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Released: 11-Oct-2002 12:00 AM EDT
Drug Therapy Eases Chronic Depression
UT Southwestern Medical Center

A team of scientists representing 12 collaborating health-care centers, including UT Southwestern Medical Center at Dallas, have found that antidepressant therapy -- specifically sertaline hydrochloride, or Zoloft -- can enhance the lives of many chronically depressed patients.

Released: 10-Oct-2002 12:00 AM EDT
UT Southwestern Named One of 10 NIH Centers for 'Human Proteome Project'
UT Southwestern Medical Center

UT Southwestern Medical Center at Dallas is one of 10 U.S. institutions to be awarded a multimillion-dollar National Institutes of Health grant to develop faster methods to study proteins that are critical to drug development.

Released: 2-Oct-2002 12:00 AM EDT
Cannon Named UT Southwestern Neurology Chairman
UT Southwestern Medical Center

Dr. Stephen Cannon, a neurologist at Massachusetts General Hospital and neurobiologist at Harvard Medical School, has been named chairman of neurology at UT Southwestern Medical Center at Dallas.

Released: 28-Sep-2002 12:00 AM EDT
Computers, Television Before Bedtime Can Sabotage Kids' School Work
UT Southwestern Medical Center

Parents who want their children to get plenty of sleep, grow up healthy and do well in school often harbor sleep saboteurs under their roofs -- sometimes in the children's own bedrooms, according to a sleep expert at UT Southwestern Medical Center at Dallas.

Released: 24-Sep-2002 12:00 AM EDT
Clue to Understanding Tolerance to Drugs of Abuse
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas and their colleagues have uncovered new information that will help brain researchers better understand a person's tolerance to drugs of abuse and open new avenues of investigation into the relationship of addictive-drug usage and the biological causes of mood disorders.

Released: 20-Sep-2002 12:00 AM EDT
Protein That Both Instigates, Inhibits Heart Growth in Mice
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have discovered a protein that regulates growth and development of the heart from its fetal stage to adulthood.

Released: 20-Sep-2002 12:00 AM EDT
$2 Million Grant to Purchase 30-Ton Superconducting Magnet
UT Southwestern Medical Center

The National Institutes of Health has awarded a $2 million grant to UT Southwestern Medical Center at Dallas for the purchase of a 30-ton, 800 MHz nuclear magnetic resonance (NMR) spectrometer that will add strength to the Department of Biochemistry's research programs.

Released: 19-Sep-2002 12:00 AM EDT
Texas Rural Health Association Renames Award for Late Dr. Marion Zetzman
UT Southwestern Medical Center

The Texas Rural Health Association's Person Who Made a Difference Award has been re-christened in honor of former UT Southwestern Medical Center at Dallas faculty member Dr. Marion Zetzman.

Released: 17-Sep-2002 12:00 AM EDT
NIH Grant to Establish First Sickle Cell Center in Southwest
UT Southwestern Medical Center

A multi-million-dollar five-year federal grant will enable The University of Texas Southwestern Medical Center at Dallas and The University of Texas at Dallas to establish the first National Institutes of Health sickle cell center in the Southwest.

Released: 14-Sep-2002 12:00 AM EDT
UT Southwestern Scientist Making Antarctica Research Interactive
UT Southwestern Medical Center

Dr. Shane Kanatous, who is leaving for a research expedition to Antarctica in late September, plans to take some Dallas schoolchildren along with him - via the World Wide Web.

Released: 11-Sep-2002 12:00 AM EDT
Causes, Treatment of Bipolar Disease Coupled with Drug Abuse Studied
UT Southwestern Medical Center

The lasting effects of Sept. 11 on everyday citizens caused Dr. Vicki Nejtek, assistant professor of psychiatry at UT Southwestern Medical Center at Dallas, to wonder how terrorism's aftermath impacts her vulnerable research population -- patients suffering from dual diagnosis.

Released: 5-Sep-2002 12:00 AM EDT
High-Tech CD Helps Save Children's Lives in Emergencies
UT Southwestern Medical Center

Playing a new interactive CD-ROM may help save the lives of children with real-life emergencies that annually send millions to hospital emergency rooms.

Released: 5-Sep-2002 12:00 AM EDT
Effective, Safe Vaccine Against Deadly Bioterrorism Toxin Ricin
UT Southwestern Medical Center

UT Southwestern Medical Center at Dallas researchers have developed a vaccine in mice against the deadly toxin ricin. Ricin has been used as a biological weapon in many parts of the world.

Released: 4-Sep-2002 12:00 AM EDT
Key Protein That Establishes Communication within Central Nervous System Identified
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have identified one of the key proteins involved in the establishment of the central nervous system.

Released: 29-Aug-2002 12:00 AM EDT
Caffeine-Signaling Activity in Brain Function
UT Southwestern Medical Center

Every morning millions of Americans reach for the world's most popular drug to help them start their day.

Released: 29-Aug-2002 12:00 AM EDT
NIH-Funded Incontinence Study First of Its Kind
UT Southwestern Medical Center

A new clinical trial at UT Southwestern Medical Center at Dallas seeks to answer a question incontinence specialists have long struggled with -- which of two common, established surgeries for female urinary stress incontinence is better?

Released: 27-Aug-2002 12:00 AM EDT
UT Southwestern Research Prolongs Lives of Children with Cancer
UT Southwestern Medical Center

Two months shy of his 6th birthday, Sam Helsley of Fort Worth savors stepping up to bat. Playing T-ball may be a rite of passage for most boys his age, but for Sam, who's had more than his share of opponents, it's a hard-won victory. When he was 23 months old, he was diagnosed with an advanced-stage childhood cancer.

Released: 23-Aug-2002 12:00 AM EDT
Nationwide Tissue Distribution Plan Devised
UT Southwestern Medical Center

As a result of the need for tissue donations for victims of the Sept. 11 terrorist attacks, a nationwide plan has been developed to make tissue available in the event of future disasters.

23-Aug-2002 12:00 AM EDT
Gene Could Hold Key to Predicting, Combating Abnormal Heart Growth
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have identified a gene they believe could predict risk for developing enlarged hearts and lead to treatments to control life-threatening heart growth.

Released: 22-Aug-2002 12:00 AM EDT
UT Southwestern Researchers Decode Filament Structures
UT Southwestern Medical Center

Scientists at UT Southwestern Medical Center at Dallas have found the blueprint for how filaments assemble during the development of caveolae, a membrane system that organizes signaling molecules used by cells to communicate with each other.

Released: 15-Aug-2002 12:00 AM EDT
Protein Transforms Sedentary Muscles into Exercised Muscles
UT Southwestern Medical Center

Researchers have discovered a second protein found in skeletal muscle that can transform sedentary muscles into energy-producing, exercised muscles.

Released: 13-Aug-2002 12:00 AM EDT
Immunotherapy Shots Take the Sting Out of Fire Ant Bites
UT Southwestern Medical Center

Kenn Mingus knew something was dreadfully wrong 10 minutes after fire ants bit him. His lips became numb; his breathing was labored, he felt dizzy, and then passed out. He was rushed to the emergency room.

Released: 2-Aug-2002 12:00 AM EDT
Low-Carbohydrate, High-Protein Diets Increase Risk of Kidney Stones and May Raise Bone Loss Risk
UT Southwestern Medical Center

Popular low-carbohydrate, high-protein diets may result in rapid weight loss, but researchers at UT Southwestern Medical Center at Dallas report that they also pose serious health problems, including an increase in the risk of kidney stones and a possible higher risk of bone loss.

1-Aug-2002 12:00 AM EDT
New Insight Into How Eyes Become Wired to the Brain
UT Southwestern Medical Center

A crucial piece of the puzzle into how the eye becomes wired to the brain has been revealed by scientists at the Salk Institute for Biological Studies in La Jolla, Calif., and UT Southwestern Medical Center at Dallas.

Released: 24-Jul-2002 12:00 AM EDT
Antiretroviral Therapy in HIV-Infected Children Can Stop Neurological Damage
UT Southwestern Medical Center

Treating HIV-infected children with antiretroviral therapy can stop and potentially even reverse neurological damage caused by HIV, doctors from UT Southwestern Medical Center at Dallas report in an international study.

22-Jul-2002 12:00 AM EDT
Extended-Release Niacin Proven Effective in Low Doses for Diabetics
UT Southwestern Medical Center

Niacin, a medication once discouraged for the treatment of lipid abnormalities in patients with diabetes, has the potential ability, when given in low doses, to be well-tolerated and effective, according to UT Southwestern Medical Center at Dallas researchers, who led the multicenter trial.

Released: 20-Jul-2002 12:00 AM EDT
Structural Mechanism of Cell Enzyme Revealed
UT Southwestern Medical Center

UT Southwestern Medical Center at Dallas researchers, using X-ray crystallography, have discovered how a particular cell enzyme finds its target and clearly carries out its role in the complicated process of cellular communication.

Released: 19-Jul-2002 12:00 AM EDT
ACE Inhibitor Drug Used to Delay Heart Failure as Effective in Blacks as Whites
UT Southwestern Medical Center

A drug widely used to treat patients with heart failure is as effective for black patients as it is for white patients, according to researchers at UT Southwestern Medical Center at Dallas.

5-Jul-2002 12:00 AM EDT
Key Photoreceptor in Fungi Identified after 40-Year Search
UT Southwestern Medical Center

After 40 years of searching for the photoreceptor that controls multiple vital processes in fungi, researchers at UT Southwestern Medical Center at Dallas have discovered the protein that triggers this phenomenon.

Released: 8-Jun-2002 12:00 AM EDT
Trojan Horse Technology Destroys Blood Supply to Cancer Tumors in Mice
UT Southwestern Medical Center

Researchers at The University of Texas M. D. Anderson Cancer Center in Houston and The University of Texas Southwestern Medical Center at Dallas have demonstrated in mice that a new drug formed by linking a vascular endothelial growth factor to a toxin will target and destroy the blood vessels supplying a malignant tumor.

6-Jun-2002 12:00 AM EDT
Better Tests to Detect Congenital Syphilis in Newborns
UT Southwestern Medical Center

A UT Southwestern Medical Center at Dallas research team has developed two blood tests that quickly and reliably diagnose congenital syphilis in newborns.

Released: 5-Jun-2002 12:00 AM EDT
Genetic Testing, Computer Risk-Assessment Software Effective in Predicting Breast Cancer
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have shown that examining breast cells' molecular makeup can provide a better way to predict breast-cancer risk and that computer-based risk-assessment tools can help identify women who would benefit from genetic testing.

4-Jun-2002 12:00 AM EDT
Cocaine Abuse in Warm Environments Impairs Body's Perception of Heat, can be Lethal
UT Southwestern Medical Center

Cocaine, even in small amounts, can be fatal when taken in warm environments, such as hot weather, crowded nightclubs or rave parties -- all-night dance parties where illicit cocaine use is common -- according to researchers at UT Southwestern Medical Center at Dallas.

Released: 31-May-2002 12:00 AM EDT
HDTV System Allows Complex Neurological Surgery to be Viewed by Entire Operating Room
UT Southwestern Medical Center

A state-of-the-art television screen is changing the way UT Southwestern neurosurgeons and their colleagues look at surgery.

Released: 23-May-2002 12:00 AM EDT
Use Caution, Ask Questions Before Attending Botox Party
UT Southwestern Medical Center

A new rage -- the Botox party -- may seem innocent and even fun for a group who wants to participate in this nonsurgical cosmetic procedure. But the chairman of plastic surgery at UT Southwestern Medical Center at Dallas cautions that there can be unwanted consequences.

Released: 22-May-2002 12:00 AM EDT
High-Tech Treatment for Babies Who Would Otherwise Die from Brain Tumors
UT Southwestern Medical Center

When 10-month-old O'Neal Scrivner stopped using her left arm, her parents worried she might have injured it. They never guessed their firstborn's brain was being ravaged by a rare, almost-always fatal, cancerous tumor.

17-May-2002 12:00 AM EDT
Biochemical Connection Between High-Fat Diets and Increased Colon-Cancer Risk
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have uncovered what could be a key clue in tracing the connection between high-fat diets and increased colon-cancer risk.

Released: 15-May-2002 12:00 AM EDT
Disparities in Black Americans' Responses to Heart-Failure Therapies May Signal Different Disease
UT Southwestern Medical Center

An emerging database of genetic variations in black Americans may explain the differences in their response to traditional heart-failure therapies, according to a researcher at UT Southwestern Medical Center at Dallas.

Released: 7-May-2002 12:00 AM EDT
Spring May Bring West Nile Virus to Texas
UT Southwestern Medical Center

With spring rain and warm weather come mosquitoes. This year, local public health officials are worried the mosquitoes will bring something new with them -- West Nile virus. It could make its first appearance in Texas this summer, according to the assistant professor of internal medicine at UT Southwestern Medical Center at Dallas.

3-May-2002 12:00 AM EDT
Cell, Genetic Environment Behind Nerve-Tissue Tumors that Lead to Cancer Identified
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas believe they are hot on the trail of a way to prevent benign tumors that attack the nervous system and can be precursors to terminal cancer.

3-May-2002 12:00 AM EDT
Natural Compound Used in India Reduces Cholesterol
UT Southwestern Medical Center

UT Southwestern Medical Center at Dallas researchers have helped prove that a naturally occurring compound used for centuries as a dietary supplement in India can help lower cholesterol levels.

Released: 2-May-2002 12:00 AM EDT
Drug Breaks for HIV-Infected Individuals May Put Certain Immune Cells at Risk
UT Southwestern Medical Center

Disruption of antiretroviral therapy by patients infected with HIV may be putting certain T-cells in their bloodstream at greater risk for infection with the deadly virus if it is allowed to rebound.

Released: 1-May-2002 12:00 AM EDT
Gene Responsible for a Rare Body-Fat Disorder Identified
UT Southwestern Medical Center

An international team of researchers led by scientists at UT Southwestern Medical Center at Dallas have identified the gene that causes a rare body-fat disorder, a discovery that may ultimately expand the understanding of obesity-related illnesses.

1-May-2002 12:00 AM EDT
Lung-Cancer Tumor Suppressor Genes Identified
UT Southwestern Medical Center

Researchers at The University of Texas M. D. Anderson Cancer Center and The University of Texas Southwestern Medical Center at Dallas have identified three lung-cancer tumor suppressor genes on chromosome 3 that dramatically reduced human lung cancer growth in mice and for which gene therapy trials with humans will begin within a year.

Released: 25-Apr-2002 12:00 AM EDT
Gerontologist Offers Ways to Find the Right Nursing Home
UT Southwestern Medical Center

A recent study found that nine out of 10 U.S. nursing homes lack adequate staffing to properly care for patients. But a gerontology specialist at UT Southwestern Medical Center at Dallas said consumers who conduct research on prospective facilities and discuss all options with family members can find an appropriate nursing home for themselves or loved ones.

Released: 23-Apr-2002 12:00 AM EDT
Researcher Receives $15 Million Grant from Japan Science and Technology Corp.
UT Southwestern Medical Center

UT Southwestern Medical Center at Dallas researcher Dr. Masashi Yanagisawa has received a five-year, $15M grant from Japan Science and Technology Corp. to expand his research on receptor genes and the roles they play in the body.

19-Apr-2002 12:00 AM EDT
Certain Proteins Play Unexpected Roles in Genetic Transcription
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have proved that a group of proteins previously thought to have no role in turning genes on and off actually plays a part in that process, which is critical to both human development and understanding some diseases.

Released: 12-Apr-2002 12:00 AM EDT
Researchers Link Gene with Kidney Stones, Bone Loss in Patients Who Absorb Too Much Calcium
UT Southwestern Medical Center

A team of researchers at UT Southwestern Medical Center has identified a set of genetic abnormalities that increase risk for kidney stones and could indicate increased risk for osteoporosis.

12-Apr-2002 12:00 AM EDT
Protein Transforms Sedentary Muscles to Resemble Exercised Muscles
UT Southwestern Medical Center

A calcium-signaling protein transforms sedentary, easily fatigued muscles into energy-producing, fatigue-resistant muscles, UT Southwestern Medical Center at Dallas researchers report.

1-Apr-2002 12:00 AM EST
Gene that Controls Formation of Heart Chambers Identified
UT Southwestern Medical Center

Scientists at UT Southwestern Medical Center at Dallas and their colleagues at UT Austin have identified a gene that controls formation of the heart's ventricles -- a finding that may eventually lead to preventing some of the most lethal heart defects in American children.



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