Latest News

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A research team led by the Icahn School of Medicine at Mount Sinai (Icahn Mount Sinai) has built the first cellular model to depict the evolution of acute myeloid leukemia (AML), from its early to late stages. By using gene editing technologies to alter genes that make cells malignant, the team was able to identify potential therapeutic targets for early disease stages. The study was reported in the journal Cell Stem Cell in February.

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The clinical research conducted through the Center will investigate how to use light to improve people’s lives by stabilizing their circadian rhythms, the natural internal clock that regulates the body’s sleep-wake cycle. Researchers will study how light, either from daylight or electric indoor light, affects circadian rhythms in various populations, from the very young to the very old, including patients with COVID-19, cancer, Alzheimer’s disease, depression, and other illnesses. The goal is to help abate symptoms and improve their sleep, mental health, and cognition.

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Wearable devices can identify COVID-19 cases earlier than traditional diagnostic methods and can help track and improve management of the disease, according to a Mount Sinai study.

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Today Mount Sinai announces Palliative Care at Home, a program to care for seriously ill patients in the comfort and safety of their own homes, while avoiding unnecessary hospitalizations.

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Mount Sinai researchers have published one of the first studies using a machine learning technique called “federated learning” to examine electronic health records to better predict how COVID-19 patients will progress.

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February is American Heart Month and cardiologists from the Mount Sinai Health System are sharing tips on heart disease prevention to lower the risk of heart attack, stroke, and COVID-19.

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This is the first study to demonstrate that there is no difference in blood clots when transgender women remain on estrogen hormone therapy for gender affirming surgery. Because both estrogen therapy and surgery can increase a person’s risk of blood clots, experts had long suggested that transgender women stop taking estrogen when undergoing gender affirming surgery. However, there was previously no published data on the blood clot risk specific to transgender women undergoing surgery.

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Girls who are emotionally neglected or severely sexually abused early in their lives report riskier sexual behaviors during adolescence, Mount Sinai researchers report. The findings highlight the need—and suggest the potential for tailored approaches—to promote healthy sexual development in vulnerable populations.

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Retinal cells derived from a cadaver human eye survived when transplanted into the eyes of primate models, an important advance in the development of cell therapy to treat blindness, according to a study published on January 14 in Stem Cell Reports.

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The Tisch Cancer Institute at Mount Sinai has been awarded a $1.9 million grant by the National Cancer Institute for an innovative study that will explore the mechanisms that enable tumor cells to spread from their original site but remain dormant for some time before becoming metastatic and threatening the lives of patients.

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The Icahn School of Medicine at Mount Sinai has launched a new center for psychedelics research. The Center for Psychedelic Psychotherapy and Trauma Research pursues a multipronged clinical and research approach to discovering novel and more efficacious therapies for post-traumatic stress disorder (PTSD), depression, anxiety, and other stress-related conditions in the veteran and civilian population.

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Critical Step Toward Developing Precision Medicine Treatments

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The Seaver Autism Center for Research and Treatment at the Icahn School of Medicine at Mount Sinai and Rumi Scientific announced today that they will team up to initiate a drug discovery pipeline for rare genetic disorders that carry a high risk of autism.

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Study offers a key finding in the development of a promising treatment

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New study illustrates how studying diverse populations can help predict patient outcomes and reduce health disparities

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Substances present in cooked meats are associated with increased wheezing in children

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Royalty Pharma today announced a charitable contribution by Royalty Pharma in the amount of $1,000,000 to Mount Sinai Health System.

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Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at?

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The Dubin Breast Center of The Tisch Cancer Institute at the Mount Sinai Health System celebrated its 10th anniversary during its annual gala on Monday, December 7, 2020. The evening honored Eva Andersson-Dubin, MD, founder of the Center and a Mount Sinai trustee, and Elisa Port, MD, FACS, the Center’s Director and Chief of Breast Surgery for the Mount Sinai Health System, and raised more than $2.3 million to benefit the Dubin Breast Center. The center is part of The Tisch Cancer Institute, a National Cancer Institute-designated cancer center.

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Technology may lead to quicker triage and treatment based on patient data and scans

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The majority of pregnant women who tested positive for COVID-19 on arrival to the delivery room were asymptomatic, according to a new paper by Mount Sinai researchers.

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A vaccine that induces immune responses to a wide spectrum of influenza virus strains and subtypes has produced strong and durable results in early-stage clinical trials in humans, Mount Sinai researchers have found.

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Podcast from the Icahn School of Medicine at Mount Sinai offers a glimpse into the real story of how science and medicine moves forward, one smart person at a time.

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Mount Sinai Doctors has opened a new location in Yonkers, New York, with services that include primary care, cardiology, neurology, and gastroenterology. The new, state-of-the-art facility is 6,000 square feet and located on the ground floor of the historic Boyce Thompson Center at 1086 North Broadway.

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Multiple honors recognize leadership and exemplary scientific and educational contributions

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The U.S. Centers for Medicare & Medicaid Services (CMS) announced today that the agency had approved a waiver allowing Mount Sinai Health System to enroll a broader group of Medicare patients into its Hospitalization at Home (HaH) program. The move is a game changer as hospitals in New York City brace for a continued increase in COVID-19 cases.

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A comprehensive “proteogenomic” analysis of the proteins, genes, and RNA transcription involved in pediatric brain tumors has yielded a more complete understanding of these tumors, which are the leading cause of cancer-related deaths in children. The results could help physicians more accurately identify different types of tumors and methods for treating them.

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Researchers from Mount Sinai and the National Center for Geriatrics and Gerontology in Japan have identified new molecular mechanisms driving late-onset Alzheimer’s Disease.

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The Arnhold Institute for Global Health at the Icahn School of Medicine Mount Sinai will host a virtual event on World AIDS Day.

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Growing numbers of COVID-19 cases and deaths are troubling; facemasks can slow the trend

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In recognition of its expertise in treating adults with congenital heart disease (ACHD), the Mount Sinai Adult Congenital Heart Disease Center has been accredited by the Adult Congenital Heart Association (ACHA) as a Comprehensive Care Center.

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• New study will assess the potential impact of nintedanib in patients developing pulmonary fibrosis following acute lung injury from COVID-19 infection • Research collaboration will lead to valuable insights about pulmonary fibrosis in the growing COVID-19 patient population

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Noted Alzheimer’s researcher will assume new role on January 1, 2021

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Research may lead to identifying novel therapies for cardiac patients

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Only program in New York City to receive prestigious recognition

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A vaccine created to prevent the recurrence of the deadly skin cancer melanoma is about twice as effective when patients also receive two components that boost the number and effectiveness of immune system cells called dendritic cells, according to phase 2 clinical trial results published in Nature Cancer in November.

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The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol—the so-called “bad” cholesterol—by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and other global academic sites has found.

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Mount Sinai clinical trial results could help lead to FDA approval

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Mount Sinai researchers have revealed new insights into how the body regulates craniofacial development in newborns, which can sometimes lead to birth defects such as cleft lip or palate.

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The COVID-19 Research Symposium, hosted by the Mount Sinai Clinical Intelligence Center (MSCIC), is a one-day comprehensive review of advances in research by the Mount Sinai Health System to better understand and treat the coronavirus known as COVID-19.

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Thailand’s Royal Family has named Valentin Fuster, MD, PhD, Director of Mount Sinai Heart and Physician-in-Chief of The Mount Sinai Hospital, a winner of the 29th annual Prince Mahidol Award in the field of Medicine.

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Results suggest the need for widespread surveillance testing to reduce COVID-19 transmission in group settings

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Mount Sinai researchers have developed machine learning models that predict the likelihood of critical events and mortality in COVID-19 patients within clinically relevant time windows.

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2020 Recipient of Pinnacle of Excellence Award

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The virus that causes COVID-19 was present in New York City long before the city’s first case of the disease was confirmed on March 1

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A groundbreaking new type of cancer immunotherapy developed at the Icahn School of Medicine at Mount Sinai trains the innate immune system to help it eliminate tumor cells through the use of nanobiologics, tiny materials bioengineered from natural molecules that are paired with a therapeutic component, according to a study published in Cell in October.

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The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.