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Released: 19-Oct-2016 11:05 AM EDT
Gene Deletion Points Way to Flu Treatment
Houston Methodist

HOUSTON–(Oct. 19, 2016)–Researchers at Houston Methodist kept mice from getting the flu by removing a gene that regulates their immune system. According to a study recently published in Nature Immunology (online Oct. 3), mice missing the gene Trim29 eliminated human influenza virus within 48 hours, protecting them from infection.

Released: 12-Oct-2016 9:00 AM EDT
Houston Methodist Receives Nearly $4 Million From U.S. Defense Department to Combat Lethal Breast Cancer
Houston Methodist

HOUSTON-(Oct. 11, 2016)–Scientists at Houston Methodist received support from the U.S. Department of Defense (DoD) to reprogram immune cells to attack triple negative breast cancer, the most lethal form of the disease. The DoD awarded Rongfu Wang, Ph.D., director of the Center for Inflammation & Epigenetics at Houston Methodist Research Institute, $3 million to create a personalized vaccine that retrains cancer patients’ immune systems to safely target and eliminate breast tumors and spare normal tissue.

Released: 4-Oct-2016 8:05 AM EDT
Houston Methodist Receives $9 Million Federal Grant to Study Physics of Cancer Immunotherapy
Houston Methodist

Houston Methodist received $9 million from the National Cancer Institute to establish the Center for Immunotherapeutic Transport Oncophysics (CITO). CITO combines the studies of cancer immunology, nanotechnology and the physics of cancer biology. CITO will focus on using research information to design immunotherapies for breast and pancreatic cancers.

Released: 1-Aug-2016 1:05 PM EDT
Six-Way Kidney Swap
Houston Methodist

A stranger started a chain of events that led to six people receiving new kidneys at one institution.

Released: 24-Jun-2016 11:05 AM EDT
Texas A&M Planning to Create Medical School for Physician Engineers at Houston Methodist Hospital
Houston Methodist

Texas A&M University is planning to create an innovative engineering medical school at Houston Methodist Hospital to educate a new kind of doctor, pending appropriate approvals, who will invent transformational technology for health care, officials announced today.

6-May-2016 4:00 PM EDT
Common Antacid Linked to Accelerated Vascular Aging
Houston Methodist

Chronic use of some drugs for heartburn and gastroesophageal reflux (GERD) speeds up the aging of blood vessels, according to a published paper in Circulation Research (early online), an American Heart Association journal. This accelerated aging in humans could lead to increased cardiovascular disease, vascular dementia and renal failure.

Released: 5-May-2016 10:05 AM EDT
Men Also at Risk for Osteoporosis
Houston Methodist

Screening women for osteoporosis is now routine, however, when it comes to men, most are never screened and therefore suffer the consequences of the disease. In the U.S., nearly 1.5 million men over 65 have osteoporosis, and another 3.5 million men are at risk for developing the disease.

Released: 3-May-2016 8:00 AM EDT
Combining Pap and hrHPV Tests Could Drastically Reduce Cancer Miss Rates
Houston Methodist

Cytopathology researchers at Houston Methodist Hospital recently found that combining two diagnostic tests, Pap and high-risk human papillomavirus (hrHPV), dramatically decreased the chance of missing tumors and high-grade lesions by sevenfold.

Released: 6-Apr-2016 8:00 AM EDT
Center of Space Nanomedicine to work with CASIS on research aboard International Space Station
Houston Methodist

The Houston Methodist Research Institute’s newly created Center of Space Nanomedicine is working with the Center for the Advancement of Science in Space (CASIS) to send eight experiments to the International Space Station (ISS) over the next five years. The first experiment is set for launch this week.

Released: 4-Apr-2016 3:05 PM EDT
Common Allergy Medication Worsens Restless Leg Symptoms
Houston Methodist

Allergy season can be the worst time of year for people suffering with restless legs syndrome because popular over the counter medications can make symptoms much worse.

10-Mar-2016 10:00 AM EST
First Injectable Nanoparticle Generator Could Radically Transform Metastatic Breast Cancer Treatment
Houston Methodist

A team of investigators from Houston Methodist Research Institute may have transformed the treatment of metastatic triple negative breast cancer by creating the first drug to successfully eliminate lung metastases in mice. This landmark study appears today in Nature Biotechnology (early online edition).

Released: 8-Mar-2016 3:05 PM EST
Houston Methodist Neurosurgeon Removes Deep-Seated Thalamic and Brain Stem Cavernoma Through a Small Hole Successfully
Houston Methodist

Neurosurgeons at Houston Methodist Hospital report the successful treatment of deep-seated thalamic and brain stem cavernous angiomas in an upcoming article in the Journal of Neurosurgery (online March 8).

Released: 24-Feb-2016 11:05 AM EST
Dementia Treatment Delayed Due to Misdiagnosis
Houston Methodist

Many patients showing signs of dementia are quickly diagnosed with Alzheimer’s disease when they might actually suffer from frontotemporal dementia, delaying the appropriate treatment for them.

Released: 15-Feb-2016 2:05 PM EST
Using Umbilical Cord Blood to Speed Stroke Recovery
Houston Methodist

A new study will evaluate the use of whole umbilical cord blood to help the brain heal quicker after an ischemic stroke.

Released: 1-Feb-2016 1:05 PM EST
Cancer Patients Undergoing Chemotherapy Treatments Need to Have Heart Tested
Houston Methodist

Chemotherapy treatment is a necessary evil in the fight against most cancers and has prolonged life for millions of people. However, many cancer survivors suffer from an increased risk of heart problems related to the toxic effect some chemotherapy drugs have on the heart. The key is catching it early.

Released: 13-Jan-2016 12:05 PM EST
Finding a Living Donor Has Many Advantages for Patients Needing Kidney Transplant
Houston Methodist

More than 120,000 people are currently on the kidney transplant waiting list, some waiting anywhere from four to six years. Some of those people will die before the new kidney comes. Asking a family member or friend to donate a kidney might be difficult, but it has many advantages without affecting the donor.

Released: 3-Dec-2015 11:05 AM EST
Hanging the Holiday Lights Can Be Dangerous...for Your Feet
Houston Methodist

Many people fall off ladders when putting up holiday lights and severely damage their feet.

Released: 2-Dec-2015 11:05 AM EST
Computational Science Guru to Help Build Intelligent Operating Room of the Future
Houston Methodist

Marc Garbey, Ph.D., has joined Houston Methodist as scientific director of the Center for Computational Surgery. He was previously professor in the Department of Computer Science and the Department of Biology and Biochemistry at the University of Houston.

Released: 18-Nov-2015 11:00 AM EST
Extra Caffeine to Deal with Holiday Hustle and Bustle Might Be Masking a More Serious Problem
Houston Methodist

Many people will use caffeine to give them the extra boost they need to get everything done for the holiday season. However, a Houston Methodist internist says the need for more caffeine might be masking some serious sleep problems.

Released: 16-Nov-2015 11:05 AM EST
People Unaware of Fatty Liver Disease Could Make the Problem Worse with Holiday Overindulgence
Houston Methodist

Most of us will seriously overeat between Thanksgiving and New Year's Day. Those people walking around with non-alcoholic fatty liver disease could make the condition a lot worse, opening them up to serious diseases.

Released: 12-Nov-2015 10:05 AM EST
Personalizing Breast Cancer Subtype Detection Strategies
Houston Methodist

The National Cancer Institute awarded Houston Methodist investigator Randa El-Zein, M.B., Ch.B., Ph.D., a $2.8 million, five-year U01 grant to combine mammography features with blood-based biomarkers to more precisely predict a woman’s risk for breast cancer-specific subtypes.

Released: 9-Nov-2015 10:05 AM EST
Extra Holiday Stress Could Be Rough on a Woman’s Heart
Houston Methodist

Women put so much stress on themselves to make everything perfect for everything. This unnecessary pressure is not good for their heart health.

Released: 8-Oct-2015 10:05 AM EDT
Preventing Memory Loss Before Symptoms Appear
Houston Methodist

The Nantz National Alzheimer Center at Houston Methodist Hospital is part of a landmark clinical trial that looks at removing a key protein from the brain to prevent memory loss at least a decade before symptoms are noticed in healthy older adults.

Released: 28-Sep-2015 8:30 AM EDT
Prototype Lab in a Needle Could Make Real-Time, Mobile Laboratory Testing a Reality
Houston Methodist

Researchers at Houston Methodist, along with collaborators at two major Singapore institutions, have developed a lab in a needle device that could provide instant results to routine lab tests, accelerating treatment and diagnosis by days.

Released: 21-Sep-2015 9:00 AM EDT
Houston Methodist and Weill Cornell Receive Nearly $3 Million to Identify Lung Cancer Therapy Targets
Houston Methodist

The National Cancer Institute awarded Houston Methodist and Weill Cornell a multi-million dollar U01 grant to identify non-small cell lung cancer (NSCLC) therapy targets critical to identifying how tumors interact with surrounding cells.

Released: 22-Jul-2015 9:00 AM EDT
Brain Scientist Horner Joins Houston Methodist Neurological Institute
Houston Methodist

The Houston Methodist Neurological Institute's new Center for Neuroregenerative Medicine scientific director is Philip Horner, Ph.D., an expert on the use of stem cells to replace damaged brain and spinal cord tissue.

Released: 29-Jun-2015 2:05 PM EDT
Eat Healthy This Fourth of July
Houston Methodist

As the Fourth of July quickly approaches, people are preparing delicious side dishes to take to backyard cookouts. Unfortunately, these high-calorie side dishes can create a challenge for people who want to maintain or lose weight while still enjoying summer festivities.

8-Jun-2015 2:00 PM EDT
Heart Attack Risk Increases 16-21% with Use of Common Antacid
Houston Methodist

Adults who use proton pump inhibitors are between 16 and 21 percent more likely to experience a heart attack than people who don't use the commonly prescribed antacid drugs, according to a massive new study by Houston Methodist and Stanford University scientists.

Released: 4-Jun-2015 10:05 AM EDT
Houston Methodist Hospital, MD Anderson Cancer Center Teams Perform First Multi-Organ Transplant That Includes Skull and Scalp
Houston Methodist

Surgical teams from Houston Methodist Hospital and The University of Texas MD Anderson Cancer Center successfully transplanted, for the first time, a scalp and skull while performing kidney and pancreas transplants.

Released: 5-May-2015 10:00 AM EDT
Breast Cancer Vaccines May Work Better with Silicon Microparticles
Houston Methodist

The effectiveness of cancer vaccines could be dramatically boosted by first loading the cancer antigens into silicon microparticles, report scientists from Houston Methodist and two other institutions in an upcoming Cell Reports.

Released: 23-Apr-2015 11:00 AM EDT
Hundreds of Cancer Possibilities Arise From Common Skin Mole Mutation
Houston Methodist

A http:team of international scientists has identified hundreds of possible new genes in mice that could transform benign skin growths into deadly melanomas.

Released: 15-Apr-2015 1:30 PM EDT
New "4-D" Lung Cancer Model Could Quicken Discoveries
Houston Methodist

Researchers at Houston Methodist have invented a new, ex vivo lung cancer model that mimics the process of tumor progression. Tests of the model are published this month in The Annals of Thoracic Surgery (now online).

Released: 24-Mar-2015 9:00 AM EDT
Brain Tumor Cells Decimated by Mitochondrial "Smart Bomb"
Houston Methodist

An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has passed early tests in animal models and human tissue cultures, say Houston Methodist scientists.

Released: 23-Mar-2015 10:05 AM EDT
Small Clip Closes Off Leaking Mitral Valve in Patients Who Cannot Tolerate Open Surgery
Houston Methodist

A new clip helps older patients with mitral valve prolapse and who are not strong enough for open surgery.

6-Mar-2015 1:00 PM EST
"Bad" Fat Can Be Reformed with New Drug Target
Houston Methodist

Scientists say they know how white adipose cells -- often called "bad fat" -- can be converted into "good," brown adipose in mice using little more than a synthetic stand-in for thyroid hormone.

Released: 24-Feb-2015 5:00 PM EST
Common Hip Issue in Teens Misdiagnosed as Pulled Muscle
Houston Methodist

Rice University catcher, John Clay Reeves, felt pain in his groin after a collision at the plate with an opposing player. He thought he had pulled a muscle, but it turns out he was suffering from a common condition seen in teens and young adults known as hip impingement.

Released: 23-Feb-2015 10:00 AM EST
Magnetic Nanoparticles Could Stop Blood Clot-Caused Strokes
Houston Methodist

By loading magnetic nanoparticles with drugs and dressing them in biochemical camouflage, Houston Methodist researchers say they can destroy blood clots 100 to 1,000 times faster than a commonly used clot-busting technique.

   
Released: 17-Feb-2015 9:55 AM EST
7 Tips for Nurturing the Gut Microbiome
Houston Methodist

Increased awareness of the importance of digestive health has quickly turned into a multi-million dollar industry. According to Global Industry Analysts, the probiotics market is expected to exceed $29 billion by 2015 and expected to rise 7 percent a year over the next five years.

Released: 21-Nov-2014 10:00 AM EST
Holiday Overeating Can Be Big Problem for People with Type 2 Diabetes
Houston Methodist

Overindulging at a holiday party or two this season isn’t going make a big difference in someone’s health. But it could be a much different story for people with type 2 diabetes.



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