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Diagnosing Alzheimer's disease can be a complex and time-consuming process, requiring evaluations ranging from brain scans to cognitive and lab tests to reviews of medical history and symptoms. Simpler and faster ways to diagnose the disease are urgently needed. Researchers at Albert Einstein College of Medicine have been awarded a five-year, $4.2 million National Institutes of Health (NIH) grant to detect behavioral markers for Alzheimer’s that are present early in the course of the disease, before it can be clinically diagnosed. Results could help scientists identify people at risk for Alzheimer’s and related problems, such as falls, and lead to new preventive strategies.

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To help address the rising tide of Alzheimer’s disease nationwide, researchers at Albert Einstein College of Medicine in collaboration with faculty at Pennsylvania State University and other institutions, have received a five-year, $32 million grant from the National Institutes of Health (NIH) to support the ongoing Einstein Aging Study (EAS), which focuses on both normal aging and the special challenges of Alzheimer’s disease, and other dementias. EAS was established at Einstein in 1980 and has been continuously funded by the NIH.

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New York State Health Commissioner Mary T. Bassett, M.D., M.P.H., will present the keynote address at Albert Einstein College of Medicine’s 2022 commencement. The ceremony will take place on Wednesday, May 25, 2022, at Carnegie Hall in New York City.

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Cigarette smoking is overwhelmingly the main cause of lung cancer, yet only a minority of smokers develop the disease. A study led by scientists at Albert Einstein College of Medicine and published online today in Nature Genetics suggests that some smokers may have robust mechanisms that protect them from lung cancer by limiting mutations. The findings could help identify those smokers who face an increased risk for the disease and therefore warrant especially close monitoring.

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The National Cancer Institute-designated Albert Einstein Cancer Center (AECC) has announced the appointment of three faculty members to key leadership positions, reflecting the center’s commitment to basic science, translational, and clinical research and its core principles of diversity, equity, and inclusion.

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Revving up a process that slows down as we age may protect against atherosclerosis, a major cause of heart attacks and strokes. In findings published online today in Proceedings of the National Academy of Sciences (PNAS), scientists at Albert Einstein College of Medicine led by Ana Maria Cuervo, M.D., Ph.D., successfully minimized artery-narrowing plaque in mice that would otherwise develop those lesions. The researchers did so by boosting chaperone-mediated autophagy (CMA), a cellular housekeeping process that Dr. Cuervo discovered in 1993 and named in 2000.

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Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%. The paper describing the findings published online today in Science Translational Medicine.

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In a demonstration of research excellence and entrepreneurial vision, faculty at Albert Einstein College of Medicine have secured two of the five 2022 XSeed Awards, which provide $100,000 in funding for each winning team to advance promising basic science findings that have startup potential. The theme of this year’s competition was neurodegeneration, with proposals offering novel approaches to address key questions about the pathogenesis, progression, diagnosis, or treatment of neurodegenerative diseases.

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A research team led by scientists at Albert Einstein College of Medicine has devised a novel and highly promising strategy for overcoming a key cause of cancer deaths: the ability of cancer cells to thrive in the face of chemotherapy drugs designed to destroy them.

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Prisons and jails have been fertile ground for COVID-19 outbreaks, leading to millions of cases in the United States. Individuals released from these facilities often transition to other congregate settings, such as homeless shelters and group homes, where COVID-19 infections can continue to spread. Now, Albert Einstein College of Medicine and Montefiore Health System have been awarded a five-year, $3.4 million grant from the National Institutes of Health (NIH) to test a program aimed at reducing SARS- CoV-2 transmission among people recently released from incarceration.

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Albert Einstein College of Medicine and Montefiore Health System have been awarded a three-year, $447,000 grant to grow their addiction medicine education and training programs for medical students and residents. The grant, from the Substance Abuse and Mental Health Services Administration (SAMHSA), will fund a new curriculum focused on the diagnosis and care for people with opioid use disorder (OUD), including guidance about medications for addiction treatment (MAT), particularly buprenorphine.

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Albert Einstein College of Medicine and Montefiore Health System have been awarded a National Institutes of Health (NIH) grant to establish a multidisciplinary research center focused on treatments for people with both chronic pain and opioid use disorder (OUD).

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The Bronx is home to more than 27,000 people living with HIV, the majority of whom are Black or Hispanic men. People living with HIV have an increased risk for depression and substance use, which in turn can make adhering to daily antiviral treatments difficult, negatively impacting both quality of life and overall health. Now, the National Institutes of Health (NIH) has awarded researchers at Albert Einstein College of Medicine and Montefiore Health System two five-year grants totaling $7.6 million to study the structural and chemical changes in the brain of people living with HIV, depression, and cannabis use disorder.

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As part of a recently launched international phase 3 clinical trial, Montefiore Health System and Albert Einstein College of Medicine are investigating whether the Merck antiviral pill, molnupiravir, now approved in Britain for treating COVID-19, can prevent COVID-19 in unvaccinated individuals living with people who have contracted the disease. Montefiore-Einstein is the first and only New York State site for the trial and was selected due to its diverse patient population and expertise in clinical trials of COVID-19 and other infectious diseases.

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Ulrich G. Steidl, M.D., Ph.D., co-director of the Blood Cancer Institute and associate director of basic science at the Albert Einstein Cancer Center (AECC), has received a prestigious Outstanding Investigator Award from the National Cancer Institute (NCI).

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Armed with a novel strategy they developed for bolstering the body’s immune response, scientists at Albert Einstein College of Medicine have successfully suppressed HIV infections in mice—offering a path to a functional cure for HIV and other chronic viral infections. Their findings were published today in the Journal of Clinical Investigation.

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Albert Einstein College of Medicine has received a five-year, $4 million grant from the National Institutes of Health (NIH) to support the New York Regional Center for Diabetes Translation Research (NY-CDTR). One of only seven such centers in the country and the only one in the Northeast, the NY-CDTR promotes collaboration and research on effective strategies to improve diabetes prevention, care, and self-management, with an emphasis on health equity.

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The Bronx has been hit disproportionally by COVID-19. For caregivers in the borough, the pandemic has caused unprecedented psychological distress. In addition to existing health disparities, these families now face greater financial insecurity and challenges related to their school-aged children.

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A new community-based approach to helping children manage their asthma symptoms will launch in up to 40 public, charter, and parochial schools across the Bronx, and enroll 416 students aged 4-12 years old. The five-year study, titled Evaluation of the Asthma Management Program to Promote Activity for Students in Schools (Asthma-PASS), is supported by a $4.2 million grant from the National Institutes of Health to Albert Einstein College of Medicine and the Children’s Hospital at Montefiore (CHAM).