Stroke survivors with higher scores on widely used outcome measures are more likely to be discharged home from the hospital, while those with lower scores are more likely to go to a rehabilitation or nursing care facility, reports a paper in the January issue of The Journal of Neurologic Physical Therapy (JNPT). The journal is published by Wolters Kluwer.
Wolters Kluwer Heath, in partnership with the Education Section of the American Physical Therapy Association (APTA), will begin publishing the Journal of Physical Therapy Education (JOPTE) with online publication of the December 2017 issue. JOPTE is the eighth APTA journal added to the Lippincott portfolio.
Penn Medicine’s Innovation Accelerator Program, now in its fifth year, has announced funding for four new projects aimed at addressing disparities to improve health care delivery and patient outcomes.
Canola oil is one of the most widely consumed vegetable oils in the world, yet surprisingly little is known about its effects on health.
Cancer care in South Jersey is about to enter a new era. Penn Medicine, in partnership with Virtua, announced plans to build a new proton facility on the campus of Virtua’s acute care hospital, Virtua Voorhees. The new $35 million center, which will allow cancer patients to undergo cutting edge proton therapy in single-room treatments, is expected to be completed by 2020. It will be the first and only proton therapy center in South Jersey.
Douglas H. Smith, MD, the Robert A. Groff Professor of Neurosurgery at the Perelman School of Medicine at the University of Pennsylvania, has received a $4-million, four-year PACT (PA Consortium on Traumatic Brain Injury) award from the Pennsylvania Department of Health to lead a multi-institution effort to transform the prevention, diagnosis, and treatment of traumatic brain injury.
An international panel of experts has created a roadmap to help identify which men and their families may benefit from genetic evaluation for inherited prostate cancer.
Research from the Monell Center documented wide individual differences to the taste of the life-saving HIV medication Kaletra and identified genetic sources of the taste variation. The findings suggest that the growing field of pharmacogenetics should assess the sensory response to medicines to promote medication compliance and treatment success.
Someone who binge eats consumes an objectively large amount of food while feeling a loss of control over eating. When episodes occur weekly for several months, the action moves into the realm of binge-eating disorder. So how does this type of eating affect people with Type 2 diabetes and obesity who are actively working to lose weight?
A pilot study collected physiological information from six healthy young male volunteers as they went about their normal daily lives. Thousands of indicators were measured with wearable devices and smart phone apps. The study showed the feasibility to detect the chronobiome of an individual -- a collection of physiological traits in a 24-hour rhythmic pattern -- despite the ‘noise’ of everyday life.
Some complications are more common when total knee replacement surgery is done as an outpatient or same-day procedure, reports a study in the December 6, 2017 issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.
The international admissions director was saluted by The Chronicle of Higher Education for her role in the #YouAreWelcomeHere campaign.
Despite the fact that their disease may be more severe, a new study shows minorities are less likely than white Americans to see a doctor for psoriasis treatment. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that black, Asian, and other non-Hispanic minorities are about 40 percent less likely to see a dermatologist for psoriasis than whites.
Pets have become an integral part of human medical research. However, a recent collaboration between Penn Med and Penn Vet has turned the tables on the arrangement.
Employees with laboratory-confirmed influenza have more lost work time—including absences and reduced productivity while at work—compared to those with other types of acute respiratory illness (ARI), reports a study in the December Journal of Occupational and Environmental Medicine.
Two investigational immunotherapy approaches, including chimeric antigen receptor (CAR) T cell therapy, have shown encouraging results in the treatment of multiple myeloma patients who had relapsed and were resistant to other therapies. Researchers from the University of Pennsylvania’s Abramson Cancer Center administered CAR T cells to patients following chemotherapy, with 64 percent of patients responding in a clinical trial. In a separate study, patients got an infusion of an experimental monoclonal antibody, which resulted in an overall response rate of 60 percent. Both of these investigational approaches targeted a receptor called B-Cell Maturation Antigen (BCMA), which is highly expressed in myeloma and thus a promising target for treatment.
Patients with certain advanced hereditary breast cancers may have new treatments options on the horizon, according to two studies presented this week at the annual San Antonio Breast Cancer Symposium. Susan Domchek, MD, executive director of the Basser Center for BRCA at Penn’s Abramson Cancer Center, will present new results from the Mediola and OlympiAD trials showing continued success of treating BRCA-related metastatic breast cancer with the PARP inhibitor olaparib with limited side effects for patients.
Although digital breast tomosynthesis (DBT), or 3-D mammography, costs more than a digital mammography (DM) screening, it actually may help rein in cancer screening costs, according to preliminary findings (PD7-05) presented by researchers from the Perelman School of Medicine at the University of Pennsylvania during the 2017 San Antonio Breast Cancer Symposium.
A schizophrenia patient’s own perceptions of their experiences -- and confidence in their judgments -- may be factors that can help them overcome challenges to get the life they wish, suggests a new paper published in Clinical Psychological Science from researchers at Penn Medicine’s Aaron T. Beck Psychopathology Research Center.
As a part-time librarian while at Swarthmore, David Peele ’50 saw volumes of dusty old books — and mischievous opportunity.
A team of gene therapy researchers has reported positive results in a phase 1/2 clinical trial for the inherited bleeding disorder hemophilia B. A single intravenous infusion of a novel bioengineered gene therapy treatment enabled adult participants to safely produce sustained levels of clotting factor that prevented debilitating bleeding episodes. Patients were able to terminate prophylactic treatments--the gene therapy nearly universally eliminated their need for intravenous infusions of manufactured clotting factor.
The 2017 Klein graduate who grew up only blocks from Main Campus makes history as Temple's first recipient of the prestigious scholarship
DNA sequences between mitochondria within a single cell are vastly different, found researchers. This knowledge will help to better illuminate the underlying mechanisms of many disorders that start with accumulated mutations in individual mitochondria and provide clues about how patients might respond to specific therapies.
New research shows how losing a ubiquitous gene opens genetic floodgates that make prostate cancer deadly, a finding that could apply to many cancers.
The first child to undergo a successful hand transplant also is the first child in whom scientists have detected massive changes in how sensations from the hands are represented in the brain. The brain reorganization is thought to have begun six years before the transplant, when the child had both hands amputated because of a severe infection during infancy. Notably, after he received transplanted hands, the patient’s brain reverted toward a more typical pattern.
Louis J. Soslowsky, PhD, the Fairhill Professor of Orthopaedic Surgery in the Perelman School of Medicine at the University of Pennsylvania, will receive the H.R. Lissner Medal from the American Society of Mechanical Engineers (ASME).
Incidental durotomy—small tears of the outer membrane of the spinal cord—are a common occurrence in spinal surgery, and may lead to litigation. Most malpractice cases associated with dural tear end in a ruling in favor of the surgeon, reports a study in the journal Spine, published by Wolters Kluwer.
Making an AD mouse model that incorporates both Aβ and tau pathologies in a more AD-relevant context has been greatly sought after but difficult to accomplish. This study is a big step for AD research, which will allow testing of new therapies in a more realistic context.
Penn Medicine launches first-of-its-kind app for bariatric surgery patients. Penn Life Gained is built using Apple CareKit, a software framework designed to help people actively manage their own medical conditions.
At this year’s 42nd annual NIAF Gala Weekend at the Washington Marriott Wardman Park Hotel in D.C., all aspects of Italian heritage were celebrated, including food, the fine arts, and scientific discovery. The weekend’s events included the medical conference, “Mediterranean Diet, Human Health and Longevity,” sharing the latest in research into a vital part of Italian culture –– diet and food. Conference presentations explored how the recipes of Italian grandmothers are among the healthiest in the world and can even help fight disease, such as cancer.
Female Parkinson’s disease patients are much less likely than male patients to have caregivers, despite the fact that caregivers report greater strain in caring for male patients. The findings come from a large study reported today in Neurology by researchers at the Perelman School of Medicine at the University of Pennsylvania. According to the researchers, the disparity between female and male patients probably derives in part from the fact that women tend to outlive their most likely potential caregivers: their husbands.
Less than one-third of patients with glaucoma talk to their doctor about the costs of medications needed to control their disease, reports a study in the December issue of Optometry and Vision Science, the official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.
Cancer survivors and patient advocates joined clinicians, employers, policy makers, and pharmaceutical and biotech industry representatives to address survivorship in cancer care at NCCN Patient Advocacy Summit.
An antibody therapy against a key inflammatory molecule involved in migraines reduces the number of headaches that chronic migraine patients experience per month in a phase III trial.
Brand new NCCN Guidelines® map out best practices for treating patients with AIDS-related Kaposi sarcoma.
Physician-researchers from the Cardiac Center at Children’s Hospital of Philadelphia recently presented new findings on pediatric cardiovascular disease at the American Heart Association’s Scientific Sessions 2017 in Anaheim, Calif. Among many abstracts presented were research on racial disparities in bystander CPR methods in children with sudden cardiac arrest, and findings that children with hypertrophic cardiomyopathy may be at risk for sudden cardiac death.
The number of doctors and advance practitioners in the United States who focus on nursing home care rose by more than a third between 2012 and 2015, according to a new study published today in JAMA from researchers at the Perelman School of Medicine at the University of Pennsylvania. Of all physicians and advance practitioners who do any work in nursing homes, 21 percent now specialize in nursing home care. The authors say the trend suggests the rise of a significant new specialty in medical practice, though how it will affect patient outcomes and continuity of care is yet to be seen.
Researchers identify several lncRNAs that are linked to the ovarian cancer in a cohort of patients. These lncRNAs were reproducibly altered and are responsible for a shift in cellular function that contributes to the metastatic properties of the cancer cells.
Among women with dense breast tissue, for whom traditional mammograms are less effective at detecting cancer, who request additional screening after a negative mammogram, abbreviated breast MRI (AB-MR) may be a valuable cancer detection tool. In a study of 195 asymptomatic women with dense breast tissue who had a negative mammogram within the previous 11 months, AB-MR detected five additional cancers after a negative screening mammography, according to preliminary findings from a Penn Medicine team presented this week at the Radiological Society of North America meeting in Chicago.
The traits we inherit from our family define and connect us in countless ways. Sometimes these traits are obvious, like curly hair or dimples. But sometimes what we inherit remains hidden, like BRCA gene mutations. With the help of celebrities like actress Cobie Smulders, star of television comedy series How I Met Your Mother and in the Marvel Cinematic Universe, the Basser Center for BRCA launched a video and social media campaign—with the hashtag #invisiblegenes—in the hopes that it will highlight illnesses that can be prevented or treated with early detection.
People whose genetic makeup triggers a later-than-average start to puberty have lower bone mineral density, especially in their lower spine. Because adolescence is a critical period for accruing bone, this effect may increase a person’s risk of osteoporosis and bone fractures later in life.
Women have smaller, more breakable nerve fibers in the brain compared to men that may make them more susceptible to concussions, suggests a new study from Penn Medicine neuroscientists published online today in the journal Experimental Neurology.
The CORE Prize for Oncology 2017 was awarded to Professor Antonio Giordano for his groundbreaking discoveries in the field of the cell cycle, which have established an understanding of the fundamental mechanisms at the basis of cancer and the development of a new class of anticancer therapeutics.
New study in JNCCN calls for more planning and research to prepare for the increasing financial burden of treating breast cancer.
Can acupuncture and yoga help to fight the opioid epidemic? These and other integrative medicine approaches have shown at least preliminary evidence of effectiveness in pain management, according to an article in the December issue of Anesthesia & Analgesia—a special thematic issue addressing the opioid crisis.
Infants with various forms of congenital heart disease require a stable source of blood flow to their lungs in order to survive until a more definitive operation can be performed. In a recent study, pediatric researchers compared two methods to provide that flow: a shunt to reroute blood and an implanted stent to maintain an open path for blood flow. They found that stents were preferable for selected patients.
Malaria parasites, although widespread among wild chimpanzees and gorillas, have not been detected in bonobos, a chimp cousin. Although the researchers saw evidence of a new malaria species in bonobos, it was limited to one small area of their range. This work helps the hunt for biological loopholes to potentially exploit the life history of ape pathogens to better understand how they cross over to humans.
NCCN and Pfizer announce funding for projects evaluating different clinical care pathways to improve breast cancer care, with a particular emphasis on underserved patients.
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