Irvine, Calif., April 15, 2020 – On Tuesday, California Gov. Gavin Newsom suggested that reopening the state’s economy will require six steps, the first of which involves “tracing and tracking individuals” in order to identify those who need to remain in isolation. Researchers at the University of California, Irvine have developed a tool that could be instrumental in this effort.
Irvine, Calif., April 14, 2020 — Four professors at the University of California, Irvine – historian Mark LeVine, scientist Andrej Lupták, sculptor Jennifer Pastor and journalist Amy Wilentz – have been named 2020 Guggenheim Fellows. Jennifer Pastor. UCI The faculty members were among 175 U.S. and Canadian scholars, researchers, artists and writers chosen by the John Simon Guggenheim Memorial Foundation from a pool of nearly 3,000 applicants.
Henry J. Klassen, MD, PhD, professor and director of the Stem Cell and Retinal Generation Program at the UCI School of Medicine, Gavin Herbert Eye Institute, and founder of jCyte, Inc., was awarded a $6.6 million dollar grant from the California Institute for Regenerative Medicine (CIRM) for a clinical trial targeting retinitis pigmentosa (RP).
Irvine, Calif., April 13, 2020 – Researchers at the University of California, Irvine and other institutions have architecturally designed plate-nanolattices – nanometer-sized carbon structures – that are stronger than diamonds as a ratio of strength to density. In a recent study in Nature Communications, the scientists report success in conceptualizing and fabricating the material, which consists of closely connected, closed-cell plates instead of the cylindrical trusses common in such structures over the past few decades.
Amyloid is a key feature of Alzheimer’s disease, but the accumulation of these sticky proteins may not be the only risk factor for developing Alzheimer’s disease, according to a new study published this week. Other, modifiable risk factors, such as the amount of fats in our blood and how efficiently our bodies generate energy could also play important roles.
Irvine, Calif., April 2, 2020 — Chad T. Lefteris, an executive with considerable experience in integrated and academic health systems, has been named CEO of UCI Health, overseeing Orange County’s only academic medical center and all clinical and patient-serving operations. His appointment was approved by the University of California Board of Regents.
Researchers from the University of California, Irvine have conducted a statistical analysis that predicts more than 70,000 heart attacks, strokes and other adverse cardiovascular events could be prevented each year in the U.S. through the use of a highly purified fish oil therapy.
Irvine, Calif., March 23, 2020 – While government officials and news organizations work to communicate critical risk assessments and recommendations to the public during a health crisis such as the new coronavirus pandemic, a related threat may be emerging, according to researchers at the University of California, Irvine: psychological distress resulting from repeated media exposure to the crisis.
Irvine, Calif., March 23, 2020 – Researchers at the University of California, Irvine have shown that they can give cells a short-term boost of energy through mitochondrial transplantation. The team’s study, published today in the Journal of the American Heart Association, suggests that mitochondrial transplantation could one day be employed to cure various cardiovascular, metabolic and neurodegenerative disorders – and even offer a new approach to the treatment of cancer.
Irvine, Calif., March 23, 2020 – East Antarctica’s Denman Glacier has retreated 5 kilometers, nearly 3 miles, in the past 22 years, and researchers at the University of California, Irvine and NASA’s Jet Propulsion Laboratory are concerned that the shape of the ground surface beneath the ice sheet could make it even more susceptible to climate-driven collapse.
A team of University of California, Irvine researchers have published the first comprehensive overview of the major changes that occur in mammalian skin cells as they prepare to heal wounds. Results from the study provide a blueprint for future investigation into pathological conditions associated with poor wound healing, such as in diabetic patients.
Irvine, Calif., March 18, 2020 – During the exceptionally warm Arctic summer of 2019, Greenland lost 600 billion tons of ice, enough to raise global sea levels by 2.2 millimeters in two months. On the opposite pole, Antarctica continued to lose mass in the Amundsen Sea Embayment and Antarctic Peninsula but saw some relief in the form of increased snowfall in Queen Maud Land, in the eastern part of the continent.
Irvine, Calif., March 16, 2020 – Farmers in California’s Central Valley are not known for their love of government regulations, but those same growers have seen a boost in the productivity of their high-value crops – and greater earnings – as a result of the Golden State’s strict air pollution controls. For a study published today in Nature Food, researchers at the University of California, Irvine and other institutions conducted a statistical analysis of pollution exposure and yields from 1980 to 2015 on a key sector making up about 38 percent of the state’s total agricultural output: perennial crops such as almonds, grapes, nectarines, peaches, strawberries and walnuts.
New discovery in breast cancer could lead to better strategies for preventing the spread of cancer cells to other organs in the body, effectively reducing mortality in breast cancer patients. According to a study, published today in Nature Cell Biology, breast cancer cells shift their metabolic strategy in order to metastasize. Instead of cycling sugar (glucose) for energy, they preferentially use mitochondrial metabolism.
Irvine, Calif., March 5, 2020 — The implementation of California Senate Bill 54 – which limits, but does not prohibit, state and local police cooperation with federal immigration authorities – did not cause an increase in crime, according to a new study from researchers at the University of California, Irvine. This is the first systematic analysis to be conducted on the impact of the measure since California’s “sanctuary state” status went into effect on Jan.
In the past, biologically-active peptides – small proteins like neurotoxins and hormones that act on cell receptors to alter physiology – were purified from native sources like venoms and then panels of variants were produced in bacteria, or synthesized, to study the structural basis for receptor interaction. A new technique called zombie scanning renders these older processes obsolete.
With drug resistance a major challenge in the fight against cancer, a discovery by University of California, Irvine biologists could offer new approaches to overcoming the obstacle. Their research reveals that a mechanism enabling the diseased cells to scavenge dead cell debris for nourishment holds a pivotal role.
Human fingers are sculpted from a primitive pad-like structure during embryonic development. Sometimes, this process goes awry and babies are born with fused fingers or toes. A new study from the University of California, Irvine reveals new factors involved in the congenital malformation called syndactyly.
New study reveals potential for developing novel antibody-based antitoxins against botulinum neurotoxins (BoNTs), including the most commonly used, yet most toxic one, Botox.
New cancer immunotherapy approaches are revolutionizing treatment options for breast cancer patients. However, many lead to insufficient immune responses rendering the therapies incapable of completely eradicating tumors. In a new study, published today in Science Immunology, University of California, Irvine researchers determined the molecular features of certain cells associated with breast cancer, which may open up new avenues into improving cancer immunotherapy.
Five-year-old Emlee jumps high, runs fast and likes to pirouette around the living room in her white ballet slippers. Her mom, Karalayne Maglinte, calls her a miracle. Indeed, Emlee is the embodiment of the word: She’s one of the reasons Maglinte is alive today. Another reason: High-risk pregnancy physicians and cancer specialists at UCI Health were able to help the Fontana woman when no one else could.
Greg Weiss, a backpack slung over his shoulder, walks through Aldrich Park. The professor of chemistry has just left a meeting at UCI’s Paul Merage School of Business about University Lab Partners, Orange County’s first wet lab incubator, located at UCI Beall Applied Innovation. Weiss, who sits on the scientific advisory board of ULB, from which he plans to launch future companies, is heading to his office, clear on the other side of campus, in the Natural Sciences I building.
The long, winding river that is the human digestive tract is prone to all manner of diseases, from the merely irritable to the decidedly deadly. All fall under the purview of the H.H. Chao Comprehensive Digestive Disease Center, an internationally lauded assemblage of doctors, pooled knowledge and technology devoted to gastrointestinal health gathered under one roof at the UCI Medical Center campus, in Orange.
When you’re facing a cancer diagnosis with an average survival span of 12 to 18 months, every milestone is a victory. That makes each wedding invitation, graduation announcement and birthday photo that UCI neuro-oncologist Dr. Daniela Bota receives from her patients a cherished validation of her 12 years of groundbreaking research on glioblastoma multiforme, the most aggressive form of brain cancer.
Like most people, John Gifford wasn’t looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018. The Riverside man, 65, was concerned about his family history of colorectal cancer and had dutifully scheduled an appointment with UCI Health gastroenterologist Dr. William Karnes. The exam turned out to be intriguing and enlightening – a far cry from what one expects during a colonoscopy, Gifford recalls with a laugh.
A secret to survival amid rising global temperatures could be dwelling in the tidepools of the U.S. West Coast. Findings by University of California, Irvine biologists studying the genome of an unusual fish residing in those waters offer new possibilities for humans to obtain dietary protein as climate change imperils traditional sources.
Low oxygen levels in the heart have long been known to produce life-threatening arrhythmias, even sudden death. Until now, it was not clear how. New findings, in a study led by Steve A. N. Goldstein, MD, PhD, vice chancellor for Health Affairs at the University of California, Irvine, and distinguished professor in the UCI School of Medicine Departments of Pediatrics and Physiology & Biophysics, reveal the underlying mechanism for this dangerous heart disorder.
Irvine, Calif., Feb. 18, 2020 – A new artificial intelligence-enhanced video compression model developed by computer scientists at the University of California, Irvine and Disney Research has demonstrated that deep learning can compete against established video compression technology. Unveiling their work in December at the Conference on Neural Information Processing Systems in Vancouver, British Columbia, the UCI/Disney Research team members showed that their compressor – while still in an early phase – yielded less distortion and significantly smaller bits-per-pixel rates than classical coding-decoding algorithms such as H.
Irvine, Calif., Feb. 13, 2020 — Popular gaming personality Pokimane has donated $50,000 to the University of California, Irvine for student scholarships in its esports program. An initial $25,000 gift this year will be combined with the remaining $25,000 in 2021 to create an endowment that will fund tuition and fees for gamers selected by UCI Esports.
Irvine, Calif., Feb. 10, 2020 — A $5 million gift from UCI Foundation trustee Stacey Nicholas will endow and rename a program serving both The Henry Samueli School of Engineering and the Donald Bren School of Information & Computer Sciences – the UCI Office of Access & Inclusion – that supports the recruitment, retention and graduation of students from historically excluded populations who are underrepresented in science, technology, engineering and math.
Irvine, Calif., Feb. 4, 2020 — For the second year in a row, the University of California, Irvine is the most popular UC campus for the state’s college-bound high school seniors. A total of 72,391 aspiring in-state freshmen applied to attend UCI this fall, up 2,000 from last year and more than applied to any of the other eight UC undergraduate campuses.
Irvine, Calif., Jan. 27, 2020 – A neural network-driven Earth system model has led University of California, Irvine oceanographers to a surprising conclusion: Phytoplankton populations in low-latitude waters will expand by the end of the 21st century. The unexpected simulation outcome runs counter to the longstanding belief by many in the environmental science community that global climate change will make tropical oceans inhospitable to phytoplankton, which form the base of the aquatic food web.
Individuals with a history of early life adversity (ELA) are disproportionately prone to opioid addiction. A new UCI-led study reveals why. Published in Molecular Psychiatry, the study titled, “On the early life origins of vulnerability to opioid addiction,” examines how early adversities interact with factors such as increased access to opioids to directly influence brain development and function, causing a higher potential for opioid addiction.
Irvine, Calif., Jan. 21, 2020 – Community collaboration and high-resolution maps are key to effective flood risk management, according to civil engineers and social scientists at the University of California, Irvine and other institutions. In a study published recently in the American Geophysical Union journal Earth’s Future, the researchers report on a successful new process called “collaborative flood modeling” for addressing the increasing threat of rising waters brought on by climate change, aging infrastructure and rapid urban development.
When University of California, Irvine neurobiologist Carey Y.L. Huh, Ph.D., set her sights on discovering more about amblyopia, she brought personal insight to her quest. As a child, Huh was diagnosed with the condition, which is often called “lazy eye.” he and her colleagues have just found that amblyopia originates in an earlier stage of the visual pathway than was previously thought. Their research, which raises the possibility of new treatment approaches, appears in the Journal of Neuroscience.
EVENT: UCI will celebrate the upcoming Lunar New Year – heralding the Year of the Rat – with an academic discussion, multicultural entertainment, artistic demonstrations, interactive workshops, a Disney-sponsored raffle, lion and dragon parades, food, a laser light show and more. WHEN/WHERE: 2-6:30 p.m. Tuesday, Jan. 21, at the Multipurpose Academic & Administrative Building (bldg.
The UCI School of Medicine, in partnership with Chenega Healthcare Services, LLC and MedCognition, was awarded a $1.2 million contract through the Medical Technology Enterprise Consortium to examine the psychological effects of augmented reality (AR) medical simulation training.
Irvine, Calif., Jan. 6, 2020 — Young people’s view of their family’s social status was more strongly associated with their mental health and readiness for future education and work than how much money, education or occupational prestige their parents have, according to new research led by the University of California, Irvine.
Irvine, Calif., Dec. 23, 2019 — From probing the ocean depths to deciphering human health mysteries, researchers across scientific disciplines are increasingly including microbiomes in their work. The Microbiome Centers Consortium has been launched by two University of California, Irvine School of Bioscience faculty members to advance growth in this life science field, increasingly recognized as relevant to many other disciplines and industrial applications.
Irvine, Calif., Dec. 19, 2019 – Greenland is losing ice mass seven times faster than in the 1990s, a pace that matches the Intergovernmental Panel on Climate Change’s high-end warming scenario – in which 400 million people would be exposed to coastal flooding by 2100, 40 million more than in the mid-range prediction. The alarming update resulted from the Ice Sheet Mass Balance Intercomparison Exercise, a project involving nearly 100 polar scientists from 50 international institutions, among them two from the University of California, Irvine.
Irvine, Calif., Dec. 12, 2019 – A University of California, Irvine-led team of glaciologists has unveiled the most accurate portrait yet of the contours of the land beneath Antarctica’s ice sheet – and, by doing so, has helped identify which regions of the continent are going to be more, or less, vulnerable to future climate warming.
Irvine, Calif., Dec. 10, 2019 — The University of California, Irvine Alumni Association will bestow its highest honor, the Lauds & Laurels Extraordinarius award, to alumni couple Carol Choi ’85 and Eugene Choi ’86, MBA ’01, for their exemplary service and contributions to the university and community. “We are proud to celebrate the Chois’ remarkable impact through this distinguished and well-deserved award,” said Brian T.
While beauty may be in the eyes of the beholder, breathing is an agreed upon necessity. A new study reveals how an emerging technique in rhinoplasty does more than improve physical appearance.
The brightest minds in neuroscience came together Nov. 21 for the UCI Brain Launch Event, an interdisciplinary academic initiative set to define and expand the horizons of brain research at UCI and beyond. More than 700 attended the day-long symposium at the Beckman Center of the National Academies of Sciences & Engineering, where Michael Yassa, director of UCI Brain, introduced a host of new technologies that redefine brain research, including a collaboration with the Claire Trevor School of the Arts.
Irvine, Calif., Nov. 26, 2019 — Nine University of California, Irvine researchers in areas ranging from neurodevelopment and chemical synthesis to labor economics and library sciences have been named fellows of the American Association for the Advancement of Science, the world’s largest general scientific society. A total of 443 AAAS members are being honored this year for their efforts to further science or its applications.
Weekend binge drinking and chronic alcoholism have long been known to contribute to alcoholic liver diseases (ALD). A new study reveals how alcohol affects the liver's circadian rhythm, uncovering a potential new target for ALD treatments.
Researchers from the University of California, Irvine developed a breakthrough cell therapy to improve memory and prevent seizures in mice following traumatic brain injury. The study, titled “Transplanted interneurons improve memory precision after traumatic brain injury,” was published today in Nature Communications.
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