This is the first study to demonstrate active replication of HIV virus in a cell type other than immune T cells and which may help to predict patients at greatest risk for HIV dementia.
Patients who have high-risk non-melanoma skin carcinomas of the head and neck may benefit from concomitant radiotherapy and chemotherapy, according to a UNC-led study. Their study is the first to report on multiple patients with these skin carcinomas treated simultaneously with radio-and chemotherapy.
University of North Carolina at Chapel Hill researchers have revealed the genetic underpinnings of cells – called Foxp3-expressing regulatory T cells or Tregs – that can prevent the immune response from turning cannibalistic.
This study of more than 50,000 adults ages 18 and older provides new molecular evidence that 11 DNA regions in the human genome have strong association with these diseases, including six regions not previously observed.
A new study, conducted in part at the University of North Carolina at Chapel Hill, finds that a 24-week triple medication treatment course for hepatitis C is just as effective as a 48-week regimen.
A new study by UNC researchers finds that an inexpensive set of infection control measures could potentially save many thousands of lives and billions of dollars.
Scientists at the University of North Carolina at Chapel Hill School of Medicine have devised a gene therapy cocktail that has the potential to treat some inherited diseases associated with “misfolded” proteins.
The award, given by the Rural Sociological Society, honors Dr.Joanne Jordan of the University of North Carolina at Chapel Hill for her work over the last 20 years in the Johnston County Osteoarthritis Project.
A UNC-led international study shows that among Kenyan men, circumcision is associated with a lower prevalence of human papillomavirus-associated precancerous lesions of the penis.
A molecular technique originally developed at the University of North Carolina at Chapel Hill has taken one step closer to becoming a treatment for the devastating genetic disease Duchenne muscular dystrophy.
Women who have breastfeeding difficulties in the first two weeks after giving birth are more likely to suffer postpartum depression two months later compared to women without such difficulties, according to a new study by UNC researchers.
Scientists at the University of North Carolina at Chapel Hill schools of medicine and pharmacy have been awarded a $3 million federal grant to develop and test a new generation of treatments aimed at preventing sexual transmission of HIV to uninfected individuals. This remains the most common cause of HIV infection worldwide.
Researchers at the University of North Carolina at Chapel Hill have been awarded a $32 million, five-year federal grant to develop ways to cure people with HIV by purging the virus hiding in the immune systems of patients taking antiretroviral therapy. Tackling this latent virus is considered key to a cure for AIDS.
Researchers in the University of North Carolina at Chapel Hill/North Carolina State University joint biomedical engineering department will be at the Kennedy Space Center for the last space shuttle launch of the NASA program as Atlantis departs for its final mission into Earth’s orbit.
Using a combination of genetic engineering and laser technology, researchers at the University of North Carolina at Chapel Hill have manipulated brain wiring responsible for reward-seeking behaviors, such as drug addiction.
Having a history of eating disorders or abuse may increase a woman’s risk for developing depression during and after pregnancy, according to new research from the University of North Carolina at Chapel Hill. The finding could influence how doctors screen patients during prenatal visits.
Researchers at the University of North Carolina at Chapel Hill School of Medicine have shown in an animal study that transplantation of adult stem cells enriched with a bone-regenerating hormone can help mend bone fractures that are not healing properly.
A study by UNC researchers finds surprising evidence that the pelvis continues to grow wider even after people stop growing taller. This increase in pelvic width may account for a significant portion of the weight gain that many people experience as they get older.
A team of researchers, including a number from the University of North Carolina at Chapel Hill School of Medicine, have pinpointed regions of the genome that contribute to the debilitating lung disease that is the hallmark of cystic fibrosis.
A new study from the University of North Carolina at Chapel Hill School of Medicine further validates the use of humanized BLT mice in the fight to block HIV transmission.
World-leading HIV expert and study leader, Myron Cohen, M.D., available to speak on landmark findings.
A new study of U.S. veterans ages 70 and older finds that the healthiest get the most benefit from current colon cancer screening methods. However, for many less healthy veterans the burdens of screening may outweigh the benefits.
Below are a selection of oral presentations given at this year’s DDW by University of North Carolina at Chapel Hill School of Medicine researchers.
Researchers at the University of North Carolina at Chapel Hill School of Medicine, after isolating normal stem cells that form the developing placenta, have given them the same properties of stem cells associated with an aggressive type of breast cancer.
A study by UNC researchers finds that children with autism who had enlarged brains at age 2 continued to have enlarged brains at ages 4 and 5. However, this increased brain growth did not continue beyond age 2, and the changes detected at age 2 were due to overgrowth prior to that time point.
Unintentional overdose deaths in teens and adults have reached epidemic proportions in the U.S.
As World Autism Awareness Day, April 2, approaches, scientists at the UNC School of Medicine hunt for new treatments and interventions for the disorder.
Bryan L. Roth, PhD, the Michael J. Hooker Distinguished Professor of Pharmacology in the University of North Carolina at Chapel Hill School of Medicine, has received the PhRMA Foundation Award in Excellence in Pharmacology/Toxicology.
UNC researchers have discovered that a molecule called Wnt1 can improve the function of endothelial progenitor cells, increasing the blood flow to organs that previously had been cut off from the circulation.
A new commentary by four internationally prominent genetic medicine and bioethics experts cautions against the dangers of inflated expectations for genomics research and offers ways to avoid it while still realizing “the true – and considerable – promise of the genomic revolution.”
A team of UNC-Chapel Hill researchers has been awarded a $3.6 million grant to develop computer models that will allow physicians to predict which treatments will work best in children with upper airway problems.
Researchers at the University of North Carolina at Chapel Hill have pinpointed a crucial function for a key player in the development of the nervous system.
New research from the University of North Carolina at Chapel Hill School of Medicine describes a key molecular mechanism in nerve fibers that ensures the rapid conductance of nervous system impulses.
Syndicated radio host Delilah will help raise money and awareness for North Carolina Children's Hospital at UNC-Chapel Hill and other Together for Kids hospitals nationwide. This partnership was announced Jan. 25.
A new study shows that a test of biomarkers for DNA methylation is technically feasible and could aid in earlier, more precise diagnosis of melanoma.
A team of researchers led by Channing Der, PhD, has made a discovery about how the Ras oncogene chooses a signaling pathway and how the consequences of that choice play out in cellular development – a key issue in cancer.
Researchers investigating a genetic mutation in brain cancer and leukemia patients have discovered how one cancer metabolite battles another normal metabolite to contribute cancer development. Helping the “good guys” win that battle could yield new approaches for treatment.
Researchers at the University of North Carolina at Chapel Hill have discovered a molecule that can make brain cells resistant to programmed cell death or apoptosis.
Dr. Anand V. Germanwala and Dr. Adam M. Zanation, have published a paper describing a surgery they performed that is believed to be the first reported clipping of a ruptured brain aneurysm through a patient's nose.
Researchers at the University of North Carolina at Chapel Hill have launched a new clinical trial to determine if estrogen replacement therapy may help prevent depression and cardiovascular illness in women between the ages of 45 and 55.
These results show that basal-like breast cancer is equally aggressive in African American and white women, and that African American women had worse outcomes no matter what kind of breast cancer they developed.
In the editorial, the UNC researchers explain the excitement about this new class of drugs and the importance of this trial. They also highlight the reasons that caution as well as enthusiasm is warranted.
An evaluation by UNC researchers concluded that fewer N.C. youths are taking up smoking, more public places have become smoke-free and more adults that smoke are quitting, thanks to tobacco prevention programs funded by the North Carolina Health and Wellness Trust Fund.
A new study finds that combining the newer diabetes drug exenatide with insulin provides better blood sugar control in patients with type 2 diabetes than insulin alone and helps promote weight loss.
Dr. Darren DeWalt, author of a JAMA editorial being released early online this week, is available for media interviews.
On Nov. 16, 2010, at the annual AHA meeting in Chicago, Arjun Deb, MD, was awarded the Louis N. and Arnold M. Katz Basic Science Research Prize for Young Investigators. Deb is an assistant professor of medicine and of cell and molecular physiology, and a member of the McAllister Heart Institute and the Lineberger Comprehensive Cancer Center.
New research led by scientists from the University of North Carolina at Chapel Hill School of Medicine and the University of California, Santa Barbara, describes new complexities in the close chemical combat waged among bacteria. The findings may have implications for human health and survival.
Researchers at the University of North Carolina at Chapel Hill School of Medicine have demonstrated that the gene mutated in cystic fibrosis not only controls traffic on the chloride highway, but also keeps the sodium highway from being overused.
Kelly Bruno, a second-year medical student at the University of North Carolina at Chapel Hill, is also an amputee who has completed three Ironman triathlons. But she is perhaps better known to many as "Kelly B.," one of the castaways on "Survivor: Nicaragua."
Common foot disorders such as flat feet, corns and bunions are more prevalent among African Americans than in whites, a new study by University of North Carolina at Chapel Hill researchers has found.
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