Latest News from: JAMA - Journal of the American Medical Association

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23-Mar-2006 4:00 PM EST
Disclosure of Physicians’ Compensation May Increase Patients’ Loyalty
JAMA - Journal of the American Medical Association

Providing notices that explain how physicians are paid appears to increase patients' knowledge about compensation models, does not harm trust and may increase the loyalty patients feel toward their physicians.

23-Mar-2006 4:00 PM EST
Cardiac Exam Skills Appear Similar Among Med Students, Resident Physicians
JAMA - Journal of the American Medical Association

Based on findings from a computer-based, multimedia, interactive test, cardiac examination skills do not appear to differ among third-year medical students, resident physicians, faculty members or private practitioners, but may decline after years in practice.

16-Mar-2006 4:00 PM EST
Genetic Testing Doesn't Detect All Cancer-Associated Mutations
JAMA - Journal of the American Medical Association

Despite a negative (normal) genetic test for mutations in the BRCA1 and BRCA2 genes, about 12 percent of breast cancer patients from high-risk families carried previously undetected cancer-associated mutations, according to a study in the March 22/29 issue of JAMA, a theme issue on women's health.

16-Mar-2006 4:00 PM EST
Treatment of Mother’s Depression Reduces Risk of Disorders in Children
JAMA - Journal of the American Medical Association

Remission of a mother's depression within the first three months of treatment decreases the likelihood of her children having psychiatric disorders, such as mood or disruptive behavior disorders, within the same time period. Mothers who remain depressed increase the risk of her children having these disorders, according to a study in the March 22/29 issue of JAMA, a theme issue on women's health.

16-Mar-2006 4:00 PM EST
Exercise Unlikely to Cause Sudden Cardiac Death in Women
JAMA - Journal of the American Medical Association

Sudden cardiac death during exertion is an extremely rare occurrence in women, and regular moderate to vigorous exercise may significantly lower the long-term risk, according to a study in the March 22/29 issue of JAMA, a theme issue on women's health.

16-Mar-2006 4:00 PM EST
X Chromosomes Key to Sex Differences in Health
JAMA - Journal of the American Medical Association

Females have two X chromosomes and males only have one"”and this simple fact, along with the occurrence of what geneticists call mosaicism, may not only explain why women are less susceptible than men to certain genetic diseases, but also may account for the female prevalence in the incidence of other conditions and even sex differences in behavior, according to a special communication in the March 22/29 issue of JAMA, a theme issue on women's health.

9-Mar-2006 4:00 PM EST
Humidity Does Not Improve Symptoms for Children Treated with Croup
JAMA - Journal of the American Medical Association

For children with moderate to severe croup treated in the emergency department, use of high humidity did not improve symptoms more than low humidity or mist therapy, according to an article in the March 15 issue of JAMA.

9-Mar-2006 4:00 PM EST
Anti-Thrombotic Medication Reduces Risk of Death for Heart Attack Patients
JAMA - Journal of the American Medical Association

Heart attack patients who have a certain pattern on an electrocardiogram significantly reduced their risk of death and having another heart attack at 30 days with the medication fondaparinux, without an increased risk of bleeding and strokes.

10-Mar-2006 2:20 PM EST
Blood Pressure Meds Linked to Reduced Risk of Alzheimer’s Disease
JAMA - Journal of the American Medical Association

Taking medications to lower blood pressure, particularly those known as diuretics, may be associated with a lower incidence of Alzheimer's disease.

10-Mar-2006 2:25 PM EST
Cognitive Impairment Appears to Be Common in ALS Patients
JAMA - Journal of the American Medical Association

In a study of 40 patients with amyotrophic lateral sclerosis (ALS), about one-third showed evidence of cognitive impairment, but these deficits did not appear to be related to survival, according to a study in the March issue of Archives of Neurology, one of the JAMA/Archives journals.

10-Mar-2006 4:00 PM EST
Telephone Counseling and Care May Help Smokers Quit
JAMA - Journal of the American Medical Association

Smokers who receive telephone care and counseling for smoking cessation have higher rates of stopping smoking than those who receive routine care by health care providers.

10-Mar-2006 2:35 PM EST
Faxed Physician Alerts May Not Improve Patient Antidepressant Adherence
JAMA - Journal of the American Medical Association

Faxing pharmacy information to alert physicians when their patients fail to refill their prescriptions for antidepressants may not increase the rates of patients taking their drugs as prescribed.

9-Mar-2006 4:00 PM EST
High-intensity Statin Therapy Could Induce Regression of Coronary Atherosclerosis
JAMA - Journal of the American Medical Association

Patients treated with very intensive statin therapy lowered LDL-C levels on average by about 50 percent, increased HDL-C levels by 15 percent, and showed regression of coronary atherosclerosis.

9-Mar-2006 4:00 PM EST
Medication Reduces Risk of Adverse Events for Patients with Acute Coronary Syndromes
JAMA - Journal of the American Medical Association

Patients with acute coronary syndromes who were pre-treated with the anti-platelet agent clopidogrel before undergoing a procedure such as balloon angioplasty or stent placement had a reduced risk of adverse events if they received the anti-clotting drug abciximab.

9-Mar-2006 4:00 PM EST
Paclitaxel-Releasing Stent More Effective than Intra-Coronary Radiation Therapy
JAMA - Journal of the American Medical Association

Insertion of stents that release the drug paclitaxel to treat stenosis within an implanted bare-metal stent in a coronary artery reduces the risk of subsequent re-narrowing within the stent, when compared with treatment using intra-coronary radiation.

9-Mar-2006 4:00 PM EST
Sirolimus-Releasing Stents More Effective than VBT for Treating Restenosis
JAMA - Journal of the American Medical Association

David R. Holmes, Jr., M.D., and colleagues with the SISR trial compared the use of vascular brachytherapy (VBT "“ intra-coronary radiation therapy) with implantation of the sirolimus-eluting stent for the treatment of restenosis occurring within a previously placed bare-metal stent.

2-Mar-2006 5:25 PM EST
Fine Particle Air Pollution Associated With Respiratory and Cardiovascular Diseases
JAMA - Journal of the American Medical Association

Being exposed to fine particle matter air pollution increases a person's risk for hospital admission for cardiovascular and respiratory diseases, according to a study in the March 8 issue of JAMA.

2-Mar-2006 5:25 PM EST
Coffee Consumption Linked to Heart Attack for Persons With Gene Variation
JAMA - Journal of the American Medical Association

Individuals who have a genetic variation associated with slower caffeine metabolism appear to have an increased risk of non-fatal heart attack associated with higher amounts of coffee intake, according to a study.

2-Mar-2006 5:30 PM EST
Antibiotic Distribution Not Sufficient For Eye Infection in Ethiopian Communities
JAMA - Journal of the American Medical Association

Treating trachoma, an eye infection that can lead to blindness, with a single mass antibiotic distribution in Ethiopian communities with high prevalence of infection is not effective in eliminating the disease.

2-Mar-2006 9:45 PM EST
Antidepressants and Risk of Suicidal Thoughts, Behaviors in Children
JAMA - Journal of the American Medical Association

An analysis of data from 24 clinical trials suggests that antidepressant medications may be linked to a modest increase in the risk of suicidal thoughts and behaviors in children, according to an article.

2-Mar-2006 9:50 PM EST
Genetic Factors, Neuroticism and with Future Development of Anorexia
JAMA - Journal of the American Medical Association

In a large study of Swedish twins, anorexia nervosa appears to be moderately heritable and linked to neurotic behavior early in life among women, according to an article.

23-Feb-2006 4:00 PM EST
Stem Cell Mobilization Therapy Ineffective in Repairing Heart Attack Damage
JAMA - Journal of the American Medical Association

Therapy that involved bone marrow stem cells did not improve cardiac function in patients following a heart attack, according to a study.

23-Feb-2006 4:00 PM EST
Combat Duty in Iraq Linked With High Use of Mental Health Services
JAMA - Journal of the American Medical Association

About one-third of U.S. military personnel from the war in Iraq access mental health services after their return home, according to a study.

23-Feb-2006 4:00 PM EST
Atomic Bomb Survivors and Incidence of Thyroid Diseases
JAMA - Journal of the American Medical Association

Survivors of the two atomic bombs in Japan 60 years ago who had a higher exposure to radiation now have a greater incidence of certain thyroid diseases, including tumors and cysts, and that risk increases with being younger at the time of exposure.

23-Feb-2006 4:00 PM EST
Overactive Thyroid Associated With Development of Abnormal Heart Rhythm
JAMA - Journal of the American Medical Association

Having an overactive thyroid gland is linked with an increased risk for atrial fibrillation (a type of abnormal heart rhythm), but neither an over- or under active thyroid gland is associated with a higher risk for other cardiovascular problems or increased risk of death.

23-Feb-2006 6:45 PM EST
Why Women Have Higher Risk of Death After Coronary Artery Bypass Surgery
JAMA - Journal of the American Medical Association

Higher rates of infection among women undergoing coronary artery bypass surgery may explain why women have higher risk of death than men following the procedure, according to a study.

23-Feb-2006 6:45 PM EST
Higher Optimism Levels Associated with Lower Risk of Cardiovascular Death
JAMA - Journal of the American Medical Association

The most optimistic elderly men in a Dutch study had a lower risk of cardiovascular death over 15 years when compared with the least optimistic, according to an article.

23-Feb-2006 6:50 PM EST
Cocoa Intake Linked to Lower Blood Pressure, Reduced Risk of Death
JAMA - Journal of the American Medical Association

A study of elderly Dutch men indicates that eating or drinking cocoa is associated with lower blood pressure and a reduced risk of death, according to an article.

16-Feb-2006 4:00 PM EST
Comparison of Drug-Releasing Coronary Stents Show Similar Effectiveness
JAMA - Journal of the American Medical Association

Use of coronary stents that release the drugs sirolimus or paclitaxel produced similar results in patients with new coronary artery lesions, according to a study.

16-Feb-2006 4:00 PM EST
Most Hospitals Do Not Initially Require Board Certification of Pediatricians
JAMA - Journal of the American Medical Association

A survey of 200 hospitals found that nearly 80 percent do not require board certification of pediatricians at the time of initial granting of hospital privileges, although most hospitals do require board certification at some point in the pediatrician's tenure, according to a study.

16-Feb-2006 4:00 PM EST
Helmet Use Associated with Reduced Risk of Head Injury for Skiers, Snowboarders
JAMA - Journal of the American Medical Association

Alpine skiers and snowboarders who wear a helmet have a reduced risk of head injury, according to a study.

9-Feb-2006 4:00 PM EST
Medication Shows Modest Benefit in Reducing Weight, Improving HDL Levels
JAMA - Journal of the American Medical Association

Use of the weight-loss medication rimonabant produced modest yet sustained weight loss after 2 years, and improved HDL cholesterol and triglyceride levels, according to a study.

9-Feb-2006 4:00 PM EST
Abnormal Findings on Exercise Stress Testing and Lower Socioeconomic Status
JAMA - Journal of the American Medical Association

Individuals who have abnormal findings on exercise stress testing are more likely to have lower than higher socioeconomic status, and these physiologic characteristics may help account for the correlation between low SES and a higher rate of death, according to a study.

9-Feb-2006 4:00 PM EST
Morphine, Topical Anesthesia Found Effective in Treating Pain in Newborn Infants
JAMA - Journal of the American Medical Association

Intravenous morphine used alone or with topical tetracaine effectively reduced levels of pain in preterm newborn infants undergoing central line insertion procedures, according to a study.

10-Feb-2006 1:10 PM EST
Violations of Prescription Drugs’ Black Box Warnings in Outpatient Settings
JAMA - Journal of the American Medical Association

Less than 1 percent of outpatients who received medication in 2002 were prescribed a medication that violated a prescription drug's black box warning, according to a study in the February 13 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

10-Feb-2006 1:05 PM EST
Low-Carbohydrate Diets Appear Effective, But May Raise Cholesterol Levels
JAMA - Journal of the American Medical Association

A synthesis of data from five previous clinical trials suggests that both low-fat and low-carbohydrate diets appear to be effective for weight loss up to one year, but low-carbohydrate diets may be linked to higher overall and LDL or "bad" cholesterol levels, according to a study.

10-Feb-2006 1:10 PM EST
Tumor Size Related to Lung Cancer Spread
JAMA - Journal of the American Medical Association

Smaller tumors in the lungs appear to be less likely to have spread than larger tumors among patients with asymptomatic lung cancer, suggesting that early screening may be useful in detecting cancers that are still curable, according to a new article.

10-Feb-2006 1:10 PM EST
Estrogen Therapy Does Not Protect Postmenopausal Women from Heart Disease
JAMA - Journal of the American Medical Association

Estrogen therapy does not appear to reduce the risk of heart attack or coronary death in healthy postmenopausal women, although some data suggest a lower coronary heart disease risk in women aged 50 to 59 years, according to a new article.

10-Feb-2006 1:15 PM EST
Treatment to Maintain Blood Pressure in Those with Postural Blood Pressure Drops
JAMA - Journal of the American Medical Association

Use of a medication called pyridostigmine alone or in combination with low-dose midodrine appears to improve standing blood pressure in patients with orthostatic hypotension, a fall in blood pressure associated with postural changes and standing, according to a study.

2-Feb-2006 4:00 PM EST
Low-Fat Diet Has Little Effect on Reducing Risk of Breast Cancer
JAMA - Journal of the American Medical Association

A major study that includes nearly 50,000 women followed over 8 years indicates that a diet low in fat, but high in fruit, vegetables and grains, does not significantly reduce the risk of breast cancer, colorectal cancer or cardiovascular disease in postmenopausal women, according to three articles.

2-Feb-2006 4:00 PM EST
Extremely Low-Birth-Weight Infants Reaching Functional Outcomes
JAMA - Journal of the American Medical Association

The majority of extremely low-birth-weight infants appear to be attaining similar levels of education, employment and independence as young adults, compared with normal birth-weight infants, according to a study.

2-Feb-2006 4:00 PM EST
Lifetime History of Depression Linked with More Brain Plaques, Tangles
JAMA - Journal of the American Medical Association

A lifetime history of depression is associated with increased plaques and tangles in the brains of those with Alzheimer's disease and more rapid cognitive decline, according to a study.

2-Feb-2006 4:00 PM EST
Genetic Factors Important in Development and Timing of Alzheimer’s
JAMA - Journal of the American Medical Association

In a large study of twins, Alzheimer's disease appears to be highly heritable and genetic factors may also influence timing of the disease, according to an article.

2-Feb-2006 4:00 PM EST
Military Trauma Related to Post-war Disease, Death in Civil War Veterans
JAMA - Journal of the American Medical Association

An examination of military archives and medical records indicates that Civil War veterans who watched more of their comrades die or were younger when they entered the military were more likely to develop physical and mental illnesses later in life, and younger soldiers also had a higher risk of early death after the war, according to a study.

1-Feb-2006 4:00 PM EST
Evidence Supports Call Not to Use Certain Type of Anti-viral Drugs for Flu
JAMA - Journal of the American Medical Association

Recent, additional data show that the prevalence of adamantane-resistant influenza A viruses is high across the United States, according to a new study.

19-Jan-2006 4:00 PM EST
Supplemental Radiation Therapy Beneficial for Stage I Endometrial Cancer
JAMA - Journal of the American Medical Association

Women with stage I endometrial cancer (with grade 1 and grades 3 and 4 disease) who receive radiation therapy in addition to other treatment have improved survival rates, according to a study.

19-Jan-2006 4:00 PM EST
Heart Injury Due to Carbon Monoxide Poisoning Increases Long-Term Risk of Death
JAMA - Journal of the American Medical Association

Of patients who were hospitalized and treated for moderate to severe carbon monoxide poisoning, those who sustained heart muscle injury due to their exposure had an increased risk of death during a mid-point follow-up period of 7.6 years compared to those without injury to the heart.

19-Jan-2006 4:00 PM EST
Consumption of Omega-3 Fatty Acids Unlikely to Reduce Cancer Risk
JAMA - Journal of the American Medical Association

A review of numerous studies finds no strong evidence indicating a significantly reduced risk of cancer associated with the consumption of omega-3 fatty acids.

19-Jan-2006 4:00 PM EST
White Blood Cell Count, Inflammation Linked to Cancer Deaths
JAMA - Journal of the American Medical Association

In a study of more than 3,000 older Australians, those with a higher white blood cell count, a sign of inflammation, were more likely to die of cancer, according to an article.

19-Jan-2006 4:00 PM EST
Erectile Dysfunction Common, Linked with Severity of Heart Disease
JAMA - Journal of the American Medical Association

Erectile dysfunction (ED) affects approximately one in five American men, appears to be associated with cardiovascular and other chronic diseases and may predict severity and a poor prognosis among those with heart disease, according to three studies.



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