Reanalyses of Data From RCTs Can Lead to Different Conclusions
JAMA - Journal of the American Medical AssociationAlthough only a small number of reanalyses of data from randomized clinical trials (RCTs) have been published, an examination of those that have been conducted finds that about one-third led to changes in findings that implied conclusions different from those of the original article regarding the types and number of patients who should be treated, according to a study in the September 10 issue of JAMA.