Centers are enrolling patients in a landmark international trial to determine whether defibrillator devices can save lives when implanted in diabetic patients who have had prior heart attacks.
Each year in the U.S., more than 300,000 people have heart surgery. To reduce risk of stroke for their patients, surgeons often will close the left atrial appendage, which is a small sac in the left side of the heart where many blood clots form, during these surgeries. Mayo Clinic researchers report today in JAMA that adding this procedure is likely the right choice for certain patients but not all.
Patients with prediabetes who also have obstructive sleep apnea (OSA) may improve their resting heart rate, an important measure of cardiovascular health, by using continuous positive airway pressure (CPAP) to treat their OSA, according to a randomized, controlled trial presented at the ATS 2018 International Conference.
Dogs born June through August are at higher risk of heart disease than those born other months, rising in July to 74 percent higher risk, according to a study published this week in Scientific Reports from researchers at the Perelman School of Medicine at the University of Pennsylvania. A correlation to outdoor air pollution may be the culprit.
Researchers at University of California San Diego School of Medicine and their collaborators have developed a technique that allows them to speed up or slow down human heart cells growing in a dish on command — simply by shining a light on them and varying its intensity. The cells are grown on a material called graphene, which converts light into electricity, providing a more realistic environment than standard plastic or glass laboratory dishes.
Researchers from Washington State University have discovered how a genetic mutation linked to hypertrophic cardiomyopathy disrupts the heart’s normal function. The study, which will be published May 18 in the Journal of General Physiology, reveals that the mutation prevents the heart from increasing the amount of force it produces when it needs to pump additional blood around the body.
A new study compared EMS use of endotracheal intubation versus a laryngeal tube for patients with out-of-hospital cardiac arrest. Results indicate increased survival rates with use of the laryngeal tube.
• Among hospitalized adults, those who experienced acute kidney injury were 44% more likely to be hospitalized for heart failure in the year after discharge.
In a landmark study, researchers found that patients treated with paramedic oxygen delivery using a newer, more flexible laryngeal breathing tube may have a greater survival rate after sudden cardiac arrest than the traditional intubation breathing tube.
By analyzing reported physical activity levels over time in more than 11,000 American adults, Johns Hopkins Medicine researchers conclude that increasing physical activity to recommended levels over as few as six years in middle age is associated with a significantly decreased risk of heart failure, a condition that affects an estimated 5 million to 6 million Americans.
A new study reveals that essential fats in the diet may play a role in regulating protein secretion in the muscles by changing the way genes associated with secretion act. The study is published ahead of print in Physiological Genomics.
Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics.
The most common heart medications may get an assist from nitric oxide circulating in the body, according to a new study out of Case Western Reserve University School of Medicine. Researchers showed that nitric oxide may help commonly used heart drugs maximize their benefits while improving heart function. In turn, the study found nitric oxide deficiencies could underlie heart failure while tilting drug effects toward more harmful pathways and side effects.
Atrial fibrillation patients who are diagnosed with carotid artery disease face higher risks for developing dementia, according to new research from the Intermountain Medical Center Heart Institute in Salt Lake City.
UCLA researchers have identified for the first time a receptor in the cell membranes of the heart that plays a key role in repairing damage caused by heart attack and cardiac arrest. The discovery of the receptor, in mouse and rat hearts, explains the mechanisms behind the protective effects of lipid emulsion and could improve treatments for humans with heart disease.
David H. Adams, MD, Cardiac Surgeon-in-Chief and Chair of Cardiovascular Surgery at Mount Sinai Health System, has received the highest "two-star" safety rating from the New York State Department of Health.
Researchers have identified that enlargement of the left atrium of the heart is linked to abnormal activity of molecules that are associated with adverse changes in the heart’s size, shape, structure, and function — conditions that can lead to atrial fibrillation and death.
Doctors know patients with atrial fibrillation are at a higher risk of having a stroke, and now a new study finds that integrating two separate clinical risk score models more accurately helps clinicians assess the stroke risk of patients with Afib.
Chronic inflammatory diseases such as cardiovascular disease, diabetes, obesity, cancer and lupus have their highest U.S. concentrations in the Southeast. Yet, says Fran Lund, the majority of clinical trials to test possible new treatments for these diseases occur outside of the Southeast.
An article in AACN Advanced Critical Care explores how healthcare professionals can use genomic science to identify and counsel patients at risk for inherited disorders that are common causes for sudden cardiac death. The article is part of a symposium in the journal that explores the current state of genomics medicine as it relates to various diseases.
A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.
Michael Kotlikoff, provost of Cornell University and a professor of molecular physiology, is part of an international collaboration that is aiming to prevent heart arrhythmias with a simple gene-therapy approach.
Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.
Scott & White Medical Center – Temple performed its 500th transcatheter aortic valve replacement (TAVR) procedure on a Waco resident, marking a major program milestone.
Over 150 experts from Children’s Hospital of Philadelphia (CHOP) will travel to Toronto for this year’s Pediatric Academic Societies (PAS) Meeting.
Does your child dream of making the team next year at school? While the fall semester is months away, now’s the time to schedule a sports physical, according to experts at The University of Texas Health Science Center at Houston (UTHealth).
Sympathetic nerve activity to skeletal muscle blood vessels—a function of the nervous system that helps regulate blood pressure—increases during physiological and mental stress in people with chronic anxiety, a new study finds.
Hackensack Meridian Health Riverview Medical Center is thrilled to announce the addition of the da Vinci Xi Surgical System, providing its surgeons with unparalleled precision, dexterity and control that allows for a minimally invasive surgical approach for many complex surgical procedures. Already home to the da Vinci Si™, the addition of the da Vinci Xi Surgical System adds to the already robust robotic surgery program at Riverview Medical Center, where surgeons perform a multitude of minimally invasive surgeries for complex diseases and conditions in gynecology, urology, thoracic, cardiac, and general surgery.
After eight years of failed treatment for persistent atrial fibrillation (AF), Janet Szilagyi, 78 of Clayton, New Jersey, became the first patient in the United States to undergo cardiac ablation – a procedure in which an electrophysiologist will scar or destroy tissue in the heart that’s allowing incorrect electrical signals to cause an abnormal heart rhythm – using an intraoperative imaging and mapping system recently cleared by the Food and Drug Administration (FDA).
University of Illinois at Chicago researchers have discovered a way turn pluripotent stem cells into atrial cells. The discovery will enable them to better study atrial fibrillation, the most common heart rhythm disorder.
New research led by investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center suggests that the location of immune cells in the body determines whether they help or harm the development of heart disease. The study supports the view that the immune system directly impacts heart failure—still the leading cause of death for men and women in the United States.
A presentation at the 2018 American Association of Neurological Surgeons Annual Scientific Meeting
The addition of a nurse-led intervention for hypertension management to health insurance coverage was more effective in lowering blood pressure (HPB) than the provision of health insurance alone in the Sub-Saharan country of Ghana, a region of Africa where HPB is rampant, according to a study publishing online on May 1 in the journal PLOS Medicine.
UCLA geneticists have created a technique to hunt for hormones that influence how organs and tissues communicate with each other. The method enabled them to find naturally occurring molecules that play major roles in Type 2 diabetes, obesity and cardiovascular disease.
Medicare and Medicaid beneficiaries with end-stage heart failure seeking OHT and LVAD implantation will be drastically affected if the proposed cuts are implemented, according to UAB research.
UT Southwestern cardiologist Dr. Ambarish Pandey has been named a Texas Health Resources Clinical Scholar. Funding from this award will bolster his studies developing novel approaches to prevent heart failure and improve heart failure outcomes at a health system level.
Tip sheet
Mandatory public reporting of coronary artery bypass grafting (CABG) results in Massachusetts was associated with better patient outcomes compared to national findings, according to a recent study. Results of the 13-year Massachusetts experience were presented in a plenary session of the American Association for Thoracic Surgery’s 98th Annual Meeting.
PHILADELPHIA – Susan Brozena, MD, FACC, FAHA, an emeritus associate professor of Cardiovascular Medicine in the Perelman School of Medicine at the University of Pennsylvania, received the 2018 Lifetime Achievement Award from the American Heart Association. This award celebrates a professional who has had a pioneering career and has made an exceptional impact on their patients, the Philadelphia community and the field of cardiology.
You’ve heard of “nature versus nurture,” and philosophers argue about which is more important. But how does this work on the cellular level?
Drinking kefir may have a positive effect on blood pressure by promoting communication between the gut and brain. Kefir is a fermented probiotic milk beverage known to help maintain the balance of beneficial bacteria in the digestive system. Researchers will present their findings today at the American Physiological Society (APS) annual meeting at Experimental Biology 2018 in San Diego.
Researchers investigating a key signaling protein in Huntington’s disease describe deleterious effects on heart function, going beyond the disease’s devastating neurological impact. By adjusting protein levels affecting an important biological pathway, the researchers improved heart function in mice, shedding light on the biology of this fatal disease.
A genomic analysis of a large study population has identified uncommon gene variants involved in responses to dietary fats and medicine. Although these variants are rare, they may play a large role in a carrier's risk of heart disease.
According to new research, obese women with polycystic ovary syndrome (PCOS) may be able to improve their health outlook with a particularly enjoyable form of therapy: regular sessions in a hot tub.
A major issue that limits modeling to predict cardiac arrhythmia is that it is impossible to measure and monitor all the variables that make our hearts tick, but researchers have now developed an algorithm that uses artificial intelligence to model the electrical excitations in heart muscle. Their work, appearing in Chaos, draws on partial differential equations describing excitable media and echo state networks to cross-predict variables about chaotic electrical wave propagations in cardiac tissue.
People who are 30 pounds or more overweight may want to slim down a bit even if they don’t have high blood pressure or any other heart disease risk, according to scientists at Wake Forest Baptist Medical Center.
Physicians from Cedars-Sinai and Stanford Children’s Health are teaming up to offer the newest treatments and surgical techniques to patients born with heart defects. The new collaboration between the two prominent institutions features doctors from the Smidt Heart Institute’s Guerin Family Congenital Heart Program at Cedars-Sinai and the Betty Irene Moore Children’s Heart Center at Lucile Packard Children’s Hospital Stanford. Both teams focus on treating patients born with heart defects who require specialized care throughout their lives.
When compared with nondrinkers, men and women who had one or more alcoholic drinks per day had an overabundance of oral bacteria linked to gum disease, some cancers, and heart disease. By contrast, drinkers had fewer bacteria known to check the growth of other, harmful germs.
The bacteria that reside on and within our bodies are known to have a significant influence on our health. New research suggests wiping out the gut microbiota could improve heart functioning and potentially slow the cardiac damage that occurs with heart failure.
A team led by Columbia University Biomedical Engineering Professor Gordana Vunjak-Novakovic has designed a creative new approach to help injured hearts regenerate by applying extracellular vesicles secreted by cardiomyocytes rather than implanting the cells. The study shows that the cardiomyocytes derived from human pluripotent stem cells (derived in turn from a small sample of blood) could be a powerful, untapped source of therapeutic microvesicles that could lead to safe and effective treatments of damaged hearts.
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