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Released: 10-Aug-2007 12:00 AM EDT
Investigators Uncover Intriguing Clues to Why Persistent Acid Reflux Sometimes Turns Into Cancer
UT Southwestern Medical Center

New research from scientists at UT Southwestern Medical Center and the Dallas Veterans Affairs Medical Center underscores the importance of preventing recurring acid reflux while also uncovering tantalizing clues on how typical acid reflux can turn potentially cancerous.

Released: 6-Aug-2007 12:00 AM EDT
Theory of Facial Aging Gets a Facelift from Researchers
UT Southwestern Medical Center

The longstanding idea that the entire human face ages uniformly is in need of a facelift, say researchers at UT Southwestern Medical Center who have found that multiple, distinct compartments of fat in the face age at different rates.

Released: 31-Jul-2007 12:00 AM EDT
Hydrogen Peroxide Could Cause Absorbable Sutures to Come Apart
UT Southwestern Medical Center

Cleaning absorbable sutures with hydrogen peroxide dramatically decreases their tensile strength, researchers from UT Southwestern Medical Center have found.

Released: 25-Jul-2007 11:20 AM EDT
Study Finds 30-Minute CPR Classes Just as Effective as Multi-hour Courses
UT Southwestern Medical Center

UT Southwestern Medical Center researchers have found that a user-friendly, 30-minute, video-based cardiopulmonary resuscitation training session is just as effective as the traditional three- to four-hour course in teaching basic life-saving techniques to laypersons.

23-Jul-2007 1:30 PM EDT
Drug Protects Brain Cells in Huntington’s Disease Model
UT Southwestern Medical Center

A drug used in some countries to treat the symptoms of Huntington's disease prevents death of brain cells in mice genetically engineered to mimic the hereditary condition, UT Southwestern Medical Center researchers have found.

Released: 9-Jul-2007 4:10 PM EDT
Physician Wins Prestigious Award from American Urological Association
UT Southwestern Medical Center

Dr. John McConnell, professor of urology and executive vice president for health system affairs at UT Southwestern Medical Center, has received the American Urological Association's 2007 Eugene Fuller Triennial Prostate Award, becoming only the 11th recipient in the award's 30-year history.

Released: 6-Jul-2007 9:00 AM EDT
Malaria-Resistant Mosquitoes Battle Disease with ‘Molecular Warhead’
UT Southwestern Medical Center

A team led by UT Southwestern Medical Center researchers has discovered why some mosquitoes are resistant to malaria, a finding that may one day help fight a disease that afflicts and kills millions of people.

Released: 5-Jul-2007 12:00 AM EDT
Specific Type of Cell Death May Accelerate Decompensated Heart Failure
UT Southwestern Medical Center

Autophagy, a normal process by which cells eat their own proteins to provide needed resources to the body in times of stress, may paradoxically cause harm to hearts already weakened by disease, researchers from UT Southwestern Medical Center have found.

25-Jun-2007 12:40 PM EDT
Substance in Tree Bark Could Lead to New Lung-cancer Treatment
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center have determined how a substance derived from the bark of the South American lapacho tree kills certain kinds of cancer cells, findings that also suggest a novel treatment for the most common type of lung cancer.

18-Jun-2007 1:00 PM EDT
Autism-Related Proteins Control Nerve Excitability
UT Southwestern Medical Center

Two proteins that are implicated in autism have been found to control the strength and balance of nerve-cell connections, researchers at UT Southwestern Medical Center have found.

4-Jun-2007 12:20 PM EDT
Hormone Helps Mice ‘Hibernate,’ Survive Starvation
UT Southwestern Medical Center

A key hormone enables starving mice to alter their metabolism and "hibernate" to conserve energy, revealing a novel molecular target for drugs to treat human obesity and metabolic disorders, UT Southwestern Medical Center researchers have found.

Released: 31-May-2007 12:00 AM EDT
First U.S. Morphea Registry and DNA Repository for both Adults and Children Established
UT Southwestern Medical Center

Dermatologists at UT Southwestern Medical Center are establishing a DNA repository aimed at people with morphea, a poorly understood, incurable and sometimes disfiguring disease that causes patches of skin to thicken and harden.

Released: 29-May-2007 12:00 PM EDT
Doctors, Engineers Develop New Wireless System to Detect Esophageal Reflux
UT Southwestern Medical Center

UT Southwestern Medical Center doctors and UT Arlington engineers have developed a wireless monitoring system that uses electrical impulses to track esophageal reflux.

24-May-2007 11:30 AM EDT
'Smart' Mice Teach Scientists About Learning Process, Brain Disorders
UT Southwestern Medical Center

Mice genetically engineered to lack a single enzyme in their brains are more adept at learning than their normal cousins, and are quicker to figure out that their environment has changed, a team led by researchers at UT Southwestern Medical Center has found.

Released: 17-May-2007 3:00 PM EDT
UT Southwestern Joins National Clinical Trial That Seeks to Uncover Long-term Effects of West Nile Virus
UT Southwestern Medical Center

UT Southwestern Medical Center has joined a national clinical trial to identify the long-term health effects of West Nile virus infection and to learn more about the disease's progression, symptoms and mortality.

Released: 17-May-2007 11:20 AM EDT
$50 MIllion Gift from T. Boone Pickens Foundation to Benefit UT Southwestern
UT Southwestern Medical Center

The T. Boone Pickens Foundation, named for the Texas icon and energy entrepreneur who founded it in 2006, has donated $50 million to ensure the continued excellence and prominence of UT Southwestern Medical Center into the future.

Released: 9-May-2007 11:00 AM EDT
Summer Sweat
UT Southwestern Medical Center

No need to sweat excessive perspiration. If you're sweating out embarrassing perspiration for an upcoming prom or summer wedding, consider botox injections.

Released: 9-May-2007 11:00 AM EDT
Make Seasonal Sun Block A Daily Habit
UT Southwestern Medical Center

Make seasonal sun block a daily habit. Popular outdoor activities from riding bikes to boating and beaches can mean wrinkles and skin cancer down the road if you don't take time to put on sun block, dermatologists at UT Southwestern warn.

Released: 9-May-2007 11:00 AM EDT
When Allergy Symptoms Bloom, Find the Right Medication
UT Southwestern Medical Center

Choosing the right medications is essential to gaining control over symptoms as allergy season comes into full bloom, allergy specialists at UT Southwestern Medical Center warn.

Released: 9-May-2007 11:00 AM EDT
Pregnant Women Can Keep Cool and Get Exercise with Simple Precautions
UT Southwestern Medical Center

Summer isn't the most fun time to be pregnant "“ heat and sweat add to the ordinary discomfort of pregnancy, and hormonal changes can make women less able to regulate body temperature. But it's still important for pregnant women to get healthful exercise, 30 minutes a day, three to four times a week, says Dr. Diane Hughes, an obstetrician/gynecologist at UT Southwestern Medical Center.

20-Apr-2007 4:20 PM EDT
Gene Analysis Might Explain Ethnic Differences in Sensitivity to Chemotherapy in Lung Cancer
UT Southwestern Medical Center

Analysis of three genetic mechanisms that cause non-small cell lung cancer might explain why East Asians respond better than other ethnic groups to a certain type of chemotherapy, a team led by UT Southwestern Medical Center researchers has found.

20-Apr-2007 4:35 PM EDT
A Relative of Anti-aging Gene Klotho Also Influences Metabolic Activity, Obesity
UT Southwestern Medical Center

A relative of the anti-aging gene Klotho helps activate a hormone that can lower blood glucose levels in fat cells of mice, making it a novel target for developing drugs to treat human obesity and diabetes, UT Southwestern Medical Center researchers have found.

6-Apr-2007 4:40 PM EDT
Massive Gene Screening Points Way to More Effective Chemotherapy
UT Southwestern Medical Center

Using a technology that can quickly screen all 20,000-plus human genes for biological activity, scientists have isolated 87 genes that seem to affect how sensitive human cancer cells are to certain chemotherapy drugs.

Released: 4-Apr-2007 12:30 PM EDT
UT Metroplex Institutions to Collaborate on Biomedical Research
UT Southwestern Medical Center

Researchers from the three University of Texas campuses in the Dallas-Fort Worth metropolitan area are combining their expertise in biomedical science, engineering and physical sciences on projects aimed at solving real-world medical problems.

30-Mar-2007 1:00 PM EDT
Amphetamine, Cocaine Use Increase Risk of Stroke in Young Adults
UT Southwestern Medical Center

Increasing rates of amphetamine and cocaine use by young adults significantly boost their risk of stroke, with amphetamine abuse associated with the greatest risk, researchers at UT Southwestern Medical Center report.

Released: 26-Mar-2007 12:00 AM EDT
Magnetic System Could be Key to Surgery without Scars
UT Southwestern Medical Center

Physicians at UT Southwestern Medical Center and engineers at UT Arlington have collaborated to invent a groundbreaking system that could be key to delivering on the promise of surgery without scars.

19-Mar-2007 3:00 PM EDT
Cells Use ‘Noise’ to Make Cell-fate Decisions
UT Southwestern Medical Center

Electrical noise, like the crackle heard on AM radio when lightning strikes nearby, is a nuisance that wreaks havoc on electronic devices. But within cells, a similar kind of biochemical "noise" is beneficial, helping cells transform from one state to another, according to a new study led by a UT Southwestern Medical Center researcher.

20-Mar-2007 5:55 PM EDT
Tiny Molecule Controls Stress-induced Heart Disease
UT Southwestern Medical Center

A tiny snippet of RNA, a chemical cousin of DNA, controls damage to the heart under several types of stress, researchers at UT Southwestern Medical Center have found.

Released: 20-Mar-2007 12:00 AM EDT
UT Southwestern Leaders to Receive National Award for Medical Research Accomplishments
UT Southwestern Medical Center

Two Nobel laureates from UT Southwestern Medical Center and their mentor, a distinguished chair of internal medicine at this institution, will receive Research!America's inaugural Builders of Science Award for their achievements in developing UT Southwestern into one of the world's premier research institutions.

16-Mar-2007 4:05 PM EDT
Gene Controlling Circadian Rhythms May be Involved in Onset of Bipolar Disorder
UT Southwestern Medical Center

Disrupt the gene that regulates the biological clocks in mice and they become manic, exhibiting behaviors similar to humans with bipolar disorder, UT Southwestern Medical Center researchers have found.

Released: 16-Mar-2007 4:00 PM EDT
Plagued by Diet Disasters? a Visit to a Registered Dietician Could Help
UT Southwestern Medical Center

Americans are no strangers to dieting failure. Studies indicate more than one-third of adults are trying to lose weight, but few have long-term success. Many can't stick to diets and exercise routines and struggle to stay afloat in a sea of popular diets, fitness programs and foods with "healthy" claims.

Released: 13-Mar-2007 12:00 AM EDT
Infection Detectives Use Disease ‘Fingerprints’ to Track Common Infections in Children
UT Southwestern Medical Center

Infectious disease specialists at UT Southwestern Medical Center have found a new method for identifying suspect viruses and bacteria that cause some of the most common acute infections in children.

5-Mar-2007 4:15 PM EST
Cannibalistic Signals Help Mammalian Embryos Develop Normally
UT Southwestern Medical Center

A cannibalistic process called autophagy spurs dying embryonic stem cells to send "eat me" and "come get me" signals to have their corpses purged, a last gasp that paves the way for normal mammalian development, UT Southwestern Medical Center researchers have found.

Released: 27-Feb-2007 12:00 AM EST
Innovative Treatment for Migraines Combines Botox and Surgery
UT Southwestern Medical Center

Five years ago, Sharon Schafer Bennett suffered from migraines so severe that the headaches disrupted her life, kept her from seeking a job and interfered with participation in her children's daily activities.

Released: 19-Feb-2007 9:00 AM EST
CRP Liver Protein Induces Hypertension, Researchers Have Found
UT Southwestern Medical Center

C-Reactive Protein, widely regarded as a key player in risk factor for hypertension and other forms of cardiovascular disease, may also plays a direct role in the onset of hypertension, researchers at UT Southwestern Medical Center have found.

13-Feb-2007 3:10 PM EST
Studies of Population Genetics, Evolution Are an Exercise in Bad Taste
UT Southwestern Medical Center

Scientific studies of why foods such as Brussels sprouts and stout beer are horribly bitter-tasting to some people but palatable to others are shedding light on a number of questions, from the mechanisms of natural selection to understanding how our genes affect our dietary habits.

2-Feb-2007 8:00 PM EST
Sea Creature's Toxin Could Lead to Promising Cancer Treatment
UT Southwestern Medical Center

A toxin derived from a reclusive sea creature resembling a translucent doughnut has inspired UT Southwestern Medical Center researchers to develop a related compound that shows promise as a cancer treatment.

1-Feb-2007 3:20 PM EST
Supplemental Therapy Can Ease Pain for People Suffering from Common Jaw Disorder
UT Southwestern Medical Center

A new supplemental therapy that teaches pain coping and biofeedback skills can reduce pain, the potential for chronic pain and health-care costs for millions of Americans suffering from a common jaw disorder, UT Southwestern Medical Center researchers have found.

Released: 1-Feb-2007 2:40 PM EST
New Biomarker Test Could Predict Outcome for Bladder Cancer Patients
UT Southwestern Medical Center

A set of molecular biomarkers might better predict the recurrence of bladder cancer than conventional prognostic features such as the stage or grade of the malignancy at the time it is discovered, UT Southwestern Medical Center researchers have found.

Released: 31-Jan-2007 12:00 AM EST
Different Treatment May be Needed for Infection-Related Breathing Problems
UT Southwestern Medical Center

New research suggests that different treatments may be needed for chronic asthma, depending on whether it results from allergies or lung infections.

Released: 29-Jan-2007 3:45 PM EST
Risk for Stroke, Death Not Higher for Sickle Cell Children with Early Complications
UT Southwestern Medical Center

Children with sickle cell disease who experienced major complications such as pain and lung disease early in life are at no greater risk for stroke or death during later childhood, new research from UT Southwestern Medical Center shows.

24-Jan-2007 3:10 PM EST
Novel Laboratory Technique Nudges Genes Into Activity
UT Southwestern Medical Center

A new technique that employs RNA, a tiny chemical cousin of DNA, to turn on genes could lead to therapeutics for conditions in which nudging a gene awake would help alleviate disease, researchers at UT Southwestern Medical Center say.

Released: 16-Jan-2007 12:00 AM EST
Napoleon’s Mysterious Death Unmasked
UT Southwestern Medical Center

A new investigation into Napoleon Bonaparte's cause of death might finally put to rest nearly 200 years of lingering mysteries about the illness that killed the French emperor during his island exile, a UT Southwestern Medical Center scientist reports.

Released: 8-Jan-2007 11:15 AM EST
Tracing Agent, Microbubbles, Ultrasound Combo Helps Test Cancer Therapy’s Effectiveness
UT Southwestern Medical Center

An inexpensive tracing agent used in combination with ultrasound can pinpoint how effectively drugs targeting pancreatic cancer work, researchers at UT Southwestern Medical Center have demonstrated for the first time.

20-Dec-2006 6:10 PM EST
Molecular ‘On/Off Switch’ Controls Immune Defenses Against Viruses
UT Southwestern Medical Center

Much like flipping a light switch, the hepatitis C virus turns on human immune defenses upon entering the body but also turns off those defenses by manipulating interaction of key cellular proteins, UT Southwestern Medical Center researchers have found.

22-Dec-2006 11:00 AM EST
Profiling of Cancer Genes May Lead to Better and Earlier Detection of Solid Human Cancers
UT Southwestern Medical Center

A research team at UT Southwestern Medical Center has for the first time identified several genes whose expression is lost in four of the most common solid human cancers "“ lung, breast, prostate and colon cancer.

13-Dec-2006 3:25 PM EST
Drug That Chokes Off Tumor Blood Vessels Offers New Hope to Lung Cancer Patients
UT Southwestern Medical Center

Patients suffering from the most common type of lung cancer experienced a 20-percent improvement in overall survival in a national clinical trial of a drug that chokes off the blood vessels nourishing tumors, a multicenter study has found.

Released: 13-Dec-2006 12:00 AM EST
Antibiotic Ear Drops Favored Over Popular Oral Antibiotics for Ear Infections
UT Southwestern Medical Center

A multicenter study on treating common ear infections in children with ear tubes adds to a growing body of evidence that favors antibiotic ear drops over antibiotics swallowed in pill or liquid form in such cases, a UT Southwestern Medical Center researcher reports.

Released: 12-Dec-2006 12:00 AM EST
Even Slight Holiday Weight Gain Can Set Stage for Obesity, Health Risks
UT Southwestern Medical Center

Although some Americans gain five to seven pounds with a diet of big meals and sweets between Thanksgiving and New Year's Day, most people only gain a pound or two during the holidays, according to a UT Southwestern Medical Center registered dietitian.

Released: 11-Dec-2006 3:40 PM EST
UT Southwestern Ranked Among America’s Top Biomedical Research Universities
UT Southwestern Medical Center

UT Southwestern Medical Center ranked among the top 10 American institutions in three of the six biomedical fields assessed in an independent analysis of scientific research impact.



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