may be warranted when interpreting findings of studies using certain methods, according to an article in the January 17 issue of JAMA.

4-Jan-2007 5:00 PM EST
Elevated Level of Certain Cardiac Biomarker May Help Predict Risk of Cardiovascular Events
JAMA - Journal of the American Medical Association

A blood test for patients with coronary heart disease could help predict their risk for subsequent cardiovascular events or death, according to a study in the January 10 issue of JAMA.

4-Jan-2007 5:10 PM EST
Improved Adherence to Certain Medications Associated With Longer Survival Following Heart Attack
JAMA - Journal of the American Medical Association

New research suggests that the pharmacological effects of taking medications such as statins and beta-blockers as prescribed following a heart attack is associated with living longer, according to a study in the January 10 issue of JAMA.

4-Jan-2007 5:25 PM EST
Genetic Factors Associated With Head and Neck Cancer
JAMA - Journal of the American Medical Association

Preliminary research indicates that several specific genetic alterations are associated with the development of smoking-related head and neck skin cancers, according to a report in the January 10 issue of JAMA.

4-Jan-2007 4:35 PM EST
Caregiving for Those at End of Life Rewarding Despite Challenges
JAMA - Journal of the American Medical Association

Family or friends served as informal caregivers to almost three-quarters of disabled older adults living in the community during their final year of life, according to an article in the January 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

4-Jan-2007 4:40 PM EST
High Hospital House Staff Workload Associated with Worse Patient Outcomes
JAMA - Journal of the American Medical Association

A heavier workload for hospital residents on patient admission days was associated with increased length of hospital stay, total costs and risk of inpatient death, according to a report in the January 8 issue of the Archives of Internal Medicine, one of the JAMA/Archives journals.

4-Jan-2007 4:50 PM EST
Higher Folate Levels Linked to Reduced Risk for Alzheimer's Disease
JAMA - Journal of the American Medical Association

Individuals who take in higher levels of the nutrient folate through both diet and supplements may have a reduced risk of developing Alzheimer's disease, according to a report in the January issue of Archives of Neurology, one of the JAMA/Archives journals.

27-Dec-2006 4:10 PM EST
Med Doesn't Appear to Offer Benefit for Certain Heart Attack Patients Undergoing Angioplasty or Stent Procedure
JAMA - Journal of the American Medical Association

Use of the drug pexelizumab immediately before and for 24 hours after stent placement or angioplasty for certain heart attack patients did not have any significant treatment effect compared to placebo, according to a study in the January 3 issue of JAMA. The medication had shown promise in preliminary studies.

27-Dec-2006 4:15 PM EST
Clinical Guidelines Help Identify Which Children at Risk of Bacterial Meningitis
JAMA - Journal of the American Medical Association

A set of guidelines have been developed that can help predict the risk of bacterial meningitis for children with cerebrospinal fluid pleocytosis (presence of greater number of white blood cells than normal), reducing unnecessary hospitalizations and antibiotics, according to a study in the January 3 issue of JAMA.

27-Dec-2006 4:20 PM EST
Most Hospital Performance Measures for Heart Failure Not Linked to Improved Patient Outcomes
JAMA - Journal of the American Medical Association

Four of five hospital performance measures for heart failure do not appear to accurately reflect the quality of care provided, according to a study in the January 3 issue of JAMA.

28-Dec-2006 4:00 PM EST
PTSD May Increase Heart Disease Risk in Older Men
JAMA - Journal of the American Medical Association

A higher level of symptoms of posttraumatic stress disorder may increase the risk of coronary heart disease in older men, according to a report in the January issue of the Archives of General Psychiatry, one of the JAMA/Archives journals.

28-Dec-2006 4:00 PM EST
Patients With PTSD Experience Less Pain Sensitivity; May Be Related to Altered Processing
JAMA - Journal of the American Medical Association

Patients with posttraumatic stress disorder show reduced pain sensitivity, a pattern that may be related to altered pain processing in the brain, according to a report in the January issue of the Archives of General Psychiatry, one of the JAMA/Archives journals.

28-Dec-2006 4:00 PM EST
Child Abuse and Neglect Associated With Increased Risk of Depression Among Young Adults
JAMA - Journal of the American Medical Association

People who were abused and neglected during childhood have a higher risk of major depression when they become young adults, according to a report in the January issue of the Archives of General Psychiatry, one of the JAMA/Archives journals.

21-Dec-2006 4:00 PM EST
Women May Be Able to 'Take Break' From Osteoporosis Drug Without Losing Benefit
JAMA - Journal of the American Medical Association

Most postmenopausal women who took the osteoporosis drug alendronate for 5 years and then stopped did not have an increased risk for nonvertebral fractures in the next 5 years, suggesting the medication has a lasting effect, according to a study in the December 27 issue of JAMA.

21-Dec-2006 4:00 PM EST
Incidence of Stroke Decreases Over Last 50 Years
JAMA - Journal of the American Medical Association

The incidence of stroke in the U.S. over the past 50 years has declined, although the severity of stroke has not, according to a study in the December 27 issue of JAMA.

21-Dec-2006 4:00 PM EST
Acid Suppression Medication Linked With Increased Risk of Hip Fracture
JAMA - Journal of the American Medical Association

Use of the drugs proton pump inhibitors (PPIs) for the treatment of acid-related diseases such as gastro esophageal reflux disease (GERD) is associated with a greater risk of hip fracture, according to a study in the December 27 issue of JAMA.

14-Dec-2006 4:40 PM EST
Cognitive Training for Older Adults May Help Slow Decline of Daily Functioning Abilities
JAMA - Journal of the American Medical Association

Older adults who received cognitive training reported improved cognitive function for up to 5 years afterwards and less decline in the ability to perform daily activities as compared to those who did not receive the training, according to a study in the December 20 issue of JAMA.

14-Dec-2006 5:00 PM EST
More Patients Being Diagnosed at Earlier Stage of Colon Cancer Since Expansion of Medicare Coverage
JAMA - Journal of the American Medical Association

Since Medicare raised the amount it will reimburse for colon cancer screening in 1998, there has been an increase in use of colonoscopies by Medicare beneficiaries, and a rise in the proportion of patients being diagnosed with colon cancer at an early stage, according to a study in the December 20 issue of JAMA.

14-Dec-2006 5:15 PM EST
Kidney Transplantation Linked With Increased Risk of Various Cancers
JAMA - Journal of the American Medical Association

Following kidney transplantation, some recipients may face a 3-fold increased risk of certain cancer types, according to a study in the December 20 issue of JAMA.

14-Dec-2006 5:20 PM EST
Higher Levels of Vitamin D in the Blood May Lower Risk of Multiple Sclerosis
JAMA - Journal of the American Medical Association

New research suggests that having higher circulating levels of vitamin D is associated with a reduced risk for multiple sclerosis, although this relationship was not seen for black and Hispanic individuals, according to a study in the December 20 issue of JAMA.



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