Millions of pre-diabetic Americans may be at increased risk of future stroke, say researchers at the University of California, San Diego School of Medicine in a new meta-analysis of epidemiological studies, but the precise degree of that threat is confounded by differing medical definitions and factors that remain unknown or unmeasured.
On June 6, 2012, UC San Diego Health System was honored with an “A” Hospital Safety ScoreSM by The Leapfrog Group, an independent national nonprofit run by employers and other large purchasers of health benefits. U.S. hospitals were assigned an A, B, C, D, or F based on safety performance.
Researchers at the Stein Institute for Research on Aging at the University of California, San Diego have received a $4 million grant from the National Institute of Mental Health (NIMH), part of the National Institutes of Health, to study accelerated biological aging in schizophrenia.
Each year, approximately 8,000 Americans are bitten by venomous snakes. On average, 800 or so bites occur annually in California, home to an abundance of snake species, but only one family is native and venomous: rattlesnakes. In San Diego County, the number of rattlesnake bites is increasing as well as the toxicity of the attack.
An international team of researchers, led by scientists at the University of California, San Diego School of Medicine, suggest that inactivation of two specific genes related to the immune system may have conferred selected ancestors of modern humans with improved protection from some pathogenic bacterial strains, such as Escherichia coli K1 and Group B Streptococci, the leading causes of sepsis and meningitis in human fetuses, newborns and infants.
Five scientists from the University of California, San Diego and its School of Medicine have been awarded almost $12 million in new grants from the California Institute for Regenerative Medicine (CIRM) to conduct stem cell-based research into regenerating spinal cord injuries, repairing gene mutations that cause amyotrophic lateral sclerosis and finding new drugs to treat heart failure and Alzheimer’s disease.
Antimicrobial peptides (AMPs) are molecules produced in the skin to fend off infection-causing microbes. Vitamin D has been credited with a role in their production and in the body’s overall immune response, but scientists at the University of California, San Diego School of Medicine say a hormone previously associated only with maintaining calcium homeostasis and bone health is also critical, boosting AMP expression when dietary vitamin D levels are inadequate.
Research by a collaborative group of scientists from UC San Diego School of Medicine, UC San Francisco and Wake Forest School of Medicine has led to identification of an existing drug that is effective against Entamoeba histolytica. This parasite causes amebic dysentery and liver abscesses and results in the death of more than 70,000 people worldwide each year.
Each year, more than 10 million girls under the age of 18 marry, usually under force of local tradition and social custom. Almost half of these compulsory marriages occur in South Asia. A new study suggests that more than two decades of effort to eliminate the practice has produced mixed results.
Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently no reliable method for early detection or therapeutic intervention.
A clinical study of 30 adult patients with multiple sclerosis (MS) at the University of California, San Diego School of Medicine has shown that smoked cannabis may be an effective treatment for spasticity – a common and disabling symptom of this neurological disease.
Diabetes affects nearly 24 million people in the United States, most with Type 2 diabetes, a disease which is often coupled with obesity. Concerned by the increasing number of overweight Americans, nutrition experts with the UC San Diego School of Medicine are launching Take Charge, a research study analyzing the effectiveness of a commercial weight-loss program on participants with Type 2 diabetes who have a BMI of 25 – 45.
An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, report that significant numbers of myofibroblasts – cells that produce the fibrous scarring in chronic liver injury – revert to an inactive phenotype as the liver heals. The discovery in mouse models could ultimately help lead to new human therapies for reversing fibrosis in the liver, and in other organs like the lungs and kidneys.
On May 3, 2012, Rady Children’s Hospital-San Diego and the UC San Diego School of Medicine launched the Center for the Promotion of Maternal Health and Infant Development.
Invasive and costly tests commonly performed on women before surgery for stress urinary incontinence (SUI) may not be necessary, according to researchers at the University of California San Diego, School of Medicine and the Urinary Incontinence Treatment Network.
Catheryn Yashar, MD, radiation oncologist at UC San Diego Moores Cancer Center and a pioneer in breast brachytherapy is available to offer perspective on the effectiveness of breast brachytherapy – a shorter course of radiation treatment for breast cancer.
Paul S. Viviano has accepted the position as the new CEO of UC San Diego Health System and associate vice chancellor for Health Sciences. His appointment was approved by the UC Board of Regents, and will commence June 1, 2012.
Study finds overweight teens who are satisfied with their bodies are less depressed, less prone to unhealthy behaviors.
Smoking is a major public health issue and quitting is the single most important thing smokers can do to improve their health. In the 2012 edition of the prestigious Annual Review of Public Health, researchers at the University of California, San Diego School of Medicine have reviewed the landscape of smoking cessation over the past 20 years.
Jim Black is fighting the meanest, most aggressive, most common kind of brain tumor in the United States: recurrent glioblastoma multiforme (GBM). In the United States, each year, approximately 10,000 patients are affected by GBM. Now, a novel investigational device – available only at clinical trial sites – is offering new hope to these patients.
UC San Diego Moores Cancer Center researchers and surgeons are among the first in the nation to treat patients with recurrent brain cancer by directly injecting an investigational viral vector into their tumor. The treatment is being developed by a local San Diego Company, Tocagen Inc.
Steven Garfin, MD, chair of the Department of Orthopedic Surgery in the UC San Diego School of Medicine was named President of the International Society for the Advancement of Spine Surgery (ISASS) for 2012 to 2013.
According to the California Department of Motor Vehicles (CADMV), distracted driving is on the rise due to an increase in the use of cell phones and other electronic devices and the increasing importance of these devices in individuals’ lives. Studies have shown that phoning and driving increases the risk of crashes four-fold, with hands free and hand held devices equally dangerous. Texting increases this risk 8-16 times.
According to a new study, the neuron-killing pathology of Alzheimer’s disease (AD), which begins before clinical symptoms appear, requires the presence of both amyloid-beta (a-beta) plaque deposits and elevated levels of an altered protein called p-tau.
People with nonalcoholic fatty liver disease (NALFD) who consume alcohol in modest amounts – no more than one or two servings per day – are half as likely to develop hepatitis as non-drinkers with the same condition, reports a national team of scientists led by researchers at the University of California, San Diego School of Medicine.
UC San Diego Medical Center, located in Hillcrest, has been named one of the nation’s 100 Top Hospitals® by Thomson Reuters. Ranked among the country’s major teaching hospitals, the Medical Center was also one of twelve hospitals to receive the Everest Award. This award honors hospitals that have achieved both the highest current performance and the fastest long-term improvement over a five-year period in Reuter’s national benchmarking study.
Karl Y. Hostetler, MD, has been selected as the recipient of the 2012 Gertrude Elion Memorial Lecture Award by the International Society of Antiviral Research. Hostetler is a professor of medicine in the Divisions of Infectious Diseases and Endocrinology at the UC San Diego School of Medicine.
Susan Ferro-Novick, PhD, professor in the Department of Cellular and Molecular Medicine at the University of California, San Diego School of Medicine, and Herbert Levine, PhD, professor in the UC San Diego Department of Physics, have been elected to the American Academy of Arts and Sciences.
Scott M. Lippman, MD, chair of Thoracic/Head and Neck Medical Oncology at The University of Texas (UT) MD Anderson Cancer Center, has accepted the position of director of Moores Cancer Center at the University of California, San Diego, beginning May 1, 2012.
UC San Diego Moores Cancer Center expert available to discuss controversial topic of breast brachytherapy.
On Monday, April 9, Santiago Horgan, MD, chief of minimally invasive surgery at UC San Diego Health System implanted the new FDA-approved LINX device in a 29-year old patient suffering from gastroesophageal reflux disease (GERD), a chronic digestive disease that can lead to severe inflammation, stricture, Barrett’s esophagus and esophageal cancer.
Researchers at the University of California, San Diego and Veterans Affairs San Diego Healthcare System have shown that elevated pulse pressure may increase the risk of cerebrovascular disease (CVD) in older adults with Alzheimer’s disease (AD).
The first atlas of the surface of the human brain based upon genetic information has been produced by a national team of scientists, led by researchers at the University of California, San Diego School of Medicine and the VA San Diego Healthcare System. The work is published in the March 30 issue of the journal Science.
Katherine Hepburn famously said of her slim physique: “What you see before you is the result of a lifetime of chocolate.” New evidence suggests she may have been right. Beatrice Golomb, MD, PhD, associate professor in the Department of Medicine at the University of California, San Diego, and colleagues present new findings that may overturn the major objection to regular chocolate consumption: that it makes people fat.
Repeated stress triggers the production and accumulation of insoluble tau protein aggregates inside the brain cells of mice, say researchers at the University of California, San Diego School of Medicine in a new study published in the March 26 Online Early Edition of the Proceedings of the National Academy of Sciences.
A study led by Eric Courchesne, PhD, director of the Autism Center of Excellence at the University of California, San Diego School of Medicine has, for the first time, identified in young autism patients genetic mechanisms involved in abnormal early brain development and overgrowth that occurs in the disorder. The findings suggest novel genetic and molecular targets that could lead to discoveries of new prevention strategies and treatment for the disorder
On Saturday, March 31, the UC San Diego Student-Run Free Clinic Project will host its annual fundraiser and awards ceremony. The event will be held at the UC San Diego Price Center Ballroom on the La Jolla campus. Funds raised during this event help provide free medical, dental, pharmacy, acupuncture, legal and social services to San Diego’s working poor and homeless. More than 2,000 San Diegans rely on its comprehensive integrative health services every year.
UC San Diego Moores Cancer Center has one of the first oncology practices in the nation to be recognized by the Quality Oncology Practice Initiative (QOPI®) Certification Program, an affiliate of the American Society of Clinical Oncology (ASCO). The QOPI® Certification Program is a new initiative to certify oncology practices that meet rigorous standards for high-quality cancer care.
A study by researchers at the University of California, San Diego School of Medicine and The University of Minnesota indicates that a parent’s weight change is a key contributor to the success of a child’s weight loss in family-based treatment of childhood obesity.
When you think of Botox injections, you probably think of getting rid of unwanted wrinkles around the eyes or forehead, but recently the FDA approved using the injections to help patients with neurological conditions who suffer from incontinence, or an overactive bladder.
Might the “Twinkie defense” have a scientific foundation after all? Researchers at the University of California, San Diego School of Medicine have shown – by each of a range of measures, in men and women of all ages, in Caucasians and minorities – that consumption of dietary trans fatty acids (dTFAs) is associated with irritability and aggression.
Patients seeking a weight-loss surgery that does not require an implanted device or permanent change to their anatomy, have a new clinical trial option at UC San Diego Health System. Santiago Horgan, MD, chief of minimally invasive surgery, and his team, now offer gastric plication, a novel surgery that folds the stomach into a smaller, more compact size.
Researchers at the California Teratogen Information Service (CTIS) Pregnancy Health Information Line, a statewide non-profit organization based at the University of California, San Diego School of Medicine, have found women exposed to certain antidepressants during pregnancy were significantly less likely to breastfeed their babies compared to unexposed women.
Researchers at the University of California, San Diego, the Medical University of South Carolina, the University of Cincinnati, and American Life Science Pharmaceuticals of San Diego have validated the protease cathepsin B (CatB) as a target for improving memory deficits and reducing the pathology of Alzheimer’s disease (AD) in an animal model representative of most AD patients.
A team of scientists at the University of California, San Diego Moores Cancer Center has identified a novel protein expressed by breast cancer cells – but not normal adult tissues – that could provide a new target for future anti-cancer drugs and treatments.
An innovative telemedicine program connecting neonatal specialists from UC San Diego Medical Center and Tri-City Medical Center’s Neonatal Intensive Care Unit (NICU) will allow experts to collaborate, diagnose and treat some of San Diego County’s tiniest, most difficult cases.
A small clinical trial led by researchers at UC San Diego School of Medicine and VA San Diego Healthcare System (VASDHS) found that patients with advanced heart failure and type 2 diabetes showed improved mitochondrial structure after three months of treatment with epicatechin-enriched cocoa. Epicatechin is a flavonoid found in dark chocolate.
UC San Diego Moores Cancer Center researchers and surgeons are among the first in the nation to treat patients with recurrent brain cancer by directly injecting an investigational viral vector into their tumor. The treatment is being developed by a local San Diego Company, Tocagen Inc.
UC San Diego Sulpizio Cardiovascular Center is now offering patients with atrial fibrillation the breakthrough benefits of heat energy, or radio frequency waves, to irreversibly alter heart tissue that triggers an abnormal heart rhythm or arrhythmia.
In a step toward deciphering the “splicing code” of the human genome, researchers at the University of California, San Diego School of Medicine have comprehensively analyzed six of the more highly expressed RNA binding proteins collectively known as heterogeneous nuclear ribonucleoparticle (hnRNP) proteins.
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