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A nationwide survey of people who were pregnant or trying to become pregnant found that overall 54 percent expressed interest in the RSV vaccine during pregnancy. Perceiving RSV as a serious illness in infants was the strongest predictor of likely vaccination during pregnancy. Likelihood to receive the RSV vaccine during pregnancy was also higher among parents with a child at home already. Findings were published in the journal Pediatrics.

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The lab of Yongchao C. Ma, PhD, at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago discovered a fundamental biological mechanism that could lead to new treatments for neurological diseases, such as spinal muscular atrophy (SMA) and autism, as well as different cancers.

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Mehul V. Raval, MD, MS, FACS, FAAP, has been named the Head of the Division of Pediatric Surgery at Ann & Robert H. Lurie Children’s Hospital of Chicago. After an extensive national search and reviewing several highly accomplished applicants, Dr. Raval’s expertise, translational research, leadership experience and dedication to Lurie Children’s set him apart. He will hold the Orvar Swenson Founders' Board Chair in Pediatric Surgery.

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On March 27, 2024, Ann & Robert H. Lurie Children’s Hospital of Chicago treated its first patient with ELEVIDYS (delandistrogene moxeparvovec-rokl), the first gene therapy for Duchenne muscular dystrophy – a rare, genetic disease characterized by progressive muscle damage and weakness.

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A new study found that during the pandemic pediatric emergency departments (EDs) saw more children and adolescents who needed a psychiatric admission, as well as an increase in severe conditions, such as bipolar disorder, schizophrenia and substance use disorders.

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Four children who acquired HIV in utero have remained free of detectable HIV for more than one year, according to new findings that were presented today, March 6, at the Conference on Retroviruses and Opportunistic Infections (CROI) in Denver, Colo. The study is part of ongoing, multinational research led in part by scientists from Northwestern University Feinberg School of Medicine and Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago.

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Scientists from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University succeeded in regenerating fully functional urinary bladder tissue in a long-term study utilizing a non-human primate model.

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Clinician-scientists from Ann & Robert H. Lurie Children’s Hospital of Chicago were among a diverse, international group of experts tasked by the Society of Critical Care Medicine (SCCM) with developing and validating new data-based criteria for sepsis in children. Sepsis is a major public heath burden, claiming the lives of over 3.3 million children worldwide every year. The new pediatric sepsis criteria – called the Phoenix criteria – follow the paradigm shift in the recent adult criteria that define sepsis as severe response to infection involving organ dysfunction, as opposed to an earlier focus on systemic inflammation.

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Prenatal diagnosis of congenital heart defects – the most common birth defects in the United States – is associated with improved outcomes. Despite its importance, however, overall prevalence of prenatal diagnosis is low (12-50 percent). A recent multi-center study surveyed caretakers of infants who received congenital heart surgery in the Chicago area and found that social determinants or influencers of health constitute significant barriers to prenatal diagnosis from the patients’ perspective.

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An unexpectedly high percentage of children, who were born with HIV and started treatment within 48 hours of life, exhibit biomarkers by 2 years of age that may make them eligible to test for medication-free remission, according to a multinational study published in Lancet HIV.

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The lab of Yongchao C. Ma, PhD, at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago uncovered a novel mechanism that leads to motor neuron degeneration in spinal muscular atrophy (SMA).

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A new study offers a novel look at the scope of the youth mental health crisis across the United States – in 2019-2020, more than 1 in 10 kids who were brought to the hospital by ambulance had a behavioral health emergency. Out of these behavioral health emergencies, 85 percent were in 12-17-year-olds. Findings were published in the journal Academic Emergency Medicine.

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Pediatric Emergency Department (ED) visits for firearm injuries doubled during the pandemic compared to earlier trends, according to a multicenter study published in the journal Pediatrics.

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A survey from Ann & Robert H. Lurie Children’s Hospital of Chicago found that 40 percent of parents who worked remotely during the pandemic reported higher parenting stress compared with only 27 percent of parents who worked onsite.

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A study from Ann & Robert H. Lurie Children’s Hospital of Chicago demonstrated that Botulinum toxin (Botox) injected in the pylorus (sphincter where the stomach exits into the small intestine) during endoscopy improves chronic nausea and vomiting in children who have a disorder of gut-brain interaction (DGBI).

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Jeffrey Raskin, MS, MD, a neurosurgeon at Ann & Robert H. Lurie Children’s Hospital of Chicago, performed the first ever computer-guided radiofrequency ablation to decrease excessive muscle tone (called hypertonia) in a child with cerebral palsy.

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Researchers from Ann & Robert H. Lurie Children’s Hospital of Chicago and colleagues reported for the first time that a genetic biomarker may be able to help predict the severity of food allergy reactions.

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The Texas A&M University schools of nursing and public health have jointly been awarded a five-year, $7.4 million grant from the U.S. Department of Health and Human Services (HHS) to promote positive adolescent health behavior in one of the country’s largest metropolitan areas. The project is a collaboration with Ann & Robert H. Lurie Children’s Hospital of Chicago.

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Discovery from the lab of Youyang Zhao, PhD, from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago offers promising treatment approaches for acute respiratory distress syndrome (ARDS) in the elderly that can be caused by severe COVID-19, pneumonia, flu or sepsis.

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A study from Ann & Robert H. Lurie Children’s Hospital of Chicago has shown that prenatal diagnosis, or diagnosis before a baby is born, is associated with earlier surgery for babies with congenital heart defects, the most common birth defects affecting nearly 1% of all live births. The association was demonstrated for critical defects (when heart surgery is required before the infant leaves the hospital) and certain types of noncritical defects, which constitute about 75% of all congenital heart defects.