Overdose mortality among people age 65 and older quadrupled over 20 years, suggesting the need for greater mental health and substance use disorder policies addressed at curbing the trend.
New UCLA research in mice suggests that “dormant” cone photoreceptors in the degenerating retina are not dormant at all, but continue to function, producing responses to light and driving retinal activity for vision.
MitoQ, a mitochondrial antioxidant that is available to the public as a diet supplement, was found in a mouse study to reverse the detrimental effects that HIV and antiretroviral therapy (ART) have on mitochondria in the brain, heart, aorta, lungs, kidney and liver.
Below is a brief roundup of news and story ideas from the experts at UCLA Health. For more information on these stories or for help on other stories, please contact us at [email protected].
A UCLA-led team has developed an inexpensive, universal oral COVID-19 vaccine that prevented severe respiratory illness and weight loss when tested in hamsters, which are naturally susceptible to SARS-CoV-2. It proved as effective as vaccines administered by injection or intranasally in the research. If ultimately approved for human use, it could be a weapon against all COVID-19 variants and boost uptake, particularly in low- and middle-income countries, and among those with an aversion to needles.
Researchers may have found why viral infections hit males more severely than females. They found that female mouse and human NK cells have an extra copy of an X chromosome-linked gene called UTX. UTX acts as an epigenetic regulator to boost NK cell anti-viral function, while repressing NK cell numbers.
A new study represents a first step towards generating highly detailed 3-dimensional maps of lung tumors using genetically engineered mouse models.
Sleeping fewer than six hours per night around the time of vaccination was associated with a robust decrease in antibody response, researchers found.
For the first time, a research team has identified and analyzed the steps by which immune cells “see” and respond to cancer cells, providing insights into reasons some treatments may be effective for certain patients but not others.
Older Black men have a higher chance of dying within 30 days of surgery than do Black women and white men and women – with their odds of death 50% higher after elective surgery compared with white men.
The UCLA Health Homeless Healthcare Collaborative has received a $25.3 million, two-year state grant to expand access and enhance coordination of medical and behavioral health care provided to people experiencing homelessness in Los Angeles.
Today, the WORLD Policy Analysis Center (WORLD) at UCLA, launched “Equality within Our Lifetimes,” the most comprehensive analysis to date of laws and policies related to gender equality in all 193 U.N. member states. While the U.S. performs well in some areas, it has become even more of an outlier when it comes to care.
Patients with higher levels of a key molecule involved in the formation of new blood vessels were more likely to have cognitive impairment or evidence of brain injury, a consortium of academic medical centers reported.
UCLA Health tip sheet: A brief roundup of news and story ideas from the experts at UCLA Health.
A $20 million gift from Andrea and Donald Goodman and Renee and Meyer Luskin will fund a new center at UCLA focused on the microbiome and its effect on health.
Smoking tobacco and vaping electronic cigarettes may increase healthy young people’s risk for developing severe COVID illness.
Many patients don’t receive much rehabilitation therapy following a stroke, despite strong evidence that higher amounts can reduce long-term disability, a large new multi-site study found.
A UCLA-led study provides the first scientific evidence that brick and mortar pharmacies in Northern Mexican tourist towns are selling counterfeit pills containing fentanyl, heroin, and methamphetamine. These pills are sold mainly to US tourists, and are often passed off as controlled substances such as Oxycodone, Percocet, and Adderall.
Implementing financial coaching for parents of infants in a pediatric primary care setting reduced missed well-child care visit rates by half and significantly improved receipt of vaccinations at a timely age, according to a new community-partnered pilot study led by UCLA researchers.
Three years ago this month, the first case of COVID was diagnosed in the United States. Here are the latest figures on the pandemic, collected by UCLA Health hospitals and clinics.
An increase in "deaths of despair" in recent decades has been frequently portrayed as a phenomenon affecting white communities, but a new analysis in The Lancet shows the toll has been greater on Native Americans.
A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing issue in cancer therapeutics. Results are published online ahead of print in Cancer Discovery, a journal of the American Association for Cancer Research.
Below is a brief roundup of news and story ideas from the experts at UCLA Health.
New UCLA-led research suggests that antiretroviral drugs called TAF and TDF directly reduce energy production by mitochondria, structures inside cells that generate the power that cells use to function. Both drugs led to reduced cellular oxygen consumption rates, a measure of the ability of the mitochondria to produce energy, compared with controls.
For men who undergo radiotherapy for localized prostate cancer, the precise targeting capabilities of MRI guidance resulted in fewer toxicities and better quality of life according to new research from UCLA Jonsson Comprehensive Cancer Center.
A brief roundup of news and story ideas from the experts at UCLA Health.
New UCLA-led research finds that a college preparatory program for youth experiencing educational inequities that operates in about 13% of U.S public high schools has a positive effect on students’ social networks, psycho-social outcomes, and health behaviors. The findings, published Dec. 16 in the peer-reviewed journal Pediatrics, suggests that the Advancement via Individual Determination (AVID) program, aimed at increasing educational opportunities for under-represented and economically disadvantaged students, also significantly reduces substance use.
While use of insulin pumps to manage type 1 diabetes has grown over 20 years, there has been no improvement in racial, ethnic, and socioeconomic disparities in their use.
Long COVID patients can experience many of the same lingering negative effects on their physical, mental, and social well-being as those experienced by people who become ill with other, non-COVID illnesses.
A brief roundup of news and story ideas from the experts at UCLA Health.
Many estimates of how strongly traits and diseases share genetic signals may be inflated, and therefore some genetic correlations that have been attributed to shared biology may instead represent incorrect statistical assumptions.
Research finds low-certainty evidence that programs such as emergency rent assistance, legal assistance with waitlist priority for public housing, long-term rent subsidies and homeownership assistance lead to positive health outcomes.
For the first time, scientists have used CRISPR technology to insert genes that allow immune cells to focus their attack on cancer cells, potentially leaving normal cells unharmed and increasing the effectiveness of immunotherapy.
Sex differences in the aging brain may offer an enticing clue for researching more effective neuroprotective treatments, according to a new treatment development strategy laid out by UCLA researchers.
UCLA Health’s Operation Mend will celebrate 15 years of serving post 9/11-era wounded warriors and their families by walking with patients, their family members, physicians, staff, and supporters in the 2022 New York City Veterans Day Parade. They will be joining an estimated 25,000 marchers who gather to honor veterans, raise awareness of those who serve them, and to salute members of our currently serving military.
A team of UCLA researchers has been awarded $20,993,333 by the Los Angeles County Department of Public Health to conduct the Aliso Canyon Disaster Health Research Study.
The new study finds brain-wide changes in virtually all of the 11 cortical regions analyzed, regardless of whether they are higher critical association regions – those involved in functions such as reasoning, language, social cognition and mental flexibility – or primary sensory regions.
New onset chronic kidney disease (CKD) in people with diabetes is highest among racial and ethnic minority groups compared with white persons, a UCLA-Providence study finds. The study, published as a letter to the editor in the New England Journal of Medicine, found that new onset CKD rates were higher by approximately 60%, 40%, 33%, and 25% in the Native Hawaiian/Pacific Islander, Black, American Indian/Alaska Native, and Hispanic/Latino populations, respectively, compared to white persons with diabetes.
New research will aim to identify the electrical activity occurring as the brain receives information and then test whether targeted, gentle electrical stimulation can strengthen a specific memory.
This model can be used by researchers to discover targets for treatments that improve walking, cognitive, coordination and visual disabilities in MS.
Telehealth follow-up consultations following an emergency department visit were associated with 28 more repeat ED encounters and nearly 11 more return hospital admissions per 1000 patients compared with in-person follow-ups,
Preclinical studies in mice that model human COVID-19 suggest that an inexpensive, readily available amino acid might limit the effects of the disease and provide a new off-the-shelf therapeutic option for infections with SARS-CoV-2 variants and perhaps future novel coronaviruses.
In a large analysis of over 7,000 men treated internationally across 12 randomized trials, study shows that it is almost universally optimal for men to begin androgen deprivation therapy when starting radiation.
Research led by doctors and scientists at UCLA Jonsson Comprehensive Cancer Center and the UCLA Jane & Terry Semel Institute for Neuroscience & Human Behavior has identified a gene that may provide a therapeutic target for the deadly, treatment-resistant brain cancer glioblastoma multiforme (GBM).
A majority of health care workers remain antigen positive five to seven days following COVID-19 infection. Other healthcare systems can look to these findings as they implement their own return-to-work testing programs.
A new analysis led by researchers with the University of California has found the 2020 wildfires in the state, the most disastrous wildfire year on record, put twice as much greenhouse gas emissions into the Earth’s atmosphere as the total reduction in such pollutants in California between 2003-2019.
A combination of brain imaging data and machine learning can accurately diagnose obstructive sleep apnea (OSA) significantly faster than the standard methods now in use that are complex, costly, time-consuming, and can delay crucial treatment.
An 8-year study of nearly 1300 low-income adolescents in Los Angeles found that students who attended high performing charter high schools were much less likely to engage in risky substance use by the time they reached age 21. Males who attended the high-performing schools also had better physical health and lower obesity rates as young adults while females had substantially worse outcomes in those two areas.
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