Latest News from: JAMA - Journal of the American Medical Association

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2-Mar-2012 3:30 PM EST
Maternal Use of SSRIs Associated with Fewer Depressive Symptoms, Delayed Fetal Head Growth
JAMA - Journal of the American Medical Association

Treating pregnant women with selective serotonin reuptake inhibitors (SSRIs) appears to be associated with fewer depressive symptoms, reduced fetal head growth and a higher risk for preterm birth, but not with a delay in fetal body growth, according to a report published Online First by Archives of General Psychiatry, one of the JAMA/Archives journals.

2-Mar-2012 3:25 PM EST
Persistent Depression Linked with Cognitive Decline in Older Patients with Coronary Artery Disease
JAMA - Journal of the American Medical Association

Persistent depression symptoms may be associated with significantly greater declines in cognitive performance in older patients with coronary artery disease who underwent cardiac catheterization, according to a study published in the March issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

2-Mar-2012 3:15 PM EST
Risk for Drug Abuse in Adopted Children Appears Influenced by Family, Genetics
JAMA - Journal of the American Medical Association

In a national Swedish adoption study, the risk for drug abuse appears to be increased among adopted children whose biological parents had a history of drug abuse, according to a report published Online First by Archives of General Psychiatry, one of the JAMA/Archives journals.

2-Mar-2012 3:15 PM EST
Vitamin D Intake May Be Associated with Lower Stress Fracture Risk in Girls
JAMA - Journal of the American Medical Association

Vitamin D may be associated with a lower risk of developing stress fractures in preadolescent and adolescent girls, especially among those very active in high-impact activities, according to a report published Online First by Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

2-Mar-2012 3:10 PM EST
Children with Mild Traumatic Brain Injury Appear More Likely to Have Postconcussion Symptoms
JAMA - Journal of the American Medical Association

Children with mild traumatic brain injuries appear more likely to have persistent postconcussion symptoms, including cognitive complaints such as inattention and forgetfulness, which can affect quality of life, according to a report published Online First by Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

23-Feb-2012 5:00 PM EST
Study Examines Stent Implantation Compared to Initial Medical Therapy for Stable Coronary Disease
JAMA - Journal of the American Medical Association

A meta-analysis of eight previously published clinical trials suggests that initial stent implantation for patients with stable coronary artery disease is not associated with improved outcomes compared with initial medical therapy for prevention of death, nonfatal heart attacks, unplanned revascularization or angina, according to a study published in the Feb. 27 Archives of Internal Medicine, one of the JAMA/Archives journals.

23-Feb-2012 5:00 PM EST
Behavioral Intervention in Physician Offices Linked with Modest Reductions in Waist Circumference
JAMA - Journal of the American Medical Association

A physical activity and diet program implemented by health educators in physician offices appears to be associated with modest reductions in waist circumference among obese patients, according to a report published Online First by Archives of Internal Medicine, one of the JAMA/Archives journals.

23-Feb-2012 5:00 PM EST
Use of Telephone Intervention Did Not Improve Adherence to Osteoporosis Medication Regimen
JAMA - Journal of the American Medical Association

Telephone motivational counseling sessions did not result in a statistically significant improvement in adherence to an osteoporosis medication regimen, according to a report published Online First by Archives of Internal Medicine, one of the JAMA/Archives journals.

9-Feb-2012 5:00 PM EST
Spending More Time Physically Active Associated with Better Cardiometabolic Measures Among Children
JAMA - Journal of the American Medical Association

In a study that included data for more than 20,000 children and adolescents, higher amounts of time with moderate to vigorous physical activity were associated with better cardiometabolic risk factors (such as measures of cholesterol, blood pressure and waist size), regardless of the amount of time spent sedentary, according to a study in the February 15 issue of JAMA.

9-Feb-2012 4:35 PM EST
Vitamin D Therapy Does Not Improve Certain Cardiac Measures for Patients with Chronic Kidney Disease
JAMA - Journal of the American Medical Association

Patients with chronic kidney disease who received the vitamin D compound paricalcitol for up to 48 weeks did not show improvement on measures of cardiac structure, function, or left ventricular mass, compared to patients who received placebo, according to a study in the February 15 issue of JAMA.

9-Feb-2012 4:25 PM EST
Treating Acute Sinusitis with Antibiotic Does Not Appear Helpful
JAMA - Journal of the American Medical Association

Treatment with the antibiotic amoxicillin for patients with acute uncomplicated rhinosinusitis (inflammation of the nasal cavity and sinuses) did not result in a significant difference in symptoms compared to patients who received placebo, according to a study in the February 15 issue of JAMA.

9-Feb-2012 4:20 PM EST
Short-Term Exposure to Most Major Air Pollutants Associated with Increased Risk of Heart Attack
JAMA - Journal of the American Medical Association

Short-term exposure (for up to 7 days) to all major air pollutants, with the exception of ozone, is significantly associated with an increased risk of heart attack, according to a review and meta-analysis of previous studies appearing in the February 15 issue of JAMA.

2-Feb-2012 3:15 PM EST
Study Evaluates Antibiotic Option for Treating Bladder Infection in Women
JAMA - Journal of the American Medical Association

Short-term use of the antibiotic cefpodoxime for the treatment of women with uncomplicated cystitis (bladder infection) did not meet criteria for noninferiority for achieving clinical cure compared with ciprofloxacin, a drug in the fluoroquinolone class of antibiotics for which there have been concerns about overuse and a resulting increase in resistance rates, according to a study in the February 8 issue of JAMA.

2-Feb-2012 3:15 PM EST
Rotavirus Vaccine Not Associated with Increased Risk of Intestinal Disorder in US Infants
JAMA - Journal of the American Medical Association

Although some data have suggested a possible increased risk of intussusception (when a portion of the small or large intestine slides forward into itself, like a telescope) after administration of the pentavalent rotavirus vaccine in infants, an analysis that included almost 800,000 doses administered to U.S. infants found no increased risk of this condition following vaccination, according to a study in the February 8 issue of JAMA.

2-Feb-2012 3:15 PM EST
Risk of Death From Breast Cancer Higher Among Older Patients
JAMA - Journal of the American Medical Association

Among postmenopausal women with hormone receptor-positive breast cancer, increasing age was associated with a higher risk of death from breast cancer, according to a study in the February 8 issue of JAMA.

2-Feb-2012 3:15 PM EST
Administration of Meningococcal Vaccine with Other Routine Infant Vaccines Appears Effective
JAMA - Journal of the American Medical Association

Administration of routine infant immunizations with a vaccine for serogroup B Neisseria meningitidis, a bacterium that is a cause of serious disease such as sepsis and meningitis, was effective against meningococcal strains and produced minimal interference with the response to the routine vaccinations, according to a study in the February 8 issue of JAMA.

26-Jan-2012 5:00 PM EST
Study Examines Hospital Compliance with Proposed Emergency Department Performance Measures
JAMA - Journal of the American Medical Association

Compliance with proposed emergency department length of stay measures for admitted, discharged, transferred, and observed patients does not differ significantly between safety-net hospitals (which serve higher proportion of patients with poorer health care status) and non-safety-net hospitals, addressing the issue of whether safety-net hospitals may not be able to meet certain performance measures and could be at risk of reduced funding, according to a study in the February 1 issue of JAMA.

26-Jan-2012 5:00 PM EST
Study Finds Substantial Variability in Rate of Additional Surgery After Partial Mastectomy
JAMA - Journal of the American Medical Association

Nearly one in four women who undergo a partial mastectomy for treatment of breast cancer have another surgery to remove additional tissue (reexcision), and there is substantial surgeon and institutional variation in the rate of reexcisions that cannot be explained by patients' clinical characteristics, according to a study in the February 1 issue of JAMA.

24-Jan-2012 1:15 PM EST
Prevalence of Oral HPV Infection Higher Among Men Than Women
JAMA - Journal of the American Medical Association

The overall prevalence of oral human papillomavirus (HPV) infection is approximately 7 percent among men and women ages 14 to 69 years in the United States, while the prevalence among men is higher than among women, according to a study appearing in JAMA. The study is being released early online to coincide with its presentation at the Multidisciplinary Head and Neck Cancer Symposium.

19-Jan-2012 4:00 PM EST
Study Examines Link Between Vaccinations and Exposure to Compound Widely Used in Food Packaging
JAMA - Journal of the American Medical Association

Elevated exposures in children to perfluorinated compounds, which are widely used in manufacturing and food packaging, were associated with lower antibody responses to routine childhood immunizations, according to a study in the January 25 issue of JAMA.

19-Jan-2012 3:55 PM EST
Women with Certain Type of Ovarian Cancer and BRCA Gene Mutation Have Improved Survival at 5 Years
JAMA - Journal of the American Medical Association

Among women with invasive epithelial ovarian cancer, patients having a germline (gene change in a reproductive cell that could be passed to offspring) mutation in the BRCA1 or BRCA2 genes was associated with improved 5-year overall survival, with BRCA2 carriers having the best prognosis, according to a study in the January 25 issue of JAMA.

19-Jan-2012 4:00 PM EST
Adding Proton Pump Inhibitor to Treat Poorly Controlled Asthma in Children Does Not Improve Symptoms
JAMA - Journal of the American Medical Association

Children without symptoms of gastroesophageal reflux whose asthma was being poorly controlled with anti-inflammatory treatment did not have an improvement in symptoms or lung function with the added treatment of the proton pump inhibitor lansoprazole, compared to patients who received placebo, according to a study in the January 25 issue of JAMA. Use of lansoprazole was associated with increased adverse events.

29-Dec-2011 4:00 PM EST
Bariatric Surgery Associated with Reduction in Cardiovascular Events and Death
JAMA - Journal of the American Medical Association

Among obese individuals, having bariatric surgery was associated with a reduced long-term incidence of cardiovascular deaths and events such as heart attack and stroke, according to a study in the January 4 issue of JAMA.

29-Dec-2011 4:00 PM EST
When Overeating, Calories, Not Protein, Contribute to Increase in Body Fat
JAMA - Journal of the American Medical Association

In a study conducted among 25 healthy individuals living in a controlled setting who were randomized to overconsumption of different levels of protein diets, those consuming the low-protein diet had less weight gain compared to those consuming normal and high protein diets, and calories alone, and not protein appeared to contribute to an increase in body fat, according to a study in the January 4 issue of JAMA. The researchers also found that protein did contribute to changes in energy expenditure and lean body mass.

29-Dec-2011 4:00 PM EST
Schizophrenia Diagnosis Associated with Progressive Brain Changes Among Adolescents
JAMA - Journal of the American Medical Association

Adolescents diagnosed with schizophrenia and other psychoses appear to show greater decreases in gray matter volume and increases in cerebrospinal fluid in the frontal lobe compared to healthy adolescents without a diagnosis of psychosis, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

15-Dec-2011 5:45 PM EST
Findings Suggest That Severe Sepsis Can Lead to Impairment of Immune System
JAMA - Journal of the American Medical Association

An analysis of lung and spleen tissue from patients who died of sepsis revealed certain biochemical, cellular and histological findings that were consistent with immunosuppression, according to a study in the December 21 issue of JAMA.

15-Dec-2011 5:45 PM EST
Hypertension Treatment Associated with Long-Term Improvement in Life Expectancy
JAMA - Journal of the American Medical Association

Patients with systolic hypertension who were treated with the diuretic chlorthalidone for 4.5 years as part of a clinical trial had a significantly lower rate of death and a gain in life expectancy free from cardiovascular death about 20 years later compared to patients who received placebo, according to a study in the December 21 issue of JAMA.

15-Dec-2011 5:40 PM EST
Increase in Resting Heart Rate Over 10-Year Period Linked with Increased Risk of Heart Disease Death
JAMA - Journal of the American Medical Association

In a study that enrolled nearly 30,000 apparently healthy men and women, those who had an increase in their resting heart rate over a 10-year period had an increased risk of death from all causes and from ischemic heart disease, according to a study in the December 21 issue of JAMA.

15-Dec-2011 5:30 PM EST
Sleep Disorders Common Among Police Officers
JAMA - Journal of the American Medical Association

A survey of police officers indicated that about 40 percent have a sleep disorder, which was associated with an increased risk of adverse health, safety and performance outcomes, according to a study in the December 21 issue of JAMA.

4-Nov-2011 5:20 PM EDT
Surgical Procedure Does Not Appear to Reduce Risk of Subsequent Stroke After 'Mini-Stroke'
JAMA - Journal of the American Medical Association

Patients with thickening and blockage of the internal carotid artery (supplies blood to the brain) and hemodynamic cerebral ischemia (insufficient blood flow to the brain, sub-type of stroke) who had a surgical procedure performed to improve blood flow in the artery did not have a reduced rate of stroke after 2 years compared to similar patients who received medical therapy alone, according to a study in the Nov. 9 issue of JAMA.

4-Nov-2011 5:00 PM EDT
Cardiac Stress Imaging More Frequent Among Patients Whose Physicians Provide, Bill for Procedures
JAMA - Journal of the American Medical Association

Patients treated by physicians who billed for both technical (practice/equipment) and professional (supervision/ interpretation) components of nuclear and echocardiographic stress imaging tests were more likely to undergo such tests after coronary revascularization compared with patients of physicians who did not bill for these services, according to a study in the Nov. 9 issue of JAMA.

4-Nov-2011 5:00 PM EDT
Small, Preliminary Study Finds Abnormal Number of Neurons in Brains of Children with Autism
JAMA - Journal of the American Medical Association

In a small, preliminary study that included 13 male children, those with autism had an average 67 percent more prefrontal brain neurons and larger than average brain weight, than children without autism, according to a study in the Nov. 9 issue of JAMA.

4-Nov-2011 5:25 PM EDT
Banning Sugar-Sweetened Beverages in Schools Does Not Appear to Reduce Consumption Among Adolescents
JAMA - Journal of the American Medical Association

State policies banning all sugar-sweetened beverages in schools are associated with reduced in-school access and purchase of these beverages, however these policies are not associated with a reduction in overall consumption of sugar-sweetened beverages, according to a report published Online First by Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

4-Nov-2011 5:20 PM EDT
Neuromuscular Warm-Up Associated with Reduced Lower Extremity Injuries in Adolescent Female Athletes
JAMA - Journal of the American Medical Association

Integrating a coach-led neuromuscular warm-up prior to sports practice appeared to reduce the risk of lower extremity injuries in female high school soccer and basketball athletes, according to a report in the November issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

4-Nov-2011 5:15 PM EDT
Study Examines Racial and Ethnic Variations in Substance-Related Disorders Among Adolescents
JAMA - Journal of the American Medical Association

Substance use is widespread among adolescents in the United States, particularly among those of Native American, white, Hispanic and multiple race/ethnicity, and these groups are also disproportionally affected by substance-related disorders, according to a report in the November issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

4-Nov-2011 5:00 PM EDT
Web-Based Intervention Appears Ineffective for Preventing Weight Gain in Adolescents
JAMA - Journal of the American Medical Association

A web-based computer-tailored intervention aiming to increase physical activity, decrease sedentary behavior, and promote healthy eating among adolescents was not associated with positive long-term outcome measures, but may have positive short-term effects on eating behaviors, according to a report published Online First by Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

4-Nov-2011 4:00 PM EDT
Study Characterizes Epigenetic Signatures of Autism in Brain Tissue
JAMA - Journal of the American Medical Association

Neurons in the prefrontal cortex of individuals with autism show changes at numerous sites across the genome, according to a study being published Online First by the Archives of General Psychiatry, one of the JAMA/Archives journals.

4-Nov-2011 4:00 PM EDT
Study Finds Wide Variation in Best-Estimate Clinical Diagnosis of Autism Spectrum Disorders
JAMA - Journal of the American Medical Association

In a study conducted at 12 university-based research sites, there was wide variation in how best-estimate clinical diagnoses within the autism spectrum were assigned to individual children, according to a study being published Online First by the Archives of General Psychiatry, one of the JAMA/Archives journals.

4-Nov-2011 5:05 PM EDT
Study Identifies Factors Linked with Better Medication Response for Treatment of Juvenile Arthritis
JAMA - Journal of the American Medical Association

Among patients with juvenile idiopathic arthritis (JIA) who initiated treatment with the drug etanercept, one-third achieved an excellent response, and this response was associated with low measures of disability at study entry, younger age at the onset of JIA, and fewer disease-modifying antirheumatic drugs used before initiating etanercept, according to a study appearing in JAMA.

27-Oct-2011 5:30 PM EDT
Regimen May Improve Cell Transplantation Outcomes For Older Adults with Blood, Bone Marrow Cancers
JAMA - Journal of the American Medical Association

Older patients with advanced hematologic malignancies, such as leukemia and lymphoma, who received a conditioning regimen that included minimal-intensity radiation therapy prior to allogeneic (genetically different) hematopoietic cell transplantation (HCT; receipt of bone marrow or stem cells transplant) had survival and progression-free survival outcomes suggesting that this treatment approach may be a viable option for older patients with these malignancies, according to a study in the November 2 issue of JAMA.

27-Oct-2011 5:30 PM EDT
Recipients of Organ Transplants at Increased Risk For Broad Range of Cancers
JAMA - Journal of the American Medical Association

Patients who have received a solid organ transplant, such as kidney, liver, heart or lung, have an overall cancer risk that is double that of the general population, with an increased risk for many different types of malignancies, according to a study in the November 2 issue of JAMA.

27-Oct-2011 5:30 PM EDT
Low Levels of Alcohol Consumption Associated With Small Increased Risk of Breast Cancer
JAMA - Journal of the American Medical Association

Consumption of 3 to 6 alcoholic drinks per week is associated with a small increase in the risk of breast cancer, and consumption in both earlier and later adult life is also associated with an increased risk, according to a study in the November 2 issue of JAMA.

24-Oct-2011 2:00 PM EDT
Study Finds That Annual Screening with Chest X-Ray Does Not Reduce Rate of Lung Cancer Deaths
JAMA - Journal of the American Medical Association

In a trial that included more than 150,000 participants, those who underwent annual chest radiographic screening for up to 4 years did not have a significantly lower rate of death from lung cancer compared to participants who were not screened, according to a study in the November 2 issue of JAMA.

20-Oct-2011 2:35 PM EDT
CT Scans for Lung Cancer Screening May be Beneficial in Detecting COPD
JAMA - Journal of the American Medical Association

Among men who were current or former heavy smokers, undergoing lung cancer screening with computed tomography (CT) scanning identified a substantial proportion who had chronic obstructive pulmonary disease (COPD), suggesting that this method may be helpful as an additional tool in detecting COPD, according to a study in the October 26 issue of JAMA.

20-Oct-2011 2:30 PM EDT
Researchers Identify Factors Associated with Increased Risk of Blood Clot within Coronary Stent
JAMA - Journal of the American Medical Association

Patients with certain genes or specific factors related to use of the anti-clotting drug clopidogrel are more likely to experience a blood clot within a coronary stent shortly after placement, according to a study in the October 26 issue of JAMA.

21-Oct-2011 12:25 PM EDT
Study Evaluates Industry Payments to Orthopedic Surgeons
JAMA - Journal of the American Medical Association

An analysis of financial payments made by orthopedic device manufacturers to orthopedic surgeons shows that the patterns of payments from 2007 to 2010 appear to be complex with a reduction in the total number of payments and the total amount of funds distributed after payment disclosure was required, as well as an increase in the proportion of consultants with academic affiliations, according to a report in the October 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

21-Oct-2011 12:30 PM EDT
Non-Targeted HIV Testing in Emergency Departments Identifies Only Few New Cases, French Study Finds
JAMA - Journal of the American Medical Association

Non-targeted HIV rapid test screening among emergency department patients in metropolitan Paris resulted in identifying only a few new HIV diagnoses, often at late stages and mostly among patients who are in a high-risk group, according to a study published Online First by the Archives of Internal Medicine.

21-Oct-2011 12:25 PM EDT
Probability Model Estimates Proportion of Women Who Survive Breast Cancer Detected Through Screening
JAMA - Journal of the American Medical Association

A model used to estimate breast cancer survival rates found that the probability that a woman with screen-detected breast cancer will avoid a breast cancer death because of screening mammography may be lower than previously thought, according to a report published Online First by Archives of Internal Medicine, one of the JAMA/Archives journals.

21-Oct-2011 12:25 PM EDT
Yoga and Stretching Exercises Beneficial for Chronic Low Back Pain
JAMA - Journal of the American Medical Association

Yoga classes were found to be more effective than a self-care book for patients with chronic low back pain at reducing symptoms and improving function, but they were not more effective than stretching classes, according to a study published Online First by the Archives of Internal Medicine.

14-Oct-2011 10:50 AM EDT
Sterilization Method for Hemodialysis Dialyzer Membrane Linked with Risk of Low Platelet Counts
JAMA - Journal of the American Medical Association

Patients who had undergone hemodialysis using dialyzers that had been sterilized with the use of electron beams were more likely to develop thrombocytopenia (an abnormally low platelet count in the blood, associated with increased risk of bleeding), according to a study in the October 19 issue of JAMA.



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