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Irvine, Calif., Jan. 11, 2022 — Orange County will be home to new youth drop-in centers offering wellness services to those between the ages of 12 and 25. Endorsed by Orange County to apply for a $2 million grant from California’s Mental Health Services Oversight & Accountability Commission, the University of California, Irvine will partner with the Wellness & Prevention Center in south Orange County to establish and administer youth drop-in centers following the allcove model.

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A $3 million gift to the University of California, Irvine from the Sue J. Gross Foundation will expand training and education opportunities in the Sue & Bill Gross School of Nursing, which was established by a naming gift from The William and Sue Gross Family Foundation, where Sue Gross served as co-founder and director.

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Irvine, Calif., Jan. 10, 2022 – A team led by University of California, Irvine researchers has developed a new biopsy technology that can profile multiple tumor microenvironment biomarkers simultaneously, revealing cellular spatial organization and interactions that will help advance personalized disease diagnosis and treatment.

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A research team led by University of California, Irvine has discovered new neural circuits that regulate spatial learning and memory in the brain’s hippocampal formation. The team identified novel functional roles of new circuit connections between the venal CA1 region and dorsal CA3 regions of the hippocampus and demonstrated that genetic inactivation of this projection impairs object-related spatial learning and memory, but does not modulate anxiety-related behaviors.

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For the first time, University of California, Irvine researchers in collaboration with the Max-Planck Institute of Biochemistry, have revealed, at a molecular level, key structural determinants of the highly specialized rod outer segment (ROS) membrane architecture of the eye, which is instrumental to vision.

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Videogame research and development experts at the University of California, Irvine are inviting the world’s gaming community to the Games + Learning + Society Conference to be held June 15 to 17, 2022, on the UCI campus.

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The brain is a battlefield where cognitive domains vie for limited resources, and this appears to be particularly true during sleep.

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Irvine, Calif., Dec. 13, 2021 — A naming gift from Jack and Shanaz Langson to the University of California, Irvine will support the construction and operation of a state-of-the-art building facility to house the Institute and Museum of California Art and its important collection of California art. In recognition of their generous support, IMCA will be named the Jack and Shanaz Langson Institute and Museum of California Art.

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Michael Méndez, UCI assistant professor of urban planning & public policy, first started to dream of attending a United Nations Climate Change Conference during the three years he served as an inaugural James & Mary Pinchot Fellow in Sustainability Studies at the Yale School of the Environment. The fellowship resulted in his award-winning book, Climate Change From the Streets: How Conflict and Collaboration Strengthen the Environmental Justice Movement (Yale University Press, 2020).

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A new study led by University of California, Irvine researchers has confirmed a link between altered DNA repair and increased DNA damage associated with spinocerebellar ataxia type 7 (SCA7), a debilitating, sometimes deadly neurodegenerative condition causing movement disorders. Their work also revealed a potential therapeutic target for the currently incurable and difficult to treat condition.

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The international Forward Search Experiment team, led by physicists at the University of California, Irvine, has achieved the first-ever detection of neutrino candidates produced by the Large Hadron Collider at the CERN facility near Geneva, Switzerland.

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Naturalist John Muir called the Sierra Nevada “the Range of Light.” But a more ominous nickname, “the Range of Fire,” may lie ahead, according to new research from the University of California, Irvine. By 2040, as humans continue to change the climate, fire-conducive heat waves will become so common that the number of blazes throughout the Sierra stands to increase about 50 percent, researchers found.

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Imagine your car starting the moment you get in because it recognizes the jacket you’re wearing. Consider the value of a hospital gown that continuously measures and transmits a patient’s vital signs. These are just two applications made possible by a new “body area network”-enabling fabric invented by engineers at the University of California, Irvine.

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In a University of California, Irvine-led study, researchers revealed a striking pattern following a functional screen of extracts from plants collected in Muir Woods National Monument, in coastal redwood forest land in California. They found plants with a long history of use by Native Americans as topical analgesics, were often also used as gastrointestinal aids.

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The University of California, Irvine Center for Neural Circuit Mapping (CNCM) has been awarded three new grants: a four year, $4.8M grant from the National Institute on Aging; a three year, $1.8M grant from the Food and Drug Administration (FDA); and, a one year, $.5M grant from the National Institute of Mental Health. The grants will support the efforts of CNCM Investigators to develop powerful new molecular tools and will enhance resources offered by the Center to neurosciences researchers worldwide.

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PIEZO1, an ion channel mechanosensor found within cells, has been revealed to play a key role in regulating the speed of skin wound healing by researchers at the University of California, Irvine (UCI).

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With the eyes of the world on the United Nations COP26 climate summit in Glasgow, Scotland, strategies for decarbonizing energy infrastructure are a trending topic. Yet critics of renewables question the dependability of systems that rely on intermittent resources. A recent study led by researchers at the University of California, Irvine tackles the reliability question head-on.

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University of California, Irvine and Children’s Health of Orange County (CHOC) have been jointly designated a National Organization for Rare Disorders (NORD) Center of Excellence, joining a new and highly select group of 31 medical centers seeking to expand access and advance care and research for rare disease patients in the United States.

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Michael Méndez, assistant professor of urban planning & public policy at the University of California, Irvine, will moderate a press conference on California’s approach to integrating environmental justice into climate solutions at 1:15 p.m. GMT on Monday, Nov. 8, at the 2021 United Nations Climate Change Conference being held in Glasgow, Scotland.

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More than four times as many businesses and clinics than were identified in 2016 are selling stem cell products not approved by the U.S. Food and Drug Administration and lack convincing evidence of safety and efficacy, according to a five-year study conducted by University of California, Irvine Program in Public Health professor of health, society and behavior Leigh Turner. The analysis appears online in the journal Cell Stem Cell.

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The National Science Foundation has awarded almost $3 million over a five-year period to The Institute for Meaningful Engagement at the University of California, Irvine. This new education project will explore the environmental factors prompting underrepresented students to leave science, technology, engineering and math programs and investigate how faculty can foster better classroom cultures to retain them. A multidisciplinary leadership team will partner with the deans of UCI’s six STEM schools to accomplish this.

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For a second time, the University of California, Irvine has achieved a rare platinum rating through the Association for the Advancement of Sustainability in Higher Education’s Sustainability Tracking, Assessment & Rating System, maintaining its status as one of the environmentally outstanding universities in the world.

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The University of California, Irvine Division of Continuing Education invites recent alumni to apply to Netflix Pathways Boot Camps.

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Days before the opening of the 26th Conference of the Parties to the United Nations Framework Convention on Climate Change in Glasgow, Scotland, the latest estimates by the Carbon Monitor, an international research initiative begun during the pandemic, show that global carbon dioxide emissions as of the end of September 2021 were just 0.9 percent lower than emissions at the same time in 2019.

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The University of California, Irvine has been named an inaugural Fulbright HSI Leader by the U.S. Department of State’s Bureau of Educational and Cultural Affairs.

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A University of California, Irvine-led study suggests that the glucosyltransferase domain (GTD) is an ideal molecular target for therapeutic interventions for Clostridioides difficile infection (CDI). These findings may lead to new treatments to fight this deadly disease.

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A new study led by University of California, Irvine researchers is the first to reveal the specific molecular mechanism that controls the transition from acute to chronic pain, and identifies this mechanism as a critical target for disease-modifying medicines.

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Lithium is a common medication prescribed to patients with psychiatric disorders, namely bipolar disorder, schizophrenia, and depression. It is used as a mood stabilizer and lessens the intensity of manic episodes, with particular benefit in reducing suicidality. While highly effective, the drug requires routine blood monitoring, which can be uncomfortable, expensive, and inconvenient for patients who must travel to clinical labs for frequent blood testing.

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Lithium is a common medication prescribed to patients with psychiatric disorders, namely bipolar disorder, schizophrenia, and depression. It is used as a mood stabilizer and lessens the intensity of manic episodes, with particular benefit in reducing suicidality. While highly effective, the drug requires routine blood monitoring, which can be uncomfortable, expensive, and inconvenient for patients who must travel to clinical labs for frequent blood testing.

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Lithium is a common medication prescribed to patients with psychiatric disorders, namely bipolar disorder, schizophrenia, and depression. It is used as a mood stabilizer and lessens the intensity of manic episodes, with particular benefit in reducing suicidality. While highly effective, the drug requires routine blood monitoring, which can be uncomfortable, expensive, and inconvenient for patients who must travel to clinical labs for frequent blood testing.

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The 2016 election of former U.S. President Donald Trump was a highly contentious political event fraught with racist and anti-immigrant rhetoric that led to negative changes in mental health across several race/ethnic populations, according to a recent study conducted by University of California, Irvine public health researchers.

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Supply chains problems were in existence for years before the start of Joe Biden's presidency. Prices of containers and pallets, and other myriad corporate choices, have led to the current crisis.

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For the past half century, the University of California, Irvine has been home to some of the world’s leading experts on the environment, energy, oceans and atmosphere in the Golden State. To share their stories, UCI today is launching a web special report, “California’s Climate Crisis.”

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Michael Méndez of the University of California, Irvine has received a two-year, $400,000 grant from the National Center for Atmospheric Research’s Early Career Faculty Innovator Program. It will fund a joint project with researchers at NCAR – which is sponsored by the National Science Foundation – exploring the disparate treatment of undocumented Latino/Latina and Indigenous migrant farmworkers during extreme wildfire events in Sonoma County.

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The University of California, Irvine Program in Public Health has added the Air Pollution Health Effects Laboratory as a research center for the study of airborne environmental and occupational exposures. Originally created in 1973 with funding from the California Air Resources Board to understand the effects of air pollution on human health, over the years the lab has expanded its reach to cover a wide range of environmental exposures.

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In a paper published online in the journal Nature Machine Intelligence, experts from the UK and US are calling for artificial intelligence to be applied to advancing research and developing new therapies to meet the growing global demand for hearing care.

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The University of California, Irvine Program in Public Health has launched the Center for Environmental Health Disparities Research. The center is dedicated to addressing environmental justice through community-based research and promotion of equitable environmental health policies locally and nationally.

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The extract of the plant Corydalis yanhusuo prevents morphine tolerance and dependence while also reversing opiate addiction, according to a recent study led by the University of California, Irvine. The findings were published in the October issue of the journal Pharmaceuticals.

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Psychological therapy reduces the adverse biobehavioral effects of testicular cancer in young adult survivors, according to a pilot study led by the University of California, Irvine. Biobehavior is the interaction of biological processes and behavior. Researchers’ findings, published in the American Journal of Men’s Health, show that Goal-focused Emotion-regulation Therapy, developed specifically to enhance the quality of life for these patients, reduced the stress hormone cortisol and the proinflammatory cell protein cytokine IL-1ra that triggers fatigue, pain and other side effects.

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UCI Program in Public Health, has received $771,000 in research funding from the National Institute of Environmental Health Sciences (NIEHS) to support her new project entitled, “Environmental and Social Health Determinants in Pregnancy Outcomes Related to the COVID-19 Pandemic.”

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Findings from a recent study suggest that saliva could be used for lithium monitoring among patients with mood disorders, potentially replacing methods like blood sampling that are uncomfortable, expensive, and inconvenient for patients.

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Recognizing the widespread use of Twitter as a mainstream news source for the American public, UCI researchers sought to investigate how tweets about masks expressed COVID-19 risk perceptions in the first five months of the pandemic.

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A University of California, Irvine-led study, based on interviews of 50 Latina and Vietnamese women, revealed that this population turns to many sources for information about the HPV vaccine – from online and social media to school health classes, mothers, and doctors.

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The National Institute of Child Health and Human Development has awarded more than $2.5 million to University of California, Irvine researchers seeking to elicit from children more accurate information about maltreatment.

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Glaciologists at the University of California, Irvine and NASA’s Jet Propulsion Laboratory have examined the dynamics underlying the calving of the Delaware-sized iceberg A68 from Antarctica’s Larsen C ice shelf in July 2017, finding the likely cause to be a thinning of ice melange, a slushy concoction of windblown snow, iceberg debris and frozen seawater that normally works to heal rifts.

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The University of California, Irvine today announced a gift from the John Wayne Cancer Foundation that will support advances in research, teaching and service activities in surgical oncology through the creation of an endowed chair and a fellowship in the School of Medicine.

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The University of California, Irvine has received a five-year, $5 million award from the California Institute for Regenerative Medicine to support a comprehensive doctoral, postdoctoral and clinical researcher training program to prepare the current and next generation of leaders in stem cell biology, gene therapy and regenerative medicine.

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Has the scent of freshly baked chocolate chip cookies ever taken you back to afternoons at your grandmother’s house? Has an old song ever brought back memories of a first date? The ability to remember relationships between unrelated items (an odor and a location, a song and an event) is known as associative memory.

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