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Case Western Reserve University (CWRU) and its primary affiliate, University Hospitals Case Medical Center (UHCMC), recently announced that they will establish a Global Advanced Imaging Innovation Center in partnership with Philips Healthcare. The Center, to be based at UHCMC, is funded in part by a $5 million Ohio Third Frontier Commission grant to CWRU. Philips Healthcare will invest an additional $33.4 million in the Center.

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Surviving heart failure calls for lifestyle changes, taking medications and following doctor’s orders. Researchers from Case Western Reserve University, Kent State University, Summa Health System and University Hospitals Case Medical Center will find out if subtle cognitive impairments cause the adherence problems in heart failure cases.

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Anna Maria Mandalakas, MD, MSEpi, associate professor of Pediatrics, Global Health and Epidemiology & Biostatistics at Case Western Reserve University School of Medicine, has been selected by the J. William Fulbright Foreign Scholarship Board to receive a 2010 U.S. Fulbright Scholarship.

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Survey data compiled by a national technology transfer organization shows Case Western Reserve University continuing a leadership role among Ohio universities, hospitals and research institutes, and the outlook for ongoing strong performance is bright.

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New research found documents that prove Alfred L. Rives was the designer and lead builder of the Cabin John Bridge, for 40 years the longest single-span stone bridge in the world and the longest in the U.S. still today. Rives was denied credit after joining the Confederacy.

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Case Western Reserve University once again ranked as one of the best medical schools in the nation in the annual U.S.News & World Report “America’s Best Graduate Schools” rankings. Of the 126 national medical schools surveyed by the magazine, Case Western Reserve’s School of Medicine ranked 20th in research – and overall, an improvement of 5 places over last year’s ranking. This ranking once again placed it highest among Ohio medical schools.

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Stan Brock, the humanitarian who has been delivering free health care worldwide through his nonprofit organization Remote Area Medical (RAM) for 25 years, will be recognized as the recipient of the 2010 Inamori Ethics Prize, awarded by the Inamori International Center for Ethics and Excellence at Case Western Reserve University.

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Case Western Reserve University (CWRU) School of Medicine has received $7,942,500 million in federal stimulus funds from the Ohio Health Information Partnership (OHIP), the state designated entity for health information exchange development. The funding will position CWRU School of Medicine as a regional extension center (REC) which allows it to help 1,765 health care providers in Lorain, Cuyahoga, Lake, Geauga and Ashtabula counties advance the use of health information technology (HIT) in their practices.

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For millions of Americans with Type-2 diabetes and inject insulin to control diabetes (with onset typically in adulthood) the associated risk of cancer is of increasing concern. Studies have demonstrated that obesity and excess insulin – whether naturally produced by the body or injected in synthetic form – are associated with an increased incidence of some common cancers.

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Case Western Reserve University School of Medicine researchers have identified a major indicator of two deadly diseases of the heart and blood vessels: heart failure and aortic aneurysm. The absence of the Kruppel-like Factor 15 (KLF15), when combined with stress, leads to both heart failure and aortic aneurysms.

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Many moms who start off breastfeeding ponder baby bottle issues, as they have to return to work or need to spend several hours away from the baby.

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In a paradigm changing discovery, Plasmodium vivax (P. vivax) malaria has been identified in a population historically thought to be resistant to the disease, those who do not express the Duffy blood group protein on their red blood cells, according to researchers from Case Western Reserve University School of Medicine, Pasteur Institute, and the Madagascar Ministry of Health.

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There is typically a shortage of donated blood in the United States, and research at Case Western Reserve University is looking for ways of improving the life-saving supply.

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One year post-surgery, patients who underwent Descemet’s stripping automated endothelial keratoplasty (DSAEK) experienced greater cell loss overall compared to those who underwent penetrating keratoplasty (PKP), according to a new analysis of data collected from the Cornea Donor Study (CDS) Investigator Group’s 2008 SMAS.

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Ardiem Medical Inc. has obtained a non-exclusive license to make and sell neuromodulation devices based on intellectual property developed at Case Western Reserve University’s Department of Biomedical Engineering and the Functional Electrical Stimulation (FES) Center in Cleveland.

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Case Western Reserve University School of Medicine has been awarded six Department of Defense (DOD) Congressionally Directed Medical Research Programs (CDMRP) grants for innovative medical research. The grants, totaling nearly $2.8 million, will advance research in the field of breast cancer.

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New analysis of data from the 2008 Specular Microscopy Ancillary Study (SMAS), a subset of the CDS, found that the preoperative donor cell count of endothelial cells, previously considered to be an important predictor of a successful transplant, did not correlate with graft success.

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Mark A. Smith, Ph.D., Professor of Pathology at Case Western Reserve University School of Medicine has been awarded the distinction American Association for the Advancement of Science (AAAS) Fellow. Election as a Fellow is an honor bestowed upon AAAS members by their peers.

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Case Western Reserve University has granted an 18-month, exclusive option to startup Thermalin Diabetes Inc. regarding a portfolio of insulin analogs. The company must reach certain milestones in order to exercise its option to obtain an exclusive license on therapies designed to help patients with diabetes.

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John L. Johnson, M.D., Professor of Medicine at Case Western Reserve University School of Medicine and pulmonologist at University Hospitals Case Medical Center has been awarded a 10 year, $19.7M contract from the U.S. Centers for Disease Control and Prevention (CDC) as an international clinical trials site for the Tuberculosis Trials Consortium (TBTC).

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Case Western Reserve University School of Medicine has received a $14.7 million, nine-year contract from the National Institutes of Health to be one of five institutions to lead a trial to determine if lowering systolic blood pressure in hypertensive patients, without diabetes, to below the currently recommended level can reduce the incidence of cardiovascular and kidney disease and slow cognitive decline.

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Some business-thinking Doctor of Nursing Practice grads from Case Western Reserve University’s Frances Payne Bolton School of Nursing (FPB) will share their entrepreneurial knowledge during “Global Nursing Education: The Role of the Professional Doctorate.” The conference takes place Friday, October 16, at Case Western Reserve University.

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Researchers at Case Western Reserve University School of Medicine have been awarded a $1.57 million renewal grant from the National Eye Institute (NEI) of the National Institutes of Health to continue their study of corneal infections, specifically, bacterial keratitis, associated with contact lens wear.

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While infant and toddler brains are rapidly developing, a window of opportunity exists to reduce the impact of autism, which now affects one of every 150 children born in the United States. Gerald Mahoney, director of the Center on Interventions for Children and Families at the Mandel School of Applied Social Sciences of Case Western Reserve University, received a three-year, $780,000 grant from the National Institutes of Child Health and Human Development

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An National Institutes of Health (NIH) Transformative R01 Program grant for $4.9 million has been awarded to Case Western Reserve University School of Medicine. The five-year grant will fund research to identify patients’ inborn genetic susceptibility to the development of colon cancer metastasis.

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Mad cow disease is caused by the accumulation of an abnormal protein, the prion, in the brain of an affected patient. Outside of the brain, very little is known about prions. Case Western Reserve University School of Medicine, researchers have, for the first time, identified the prion as a biomarker for pancreatic cancer.

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A team of researchers from Case Western Reserve University School of Medicine have solved the mystery of why some children are more susceptible to malaria infection and anemia. These novel findings suggest that some children who are exposed to Plasmodium falciparum (P. falciparum) malaria before birth become tolerant to the malaria parasites, or their soluble products.

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Yiping Han, associate professor at the Case Western Reserve University School of Dental Medicine, aims to understand how to build roadblocks for a common bacterium that's harmless in a mother's mouth but can turn deadly when it reaches an unborn child.

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Seniors are sharpening their recall and other mental processes at The Brain Emporium, a community center program opened and run by Case Western Reserve University Psychologist T.J. McCallum. McCallum and graduate students custom design a regimen of computer games and programs for each individual's needs and wants.

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Researchers from Case Western Reserve University School of Medicine identified a novel link between ITCH, a gene known to regulate inflammation in the body and NOD2, a gene which causes the majority of genetic Crohn's Disease diagnoses. ITCH, when malfunctioning, causes widespread inflammatory diseases, including inflammatory bowel disease, gastritis, uncontrolled skin inflammation, and pulmonary pneumonitis.

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The Center for Stem Cell & Regenerative Medicine, comprised of Case Western Reserve University, Cleveland Clinic, University Hospitals, and Athersys, Inc. has received $5 million from Ohio's Third Frontier Commission under the Research Commercialization Program. The funding will help support new and innovative stem cell technologies including two commercial, four emerging and three pilot projects. This funding will be matched by each of the projects to create a $10 million grant benefiting stem cell and regenerative medicine in Ohio.

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A team of researchers led by Amy G. Hise, M.D., M.P.H., assistant professor at the Center for Global Health and Diseases, Case Western Reserve University School of Medicine, is the first to discover how the body fights off oral yeast infections caused by the most common human fungal pathogen, Candida.

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Mitchell Machtay, MD, Named Chairman of Radiation Oncology at University Hospitals Case Medical Center and Case Western Reserve University School of Medicine.

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People, suffering from gum disease and a severe form of rheumatoid arthritis, reduced their arthritic pain, number of swollen joints and the degree of morning stiffness when they cured their dental problems, report researchers from the Case Western Reserve University School of Dental Medicine and University Hospitals of Cleveland.

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Pediatricians now have a new and simple way to diagnose a serious problem facing our nation's children, hypertension "“ thanks to David Kaelber, M.D., Ph.D., M.P.H., MetroHealth System pediatrician, internist, and chief medical informatics officer and Case Western Reserve University School of Medicine researcher and faculty member.

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A new study finds that individuals who have low expression of the "Celebrex gene," 15-PGDH, are actually resistant to Celebrex treatment when used to prevent colon cancer.

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As a Case Western Reserve University alumnus, Dr. David Satcher, the 16th Surgeon General of the United States, will return to his alma mater to inspire a new class of graduates when he delivers the 2009 Commencement speech on Sunday, May 17, at 9:30 a.m. in Veale Convocation, Athletic and Recreation Center on the Case Western Reserve campus.

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Change the lighting; improve your health. Researchers from Case Western Reserve University, the Louis Stokes Cleveland Veterans Affairs Medical Center, Rensselaer Polytechnic Institute's Lighting Research Center and GE Consumer & Industrial have begun testing in a long-term care facility where daylight is not readily available.

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The Center for Proteomics and Bioinformatics and the Case Center for AIDS Research at Case Western Reserve University School of Medicine have a received a $989,108 grant from the National Institute of Drug Abuse (NIDA) at the National Institute of Health (NIH), with the ability to receive a total of $3,007,946 by 2011.

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The new study cautions adoptive parents not to rely solely on vaccination records when gauging their internationally adopted children's immunizations. Researchers examined immunization records in international adoptees and found that the records may not accurately predict if a child is protected from disease "“ even with what appears to be a valid written immunization record, a child may lack immunization.

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Case Western Reserve University School of Medicine researchers are the first to discover a form of synaptic memory in the olfactory bulb, the part of the brain that processes the sense of smell.

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Qing Yin Zheng, M.D., assistant professor of Otolaryngology-Head and Neck Surgery and Genetics at the Case Western Reserve University School of Medicine, and member of the Case Comprehensive Cancer Center, has been awarded a five year $1.66 million grant from the National Institutes of Health (NIH) Research Project Grant Program (R01) to explore the impact of several molecular pathways on inner ear dysfunction in Ushers syndrome.

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A multidisciplinary team of investigators from Case Western Reserve University, Duke University and University of Massachusetts, Amherst, created an environment where magnetic particles suspended within a specialized liquid solution acted like molecular sheep dogs by nudging free-floating human cells to form chains in response to external magnetic fields.

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Three Case Western Reserve University School of Medicine researchers were listed in the Top 100 Alzheimer's disease investigators according to a study conducted by Collexis Holdings Inc. published in the Journal of Alzheimer's Disease. The Top 100 list was released in the journal's March edition (Volume 16, Issue 3).

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Case Western Reserve University School of Medicine Department of Ophthalmology and Visual Sciences has been awarded an unrestricted grant along with three individual awards that could total up to $1 million by the Research to Prevent Blindness (RPB) Foundation.

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The Cleveland Museum of Natural History, Case Western Reserve University School of Medicine and its Department of Environmental Health Sciences have partnered to establish a Center for Environmental Health and Human Ecology. Museum and School of Medicine leaders recently signed a memorandum of understanding to create the new center.

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For people with diabetes who have a visual impairment, reading the small print on a syringe and getting the right dose can be difficult or impossible. Another method of delivering insulin, popular in Europe and Asia but less so in the United States, is the insulin pen. The fountain pen-like device is a self-contained applicator with 300 units of insulin. What has currently interested NIH/Case Western Reserve postdoctoral fellow Ann Williams in the delivery of insulin is the disclaimer several drug companies have placed on insulin pen devices, warning against use by the visually impaired.

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Researchers at Case Western Reserve University, led by Gary Landreth, a professor of neurosciences and neurology at the School of Medicine, have pulled together a number of recent findings that link a common genetic pathway with a number of human syndromes and a newly-recognized genetic form of autism.

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Case Western Reserve University has been awarded a two-year contract for $1.33 million from the National Institutes of Health (NIH) to fund a pilot project that will expand informatics support for investigators, providing improved collaboration and sharing of information between investigators from multiple disciplines.

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James W. Kazura, M.D., Professor of International Health and Medicine, and Director, Center for Global Health and Diseases at Case Western Reserve University School of Medicine has been selected to join a group of 25 experts in global health research who will advocate for greater U.S. investment in global health research.