Researchers at Harvard Medical School, the University of California, San Francisco, and the University of Georgia have described how the protein that allows strep and staph bacteria to stick to human cells is prepared and packaged. The research, which could facilitate the development of new antibiotics, will appear in the April 6 issue of the Journal of Biological Chemistry.
The 2018 ASBMB Annual Meeting in San Diego will feature talks by winners of the Journal of Biological Chemistry/Herbert Tabor Young Investigator Awards, on April 22.
Cells can avoid “data breaches” when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert Einstein College of Medicine have shown. Their study appears in the March 23 issue of the Journal of Biological Chemistry.
The Journal of Biological Chemistry has appointed Phyllis Hanson, Karin Musier-Forsyth, and Michael Shipston as associate editors. The three new editors bring expertise in intracellular cell membranes, RNA biology, and ion channel signaling to the journal.
Research Highlights: a proteomics study to understand a rare skin disease; understanding T cell activation through "click chemistry."
Researchers at Iowa State University, partnering with the LifeServe Blood Center, have used leftover blood donor cells to gain crucial insights into how natural killer cells circulating in the human body differ from those typically studied in the lab. The results of this research are published in the March 9 issue of the Journal of Biological Chemistry.
A lotion inspired by babies’ skin, membrane binding by an inflammation-linked kinase, and a colorectal cancer-fighting microRNA.
Researchers at Durham University in the UK have identified a crucial link in the process of how plants regulate their antiviral responses. The research is published in the March 2 issue of the Journal of Biological Chemistry.
New research published in the Feb. 23 issue of the Journal of Biological Chemistry identifies an enzyme that turns off transglutaminase 2, potentially paving the way for new treatments for celiac disease.
NIH researchers studying a fatal childhood illness called Sandhoff disease uncover new details about how it develops in utero that indicate gene therapy has potential.
Researchers studying half-lives of evolutionarily related proteins in different species uncovered a link between species lifespan and protein lifespan.
Cholesterol in muscular dystrophy; synergy between alcohol and hepatitis in cholesterol levels; bacterial lipids in healthy arteries.
Researchers at the University of Georgia have now shown that the enzyme that makes the El Tor family of V. cholerae resistant to those antibiotics has a different mechanism of action from any comparable proteins observed in bacteria so far. Understanding that mechanism better equips researchers to overcome the challenge it presents in a world with increasing antibiotic resistance. The results of this research are published in the Dec. 22, 2017 issue of the Journal of Biological Chemistry.
Researchers at the California Institute of Technology have developed an approach to overcome a major stumbling block in testing new drug targets. The research is reported in a Nov. 24 paper in the Journal of Biological Chemistry.
Qi-Qun Tang, a professor of in the department of biochemistry and molecular biology at the Fudan University School of Basic Medical Sciences in Shanghai, China, has joined the Journal of Biological Chemistry as an associate editor.
A research project that began 20 years ago with an interest in how lithium treats mood disorders has yielded insights into the progression of blood cancers such as leukemia. The research, which centers on a protein called GSK-3, will be published in the Nov. 3 issue of the Journal of Biological Chemistry.
In an opinion piece in the journal eLife, eight scientists and science policy experts make the case for standardizing how postdoctoral researchers are categorized by human resources offices and provide a framework that willing institutions can follow.
Ursula Jakob, a professor of biological chemistry at the University of Michigan, has joined the Journal of Biological Chemistry as an associate editor.
New research from the Korea Institute of Science and Technology, to be published in the Journal of Biological Chemistry on Oct. 13, has found that the proteasome, an essential protein complex that breaks down proteins in cells, has another unexpected function: directly regulating the packing of DNA in the nucleus.
New insight into how the protein antithrombin works could lead to treatments not only for patients with antithrombin deficiency, but also to better-designed drugs for other blood disorders.
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