New research from the University of Maryland School of Medicine suggests that the system for choosing transplant recipients in chronic obstructive pulmonary disease (COPD) may underestimate how long a person might survive without a lung transplant and therefore, may mislead clinicians.
A new study finds that the Harpoon Mitral Valve Repair System, an image-guided device based on technology developed at the University of Maryland School of Medicine, is safe and effective.
University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.
Researchers at the University of Maryland School of Medicine have found that a new, collaborative treatment model for seriously ill heart patients with breathing difficulties results in better care and lower costs.
University of Maryland School of Medicine researchers report that a device that removes toxins from the blood can also effectively provide a bridge to liver transplantation or buy time for a traumatically injured liver to heal, suggesting broader uses for the device than previously thought.
The April 2015 civil unrest associated with Freddie Gray’s death while in police custody caused a significant spike of stress in mothers of young children living in affected neighborhoods, according to new research from the University of Maryland School of Medicine (UM SOM). The research, conducted before, during and after the period of civil unrest, found that the number of mothers with depressive symptoms increased from an average of 21% before the incident to an average of 31% during the acute period, spiking to 50% in August 2015. Mothers also reported concerns about disruptions in daily routines such as eating, sleeping and shopping, all of which can undermine maternal wellbeing and negatively affect parenting behaviors and subsequently, child development.
Research at the University of Maryland School of Medicine, conducted in a Pennsylvania Amish community where virtually no women smoke, finds effects of secondhand smoke differ between men and women.
The University of Maryland Medical Center (UMMC) is now offering a simple genetic test to patients who receive heart stents to determine whether they have a genetic deficiency that affects how they respond to a common drug to prevent blood clots. Patients are typically given the medication, clopidogrel, to prevent cardiovascular events after having a stent placed in a coronary artery to treat a blockage.
Researchers at the University of Maryland School of Medicine (UM SOM) and the Interdisciplinary Stem Cell Institute (ISCI) at the University of Miami Miller School of Medicine have begun testing to see whether adult stem cells derived from bone marrow benefit children with the congenital heart defect hypoplastic left heart syndrome (HLHS).
Patients with advanced malignant pleural mesothelioma (MPM) treated with a combination of surgery to remove the cancer but save their lung, plus photodynamic therapy and chemotherapy, had a median survival of nearly three years, with a subset of patients living longer than seven years, according to new research published in the Annals of Thoracic Surgery.
Researchers have discovered a novel mechanism in a combination drug therapy that shows potential as a new approach for treating acute myeloid leukemia (AML) and many other cancers. When combined, these agents cause interactions that significantly disrupt cancer cells’ ability to survive DNA damage, according to a preclinical study published today in the journal Cancer Cell.
Treatment with MRI-guided focused ultrasound significantly improves tremors and quality of life in patients with essential tremor (ET), the most common movement disorder, according to a study published in the August 25 issue of the New England Journal of Medicine. Researchers at the University of Maryland School of Medicine (UM SOM), were among an international group of investigators studying this new noninvasive treatment, which was recently approved by the U.S. Food and Drug Administration (FDA), based on this research.
Researchers investigating a novel device to repair the mitral valve report 100 percent procedural success in a first-in-humans, safety and performance study. The device, deployed while the heart is beating, avoids open-heart surgery, automates a key part of the valve repair process, simplifies the procedure and reduces operating room time.
Malaria is one of the world’s deadliest diseases: it infects hundreds of millions of people every year, and kills about half a million, most of them under five years of age. There is no vaccine. Now, researchers at the University of Maryland School of Medicine are testing a malaria vaccine that has shown success in early tests.
In a first-of-its-kind procedure in the United States, a patient was able to avoid dialysis when surgeons simultaneously removed two diseased kidneys and also transplanted a kidney from a living donor – all as part of a 28-person paired kidney exchange
A batch of muffins, made with a special recipe formulated by the U.S. Department of Agriculture, yielded unexpected health benefits in patients with metabolic syndrome during a first-of-its-kind clinical study at the University of Maryland School of Medicine.
The University of Maryland Marlene and Stewart Greenebaum Cancer Center has been awarded the National Cancer Institute’s highest designation as a Comprehensive Cancer Center. The prestigious distinction recognizes the cancer center’s high caliber of scientific leadership and robust programs in basic, clinical and population science research, placing it in the top tier of cancer centers nationwide. The new name of the center is the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC).
A new study shows for the first time that HDL’s heart disease protection depends on the levels of two other blood fats or lipids associated with heart disease. If these fats are not within normal ranges, even a high HDL may not be protective.
A panel of sleep and brain injury specialists recommends specific steps to test and develop sleep-related treatments to improve the outcome of mild traumatic brain injury. The recommendations appear online ahead of print in the journal Neurotherapeutics.
A novel unit to care for critically ill patients significantly speeds access to specialized care, according to a new study by physician scientists at the University of Maryland School of Medicine and the University of Maryland Medical Center.
After more than a decade of research and development, researchers in the Department of Radiation Oncology at the University of Maryland School of Medicine will begin enrolling patients in the first clinical trial of GammaPod,™ a new high-precision, image-guided radiation therapy system specifically designed to treat early-stage breast cancer.
University of Maryland Medicine and its Center for Metabolic Imaging and Image-Guided Therapeutics has begun to use MRI-guided focused ultrasound on a deep structure within the brain related to Parkinson’s disease – the globus pallidus.
A group of epidemiologists and infection prevention specialists led by Daniel Morgan, MD, MS, an associate professor of Epidemiology & Public Health at the University of Maryland School of Medicine, reviewed current practice and existing literature on the use of contact precautions for MRSA and VRE to build a framework for decision-making based on all available evidence.
In recent years, immunotherapy has emerged as a promising treatment for certain cancers. Now this strategy, which uses patients’ own immune cells, genetically engineered to target tumors, has shown significant success against multiple myeloma, a cancer of the plasma cells that is largely incurable. The results appeared in a study published online today in Nature Medicine.
A new study has identified promising compounds that could successfully treat depression in less than 24 hours while minimizing side effects. The compounds could offer significant advantages over current antidepressant medications.
As the South Korean MERS outbreak continues, researchers have discovered and validated two therapeutics that show early promise in preventing and treating the disease, which can cause severe respiratory symptoms, and has a death rate of 40 percent.
The flu virus can be lethal. But what is often just as dangerous is the body’s own reaction to the invader. Now, a University of Maryland School of Medicine researcher has identified a “decoy” molecule that can rein in this runaway inflammatory response.
New research has led to FDA approval of the use of a drug to treat the effects of radiation exposure following a nuclear incident. The drug, Neupogen, is the first ever approved for the treatment of acute radiation injury.
Tick-borne diseases are a major public health problem around the world. Now, just in time for spring and the explosion of ticks in forests, lawns and trails, a new study by researchers from China and the University of Maryland School of Medicine has uncovered a never-before-seen illness transmitted by ticks. It’s possible that the disease could be a “substantial health threat” to humans and animals in areas where the carrier tick is common, the authors say.
Five years ago the BP Deepwater Horizon oil platform exploded. The spill caused enormous environmental damage, but it also caused great stress among Gulf Coast residents. Even now, a significant percentage of people there continue to deal with anxiety, depression and other mental health issues, researchers say.
Every year, more than 120 million prescriptions are written worldwide for thiazide drugs, a group of salt-lowering medicines used to treat high blood pressure. These drugs are often very effective. But in some patients, they don't work. The reasons for this have remained a mystery. Now, a new study by researchers at the University of Maryland School of Medicine (UM SOM) has revealed a key mechanism for this failure.
A new guideline authored by Allan Krumholz, MD, a professor of neurology at the University of Maryland School of Medicine, found that administering an antiepileptic medication immediately after a first seizure reduces the risk of having another seizure within two years.
The gut bacteria Lactobacillus rhamnosus GG has a reputation as a helpful microbe. Now, researchers at the University of Maryland School of Medicine have come up with an explanation for why. It appears that the bacteria may boost the activity of other gut microbes.
University of Maryland School of Medicine Dean E. Albert Reece, MD, PhD, MBA, announced today that the School of Medicine (UM SOM) plans to establish a major new Institute for Global Health (IGH), bringing together decades of UM SOM research, treatment and vaccine development around the world, and expanding the School’s platform as the premier, leading center for global health research, treatment and prevention. The new Institute will focus on vaccine development and malaria research, and will house the UM SOM’s reconfigured Center for Vaccine Development (CVD) as well as a newly-formed Center for Malaria Research (CMR).
During prenatal development, the brains of most animals, including humans, develop specifically male or female characteristics. But scientists have known little about the details of how this differentiation occurs. Now, a new study by researchers at the University of Maryland School of Medicine has illuminated details about this process.
Carroll Hospital Center physicians will now have 24/7 remote access to the University of Maryland Medical Center’s Brain Attack Team through a new telemedicine service for stroke patients, the hospitals announced today.
University of Maryland School of Medicine (UM SOM) Dean E. Albert Reece, MD, PhD, MBA, and Jeffrey A. Rivest, MS, President and Chief Executive Officer of University of Maryland Medical Center (UMMC), today announced the official launch of a new “Program in Lung Healing,” that will further the School’s position as a national leader in research, education and clinical innovation for acute ailments of the lung and respiratory system.
Targeted biopsy using new fusion technology that combines magnetic resonance imaging (MRI) with ultrasound is more effective than standard biopsy in detecting high-risk prostate cancer, according to a large-scale study published today in JAMA.
Research published today found that the investigational drug patiromer decreased high potassium levels and maintained normal potassium levels in patients with chronic kidney disease. The results of a multicenter trial appear in the New England Journal of Medicine.
New research by scientists at the University of Maryland School of Medicine (UM SOM) and the Ottawa Heart Institute has uncovered a new pathway by which the brain uses an unusual steroid to control blood pressure.
Shyamasundaran Kottilil, MBBS, PhD, a world-renowned expert in infectious disease, has joined the faculty of the University of Maryland School of Medicine’s Institute of Human Virology as Co-Director of IHV’s Clinical Research Unit and Associate Director for Clinical Research.
The Center for Vaccine Development at the University of Maryland School of Medicine is leading an internationally-acclaimed consortium of scientists in an unprecedented multi-trial collaboration to test a potential vaccine that could help prevent the continuing spread of the deadly Ebola virus.
Today, the University of Maryland School of Medicine presented an update on the national implementation of the Affordable Care Act (ACA), focusing on the impact to poor and underserved communities and individuals. Congressman Elijah Cummings was the featured speaker for the event.
The Medical Alumni Association of the University of Maryland School of Medicine (SOM) along with notable national experts review the cause and end of life issues surrounding the death of one of the most prominent figures of the 20th Century: former First Lady and leading women’s and civil rights advocate Eleanor Roosevelt as part of the 21st Annual Historical Clinicopathological Conference.
Current protocols for matching donor hearts to recipients foster sex mismatching and heart size disparities, according to a first-of-its kind analysis by physicians at the University of Maryland School of Medicine. Matching by donor heart size may provide better outcomes for recipients.
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