Researchers report that an abbreviated, seven-item scale can help determine with high validity a person’s level of wisdom, a potentially modifiable personality trait that has been shown to have a strong association to well-being.
Novel randomized controlled trial found that families with high consumption of avocados experienced reduced caloric intake and an overall healthier diet, without actually changing their diet.
The California Institute for Regenerative Medicine (CIRM) approved a $4.1 million grant to enable University of California San Diego School of Medicine researchers to advance a new chimeric antigen receptor (CAR) T-cell therapy from the laboratory into the clinic.
Artificial intelligence-based technique reveals previously unknown cell components that may provide new clues to human development and disease.
UC San Diego researchers have produced a single-cell chromatin atlas for the human genome. Delineating chromatin regions in cells of different human tissue types would be a major step toward understanding the role of gene regulatory elements (non-coding DNA) in human health or disease.
A novel study — led by University of California San Diego and UCLA, in collaboration with the La Jolla Institute for Immunology — is assessing whether medicinal mushrooms and Chinese herbs provide therapeutic benefit in treating acute COVID-19 infection.
Researchers reveal a previously unrealized complexity in cancer development, one that raises concerns and caution about targeting an enzyme popular in oncological treatments.
Neuroimaging study reveals potential brain mechanism underlying chronic neuropathic pain in individuals with HIV. Findings may guide new clinical treatments targeting patients’ expectations for pain relief.
A new $9 million grant from Aligning Science Across Parkinson’s (ASAP) will enable advancement of UC San Diego’s discovery that inhibiting a single gene in mice converts other cell types directly into new neurons, alleviating all Parkinson’s symptoms.
University of California San Diego researchers, with international colleagues, describe how energy expenditure and heat production are regulated in obesity through a previously unknown cellular pathway.
Researchers at University of California San Diego School of Medicine tested the same treatment for kids with Kawasaki disease and rare COVID-19 reaction.
University of California San Diego researchers describe how a pair of fundamental genetic and cellular processes — aneuploidy and unfolded protein response — are exploited by cancer cells to promote tumor survival and growth.
Philanthropists Richard and Carol Dean Hertzberg have committed $2.1 million to develop and maintain the Dean-Hertzberg Breast Cancer Database System Initiative at UC San Diego Health Moores Cancer Center to support the work of Anne Wallace, MD and her collaborators at Moores Cancer Center.
A new trial by UC San Diego Health infectious disease specialist Maile Young Karris, MD, will use longitudinal questionnaires and qualitative interviews to assess the impact of living in an interconnected virtual village on the loneliness known to afflict older people with HIV.
In novel study, an international research team investigated whether continued magnetic seizure therapy might effectively prevent the relapse of treatment-resistant depression, compared to what is known about electroconvulsive therapy, the current standard of care.
An international team of researchers has broadened and deepened understanding of how inherited retinal dystrophies (IRDs) affect different populations of people and, in the process, have identified new gene variants that may cause the diseases.
Researchers at UC San Diego School of Medicine identify a strain of bacteria on healthy cats that produces antibiotics against severe skin infections. The findings may soon lead to new bacteriotherapies for humans and their pets, wherein cat bacteria is applied via topical cream or spray.
Leaders in cell biology and anti-malarial drug development respectively, JoAnn Trejo and Elizabeth Winzeler were recognized by their peers with one of the highest honors in health and medicine.
The National Institutes of Health (NIH) has awarded researchers at University of California San Diego approximately $30 million over five years to expand and deepen longitudinal studies of the developing brain in children.
UC San Diego Health announces it has been recognized as a top performer in the 2021 Bernard A. Birnbaum, MD, Quality Leadership Annual Ranking by Vizient Inc.
UC San Diego researchers report that conducting genomic evaluations of advanced malignancies can be effective in guiding first-line-of-treatment, rather than waiting until standard-of-care therapies have failed.
Jacobs Medical Center at UC San Diego Health marks its fifth anniversary and celebrates achievements and milestones while providing the most advanced medical and surgical care in the region.
Researchers at UC San Diego School of Medicine awarded $11.7 million by National Institutes of Health to identify genomic and socioeconomic factors contributing to health and disease in admixed individuals. The new center aims to bring the genomic revolution to all.
More than 100 UC San Diego Health physicians in 48 specialties have been named “Top Docs” in the 2021 San Diego Magazine “Physicians of Exceptional Excellence” survey.
Multisystem inflammatory syndrome in children (MIS-C) is a serious condition associated with a recent COVID-19 infection.
In a special issue of Nature, UC San Diego researchers further refine the organization of cells within key regions of the mouse brain and the organization of transcriptomic, epigenomic and regulatory factors that provide these brain cells with function and purpose.
In three Science papers, UC San Diego and UC San Francisco researchers mapped out how hundreds of gene mutations involved in cancer affect the discrete groups of proteins that are the ultimate actors behind the disease. The work points the way to identifying new precision treatments.
International group of researchers identify new childhood genetic condition and a potential cure that can be delivered during pregnancy.
Researchers describe how withdrawal from nicotine, methamphetamine and cocaine alters the functional architecture and patterns in the brains of mice, compared to control animals, a key to developing addiction treatments.
UC San Diego School of Medicine receives $6.1M to launch a new research center studying the effects of maternal antibiotic use on breast milk and infant health. The center is funded by National Institutes of Health, as part of their new Maternal and Pediatric Precision in Therapeutics (MPRINT) Hub.
UC San Diego School of Medicine researchers will receive $6.4 million in National Institutes of Health grant funding to study how external signals and genetic variations influence the behavior of one cell type in particular: insulin-producing beta cells in the pancreas.
Researchers found that breastfeeding mothers who received either the Pfizer-BioNTech or Moderna vaccination reported the same local or systemic symptoms as what has been previously reported in non-breastfeeding women, with no serious side effects in the breastfed infants.
UC San Diego Health improved care for more than 32,000 Medicare beneficiaries in San Diego, Riverside, and Imperial Counties, and saved Medicare close to $7 million by utilizing population health technologies to exceed quality and cost goals in 2020.
After experiencing a medical emergency, Don Cohn is giving back to the department that he credits with saving his life.
UC San Diego School of Medicine receives $2.6M to fund their PRIME-Health Equity program and launch a new program on Native American health. These medical education programs provide financial support to medical students interested in addressing health disparities and serving local communities.
From tele-monitoring patients with diabetes to using artificial intelligence to prevent sepsis, the newly launched Center for Health Innovation will seek to develop, test and commercialize technologies that make a real, measurable difference in the lives and wellbeing of patients.
A study measured effectiveness of COVID-19 mRNA vaccines among health workers, most notably during the emergence of delta virus variant and coincident with end of state’s mask mandate, finding protection waned over time, dropping sharply 6-8 months after full vaccination.
UC San Diego is collaborating with San Ysidro Health on an NIH-funded outreach program to address COVID-19 vaccine hesitancy in Latinx and African American communities. The team runs pop-up vaccination sites across San Diego, and goes door-to-door to homes and local businesses to spread awareness.
Lab studies reveal protein HSP27’s role in blood vessel leakage, opening the possibility that therapeutically dialing its activity up or down might stabilize patients with sepsis.
UC San Diego researchers developed first-of-their-kind lung organoids that include all cell types that make up the organ, allowing for “Phase 0” testing of new treatments for respiratory infections such as COVID-19.
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