Delivery of antioxidants to liver mitochondria
Hokkaido UniversityA new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.
A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.
The seas surrounding the Arctic are important fisheries and ecological regions; they are also among the areas most affected by climate change. The effects of warming waters and loss of sea ice on the biodiversity of these waters, and hence their ecology, is still not fully understood.
Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.
Synthetic hydrogels were shown to provide an effective scaffold for neuronal tissue growth in areas of brain damage, providing a possible approach for brain tissue reconstruction.
Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig’s disease and Stephen Hawking’s disease, is a neurodegenerative disease that results in the gradual loss of control over the muscles in the body.
Data stored in ice cores dating back 55 years bring new insight into atmospheric levels of a molecule that can significantly affect weather and climate.
A new analysis of seismic data recorded after the massively violent eruption of the underwater volcano Hunga Tonga-Hunga Ha’apai, on January 15, 2022, has revealed new and useful information on the sequence of events.
Researchers at Hokkaido University have revealed the effects of high pathogenicity avian influenza virus infection on an Ezo red fox and a Japanese raccoon dog, linking their infection to a recorded die-off of crows.
New insights into the opposing actions of serotonin-producing nerve fibres in mice could lead to drugs for treating addictions and major depression.
Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.
Training individuals to inhibit imitation of others increases empathy and allows them to recognize facial expressions in others regardless of their situations.
Theory-guided development of an easier, more versatile process for synthesizing unsymmetric ligands provides new avenues of exploration in transitional metal catalysis.
Plastic sheets coated with an Eu3+ film that converts UV light to red light were able to accelerate growth of vegetal plants and trees.
Chronic heart failure causes the cell’s powerhouses to dysfunction, in part due to overconsumption of an important intermediary compound in energy production.
Scientists have uncovered new details of how ice forming below the ocean surface in Antarctica provides cold dense water that sinks to the seabed in an important aspect of global water circulation.
Researchers from Hokkaido University and Toppan have developed a method to detect build-up of amyloid β in the brain, a characteristic of Alzheimer’s disease, from biomarkers in blood samples.
SARS-CoV-2, the virus that causes COVID-19, is an airborne disease transmitted via aerosols, which are spread from the oral and nasal cavities—the mouth and the nose.
Only satellites were watching when the world's fourth-largest proglacial lake suddenly drained in 2020. Hokkaido University researchers now uncovered the event and analysed the cause—the collapse of a sediment bump at the outlet of the lake.
Hokkaido University researchers find a new way of producing the industrially important propylene that is more energy efficient than existing approaches—and in the process turns carbon dioxide into another usable resource.
Researchers have used the mathematical equations of chaos theory to analyse the data from long-term monitoring of an electronically tagged narwhal.
Two novel hypotheses have been proposed that address the “two-fold cost of sex”: one of the biggest enigmas in the evolution of sexual reproduction.
Computer simulations are most often used as a guide, so chemists can more efficiently work out the exact details of a general reaction idea they have in mind — much like a compass helps guide an explorer efficiently to a destination on their map.
The phrase “All roads lead to Rome” captures in five words how important roads are for important cities.
Waste heat is a very promising source of energy conservation and reuse, by means of converting this heat into electricity—a process called thermoelectric conversion.
Researchers have discovered argon trapped in air-hydrate crystals in ice cores, which can be used to reconstruct past temperature changes and climate shifts.
Scientists have developed a model that predicts six tropical fish species will expand into northern parts of Japan as sea temperatures rise.
Wastewater-based epidemiological tracking of COVID-19 in the Tokyo 2020 Olympic and Paralympic village showed that SARS-CoV-2 was present in areas without diagnosed individuals.
Within meteorites, the magnetic fields associated with the particles that make up the object can act as a historical record.
Scientists have developed a rapid, highly accurate test to detect antibodies against the spike protein of SARS-CoV-2 in human serum, opening a new avenue for understanding the full extent of the pandemic and evaluating the effectiveness of vaccines.
Scientists show that an ocean-bottom seismometer deployed close to the calving front of a glacier in Greenland can detect continuous seismic radiation from a glacier sliding, reminiscent of a slow earthquake.
Coral insights into 1,000 years of seasonal changes in the Arabian Sea warn of significant impacts caused by global warming.
Scientists from Hokkaido University have discovered a novel defensive response to SARS-CoV-2 that involves the viral pattern recognition receptor RIG-I.
Scientists from Hokkaido University have used species survey and climate data to identify two marine biodiversity refugia in the Eastern Bering Sea - regions where species richness, community stability and climate stability are high.
A 2020 explosion in Lebanon's port city of Beirut led to a southward-bound, high-velocity atmospheric wave that rivaled ones generated by volcanic eruptions.
Computational models suggest that melting water originating in the deep interior of Greenland could flow the entire length of a subglacial valley and exit at Petermann Fjord, along the northern coast of the island. Updating ice sheet models with this open valley could provide additional insight for future climate change predictions.
Scientists have estimated that the age of an individual does not indicate how likely they are to be infected by SARS-CoV-2. However, development of symptoms, progression of the disease, and mortality are age-dependent.
Climate warming will alter marine community compositions as species are expected to shift poleward, significantly impacting the Arctic marine ecosystem.
Testing self-collected saliva samples could offer an easy and effective mass testing approach for detecting asymptomatic COVID-19.
An international consortium of researchers under the aegis of CMIP6 has calculated new estimates for the melting of Earth's ice sheets due to greenhouse gas emissions and its impact on sea levels, showing that the ice sheets could together contribute more than 40 cm by the end of 2100.
Scientists review macrophage activation syndrome -- a feature of the cytokine storm that kills patients with severe cases of COVID-19, as well as possible treatments.
Ice is melting at a surprisingly fast rate underneath Shirase Glacier Tongue in East Antarctica due to the continuing influx of warm seawater into the Lützow-Holm Bay.
A group of researchers have demonstrated that, from seven methods commonly used to test for viruses in untreated wastewater, an adsorption-extraction technique can most efficiently detect SARS-CoV-2. This gives us another tool to detect the presence and spread of the COVID-19 pandemic.
Scientists have found the interstellar organic matter could produce an abundant supply of water by heating, suggesting that organic matter could be the source of terrestrial water.
Scientists at Hokkaido University and collaborators have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance, resulting in poor prognosis of cancer patients.
A re-analysis of dinosaur skulls from northern Alaska suggests they belong to a genus that lived over a broad latitudinal range extending into the Arctic.
A protein that helps colorectal cancer cells spread to other parts of the body could be an effective treatment target.
Fossil coral records provide new evidence that frequent winter shamals, or dust storms, and a prolonged cold winter season contributed to the collapse of the ancient Akkadian Empire in Mesopotamia.
An experiment shows that one of the basic units of life -- nucleobases -- could have originated within giant gas clouds interspersed between the stars.
Persistent abnormally hot weather can cause negative impacts on human health, agriculture, and natural environments.
The rise in temperature and precipitation levels in summer in northern Japan has negatively affected the growth of conifers and resulted in their gradual decline