An emotion regulation strategy known as cognitive reappraisal helped reduce the typically heightened and habitual attention to drug-related cues and contexts in cocaine-addicted individuals, a study by Mount Sinai researchers has found.
Mount Sinai researchers create a machine learning model to determine COVID-19 patients most at risk for treatment requiring dialysis or critical illness leading to death.
Women who were highly exposed to ultra-fine particles in air pollution during their pregnancy were more likely to have children who developed asthma, according to a study published in the American Journal of Respiratory and Critical Care Medicine in May. This is the first time asthma has been linked with prenatal exposure to this type of air pollution, which is named for its tiny size and which is not regulated or routinely monitored in the United States.
An oral medication called upadacitinib yielded rapid and significant improvements in patients with moderate to severe atopic dermatitis (AD), also known as eczema, in phase 3 clinical trials, Mount Sinai researchers reported today in The Lancet online.
The virtual Annual Meeting of the American Society of Clinical Oncology (ASCO), the largest medical meeting on the latest cancer research findings, will include several presentations by investigators from The Tisch Cancer Institute at Mount Sinai. Mount Sinai physician scientists will present leading research studies, including oral presentations on bladder cancer and disparities in cancer.
International consortium of leading psychiatric genetics scientists studied thousands of DNA sequences, more than doubling the number of regions previously identified
William Whang, MD, Associate Professor of Medicine (Cardiology), and Gilbert Tang, MD, MSc, MBA, Associate Professor of Cardiovascular Surgery at the Icahn School of Medicine at Mount Sinai, are receiving the 2021 Simon Dack Awards for their exceptional contributions to the Journal of the American College of Cardiology (JACC).
The investigational drug evinacumab reduced triglycerides in patients with severe hypertriglyceridemia (sHTG) and a history of hospitalizations for acute pancreatitis in a phase 2 global study led by Mount Sinai
Artificial food colorants can cause disease when the immune system has become dysregulated, Icahn School of Medicine at Mount Sinai researchers report. The study, published in Cell Metabolism in May, was the first to show this phenomenon.
Virologist Gustavo Palacios, PhD, is joining the Icahn School of Medicine at Mount Sinai from the United States Army Medical Research Institute of Infectious Diseases (USAMRIID), where he led the application and development of molecular epidemiology to advance the field of biopreparedness. Dr. Palacios will strengthen existing research collaborations between Icahn Mount Sinai and the United States Army-Department of Defense (DoD), laying a foundation for joint research initiatives to protect national and global public health.
Researchers have finally cracked the code of a bewildering pediatric disease that sets off a characteristic cytokine storm—a harmful immune system overaction resembling one that arises in COVID-19 cases—and can lead to catastrophic multisystem organ failure or neurodegeneration. Their study, which identifies the cause of the cytokine storm and possible treatments, was published in Nature Medicine in May.
Recognizing that burnout and stress have a negative impact on the personal and professional lives of faculty, staff, and trainees, as well as the quality of care that patients receive, the Mount Sinai Department of Surgery has launched the Stress Intervention Tools (SIT) program to help surgeons work through their emotions, reduce their anxiety, and manage crises.
In honor of Nurses Week, Thursday, May 6, through Wednesday, May 12, Mount Sinai Health System will host several celebratory and commemorative events to celebrate the professionalism, innovation, and resilience of nurses. The events will highlight and showcase the great work of Mount Sinai nurses during this pandemic and beyond, underscoring the importance and prominence of their role in health care.
Oula, a modern maternity center combining the best of obstetrics and midwifery care, today announced its partnership with Mount Sinai West, one of New York’s well-respected hospitals, located on the west side of Manhattan. Through this partnership, Oula patients — who receive prenatal, birth, and postpartum care via the company’s collaborative medical team, Brooklyn clinic, and remote care platform — will now be able to deliver their babies at Mount Sinai. They will receive full access to hospital resources and specialists they may need, all while remaining under the care of Oula’s medical team for non-surgical births.
A combination of remdesivir, a drug currently approved in the United States for treating COVID-19 patients, and repurposed drugs for hepatitis C virus (HCV) was 10 times more effective at inhibiting SARS-CoV-2, the virus that causes COVID-19.
Patients hospitalized with COVID-19 may be at risk of developing heart failure even if they do not have a previous history of heart disease or cardiovascular risk factors, a new Mount Sinai study shows.
With highly trained specialists skilled in caring for different types of melanoma, patients at the Waldman Melanoma and Skin Cancer Center will have access to the newest diagnostics and therapies such as Canfield Vectra180 – a 3D whole body imaging system that captures nearly the entire skin surface in macro quality resolution, and will be able to capture early skin cancer lesions; Nevisense—a safe diagnostic support tool utilizing Electrical Impedence Spectroscopy (EIS) which is applied as a harmless electrical signal to the skin; Vivascope 1500—a non-invasive confocal imaging system which offers a non-invasive way to image the skin to the superficial collagen layers; and innovative technologies which non-invasively collects skin cells through adhesive patches rather than a scalpel to diagnose atypical pigmented lesions (or moles) at high risk for melanoma.
Mount Sinai Researchers Find That Tranexamic Acid, a Blood Clotting Drug Commonly Used for Orthopedic Surgeries, Does Not Increase Complications for High-Risk Patients
The Graduate School of Biomedical Sciences at the Icahn School of Medicine at Mount Sinai will offer a new PhD concentration in Artificial Intelligence and Emerging Technologies in Medicine (AIET) as part of its PhD in Biomedical Sciences program. Hayit Greenspan, PhD and Alan C. Seifert, PhD are the newly appointed AIET Co-Directors. Application will be open from late August through December 1, 2021 for enrollment in the fall of 2022.
Although antibodies induced by SARS-CoV-2 infection are largely protective, they do not completely protect against reinfection in young people, as evidenced through a longitudinal, prospective study of more than 3,000 young, healthy members of the US Marines Corps conducted by researchers at the Icahn School of Medicine at Mount Sinai and the Naval Medical Research Center, published April 15 in The Lancet Respiratory Medicine.
The complex patterns of genetic ancestry uncovered from genomic data in health care systems can provide valuable insights into both genetic and environmental factors underlying many common and rare diseases, according to a team of Mount Sinai researchers.
Major depressive disorder is highly prevalent, with one in five people experiencing an episode at some point in their life, and is almost twice as common in women than in men.
A personalized cancer vaccine developed with the help of a Mount Sinai computational platform raised no safety concerns and showed potential benefit in patients with different cancers, including lung and bladder, that have a high risk of recurrence, according to results from an investigator-initiated phase I clinical trial presented during the virtual American Association for Cancer Research (AACR) Annual Meeting 2021, held April 10-15.
Sets of genes associated with resistance to immunotherapy in patients with metastatic urothelial cancer of the bladder have been identified and validated by researchers at Mount Sinai. In a study published in Clinical Cancer Research, the team uncovered gene signatures representing adaptive immunity and pro-tumorigenic inflammation that were responsible for sensitivity or resistance to immune checkpoint inhibitors, drugs that help the body’s immune system recognize and attack cancerous cells.
Mount Sinai Doctors has opened its first cardiology location in Brooklyn, New York, with a team of highly skilled physicians, nurses, technicians, medical assistants and cardiac services. Mount Sinai Doctors-Brooklyn, Cardiology is 5,000 square feet and located at 1977 Flatbush Avenue, Brooklyn.
Historic case launches Mount Sinai’s Tracheal Transplant Program for treating patients worldwide, including those with severe intubation damage after COVID-19
Mount Sinai researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the virus that causes COVID-19.
Immunotherapy is not only significantly less effective in liver cancer patients who previously had a liver disease called non-alcoholic steatohepatitis (NASH), but actually appears to fuel tumor growth, according to a Mount Sinai study published in Nature in March. NASH affects as many as 40 million people worldwide and is associated with obesity and diabetes.
Mount Sinai researchers have received a grant award to lead a collaborative team of New York institutions in an initiative that addresses disparities in the participation of Black, indigenous, and people of color (BIPOC) in cancer clinical trials.
An epigenetic modification that occurs in a major cell type in the brain’s reward circuitry controls how stress early in life increases susceptibility to additional stress in adulthood, researchers at the Icahn School of Medicine at Mount Sinai have learned.
The Mount Sinai Hospital is the first academic center in the Northeast region to teach Aquablation® therapy—a robotically guided advanced new therapy and minimally invasive procedure used to treat enlarged prostates, a common condition technically known as benign prostatic hyperplasia (BPH). The teaching program is being led by Steven A. Kaplan, MD, Professor of Urology, Icahn School of Medicine at Mount Sinai and Director of the Men's Wellness Program, Mount Sinai Health System.
A single shot of one of the currently authorized COVID-19 vaccines may be sufficient to provide immunity to individuals who have previously been infected by the virus, thus eliminating the need for a second dose and helping to stretch severely limited vaccine supplies, a study from Mount Sinai has found
Mount Sinai Health System announced today that Kantaro Biosciences, LLC, a joint venture with RenalytixAI, has been named to Fast Company’s prestigious annual list of the “World’s Most Innovative Companies” for 2021 and ranked first in the Joint Ventures category.
A low-cost COVID-19 vaccine candidate that could be produced in the United States and worldwide using existing influenza virus manufacturing infrastructure has been developed by researchers at Icahn School of Medicine at Mount Sinai
Overweight children who were exposed to lead in utero and during their first weeks of life have the potential for poorer kidney function in adulthood, according to an Icahn School of Medicine at Mount Sinai study published in Environment International in March.
Researchers from the Icahn School of Medicine at Mount Sinai have identified a drug that works against depression by a completely different mechanism than existing treatments.
Molecules called microRNAs (miRNAs) that are measurable in urine have been identified by researchers at Mount Sinai as predictors of both heart and kidney health in children without disease. The epidemiological study of Mexican children was published in February in the journal Epigenomics.