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30-Jun-1998 12:00 AM EDT
Tiny Molecular Channels Key To Protecting Heart During Attack
Johns Hopkins Medicine

Researchers at Johns Hopkins have come one step closer to understanding the chain of events that protects the heart against injury during a heart attack, paving the way for the development of a new class of drugs to treat people at risk.

Released: 26-Jun-1998 12:00 AM EDT
Pediatric Anesthesiologists Risk Halothane-Related Liver Injury
Johns Hopkins Medicine

Some anesthesiologists may be accidentally inhaling too much of the potent anesthetic gas halothane when they tend to their patients, possibly putting themselves at high risk for liver injury, according to a study by researchers at Johns Hopkins and the National Institutes of Health.

Released: 23-Jun-1998 12:00 AM EDT
Narrow Search For Inflammatory Bowel Disease Genes
Johns Hopkins Medicine

The largest, most comprehensive genome-wide study of patients with inflammatory bowel disease (IBD) -- including Crohn's disease and ulcerative colitis -- has focused and narrowed the search for the genes that cause this common and debilitating illness, a team of researchers from the University of Chicago Medical Center, Johns Hopkins Medical Institutions, and the Marshfield Medical Research Foundation in Marshfield, Wisconsin, report in the June 23 issue of the Proceedings of the National Academy of Scientists.

24-Jun-1998 12:00 AM EDT
Brain Antibodies Provide New Clues to Origins of Tourette's
Johns Hopkins Medicine

Johns Hopkins researchers have found evidence that Tourette's syndrome, which causes involuntary muscle contractions and bursts of words and noise, may be triggered in part by an infection.

Released: 10-Jun-1998 12:00 AM EDT
FDA Approves Hopkins-Designed Implants To Restore Lost Voices
Johns Hopkins Medicine

Johns Hopkins physicians have designed a series of implants that restore bulk to weakened vocal cords, returning the power of speech to those who have lost their voices from paralysis associated with throat cancers, strokes or other conditions. The patented implants were approved by the U.S. Food and Drug Administration in early spring.

Released: 3-Jun-1998 12:00 AM EDT
Vaccine Kills Spreading Cancer In Animal Model
Johns Hopkins Medicine

Johns Hopkins scientists have developed a vaccine that, in mice, can alert the immune system to the presence of stray cancer cells and significantly reduce their blood-borne spread.

31-May-1998 12:00 AM EDT
PSA Levels Mean More Extensive Prostate Disease In Older Men
Johns Hopkins Medicine

In a study of prostate cancer at different ages, Johns Hopkins researchers have found that at diagnosis, older men have more extensive disease than younger men even if their prostate specific antigen (PSA) levels are the same. PSA is a protein made by the prostate; rising blood levels suggest that the prostate is enlarged or even cancerous.

Released: 28-May-1998 12:00 AM EDT
Surgical Removal Seems Best Treatment For Prostate Cancer
Johns Hopkins Medicine

Despite technical refinements in the use of radioactive "seeds" to treat prostate cancer, a study by Johns Hopkins investigators casts doubt on its effectiveness in curing the disease. The radioactive pellets are put into the prostate in a procedure called interstitial radiotherapy.

26-May-1998 12:00 AM EDT
Hopkins Scientists Clock The Speed Of Comprehension
Johns Hopkins Medicine

Capitalizing on an opportunity presented by a patient scheduled for tests using electrodes surgically placed on his brain, Johns Hopkins scientists have clocked the speed of thought, measuring the time the patient took to understand what everyday objects are in pictures.

Released: 21-May-1998 12:00 AM EDT
New Retinal Surgery May Reverse Legal Blindness
Johns Hopkins Medicine

An eye operation that moves the most light-sensitive part of the retina away from an underlying diseased area has saved sight in several people with a common, age-related eye disease.

Released: 21-May-1998 12:00 AM EDT
Cancer Test May Offer High-Risk Groups Quick, Affordable Screening For Tumors
Johns Hopkins Medicine

Johns Hopkins researchers have developed a new test that may allow doctors to regularly and quickly check for early cancers in patients at risk for developing cancer due to genetic or environmental factors.

20-May-1998 12:00 AM EDT
New Test May Reduce Need for Some Prostate Cancer Biopsies
Johns Hopkins Medicine

A new prostate specific antigen (PSA) test that measures the percentage of "free" PSA in the blood not bound to other proteins could spare up to 200,000 men a year in the United States the pain, anxiety and inconvenience of a surgical biopsy to detect cancer.

12-May-1998 12:00 AM EDT
Just One Prenatal Visit Decreases Risk of Preterm Delivery
Johns Hopkins Medicine

Women with a history of premature delivery reduce their risk of another if they seek even a single prenatal checkup, according to results of a Johns Hopkins study.

Released: 12-May-1998 12:00 AM EDT
HIV Discriminates Amongst Cells
Johns Hopkins Medicine

Researchers at Johns Hopkins have discovered that the human immunodeficiency virus (HIV) depends on the moving parts of a cell's surface to allow it to enter the cell.

29-Apr-1998 12:00 AM EDT
Asthma Patients' Histories Can Predict Future Risk
Johns Hopkins Medicine

Johns Hopkins researchers have uncovered a simple way to predict which adult asthma patients are likely to run into asthma problems within the next year and possibly could benefit from different strategies to manage their disease.

Released: 22-Apr-1998 12:00 AM EDT
New AIDS Vaccine Plus Booster Shot Give Best Results
Johns Hopkins Medicine

A vaccine pairing a genetically altered, harmless canarypox virus, and a genetically engineered piece of the HIV protein coat, induce immune system activity against laboratory strains of HIV better than either vaccine alone, according to a Johns Hopkins School of Public Health researcher.

Released: 3-Apr-1998 12:00 AM EST
Johns Hopkins Children's Center Opens New Office to Counter
Johns Hopkins Medicine

Alarmed by the epidemic rate at which children are being exposed to violence - on the streets, in their communities, and through the media - the Johns Hopkins Children's Center has opened an Office for the Prevention of Violence to address the needs of traumatized children and to draw attention to a rapidly escalating public health threat.

1-Apr-1998 12:00 AM EST
Echocardiography Is Effective In Measuring Microvascular Damage From Heart Attacks
Johns Hopkins Medicine

Ultrasound waves may be as effective as magnetic resonance imaging at detecting small blood vessel blockage after a heart attack, according to researchers at Johns Hopkins.

Released: 1-Apr-1998 12:00 AM EST
Molecular Defect Could Be Mysterious Cause of Blood Disorder
Johns Hopkins Medicine

A unique molecular defect in an unusual blood disorder first identified and described at Johns Hopkins by the late Sir William Osler almost a century ago has now been discovered by a team of his professional descendants.

26-Mar-1998 12:00 AM EST
Research Finds That Watching TV Helps Kids Put On Pounds
Johns Hopkins Medicine

Despite living in a society that is increasingly weight and appearance conscious, many American children may be headed toward sedentary, overweight adulthood. Researchers at Johns Hopkins Bayview Medical Center have found that as the hours of television watched by American children increases, so does their weight.

   
21-Mar-1998 12:00 AM EST
Gene-Reading Problem Linked To Lou Gehrig's Disease
Johns Hopkins Medicine

Johns Hopkins researchers have identified genetic mutations that appear to cause or contribute to more than half of all non-inherited or sporadic cases of the deadly muscle disease amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease.

Released: 21-Mar-1998 12:00 AM EST
Vascular Surgeons Test New Treatment For Abdominal Aneurysms
Johns Hopkins Medicine

Vascular surgeons at Johns Hopkins are participating in a nationwide test of a procedure that uses 3-D images and a metal-supported cloth tube to repair stretched and weakened abdominal arteries before they burst and kill.

Released: 17-Mar-1998 12:00 AM EST
Deep Breaths Reduce Wheezing, but only in Non-Asthmatics
Johns Hopkins Medicine

Johns Hopkins researchers have new evidence supporting a controversial theory that asthma is partially caused by the failure of deep breaths to relax constricted lung muscles enough to let in more air.

16-Mar-1998 12:00 AM EST
Allergies To Rubber Affect 12.5 Percent of Health Care Workers
Johns Hopkins Medicine

One in 10 health care workers frequently exposed to rubber surgical and examination gloves is on the cusp of developing allergy symptoms that could seriously affect both their health and their careers, according to a new study from Johns Hopkins Medical Institutions.

Released: 14-Mar-1998 12:00 AM EST
Non-Surgical Treatment Ends Pelvic Pain In Women
Johns Hopkins Medicine

Pelvic congestive syndrome, a painful disorder in women, which often goes undiagnosed and untreated, can usually be cured by plugging blood vessels in the ovaries, according to a study by a Johns Hopkins radiologist.

Released: 7-Mar-1998 12:00 AM EST
Stroke-Preventing Operation Is Safe Even For The Elderly
Johns Hopkins Medicine

A widely used operation to prevent stroke by removing blockages from blood vessels in the neck is safe even for the elderly -- and safest and least expensive when done in hospitals performing the greatest number, a Johns Hopkins study has found.

6-Mar-1998 12:00 AM EST
New Imaging Technique Pinpoints Dead Heart Muscle
Johns Hopkins Medicine

Scientists at Johns Hopkins have developed the first precise, noninvasive means of measuring a chemical in the heart tied to the extent of muscle damage from a heart attack.

3-Mar-1998 12:00 AM EST
Condom Use In Thailand Dramatically Cuts HIV Infection
Johns Hopkins Medicine

A five-year educational campaign to increase condom use in Thailand has led to a fivefold decrease in HIV infection among young army draftees in northern Thailand and a tenfold decrease in sexually transmitted diseases (STDs) overall, according to Johns Hopkins researchers.

3-Mar-1998 12:00 AM EST
MRI Scans Following Heart Attack Could Determine Future Health
Johns Hopkins Medicine

Magnetic resonance imaging (MRI) of the heart after a heart attack may help determine which patients do well and which ones will later suffer complications such as recurrent heart attack, congestive heart failure, stroke or death, according to a study led by Johns Hopkins researchers.

Released: 3-Mar-1998 12:00 AM EST
Researchers Closing In On Gene For Paralytic Disorder
Johns Hopkins Medicine

Scientists at Johns Hopkins and the University of Pennsylvania have tracked down the gene responsible for a paralyzing disease that has plagued at least eight generations of a Maryland family, the Mattinglys.

Released: 28-Feb-1998 12:00 AM EST
New Math, High-Tech Imaging Solving Old Riddle: How Does The Brain Operate When We Think?
Johns Hopkins Medicine

Researchers from Johns Hopkins and Finland are showing that fancy mathematical footwork plus detailed magnetic resonance imaging pictures of the brain may add up to a better understanding of the experience of thinking.

17-Feb-1998 12:00 AM EST
Cancer Cells Self-Destruct When "Sweet Tooth" is Thwarted
Johns Hopkins Medicine

Johns Hopkins researchers have found evidence that some cancer cells are such incredible sugar junkies that they'll self-destruct when deprived of glucose, their biological sweet of choice.

15-Feb-1998 12:00 AM EST
Women Younger Than 30 Need To Be Screened For Chlamydia
Johns Hopkins Medicine

Inexpensive screening of all sexually active young women under 30 for Chlamydia trachomatis infection would vastly reduce infertility and the costly medical complications of this sexually transmitted disease, according to results of a Johns Hopkins study.

Released: 6-Feb-1998 12:00 AM EST
Three-Day Treatment Cures Decades-Old Case of Malaria
Johns Hopkins Medicine

A Johns Hopkins physician has discovered that a 74-year-old woman originally diagnosed with a blood cell cancer actually had a very mild case of malaria that lasted for as many as 70 years. Once he nailed down the cause of her symptoms, he cured her within three days.

Released: 5-Feb-1998 12:00 AM EST
Organ Rejection Drug Also Shows Promise For The Treatment Of Kidney Disease
Johns Hopkins Medicine

A Johns Hopkins evaluation of a drug commonly used to prevent rejection of kidney transplants has found that it also may help patients with severe symptoms of kidney disease.

4-Feb-1998 12:00 AM EST
More Education, More Headaches
Johns Hopkins Medicine

Women get more tension headaches than men and people with advanced degrees suffer more often from tension headaches than the less educated, according to a recent study of tension headache prevalence conducted by researchers at the Johns Hopkins University School of Public Health.

Released: 14-Jan-1998 12:00 AM EST
Hopkins Bayview Researcher Chips Away At Olestra Controversy
Johns Hopkins Medicine

According to research by a Johns Hopkins Bayview Medical Center physician, potato chips made with olestra don't cause any more digestive problems than regular-fat potato chips and, despite containing only half the calories, are just as filling. Olestra, a nonabsorbable fat substitute, has been making news headlines since its approval by the FDA two years ago for use in snack products.

7-Jan-1998 12:00 AM EST
Natural Estrogens May Help Protect Women From Brain Damage During Stroke
Johns Hopkins Medicine

Natural estrogens may offer some protection to premenopausal women threatened with severe brain damage during stroke, according to a study led by researchers at Johns Hopkins and the National Institutes of Health.

Released: 20-Dec-1997 12:00 AM EST
Johns Hopkins Business of Medicine Tips and Briefs
Johns Hopkins Medicine

Johns Hopkins Business of Medicine Tips and Briefs-- Listed are story ideas from the Johns Hopkins Medical Institutions.

Released: 17-Dec-1997 12:00 AM EST
Diabetic Men at 13 Times Higher Risk for End-Stage Renal Disease than Non-Diabetic Men
Johns Hopkins Medicine

Diabetes has long been known to be one major cause of end-stage renal disease (ESRD), but the magnitude of risk has been uncertain. Now, a study led by Johns Hopkins researchers finds that diabetic men are nearly 13 times more likely to develop ESRD than non-diabetic men.

Released: 17-Dec-1997 12:00 AM EST
Expanding AIDS Epidemic In India Includes Monogamous Wives
Johns Hopkins Medicine

AIDS is spreading among young, monogamous, married women in India who get infected by apparently promiscuous husbands, according to a study by researchers at Johns Hopkins and the National AIDS Research Institute in Pune, India.

16-Dec-1997 12:00 AM EST
Strong Response To Mental Stress Could Indicate Heart Disease
Johns Hopkins Medicine

An exaggerated response to mental stress could be a marker for future heart disease among people under age 60 with a strong family history of premature heart disease, according to a study by Johns Hopkins researchers.

Released: 12-Dec-1997 12:00 AM EST
Symptoms Found That Identify Early-Stage HIV Infection
Johns Hopkins Medicine

Researchers from Johns Hopkins and India find that a simple set of symptoms including fever, joint pain, and night sweats can quickly identify people who recently have been infected with the AIDS virus, even before there is evidence from a blood test. Unprotected sex with a prostitute and a fresh genital ulcer also are tip-offs to recent HIV infection.

6-Dec-1997 12:00 AM EST
Hopkins Researchers Closing In On Manic-Depressive Gene
Johns Hopkins Medicine

Johns Hopkins researchers have confirmed that a gene related to bipolar disorder in families is located in the "long arm" of human chromosome 18.

Released: 5-Dec-1997 12:00 AM EST
Knee Replacement Patients Who Have Dental work Susceptible To Infection Years After Surgery
Johns Hopkins Medicine

People who have total knee replacements and later undergo extensive dental work may be susceptible to knee infections years after their initial surgery, according to a study by Johns Hopkins physicians.

18-Nov-1997 12:00 AM EST
Hopkins Researchers Find Drug May Help Cystic Fibrosis Patients
Johns Hopkins Medicine

Researchers at the Johns Hopkins Children's Center have found that a drug used to normalize blood ammonia levels also holds promise for cystic fibrosis.

Released: 15-Nov-1997 12:00 AM EST
Brain Scans Prove Dopamine's Involvement In Cocaine Abuse
Johns Hopkins Medicine

Scientists at Johns Hopkins have used brain scans to show that intravenous doses of cocaine increase the availability of dopamine, the brain's "feel-good" chemical.

14-Nov-1997 12:00 AM EST
Surviving AIDS Appears to Require Permanent Triple-Drug Therapy
Johns Hopkins Medicine

Researchers from Johns Hopkins, the Aaron Diamond AIDS Research Center (New York, N.Y.) and the University of California, San Diego, have shown that drug "cocktail" therapy for AIDS does not completely clear the body of HIV. Rather, small amounts of the virus remain "hidden" in immune system cells, unable to cause disease or develop resistance to anti-AIDS drugs.

11-Nov-1997 12:00 AM EST
Adenovirus May Play A Role In Heart Inflammation
Johns Hopkins Medicine

Adenoviruses, viruses that cause common upper respiratory infections, may also cause life-threatening heart muscle inflammation in adults, according to a study led by Johns Hopkins researchers.

11-Nov-1997 12:00 AM EST
"Mighty Mice" Gene Is Mutated In Beefy Bovines
Johns Hopkins Medicine

The same genetic "secret formula" that gave unusually large muscles to the "mighty mice" engineered by Johns Hopkins is also at work naturally in specially bred cattle that have extra muscle, according to a new report from the researchers.



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