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Researchers at the Icahn School of Medicine report that roflumilast cream (ARQ-151), which contains a highly potent, selective phosphodiesterase-4 (PDE4) inhibitor demonstrated significant improvements in patients with psoriasis signs and symptoms in as early as two weeks. The phase 2b trial results showed that when patients with plaque psoriasis applied topical roflumilast once-daily they reported clear skin as well as improvement in itch and burden of disease. The results of the paper were published online today in The New England Journal of Medicine.

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• Ensures close connection between patient and physician for remote hypertension monitoring • Complements Mount Sinai’s growing telehealth initiative • Medicare-covered and generally at no cost to patients, depending on coverage

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Mount Sinai Health System and Cross County Cardiology announced a new cooperative partnership today that will include five cardiology practices located throughout Bergen and Hudson counties in New Jersey. Cross County Cardiology-Mount Sinai Doctors will work to enhance clinical care for patients with cardiovascular disease bringing the most advanced techniques within the field of cardiology and vascular care to the region.

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A health care system (The Mount Sinai Hospital) and a Medicaid payer (Healthfirst) partnered to develop an educational intervention and payment redesign program to improve timely postpartum visits for low-income high-risk mothers in New York City between April 2015 and October 2016.

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The study will aim to understand whether systemic medications and biologics, such as dupilumab—a monoclonal antibody that binds to an inflammatory molecule, IL-4 receptor alfa, and inhibits the inflammatory response that leads to rashes and itching from atopic dermatitis/eczema—may have a positive or negative impact on COVID-19 responses in patients who have the disease.

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Mount Sinai and Emergent to conduct clinical trials to evaluate COVID-HIG for post-exposure prophylaxis of COVID-19 in front-line health care workers and to support a potential Expanded Access Program for military personnel with funding from the U.S. Department of Defense - ImmunoTek to extend operating license and provide training to Mount Sinai to establish onsite plasma collection to support production of COVID-HIG

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Researchers at the Seaver Autism Center for Research and Treatment at Mount Sinai have started recruiting participants for a new clinical trial to evaluate the safety, tolerability, and efficacy of a low dose of ketamine in children diagnosed with ADNP syndrome (also known as Helsmoortel-VanDerAa syndrome), a rare neurodevelopmental disorder caused by mutations in the activity dependent neuroprotective protein (ADNP) gene.

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Affiliation will include newly formed comprehensive cancer program, co-branded emergency department, and integrated internal medicine and specialty physician practices

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Patients with HIV who were hospitalized with COVID-19 did not experience poorer outcomes compared to a similar comparison group of patients.

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Mount Sinai researchers have for the first time identified reproductive and metabolic subtypes of polycystic ovary syndrome (PCOS) that are associated with novel gene regions.

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Like a scene out of “Invasion of the Body Snatchers,” a virus infects a host and converts it into a factory for making more copies of itself.

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Mount Sinai Health System is beginning the first clinical trial in the New York metropolitan region of an immune-boosting therapy in COVID-19 patients.

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If authorized for quantitative use, the assay could be used to provide a numeric result for the concentration of neutralizing anti-COVID-19 antibodies in plasma.

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Mount Sinai Health System has appointed Beth Oliver, DNP, RN, to the role of Senior Vice President and Chief Nursing Executive.

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Mount Sinai Health System has appointed Kristin Myers, MPH, as Executive Vice President, Chief Information Officer, and Dean for Information Technology.

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Study findings may help doctors better triage coronavirus patients admitted to the hospital

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Grant Will Enable Development of AI Tools to Enhance Care and Evidence-based Medicine for Treating COVID-19 Patients

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Researchers at Mount Sinai have discovered that human acute myeloid leukemia (AML) stem cells are dependent on a transcription factor known as RUNX1, potentially providing a new therapeutic target to achieve lasting remissions or even cures for a disease in which medical advances have been limited.

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Asking elderly patients how much they exercise can help predict their risk of heart disease and death, Mount Sinai and collaborative researchers say.

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Study Could Help Doctors Understand and Treat Common Conditions

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Fitness challenge honors and supports health care heroes at Mount Sinai Health System and Academic Centers Across the Country. Goldman Sachs & Co., Peloton, Discovery, NBCUniversal Owned Television Stations, dtx and Pinterest Support First-Ever Collective Medical Center Campaign.

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Patients hospitalized with COVID-19 who received convalescent plasma demonstrated improved survival and were more likely than matched control patients to remain the same or have improvements in their supplemental oxygen requirements, according to a study conducted by researchers at the Icahn School of Medicine at Mount Sinai and published today on pre-print server medRxiv.

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Mount Sinai scientists have identified biological markers present in childhood that relate to the degenerative and often fatal neurological disease called amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig’s disease, according to a study published in the Annals of Clinical and Translational Neurology in May.

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- Kantaro Biosciences partners with Bio-Techne for manufacturing and global kit distribution - Scaled kit production to enable clinical laboratories to conduct 10M tests per month is planned to begin in July

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Mount Sinai researchers are the first in the country to use artificial intelligence (AI) combined with imaging, and clinical data to analyze patients with coronavirus disease (COVID-19).

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A clinical trial led by Mount Sinai researchers has showed for the first time that combining chemotherapy and immunotherapy can slow down metastatic bladder cancer. The trial also showed that immunotherapy alone may be an option for a subset of patients with metastatic bladder cancer if their tumor expresses a high level of a protein called PD-L1 according to the study, published in The Lancet in May.

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Chest X-rays performed on young and middle-aged adults with COVID-19 when they arrive at the emergency room can help doctors predict who is at higher risk of severe illness and intubation, Mount Sinai researchers report.

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COVID-19 Crisis Spurs Institute to Understand and Combat Health Disparities in Underserved Communities. Earvin “Magic” Johnson, five-time NBA champion, and New York State Senator Brian Benjamin Among Industry and Public Health Leaders to Join Institute Task Force.

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Center to provide post-multidisciplinary care and psychosocial resources for patients recovering from pandemic disease COVID-19 Registry and clinical trials component will define new standards of care for patients

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A new artificial intelligence (AI) algorithm developed by researchers at New York Eye and Ear Infirmary of Mount Sinai (NYEE) can rapidly and accurately detect age-related macular degeneration (AMD), a leading cause of vision loss in the United States.

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New study identifies that differences in insulin resistance can explain in part the disparities in breast cancer survival between black and white women

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A New Nest Camera Console Enhances Safety of Patients and Staff; Reduces PPE Demands

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Research could change standard of care protocols to prevent clotting associated with coronavirus

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How neighborhood racial and economic spatial polarization, an extreme form of residential segregation, influences maternal health.

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Center will address psychosocial impact of COVID-19 among frontline health workers; Focus is on screening, treatment, and research

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The highly targeted antibody may block the coronaviruses’ ability to enter human lung cells

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Researchers at Mount Sinai have found that a novel class of genes known as long non-coding RNAs (lncRNAs) expressed in the brain may play a pivotal role in regulating mood and driving sex-specific susceptibility versus resilience to depression.

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The musicians of Carnegie Hall, featuring a song and words of support by Jimmy Buffet and others join forces to raise money for the front-line health care staff at the Mount Sinai Health System

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Today, the Mount Sinai Laboratory (MSL), Center for Clinical Laboratories received emergency use authorization from the U.S. Food and Drug Administration (FDA) for an antibody test that was developed, validated, and launched at Mount Sinai by a team of internationally renowned researchers and clinicians of the Icahn School of Medicine at Mount Sinai. This test detects the presence or absence of antibodies to SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19) and importantly, may also be used to identify positive specimens with an antibody titer (level) up to a dilution of 1:2880 for the identification of individuals with higher antibody titers.

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A new study from the Icahn School of Medicine at Mount Sinai suggests that blood clots, especially in the lungs, may play a role in severe cases of COVID-19.

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Project Florence enhances skills of nurses serving critically ill patients; curriculum is free to hospitals worldwide

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Lyme Campaign Seeks Participants Who Are ‘Resilient’ to the Tick-borne Disease

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Using immunotherapy immediately after chemotherapy treatment in patients with metastatic bladder cancer significantly slowed the progression of the cancer, according to results of a clinical trial led by Mount Sinai researchers published in the Journal of Clinical Oncology in April.

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Scientists at the Icahn School of Medicine at Mount Sinai have discovered a new role for the brain chemical dopamine that is independent of classic neurotransmission. The new role appears to be critical to changes in gene expression related to chronic exposure to, or abuse of, cocaine, according to a study published Friday, April 10, in the journal Science.

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Mount Sinai Health System is the first in the country to use an innovative allogeneic stem cell therapy in COVID-19 patients and will play a central role in developing and conducting a rigorous clinical trial for patients with severe acute respiratory distress syndrome, the breathing illness that afflicts people who have severe cases of COVID-19.

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First definitive molecular epidemiology study of SARS-CoV-2 in New York City to describe the route by which the virus arrived