NIH supported early testing of the artificial retina. Now, scientists are testing whether manufacturing it on the International Space Station results in a viable treatment for people with blinding eye diseases.
You’ve probably heard that the first two vaccines approved for battling COVID-19 in the United States use a relatively new approach—injections of simple packets containing mRNA, a genetic material that instructs our cells to make coronavirus spike proteins. But the technology for generating sufficient amounts of those mRNA packets dates back to the 1980s, when F. William Studier, then a senior biophysicist at the U.S. Department of Energy’s Brookhaven National Laboratory, developed a way to harness the molecular machinery of a very different virus.
Worldwide, 1 in 4 people will suffer from a depressive episode in their lifetime. While current diagnosis and treatment approaches are largely trial and error, a breakthrough study by Indiana University School of Medicine researchers sheds new light on the biological basis of mood disorders and offers a promising blood test aimed at a precision-medicine approach to treatment.
Brain-computer interfaces (BCIs) are an emerging assistive technology, enabling people with paralysis to type on computer screens or manipulate robotic prostheses just by thinking about moving their own bodies.
Rodeo Therapeutics Corp., a drug-development startup founded by two leading researchers from the Case Western Reserve University School of Medicine and a third scientific partner, has been sold to Amgen Inc., a publicly traded international biopharmaceutical company. Under terms of the agreement, Amgen, based in Thousand Oaks, California, will acquire all outstanding shares of Rodeo for $55 million, plus “future contingent milestone payments potentially worth up to an additional $666 million in cash,” the companies announced today. Total consideration to Rodeo stakeholders could potentially be worth up to $721 million in cash.
Bioengineering researchers at Lehigh University have identified a previously unknown interaction between receptors in human cells and the spike, or "S," protein of SARS-CoV-2, the virus that causes COVID-19.
Scientists at the Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in Japan have revealed molecular mechanisms involved in eliminating unwanted cells in the body.
Picture viral RNA as a single component that you can break into one million pieces. Now imagine reassembling those pieces together, literally like a jigsaw puzzle. If there’s a chipped corner or if a piece won’t fit snugly as it should, consider that a virus mutation or variant. That’s genomic sequencing, in a nutshell, when it comes to identifying variants of COVID-19, according to Peter Stoilov, associate professor of biochemistry at the West Virginia University School of Medicine.
Researchers led by TMDU fabricate a material that will aid bone healing, help medical practitioners clearly assess the full damage to bones after an injury, and clarify probable patient outcomes.
Plastomics will use its proprietary transformation technologies to introduce Amfora gene-editing constructs into high performance soybean germplasm.
Helping to strengthen the economic viability of biorefineries in the production of alternative fuels derived from biomass is critical to decreasing the use of fossil fuels and mitigating carbon dioxide emissions.
Patricia Bernal, a Ramón y Cajal researcher at the Department of Microbiology of the University of Seville's Faculty of Biology, is working with the bacterium Pseudomonas putida, a biological control agent found in the soil and in plant roots and which, as such, has the ability to protect plants from pathogen attacks (organisms that cause diseases) also known as phytopathogens.
A novel form of polymerized estrogen developed at Rensselaer Polytechnic Institute can provide neuroprotection when implanted at the site of a spinal cord injury — preventing further damage. This promising result, found in a preclinical model, was recently published in ACS Chemical Neuroscience, and it lays the groundwork for further advancement of this new biomaterial.
Plastomics, Inc. and Evogene Ltd.’s Ag-Seed division announced a collaboration agreement targeting novel insect control traits for soybean. .
Cornell University researchers have created micron-sized shape memory actuators that enable atomically thin two-dimensional materials to fold themselves into 3D configurations. All they require is a quick jolt of voltage. And once the material is bent, it holds its shape – even after the voltage is removed.
Fast-tracking clinical trials, vaccine delivery, and personal protective equipment through engineering: Live virtual event for March 11, 3PM ET
A gene therapy for chronic pain could offer a safer, non-addictive alternative to opioids. Researchers at the University of California San Diego developed the new therapy, which works by temporarily repressing a gene involved in sensing pain. It increased pain tolerance in mice, lowered their sensitivity to pain and provided months of pain relief without causing numbness.
ASME’s VisualizeMED: Modeling and Simulation in Medicine will take place on April 14-15, 2021. This two-day virtual event is enabling the transformation of modeling and simulation in medicine by bringing together industry experts of technology and masters of technique who are effectively implementing it with the goal to increase the application and adoption on a global scale.
In APL Bioengineering, researchers have developed materials that can interface with an injured spinal cord and provide a scaffolding to facilitate healing. To do this, scaffolding materials need to mimic the natural spinal cord tissue, so they can be readily populated by native cells in the spinal cord, essentially filling in gaps left by injury. The researchers show how the pores improve efficiency of gene therapies administered locally to the injured tissues, which can further promote tissue regeneration.
Being able to make blind people see again sounds like the stuff of miracles or even science fiction. And it has always been one of the biggest challenges for scientists.
The heart cannot regenerate new tissue, because cardiomyocytes, or heart muscle cells, do not divide after birth. However, researchers have now developed a shape memory polymer to grow cardiomyocytes. Raising the material’s temperature turned the polymer’s flat surface into nanowrinkles, which promoted cardiomyocyte alignment. The research is part of the growing field of mechanobiology, which investigates how physical forces between cells and changes in their mechanical properties contribute to development, cell differentiation, physiology, and disease.
Researchers have developed new 4D hydrogels — 3D materials that have the ability to change shape over time in response to stimuli — that can morph multiple times in a preprogrammed or on-demand manner in response to external trigger signals.
Gene editing technology will play a vital role in climate-proofing future crops to protect global food supplies, according to scientists at The University of Queensland.
HSE University researchers have become the first in the world to discover genetic predisposition to severe COVID-19. The results of the study were published in the journal Frontiers in Immunology.
Fool the novel coronavirus once and it can’t cause infection of cells, new research suggests. Scientists have developed protein fragments that bind to the Spike protein, effectively tricking the virus into “shaking hands” with a replica rather than the receptor that lets the virus into a cell.
NASA, in collaboration with other leading space agencies, aims to send its first human missions to Mars in the early 2030s, while companies like SpaceX may do so even earlier.
Researchers have produced a groundbreaking new reference genome for the Asian malaria vector mosquito Anopheles stephensi. The achievement will help scientists engineer advanced forms of defense against malaria transmission, including targeted CRISPR and gene drive-based strategies.
Jonathan Dordick, the Howard P. Isermann ’42 Professor of Chemical and Biological Engineering at Rensselaer Polytechnic Institute, has been elected to the National Academy of Engineering (NAE), for his “contributions to methods for rapidly screening drug efficacy and toxicity, and biocatalytic technologies for improving human health.”
Wearable devices can identify COVID-19 cases earlier than traditional diagnostic methods and can help track and improve management of the disease, according to a Mount Sinai study.
Using patient data, artificial intelligence can make a 90 percent accurate assessment of whether a person will die from COVID-19 or not, according to new research at the University of Copenhagen.
Researchers from Cornell and Northwestern University have devised a new method of using extracts derived from bioengineered bacteria to create vaccines that protect against life-threatening infections caused by pathogenic bacteria.
Some promising biosensors and medical devices work well within pristine laboratory environments but may stop working once exposed to real-world conditions. A thick layer of foulants will quickly cover biosensors, and there is no good way to revive them once they quit working. Essentially, a biosensor is only as good as its antifouling properties. In APL Materials, researchers review a variety of approaches developed to combat fouling.
Our genetic codes control not only which proteins our cells produce, but also - to a great extent - in what quantity.
Thunderbird School of Global Management announces the first of two prestigious Hoffmann Fellowships appointed in collaboration with the World Economic Forum for post-doctoral research and policy innovation at the intersection of society, science and technology.
ORNL story tips: Volcanic microbes, unbreakable bonds and flood mapping
Exemplary faculty and students from Cal State Fullerton, CSUN and Sacramento State were honored during the virtual university-wide symposium.
In research published today in Integrative Biology, a team of engineers from Rensselaer developed an in vitro — in the lab — lymphatic vessel model to study the growth of tumor emboli, collections of tumor cells within vessels that are often associated with increased metastasis and tumor recurrence.
A team of researchers co-led by Berkeley Lab and Columbia University has developed a new material called avalanching nanoparticles that, when used as a microscopic probe, offers a simpler approach to taking high-resolution, real-time snapshots of a cell’s inner workings at the nanoscale.
Researchers at Karolinska Institutet in Sweden have developed, in collaboration with researchers in Germany and the U.S., new small antibodies, also known as nanobodies, which prevent the SARS-CoV-2 coronavirus from entering human cells.
Researchers show that microbes are capable of an incredible feat that could help reclaim a valuable natural resource and soak up toxic pollutants.
Researchers at Carnegie Mellon University report findings on an advanced nanomaterial-based biosensing platform that detects, within seconds, antibodies specific to SARS-CoV-2, the virus responsible for the COVID-19 pandemic.
Carrageenans, biologically active polysaccharides isolated from red algae and widely used in the food industry as stabilizers, thickeners, or jelly agents have an express effect on the immune systems of mice, a study reports.
In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS), discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of some cancer cells, making them resistant to treatment.
Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens.
How can cells adhere to surfaces and move on them?
New research shows the same proteins that enable human senses such as smell also allow certain fungi to sense something they can eat.
GenScript USA Inc., the world’s leading research reagent provider, announced today that Brazil's National Health Surveillance Agency (ANVISA) (Agência Nacional de Vigilância Sanitária) has authorized the use of the cPass™ SARS-CoV-2 Neutralization Antibody Detection Kit for detecting neutralizing antibodies. The cPass test is the first and only ANVISA authorized test for detecting neutralizing antibodies to SARS-CoV-2. Neutralizing antibodies specifically block the ability of a virus to infect a cell and are well-recognized to confer immunity.
Researchers from Berkeley Lab and Los Alamos National Laboratory have developed new methods for the large-scale production, purification, and use of the radioisotope cerium-134, which could serve as a PET imaging radiotracer for a highly targeted cancer treatment known as alpha-particle therapy.
Newly published study reports InvisiMask™, a self-administered single-dose nasal spray, protects against SARS-CoV-2 infection for up to 10 hours in mice
Leaders in stem cell science and regenerative medicine will combine two separate courses into one in June 2021.
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