University of Maryland School of Medicine researchers developed a technique in laboratory animals to consistently and reproducibly open the blood-brain barrier. Their paper essentially provides a roadmap for other researchers to develop and test new therapies for brain diseases.
A new study in mice from University of Maryland School of Medicine researchers showed that an unhealthy vaginal microbiome in pregnant mothers in combination with an unhealthy diet contributed to increased pup deaths and altered development in the surviving babies.
In a first-of-its-kind surgery, a 57-year-old patient with terminal heart disease received a successful transplant of a genetically-modified pig heart and is still doing well three days later. It was the only currently available option for the patient.
Research Shows Vaccine Has 90 Percent Efficacy at Preventing Infections; Moderate to Severe Disease Occurred Only in Placebo Recipients
University of Maryland School of Medicine (UMSOM) researchers, working with scientists from the Regeneron Genetics Center (RGC), discovered a new gene variant associated with lower levels of heart-damaging LDL cholesterol and a blood clotting protein called fibrinogen that appears to significantly lower a person’s risk of heart disease.
University of Maryland Medicine, comprised of the University of Maryland Medical System (UMMS) and the University of Maryland School of Medicine (UMSOM) has announced that it will end the use of a long-standing clinical standard that factors a patient’s race into the diagnosis of chronic kidney disease (CKD).
Using data generated from patients and mice with genetic mutation for the disorder Usher syndrome, researchers from the University of Maryland School of Medicine and the National Institutes of Health documented the natural history of vision impairment in patients and identified the cell mechanism behind progressive vision loss.
In a newly published study, researchers at the University of Maryland School of Medicine have detected antibodies primarily made in response to infections in the mucous membranes — in such areas as the lungs, intestines, or vagina — in study participants with malaria.
Researchers have long known that air pollution can increase the risk of certain health conditions, but they did not know the exact mechanism. Now, University of Maryland School of Medicine (UMSOM) researchers have shown how air pollution reduces sperm count in mice by causing brain inflammation.
Seven-year Javits Neuroscience Investigator Award Given to Dr. Crino for Cutting-Edge Research.
A team led by researchers at the University of Maryland School of Medicine has published an online interactive atlas representing the changes in the levels of RNA made in the different cell types of ears of mice, after damage due to loud noise.
Eating yogurt containing a particular strain of a well-studied probiotic appears to protect against harmful changes in the gut microbiome that are associated with antibiotic administration.
New Partnership Will Create Digital Infrastructure to Support Statewide ‘All of Maryland’ Study to Learn More About How Genes and Other Factors Affect Health
Those Admitted to the ICU for Care Are at Significantly Greater Risk of Dying if They Have Little Social Support
About 300,000 to 400,000 fetuses per year from mothers with diabetes develop neural tube defects—when the tissue that eventually forms the brain and spinal cord fails to form properly—which can lead to miscarriage or profound disability.
Have you ever met someone you instantly liked, or at other times, someone who you knew immediately that you did not want to be friends with, although you did not know why? Now, a new study from the University of Maryland School of Medicine (UMSOM) suggests that there may be a biological basis behind this instantaneous compatibility reaction.
Rural regions in the U.S. have been disproportionately affected by the opioid epidemic, while also having the fewest number of programs to treat opioid use disorder.
David McDuff, MD, Director of the Sports Psychiatry Program at the University of Maryland School of Medicine is available for media interviews today to discuss the stress Olympic athletes are under during the most important competitions of their lives.
University of Maryland School of Medicine and University of Vermont researchers have shown how the brain communicates to blood vessels when in need of energy, and how these blood vessels respond by relaxing or constricting to direct blood flow to specific brain regions.
University of Maryland School of Medicine (UMSOM) Professor of Diagnostic Radiology & Nuclear Medicine, Linda Chang, MD, MS, received the National Institute on Drug Abuse (NIDA) 2021 Avant Garde Award (DP1) for HIV/AIDS and Substance Use Disorder Research — a National Institutes of Health (NIH) Director’s Pioneer Award.
With the National Eye Institute reporting that about 11 million older adults in the U.S. endure a condition that leads to progressive blindness, known as age-related macular degeneration, University of Maryland School of Medicine (UMSOM) researchers are starting to understand what goes wrong in the disease, in order to develop new therapies to treat it.
University of Maryland School of Medicine (UMSOM) researchers identified a new gene that may be linked to certain neurodevelopmental disorders and intellectual disabilities.
University of Maryland School of Medicine (UMSOM) researchers have shown that psilocybin—the active chemical in “magic mushrooms”— still works its antidepressant-like actions, at least in mice, even when the psychedelic experience is blocked.
Using laboratory-grown roundworms as well as human and mouse eye tissue, University of Maryland School of Medicine (UMSOM) researchers have identified a new potential mechanism for age-related macular degeneration—the leading cause of blindness among older adults.
Mr. Brown’s Gift Memorializes his Daughter, Esther Ann Brown Adler, and Establishes the Thomas M. Scalea, MD Endowed Distinguished Professorship in Trauma Surgery
Medical school and healthcare industry leaders warn that a drastic decline in pediatric vaccinations in the United States, poses a great risk of serious illnesses in the midst of the COVID-19 pandemic
Scientists from the University of Maryland School of Medicine (UMSOM) developed an experimental diagnostic test for COVID-19 that can visually detect the presence of the virus in 10 minutes. It uses a simple assay containing plasmonic gold nanoparticles to detect a color change when the virus is present. The test does not require the use of any advanced laboratory techniques, such as those commonly used to amplify DNA, for analysis. The authors published their work last week in the American Chemical Society’s nanotechnology journal ACS Nano.
Researchers at the University of Maryland School of Medicine (UMSOM) have begun testing the effectiveness of hydroxychloroquine as a therapy to prevent infection and symptoms in individuals who have been exposed to COVID-19-positive individuals. The trial is significant because it focuses on preventing COVID-19 and does not involve individuals who are ill with infection but rather healthy individuals who have been exposed.
– University of Maryland School of Medicine (UMSOM) Dean E. Albert Reece, MD, PhD, MBA, announced today the launch of a large-scale COVID-19 Testing Initiative that will significantly expand testing capability over the coming weeks, enabled by new funding of $2.5 million from the State of Maryland.
The Kids & COVID-19 Site includes important resources for practices, educational information for parents and other important resources for caregivers about issues impacting children.
– Over the past year, at least seven children have died from diseases including influenza while being detained by the U.S. Department of Homeland Security’s Customs and Border Protection (CBP) agency. Infectious disease experts at the University of Maryland School of Medicine (UMSOM) called for protections like influenza vaccinations to prevent serious outbreaks.
Researchers at the University of Maryland School of Medicine (UMSOM) found that the medical costs are substantially higher among older adults who go untreated for obstructive sleep apnea (OTA).
Diarrheal diseases are a leading cause of death for young children, accounting for nine percent of all deaths worldwide in children under five years of age, with most occurring in children under two years of age. Now, researchers at the University of Maryland School of Medicine (UMSOM) found that even milder cases of diarrheal diseases can lead to death in young children.
University of Maryland School of Medicine (UMSOM) Dean, E. Albert Reece, MD, PhD, MBA, kicked off a celebration and recognition of longstanding Chair of the UMSOM’s Board of Visitors (BOV), Michael E. Cryor, President of The Cryor Group and recognized strategic counselor and public leader, for his distinguished service to the UMSOM for the past 10 years. At the celebration, Dean Reece announced that current UMSOM Board Member Cynthia L. Egan has been selected as the new Chair of the UMSOM Board.
Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella and enterotoxigenic Escherichia coli (ETEC), and researchers at the University of Maryland School of Medicine are testing a vaccine designed to offer protection against these serious pathogens.
Launch of centers to treat adults with neurodevelopmental disorders, such as autism. These are the first in the state of Maryland and a pioneering approach for treatment across the United States.
Kathleen M. Neuzil, MD, MPH, Director of the Center for Vaccine Development and Global Health (CVD) at the University of Maryland School of Medicine (UMSOM), has been elected as a member of the National Academy of Medicine (NAM), in recognition of her pivotal research that has informed and shaped global vaccine and public health policy.
The National Institute of Allergy and Infectious Diseases research contract is one of the largest ever awarded to UMSOM and includes an initial award of approximately $2.5 million to conduct clinical testing of influenza vaccines. Total funding over seven years could be as much as $201 million if all options are exercised in the NIAID contract.
The UM School of Medicine's Contract awarded by the National Institute of Allergy and Infectious Diseases could fund up to $201 Million in influenza research over seven years.
Each year more than 260,000 older Americans are hospitalized for hip fractures, a debilitating injury that can severely and permanently impact mobility. Researchers at the University of Maryland School of Medicine (UMSOM) studied two types of home-based interventions and discovered that these treatments are effective in helping individuals regain their ability to walk, but not enough to do every day functions like crossing the street.
Each year there are more than 200 million cases of malaria worldwide, a mosquito-borne disease caused by a parasite that brings on fever and body aches and, in some cases, more serious conditions such as coma and death. While the vast majority of these cases occur in sub-Saharan Africa and South Asia, the U.S. each year sees more than 1,500 cases, and currently there is limited access to an intravenously-administered (IV) drug needed for the more serious cases, according to a top malaria researcher at the University of Maryland School Medicine (UMSOM).
The vaginal microbiome is believed to protect women against Chlamydia trachomatis, the etiological agent of the most prevalent sexually transmitted infections (STIs) in developed countries.
The University of Maryland School of Medicine is awarded a $750,000 grant to establish a rural residency program to help ensure that there is a pipeline of general practitioners in rural Maryland Eastern Shore counties.
Neurodegenerative diseases like multiple sclerosis (MS) affect millions of people worldwide and occur when parts of the nervous system lose function over time. Researchers at the University of Maryland School of Medicine (UMSOM) have discovered that a type of skin-related stem cell could be used to help regenerate myelin sheaths, a vital part of the nervous system linked to neurodegenerative disorders.
The Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) was awarded $17.5 million from the National Institute of Allergy and Infectious Diseases (NIAID) to fund the IGS Genome Center for Infectious Diseases (GCID) for another five years.
Spontaneous preterm birth (sPTB), defined as birth before 37 weeks of gestation, and the related complications, are the largest contributors to infant death in the United States and worldwide, according to the World Health Organization. Researchers at the University of Maryland School of Medicine (UMSOM) have discovered that bacteria and innate immune factors in a woman’s birth canal and cervix may increase the risk of spontaneous preterm birth or provide protection against such births.
Each year there are nearly 11 million cases of typhoid, a disease that is spread through contaminated food, drink and water. Researchers at the University of Maryland School of Medicine are leading an international consortium that is studying the impact of a typhoid conjugate vaccine (TCV) in an effort to accelerate introduction of the vaccine in countries in sub-Saharan Africa and Asia where there is a high burden of typhoid.
Researchers at the University of Maryland School of Medicine have discovered a mechanism for how androgens -- male sex steroids -- sculpt brain development. The research, conducted by Margaret M. McCarthy, Ph.D., who Chairs the Department of Pharmacology, could ultimately help researchers understand behavioral development differences between males and females.
University of Maryland School of Medicine (UMSOM) Dean E. Albert Reece, MD, PhD, MBA, announced today that Claire M. Fraser, PhD, a pioneer in the field of microbial genomics, who is the Dean’s Endowed Professor, Department of Medicine, and Director of the Institute for Genome Sciences (IGS), has been chosen as president-elect of the American Association for the Advancement of Science (AAAS).
Researchers at the University of Maryland School of Medicine’s (UMSOM) Maryland Psychiatric Center (MPRC) and Institute for Genome Sciences (IGS), along with researchers at the University of Maryland School of Pharmacy (UMSOP), have been awarded a collaborative five-year $1.78 million grant to study the brain-to-gut connection in schizophrenia
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