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In a study with powerful implications for people needing organ and tissue transplants, researchers at Dana-Farber Cancer Institute and Harvard Medical School have devised a new technique that may make transplants available to nearly everyone with a partially matched donor.

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In a pair of studies that promise to rewrite scientists' understanding of genetic "tripwires" that kill cells before they become fully cancerous, researchers at Dana-Farber Cancer Institute have found that the same system that protects against cancer can, in some circumstances, actually promote cells on the road toward malignancy.

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Scientists at Dana-Farber Cancer Institute and Duke University Medical Center have uncovered a new portion of the circuitry that controls the natural death of cells, they published in the April 23 issue of Science.

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In a study that points the way to a new form of cancer therapy, researchers at Dana-Farber Cancer Institute and Harvard Medical School report that a drug commonly used to treat diabetes has caused tumor cells to shift to a slower-growing, less-menacing state in patients with a rare type of cancer.

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In a study that confirms warnings issued by researchers four years ago, the same researchers now report that both infant and adult monkeys vaccinated with a live, weakened form of an HIV-like virus have developed AIDS from the vaccine virus itself.

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The "International Conference on the Prevention and Early Diagnosis of Lung Cancer" today release an unanimously agreed upon statement calling for the need to address screening and early detection of lung cancer.

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In an unexpected spin-off of cancer research that began more than a decade ago, scientists at Dana-Farber Cancer Institute have succeeded in reducing atherosclerosis - hardening of the arteries - by 80 percent in mice by blocking a gene in mice that is virtually identical to one in humans.

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In experiments with mice, researchers at Dana-Farber Cancer Institute and Children's Hospital (Boston) have used a naturally occurring protein to thwart one of the most common -- and potentially lethal -- complications associated with bone marrow transplants.

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Researchers at Dana-Farber Cancer Institute and Columbia University have obtained the first detailed, three-dimensional picture of the lock-and-key mechanism by which HIV-1 binds to blood cells -- a milestone in the effort to develop AIDS vaccines that are effective against many strains of the virus.