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Researchers have found an enzyme in the blood that could be a marker for heart failure. They previously showed that GRK2 is increased in failing human hearts and contributes to the heart losing contractile strength. Using tissue samples from heart failure patients, they found they could track heart levels of GRK2 in the blood.
Researchers have found a way to create a permanent chemical bond between antibiotics and titanium, which is used in implants. They showed that an antibiotic can be connected to the titanium surface in an active form, and can kill bacteria and prevent infection.
Researchers have identified a gene defect in mice resulting in a range of abnormalities, from hair loss and skin cancer to problems in skin development. The work may lead to improved treatments for skin injuries, including burns, and might have implications for diseases such as eczema and psoriasis, as well as certain cancers.
Richard G. Pestell, M.D., Ph.D., an internationally renowned expert in oncology and endocrinology, has been named director of the Kimmel Cancer Center at Jefferson in Philadelphia. With this appointment, the cancer programs at Jefferson are being restructured and the role of the cancer center director expanded.
Using transparent zebrafish embryos, researchers have shown that a microscopic nanoparticle can help fend off damage to normal tissue from radiation. The nanoparticle, a soccer ball-shaped, hollow, carbon-based structure known as a fullerene, acts like an "oxygen sink," binding to dangerous oxygen radicals produced by radiation.
Researchers have found that mice with low levels of the protein hormone adiponectin may also have high levels of a protein called albumin which, in humans, may be a sign of kidney disease. This study provides further support for the theory that kidney disease may be a more important risk factor for heart disease than is cholesterol.
By coating the surfaces of tiny carbon nanotubes with monoclonal antibodies, biochemists and engineers at Jefferson Medical College and the University of Delaware have teamed up to detect cancer cells in a tiny drop of water.
Glucosamine, the over-the counter natural product that has been touted to help with joint and cartilage problems associated with arthritis, may also provide some relief to individuals with multiple sclerosis (MS).
If heart disease and diabetes aren't bad enough, now comes another reason to watch your weight. A team has shown that being extremely overweight or obese increases the likelihood of developing Alzheimer's.
Age doesn't necessarily have to be the deciding factor for pancreatic cancer surgery. Jefferson Medical College surgeons and colleagues studied records of pancreatic surgery during the last 35 years at a major academic medical center and found that contrary to what many both in and out of medicine may believe, major pancreatic cancer surgery can successfully be performed on patients in their 80s, 90s and even older.
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