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Released: 9-Feb-2017 8:00 AM EST
Using a Printed 3-D Model as a Guide, Cardiologist Creates a Modified Stent to Repair a Toddler’s Pulmonary Artery and Gives a Family Hope
Children's Hospital Los Angeles

Using a printed 3-D model as a guide, a Children’s Hospital Los Angeles cardiologist specially modified a stent to repair an 18-month-old’s narrowed pulmonary artery.

3-Feb-2017 6:00 AM EST
Less Is More: Exposure to Stimuli for Overcoming Phobia
Children's Hospital Los Angeles Saban Research Institute

A team of investigators, led by Bradley S. Peterson, MD, director of the Institute for the Developing Mind at Children’s Hospital Los Angeles, and Paul Siegel, PhD, associate professor of psychology at Purchase College of the State University of New York, have found that exposure to phobic images without conscious awareness is more effective than longer, conscious exposure for reducing fear.

24-Jan-2017 6:00 AM EST
Short Bowel Syndrome Results in Changes to Gene Expression
Children's Hospital Los Angeles Saban Research Institute

Investigators at Children’s Hospital Los Angeles, led by Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short bowel syndrome (SBS) using a novel zebrafish model and by performing intensive gene sequencing. This approach to determining which genes are markedly over or under expressed in SBS may assist scientists in developing future therapies for children and adults with this condition.

Released: 12-Jan-2017 2:05 PM EST
Philippe Friedlich Named Division Chief at Children’s Hospital Los Angeles
Children's Hospital Los Angeles

Philippe Friedlich, MD, MSEpi, MBA, has been selected as division chief of Neonatology and director of the Center for Fetal and Neonatal Medicine (CFNM) at Children’s Hospital Los Angeles.

Released: 10-Jan-2017 3:05 PM EST
Children’s Hospital Los Angeles Awarded Nearly $1 Million From Department of Health
Children's Hospital Los Angeles

The USC University Center of Excellence on Developmental Disabilities (UCEDD) at Children’s Hospital Los Angeles was awarded $880,000 from the Los Angeles County Department of Public Health with funding from the California Department of Public Health and the United States Department of Agriculture.

Released: 3-Jan-2017 2:05 PM EST
Stuttering Linked to Reduced Blood Flow in Area of Brain Associated with Language
Children's Hospital Los Angeles Saban Research Institute

A study led by researchers at Children’s Hospital Los Angeles demonstrates what lead investigator Bradley Peterson, MD, calls “a critical mass of evidence” of a common underlying lifelong vulnerability in both children and adults who stutter.

Released: 29-Dec-2016 7:05 PM EST
300… and Counting! Children's Hospital Los Angeles Performs Milestone Liver Transplant
Children's Hospital Los Angeles

Children's Hospital Los Angeles performs milestone 300th pediatric liver transplant when father donates tissue to son; family also gets a visit from CHLA's first-ever living donor liver patient.

28-Dec-2016 9:00 AM EST
Providence Saint John’s and Children’s Hospital Los Angeles Medical Group to Provide the Highest Level Care for Fragile Newborns
Children's Hospital Los Angeles

Providence Saint John’s Health Center is partnering with Children’s Hospital Los Angeles Medical Group to raise the level of neonatal care in Santa Monica and surrounding Westside communities.

Released: 2-Dec-2016 10:05 AM EST
Treatment Significantly Reduces Chemotherapy-Induced Hearing Loss in Children
Children's Hospital Los Angeles

Investigators from Children’s Hospital Los Angeles and 37 other Children’s Oncology Group hospitals in the U.S. and Canada have determined that sodium thiosulfate prevents cisplatin-induced hearing loss in children and adolescents with cancer. Results of this randomized, controlled, phase 3 study, called ACCL0431, have been published in the early online edition of Lancet Oncology.

Released: 23-Nov-2016 12:05 PM EST
Stuttering Related to Brain Circuits That Control Speech Production
Children's Hospital Los Angeles Saban Research Institute

Researchers at Children’s Hospital Los Angeles (CHLA) have conducted the first study of its kind, using proton magnetic resonance spectroscopy (MRS) to look at brain regions in both adults and children who stutter.

21-Nov-2016 12:05 PM EST
Biomarker Identified to Aid in Prognosis of Pediatric Ependymomas
Children's Hospital Los Angeles

A multi-institutional group of researchers, led by investigators at Children’s Hospital Los Angeles and the University of Michigan, have identified a simple and inexpensive tool for assessing the prognosis of pediatric brain tumors called ependymomas.

Released: 11-Nov-2016 1:05 PM EST
Scientists Develop Tissue-Engineered Model of Human Lung and Trachea
Children's Hospital Los Angeles Saban Research Institute

Scientists at Children’s Hospital Los Angeles have developed a tissue-engineered model of lung and trachea which contains the diverse cell types present in the human respiratory tract. The study was published this week in the online version of the journal Tissue Engineering.

Released: 10-Nov-2016 3:05 PM EST
Researchers at Children’s Hospital Los Angeles Receive Grant to Study New Way of Battling Resistant Cancer Cells
Children's Hospital Los Angeles Saban Research Institute

Yong-Mi Kim, MD, PhD, of Children’s Hospital Los Angeles, has been awarded a 3 year translational research program grant from the Leukemia & Lymphoma Society to study a novel approach to eradicating minimal residual disease in patients with acute lymphoblastic leukemia (ALL).

Released: 10-Nov-2016 2:05 PM EST
Children’s Hospital Los Angeles Expert Available to Speak on Sudden Acute Flaccid Myelitis Spike
Children's Hospital Los Angeles

A rare neurological disease has recently taken center stage in the United States. Acute flaccid myelitis (AFM) has been identified by the Centers for Disease Control and Prevention (CDC) as the cause of eight hospitalizations in the Seattle-area alone, all of which involved children with polio-like symptoms. As of September 2016, 89 people in 33 states were confirmed to have AFM, with the CDC expressing concern about the sharp spike in cases in recent months.

Released: 20-Oct-2016 12:05 PM EDT
Rac1 Protein Critical for Lung Development
Children's Hospital Los Angeles Saban Research Institute

A study by researchers from The Saban Research Institute of Children’s Hospital Los Angeles reveals a promising therapeutic target for improving lung function in infants.

Released: 18-Oct-2016 3:05 PM EDT
Children’s Hospital Los Angeles Awarded Grant to Study Immunotherapy Resistance in Neuroblastoma
Children's Hospital Los Angeles Saban Research Institute

A team of investigators at Children’s Hospital Los Angeles has received a major, three-year grant from the V Foundation for Cancer Research to study the effects of chemoimmunotherapy in children with neuroblastoma.

Released: 17-Oct-2016 12:05 PM EDT
Oncoproteins Interact to Promote Cancer Cell Growth in Retinoblastoma
Children's Hospital Los Angeles Saban Research Institute

Researchers at The Saban Research Institute of Children’s Hospital Los Angeles have identified an unsuspected and critical role of the MDM2 oncogene in promoting expression of the MYCN oncogene that is required for growth and survival of retinoblastoma cells. Their results are published in the October 17 online edition of the Nature journal Oncogene.

Released: 11-Oct-2016 2:05 PM EDT
Combination Therapy Shows Promise in Fighting Neuroblastoma
Children's Hospital Los Angeles Saban Research Institute

A study by a multidisciplinary team of researchers from Children’s Hospital Los Angeles sheds further light on the role of the cytokine TGFβ1 in the growth of neuroblastoma, and suggests the possibility for a small molecule drug/antibody combinatorial therapy to treat this cancer.

Released: 14-Sep-2016 12:05 PM EDT
Researcher at Children’s Hospital Los Angeles Awarded $2.3 Million From Department of Defense
Children's Hospital Los Angeles Saban Research Institute

David Warburton, MD, of Children’s Hospital Los Angeles (CHLA) has been awarded more than $2.3 million from the Department of Defense for the development of an innovative endoscopic device for performing noninvasive, quantitative analysis of lung epithelial cell metabolism during lung injury.

Released: 12-Sep-2016 6:00 AM EDT
Human Kidney Progenitors Isolated, Offering New Clues to Cell Renewal
Children's Hospital Los Angeles Saban Research Institute

In a first-of-its-kind look at human kidney development, researchers at The Saban Research Institute of Children’s Hospital Los Angeles have isolated human nephron progenitor (NP) cells. Their results may offer a future way to foster renal regeneration after chronic kidney failure or acute injury.

Released: 1-Sep-2016 2:05 PM EDT
Genetic Intersection of Neurodevelopmental Disorders and Shared Medical Conditions
Children's Hospital Los Angeles

Researchers at the Institute for the Developing Mind at Children’s Hospital Los Angeles have analyzed current gene-disease findings to understand why people with neurodevelopmental and mental illness often have physical disorders.

26-Aug-2016 5:05 PM EDT
Functional Human Tissue-Engineered Liver Generated From Stem and Progenitor Cells
Children's Hospital Los Angeles

A research team at Children’s Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells. Tissue-engineered Liver (TELi) was found to contain normal structural components such as hepatocytes, bile ducts and blood vessels.

Released: 24-Aug-2016 6:00 AM EDT
Children’s Hospital Los Angeles Receives Top Epilepsy Ranking From the National Association of Epilepsy Centers
Children's Hospital Los Angeles

Children’s Hospital Los Angeles (CHLA) has been recognized by the National Association of Epilepsy Centers (NAEC) as a Level 4 epilepsy center, providing the highest–level medical and surgical evaluation and treatment for patients with complex epilepsy.

Released: 15-Aug-2016 6:05 PM EDT
More Than 200 Physicians From Children’s Hospital Los Angeles Named to Pasadena Magazine’s Top Doctors List
Children's Hospital Los Angeles

This year, Pasadena Magazine's prestigious Top Doctors issue recognizes more than 200 physicians with privileges to practice at Children’s Hospital Los Angeles, a top-ranked U.S. pediatric academic medical center.

Released: 15-Aug-2016 12:05 PM EDT
Pulmonary Complications in Adult Survivors of Childhood Cancer
Children's Hospital Los Angeles

A team of researchers have published a paper in the early online edition of the journal Cancer that describes pulmonary outcomes among childhood cancer survivors. The study evaluates the impact of complications such as asthma, chronic cough, emphysema and recurrent pneumonia on daily activities.

Released: 9-Aug-2016 2:05 PM EDT
Children’s Hospital Los Angeles Specialists Offer Top Five Back to School Tips for Parents and Kids
Children's Hospital Los Angeles

With a little advance planning, going back to school can be a fun and exciting adventure for kids and parents. The specialists at Children’s Hospital Los Angeles (CHLA) have put together their top five tips to ensure parents and kids transition smoothly from summer vacation to the new school year.

Released: 5-Aug-2016 11:05 PM EDT
Doctors, Nurses and Staff Host a Sneak Preview Quinceanera Celebration for Formerly Conjoined Guatemalan Twins Josie Hull and Teresa Cajas
Children's Hospital Los Angeles

Doctors, nurses and staff at Children’s Hospital Los Angeles (CHLA) got a special treat earlier this week – a sneak preview of the Quinceanera gowns worn by two very special patients – formerly conjoined twins Josie Hull and Teresa Cajas. The girls were famously separated at the skull in a surgery in 2002.

Released: 2-Aug-2016 5:05 PM EDT
Glucose Transporters Blocked in Bacterial Meningitis
Children's Hospital Los Angeles

CHLA researchers report that glucose transporters, which transfer glucose from the blood to the brain, are inhibited by E. coli K1 during bacterial meningitis, leaving insufficient fuel for immune cells to fight off infection. Their findings may lead to a novel way of treating children with meningitis and reducing long-term neurological problems.

25-Jul-2016 12:00 PM EDT
Maternal HIV Status May Disrupt Normal Microbiome Development in Uninfected Infants
Children's Hospital Los Angeles

A study led by researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) suggests that maternal HIV infection influences the microbiome of their HIV-uninfected infants. Their findings may account for some of the immunological and survival differences seen these children.

Released: 25-Jul-2016 1:05 PM EDT
DNA Sequencing Uncovers Latent Risk for Developing Cystic Fibrosis
Children's Hospital Los Angeles

A new research study suggests that all babies with a known mutation for cystic fibrosis (CF) and second mutation called the 5T allele should receive additional screening in order to better predict the risk of developing CF later in life.

Released: 8-Jul-2016 1:05 PM EDT
NIH Awards USC and CHLA $36.6 Million for Clinical and Translational Science
Childrens Hospital Los Angeles and Keck Medicine of USC

A team of researchers led by Thomas Buchanan, MD, Michele Kipke PhD and Jonathan Samet, MD, of the Keck School of Medicine of the University of Southern California (USC) received a prestigious Clinical and Translational Science Award (CTSA) from the National Institutes of Health (NIH). The award was made to USC and Children’s Hospital Los Angeles (CHLA).

Released: 7-Jul-2016 11:05 AM EDT
The Steven & Alexandra Cohen Foundation Donates $3 Million to Name Children’s Hospital Los Angeles Neonatal Unit
Children's Hospital Los Angeles

On behalf of their charitable foundation, investor Steven Cohen and his wife Alexandra have donated $3 million to Children’s Hospital Los Angeles (CHLA) in support of the hospital’s neonatal unit. In honor of the couple’s generous gift, the unit will be named the Steven & Alexandra Cohen Foundation Newborn and Infant Critical Care Unit.

Released: 28-Jun-2016 11:05 AM EDT
Nancy Lee, RN, MSN, NEA-BC, Joins Children’s Hospital Los Angeles as Senior Vice President and Chief Clinical Officer
Children's Hospital Los Angeles

Nancy Lee, RN, MSN, NEA-BC, will join Children’s Hospital Los Angeles (CHLA) as senior vice president and chief clinical officer (CCO), effective July 5, 2016.

Released: 22-Jun-2016 2:05 PM EDT
Children's Hospital Los Angeles Concussion Expert Available to Speak on Kids and Concussions Study
Children's Hospital Los Angeles

Tracy Zaslow, MD, is the director of the Sports Concussion Program and medical director of the Sports Medicine Program. She is Board-Certified in pediatrics, and also fellowship-trained, with board certification in sports medicine. Her clinical interests include a spectrum of orthopaedic and medical conditions affecting young athletes, including sports-related concussion, overuse injuries and injury prevention.

Released: 21-Jun-2016 3:05 PM EDT
Summer Safety
Children's Hospital Los Angeles

With summer comes fun in the sun, beach outings, pool parties and outdoor adventures like camping, hiking, bicycling and skateboarding. What also comes is an increased risk for injuries and as such, an increased need for awareness. The specialists at Children’s Hospital Los Angeles have compiled a list of helpful guidelines to ensure that you and your family have an enjoyable and safe summer in the heat and in and around the water.

Released: 21-Jun-2016 12:30 AM EDT
For the Eighth Consecutive Year, This California Pediatric Medical Facility Ranks in the Top 10 nationally in the U.S. News & World Report Best Children's Hospitals Honor Roll
Children's Hospital Los Angeles

U.S. News & World Report today has ranked Children’s Hospital Los Angeles once again as one of the best children’s hospitals in the United States, and as the top pediatric medical center in California, in the 2016-17 survey of best children's hospitals.

Released: 20-Jun-2016 9:00 AM EDT
Fear Factor: A New Genetic Candidate for Treating PTSD
Children's Hospital Los Angeles

Researchers at The Saban Research Institute of Children’s Hospital Los Angeles have identified a new genetic candidate for testing therapies that might affect fear learning in people with PTSD or other conditions. Results of the study have been published in the Journal of Neuroscience.

Released: 15-Jun-2016 11:05 AM EDT
Six Summer Essentials for Families to Follow
Children's Hospital Los Angeles

While it’s important for children of all ages to embrace the down time away from the high expectations and heavy workloads of being in school, summer is not necessarily the time to abandon a structured schedule and learning opportunities. Here are a few tips for families to follow to help make this summer season productive and enjoyable.

Released: 14-Jun-2016 12:05 PM EDT
New Insights Uncovered Into Prader-Willi Syndrome
Children's Hospital Los Angeles

A study published in the journal Human Molecular Genetics by researchers at Children’s Hospital Los Angeles (CHLA) provides novel insights into the brain mechanisms underlying the insatiable hunger and subsequent obesity in patients with Prader-Willi syndrome.

Released: 13-Jun-2016 1:05 PM EDT
Culture Crash: How Common Pediatric Diseases Affect the Healthy Intestinal Microbiome
Children's Hospital Los Angeles

Since the intestinal microbiome is an important regulator of gut health and immune function, a pediatric surgeon and principal investigator at Children’s Hospital Los Angeles , investigated how surgical treatment of certain pediatric intestinal diseases have a long-term impact on intestinal flora.

Released: 7-Jun-2016 4:05 PM EDT
Study Sheds Light on Uncategorized Genetic Mutations in Cystic Fibrosis
Children's Hospital Los Angeles

A new study led by researchers at Children’s Hospital Los Angeles and the Genetic Disease Screening Program of the California Department of Public Health sheds light on some of those genetic mutations and the impact for those who carry them.

Released: 10-May-2016 3:05 PM EDT
Paul S. Viviano Named 2016 Leader of Today Honoree by the Health Policy and Management Alumni Association of the UCLA Fielding School of Public Health
Children's Hospital Los Angeles

Recognizing his decades of health care leadership, the Health Policy and Management Alumni Association of UCLA’s Fielding School of Public Health has selected Children’s Hospital Los Angeles President and CEO Paul S. Viviano as its 2016 Leader of Today Honoree.

Released: 10-May-2016 9:00 AM EDT
Pediatric Surgery – Conditions That Once Required Surgery Can Now Be Treated with Outpatient Procedures
Children's Hospital Los Angeles

General pediatric surgical care can now be administered at outpatient centers specializing in the care and treatment of children

Released: 9-May-2016 2:05 PM EDT
CHLA Named One of the “100 Great Hospitals in America” by Becker’s Hospital Review
Children's Hospital Los Angeles

Becker's Hospital Review announced that Children’s Hospital Los Angeles (CHLA) earned a coveted place in its 2016 edition of its list of "100 Great Hospitals in America."

Released: 5-May-2016 8:05 PM EDT
Veteran Night Shift Oncology Nurse: "I Still Love My Job"
Children's Hospital Los Angeles

Tommy Covington is the kind of caretaker that his colleagues admire and his patients and families adore. Covington, a soft-spoken, teddy-bear-like veteran, is a legend at CHLA where he works the night shift (7 pm to 7 am) on the hematology-oncology floor. He and the rest of the CHLA nursing staff will be celebrated during National Nurses Week, May 6-12.

Released: 26-Apr-2016 12:05 PM EDT
Children’s Hospital Los Angeles Inaugural Make March Matter Campaign Raises $1.3 Million
Children's Hospital Los Angeles

LOS ANGELES (April 26, 2016) – The inaugural Children’s Hospital Los Angeles Make March Matter ™ campaign raised $1.3 million, the hospital announced Tuesday. The month-long initiative exceeded its $1 million fundraising goal thanks to 67 local businesses and corporate partners who rallied community participation to give in support of critical, lifesaving care for children in Los Angeles.

Released: 14-Apr-2016 5:05 PM EDT
Combination Therapy May Offer Better Outcomes for Patients with Retinoblastoma
Children's Hospital Los Angeles

Researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) have demonstrated that targeting survivin – a protein that inhibits apoptosis or cell death – enhances the effectiveness of chemotherapy in cells and mouse models of retinoblastoma (Rb).

Released: 11-Apr-2016 7:05 PM EDT
Children’s Hospital Los Angeles Unleashes Fun with Inaugural Dog Therapy Appreciation Day
Children's Hospital Los Angeles

What could be warmer and fuzzier than a cute dog? How about 20 of them gathered together at a ‘pawty’ to celebrate a milestone occasion? That’s what happened when Children’s Hospital Los Angeles declared Monday to be Dog Therapy Appreciation Day. The hospital’s Amerman Family Foundation Dog Therapy Program marked a first by providing 365 consecutive days of dog therapy to CHLA patients, families and staff. The last day without a therapy dog on the CHLA campus was April 10, 2015.

Released: 11-Apr-2016 5:05 PM EDT
CHLA Researcher Awarded $1.665 Million to Study Retinal Development
Children's Hospital Los Angeles

David E. Cobrinik, MD, PhD, of The Vision Center at Children’s Hospital Los Angeles (CHLA) has been awarded a four-year grant totaling $1.665 million from the National Eye Institute of the National Institutes of Health. The grant will support his study seeking to improve understanding of how cone photoreceptors develop.



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