A University of Iowa study may provide an explanation for why some people get migraine headaches while others do not. The researchers found that too much of a small protein called RAMP1 appears to "turn up the volume" of a nerve cell receptor's response to a neuropeptide thought to cause migraines.
Blood tests for panic disorder and other mental health conditions are potentially around the corner, based on results from a University of Iowa study. In a related study also published the same day, researchers report a potential blood test for nicotine dependency.
Genetic tests using blood samples already are used to diagnose some diseases and even personalize treatment. Now it is possible to develop similar tests that reveal a person's potential to become dependent on nicotine or marijuana or have antisocial personality disorder.
University of Iowa researchers and collaborators have identified new genetic mutations that likely cause the common form of cleft lip and palate. The results could eventually help clinicians predict a family's risk of having more children with the condition.
Antidepressant treatment appears to help stroke survivors with the kind of complex mental abilities often referred to as "thinking outside the box." The antidepressants' effects on study participants' abilities were independent of any changes in depression.
A new tool can help public health officials better predict when a bird flu pandemic will strike and plan ways to stem its effects. A collaboration of the University of Iowa Tippie College of Business and Carver College of Medicine, the Iowa Health Prediction Market has launched the Avian Flu Market
Men who get a "false-positive" prostate cancer result -- an abnormal screening test followed by a biopsy indicating no cancer -- appear more likely to worry about subsequent risk of cancer and report more problems with sexual function compared to men with normal screening results.
University of Iowa physicians and engineers have begun "Project 3000," which aims to identify all 3,000 U.S. men, women and children who have Leber's Congenital Amaurosis, a sight-robbing disease.
An international team of cancer specialists and imaging experts has developed standardized guidelines for assessing lymphoma response to treatment. The guidelines will provide clinicians with uniform criteria to compare and interpret clinical trials of lymphoma treatments and should facilitate the development of new therapies.
Adults living with children eat more saturated fat -- the equivalent of nearly an entire small frozen pepperoni pizza each week -- than do adults who do not live with children, according to a University of Iowa and University of Michigan Health System study.
How a potentially deadly bacterium that could be used as a bioterrorist tool eludes being killed by the human immune system is now better understood, researchers report in the December issue of the Journal of Leukocyte Biology.
Pregnant women can minimize their risk of becoming infected with lymphocytic choriomeningitis virus (LCMV), an infectious agent carried by house mice and other rodents that can cause severe brain damage in a fetus. The risk of LCMV transmission increases in winter, when rodents seek shelter in homes.
A University of Iowa law professor has found that most home health care workers are protected by few of the federal labor standards that other Americans take for granted.
A recent University of Iowa study reveals a new immune defense mechanism in normal airways and may help explain why people with cystic fibrosis (CF) are particularly susceptible to bacterial lung infections. The findings also may point the way to new approaches for treating the disease.
University of Iowa scientists have made a discovery that broadens understanding of a rapidly developing area of biology known as functional genomics and sheds more light on the mysterious, so-called "junk DNA" that makes up the majority of the human genome.
Following up on an earlier discovery that a gene called IRF6 is involved in the common birth defect cleft lip and palate, U. Iowa scientists have identified the function of the gene and revealed an unexpected role for IRF6 in the development of skin cells. The findings may have implications for wound healing and cancer.
A team of University of Iowa Health Care researchers has launched an important clinical trial of a novel therapeutic that may eventually lead to new treatments for men diagnosed with prostate cancer.
How a harmless virus called GB Virus type C (GBV-C) protects against HIV infection is now better understood. Researchers at the Department of Veterans Affairs (VA) Iowa City Health Care System and the University of Iowa have identified a protein segment that strongly inhibits HIV from growing in cell models.
Chicago Cubs first baseman Derrek Lee today announced his partnership with Boston Celtics CEO and co-owner Wyc Grousbeck and the Carver Nonprofit Genetic Testing Laboratory at the University of Iowa Roy J. and Lucille A. Carver College of Medicine to combat Leber congenital amaurosis (LCA), an important cause of genetic blindness in children.
Asthma experts are trying to ensure that an asthma drug combination is prescribed only when truly necessary. The long-acting asthma drug salmeterol used in combination with an inhaled corticosteroid can dangerously worsen asthma for a small subgroup of people with the condition.
The cycle of friendships, aggression and social power among pre-teen girls is the topic of a recent study by Ana Campos, a Department of Sociology graduate student in the College of Liberal Arts and Sciences at the University of Iowa.
Two University of Iowa sociologists suggest that routine racial misidentification causes high levels of emotional distress and is more likely to make someone contemplate or attempt suicide. Lisa Troyer and Mary Campbell, both sociology professors in the UI College of Liberal Arts and Sciences, presented their paper on this topic at the annual meeting of the American Sociological Association.
A five-year, $14.6 million grant from the National Eye Institute of the National Institutes of Health will fund an international, multidisciplinary effort led by the University of Iowa to leverage two recent genetic discoveries into possible treatments for age-related macular degeneration (AMD).
Disclosing medical errors made by physicians is extremely important yet often extremely difficult. Two University of Iowa studies examine why this is the case and how increased understanding might help patients, doctors and health care systems overall.
Going back to school can be exciting -- and stressful, especially for kids ages 5 to 7 who are at risk of having wetting accidents. About 15 percent of children in the early grades have daytime accidents. A pediatric urologist suggests ways to prevent accidents and help kids learn bladder control.
For the past three years, students, staff and volunteers from the University of Iowa Museum of Natural History, UI Department of Geoscience in the College of Liberal Arts and Sciences and the Office of the State Archaeologist have been excavating, analyzing and carefully reconstructing the bones of an ice-age giant sloth from a site near Shenandoah, Iowa.
Children who attend school near large-scale livestock farms known as concentrated animal feeding operations (CAFOs) may be at a higher risk for asthma, according to a new study by University of Iowa researchers.
Medicare beneficiaries with heart failure could benefit from new strategies to decide who qualifies for lifesaving implantable cardioverter defibrillators (ICDs).
Understanding the meaning behind a person's posture or body movement comes easily to many people and helps guide how we react to others socially. But people with schizophrenia, even those who have mild to moderate symptoms and take medications, are not fluent in understanding body language.
Researchers have uncovered unexpected and fundamental problems in predicting case durations for MRI and CT scans done under anesthesia. The research team subsequently figured out the cause of this troublesome patient scheduling problem, and determined and implemented a solution that has improved delivery of health care for pediatric patients.
Heart attack patients are about 15 percent less likely to be treated with bypass surgery or angioplasty within the first days of incident in states with certificate of need regulations. However, they are no more likely to have adverse events than comparable patients treated in states without CON.
As debate about the right to die and end-of-life care continues to swirl around the country, new research from the University of Iowa shows that for some patients and their families, these decisions should include consideration of both physical and mental health.
Early intervention and long-term treatment with electrical stimulation, which causes muscle contraction and exerts mechanical loading on the targeted bone, can significantly reduce the severe osteoporosis and muscle atrophy caused by spinal cord injury, according to University of Iowa researchers.
Trade between countries usually involves products. However, one successful export from the United States to the Netherlands, Norway and several other countries is a cognitive therapy treatment program created by University of Iowa experts to help people with borderline personality disorder.
Problem gambling runs in families, according to a study published online in the journal Psychiatry Research. The study also found an excess of alcoholism, drug disorders and antisocial personality disorder in families with pathological gamblers.
The University of Iowa Libraries will preserve historical documents damaged by Hurricane Katrina, starting with documents and manuscripts from the Jefferson Davis Library in Biloxi, and the Biloxi Public Library. UI librarians hope to encourage other preservation experts to help restore documents damaged by the hurricane.
Physicians must consider a number of variables when treating couples who cannot naturally conceive because of factors involving both the woman and man. A new model helps experts better predict outcomes and choose the treatment method most likely to help the couple achieve pregnancy.
The body armor worn by future U.S. soldiers likely will have a University of Iowa connection, thanks to a $1.6 million, three-year contract the army has signed with the UI's Virtual Soldier Research Program.
The University of Iowa's Center for Macular Degeneration, a world leader in the discovery of the genetic basis of blinding eye disease, will be able to significantly advance its mission with the creation of a large-scale nonprofit genetic testing laboratory, made possible by two gifts totaling $6.2 million.
University of Iowa radiologist, Malik Juweid, M.D., outlines the advantages and limitations of PET imaging in assessing cancer therapy and suggests that increasing the role of PET imaging has the potential to improve cancer care management.
A University of Iowa law professor and Middle East expert said she is shocked by the results of this week's Palestinian elections and likens them to a political earthquake. Includes links to audio clips.
An expert on methamphetamine and other substance abuse finds some positives in a recent state report on meth lab reduction in Iowa. However, the report also underscores ongoing meth supply and use problems in the state.
Study indicates babies conceived through in vitro fertilization have a slightly increased risk of major birth defects, such as heart or muscle and skeletal defects, compared to babies conceived naturally. Nearly 1 percent of all children born in the United States are conceived through IVF.
A greater percentage of high schools had automated external defibrillators (AEDs) -- devices that can be used to treat cardiac arrest victims -- than senior centers, despite the fact that cardiac arrests appear more common in senior centers.
Two sociologists have combined historical and sociological data to arrive at a new theory explaining the disproportionate violence in the southern United States. The South's legacy of lynching has contributed to a culture in which violence and taking the law into one's own hands are considered appropriate means of resolving disputes.
Having a first alcoholic drink at the early age of 12, 13 or 14 might be influenced more by a child's tendency to do things like lie, steal or skip school than by a family history of alcohol dependency, according to a new study.
A virus that typically infects insects could aid the development of gene therapy treatment for Hemophilia A, a condition in which a bump on the knee can cause serious internal bleeding in people. Researchers used the virus to create a sustained, partial correction to bleeding problems in mice.
Working with mice, University of Iowa scientists and colleagues from Okayama University, Japan, have shown that it is possible to cure a certain type of hereditary deafness by silencing a gene that causes hearing loss.
Emergency physicians who have the greatest fear of malpractice suits are more likely than their colleagues to admit and order tests for patients with chest pain or other heart symptoms, even if those patients are at low risk for actual problems.
Space physicist Don Gurnett says that NASA's Voyager 1 spacecraft has crossed a boundary called the "termination shock," one of the last milestones it will encounter before leaving the solar system and entering interstellar space.
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