High doses of acetaminophen can damage the liver. Researchers have found a new mechanism by which an acetaminophen breakdown product can impair liver proteins. The compound activates a protein modification pathway called glutathionylation. The finding explains how the compound can damage even proteins it doesn't bind to directly.
According to a Rutgers study, programs designed to provide social support may impact hospitalization rates and decrease spending. Expert says that investing in affordable housing that offers supportive social services to senior citizens on Medicare has the potential to reduce hospital admissions and the amount of time needing inpatient hospital care by better managing chronic health conditions.
Two studies into deadly cancers in dogs are now underway, offered through the newly formed Clinical Trials Office at Cummings Veterinary Medical Center at Tufts University. Dogs with spontaneous osteosarcoma, as well as dogs with mast cell tumors and solid tumors, may be eligible for enrollment.
The George Washington University and the U.S. Food and Drug Administration published an update to the BioCompute Object Specification Project, which provides much-needed standards for communicating high-throughput sequencing computations and data analysis, known as BioCompute Objects.
A UNC School of Medicine study shows that two cystic fibrosis (CF) drugs aimed at correcting the defected CFTR protein seem to be more effective when a patient’s airway is inflamed. This is the first study to evaluate the efficacy of these drugs under inflammatory conditions relevant to CF airways.
Drug-releasing textiles could, for instance, be used to treat skin wounds. Empa researchers are currently developing polymer fibers that can be equipped with drugs. The smart fibers recognize the need for therapy all by themselves and dose the active ingredients with precision and accuracy.
Ulrich Wiesner, the Spencer T. Olin Professor of Engineering in materials science and engineering at Cornell University, in collaboration with Dr. Michelle Bradbury of Memorial Sloan Kettering Cancer Center (MSKCC) and Weill Cornell Medicine, has proposed a novel approach to antibody-based imaging of cancer using ultrasmall silica nanoparticles – better known as “Cornell dots” (or C dots) – invented in his lab more than a dozen years ago.
SAN FRANCISCO – The American Society of Anesthesiologists (ASA) today announced the recipients of its Perioperative Surgical Home (PSH) Scholarship in which awardees will receive funding to participate in the PSH Learning Collaborative 2020 to support the implementation of a PSH pilot at their institution. The three scholars will be formally awarded, and industry supporters recognized for their support, at a special event on Oct. 15 during the ANESTHESIOLOGY® 2018 annual meeting in San Francisco.
The PhRMA Foundation and the Personalized Medicine Coalition (PMC) have announced the recipients of the 2018 Value Assessment Challenge Awards – designed to encourage innovative approaches in defining and measuring value in health care.
ASHP CEO Paul W. Abramowitz, Pharm.D., Sc.D. (Hon.), FASHP, today attended a White House ceremony to commemorate the signing of S. 2553 and S. 2554, the “Know the Lowest Price Act” and “Patient Right to Know Drug Prices Act,” respectively. ASHP, independently and as a lead member of the Steering Committee of the Campaign for Sustainable Rx Pricing, has long advocated for measures that would improve transparency in drug pricing.
UW engineers developed a new machine-learning system that can help anesthesiologists predict the likelihood that a patient will experience low blood oxygen levels during surgery. This condition, called hypoxemia, can lead to serious consequences, such as infections and abnormal heart behavior. The team’s system also gives real-world explanations behind its predictions. The researchers estimate that it could improve the ability of anesthesiologists to prevent 2.4 million more hypoxemia cases in the United States every year.
New approach provides more accurate analysis of complex genetic and drug/environment data by monitoring over time
The Saint Louis University School of Medicine no longer is on probation after successfully addressing all concerns raised by the Liaison Committee for Medical Education (LCME), the accrediting body for North American medical schools.
Two summers ago, biomedical engineering students at Rutgers University–New Brunswick immersed themselves at Matheny in Peapack, New Jersey, a nonprofit organization that is home to scores of children and adults with cerebral palsy, spina bifida and other developmental disabilities. The students’ goal: find ways to improve their independence and quality of life. After talking with staffers and students at Matheny, the Rutgers students designed prototypes that were demonstrated there last spring. The reaction was very positive.
Elizabeth Engler-Chiurazzi, a research assistant professor in WVU’s School of Medicine, and her colleagues at WVU are among the first researchers to make the connection between B cells and the effectiveness of antidepressants.
Doctors, nurses and clinical staff will lead efforts to transform the electronic health records at Penn Medicine, recognizing them as a tool just as important as scalpels to modern health care delivery.
The American College of Radiology’s Commission on Patient- and Family-Centered Care (CPFCC) announced the formation recently of a new Population Health Management (PHM) Committee. Syed F. Zaidi, MD, is the chair of the new committee. McKinley Glover, MD, will serve as vice chair.
West Virginia University’s School of Pharmacy will soon become one of the few pharmacy schools in the nation that leads a center of biomedical research excellence.
Allen Kachalia, M.D., J.D., will become the senior vice president of patient safety and quality for Johns Hopkins Medicine and director of the Armstrong Institute for Patient Safety and Quality, effective Dec. 1.
Washington University School of Medicine in St. Louis led a national study of 2,400 first-time pregnant women. The research showed that the timing of pushing has no effect on whether women deliver vaginally or by C-section.
Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually develop drug resistance, leaving doctors desperate for alternatives. Now, researchers from Case Western Reserve University School of Medicine have uncovered a previously uncharacterized, bridge-like structure within the human estrogen receptor that could serve as a valuable new drug target. In Nature Communications, researchers describe a “burning the bridge” strategy to disrupting the estrogen receptor, and how to screen breast cancer drugs designed to do it.
TRIUMF, Canada’s particle accelerator centre, is pleased to launch its new Five-Year Plan 2020-2025, developed with extensive internal and external community consultation. It leverages past investments by government and builds on the laboratory’s strong brand and global network to deliver a new level of top-tier science, training, and innovation to Canada for decades to come.
The National Institutes of Health (NIH) has selected the Johns Hopkins University School of Medicine, Baylor College of Medicine and The University of Texas Health Science Center at Houston to lead one of three “genome centers” for its All of Us Research Program.
Rutgers researchers have discovered a new system to deliver antimicrobial agents -- drugs, antiseptics or pesticides -- that could more effectively treat or prevent bacterial infections.
The Maryland Proton Treatment Center (MPTC) is now offering deep-tissue external thermal therapy in combination with high-precision proton-beam radiotherapy as a potential way to boost survival chances for certain cancer patients. MPTC is the only center in the world to offer these two treatments at the same facility, an advantage to patients because these therapies are typically given within an hour of each other.
Currently, a once-daily pill to prevent HIV infection is available. However, adherence to a once-daily regimen can be difficult for some people. Researchers from the UNC School of Medicine and the Centers for Disease Control and Prevention published a study today in Nature Communications that reports a potentially promising remedy for this problem.
For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth.
Peripheral nerve injuries leave people with tingling, numbness and weakness in their arms, hands and legs. Researchers at Washington University School of Medicine in St. Louis and Northwestern have developed an implantable, bioabsorbable device that speeds recovery in rats by stimulating injured nerves with electricity.
A team of nurses and physicians has received a four-year, $3 million grant from the National Heart, Lung, and Blood Institute to extend traditional HIV treatment protocols to improve the cardiovascular health of people living with HIV.
A side effect of opioid use is an infection of the heart valves called drug-associated infective endocarditis. Researchers at the University of North Carolina at Chapel Hill have found a tenfold increase in the number of hospitalizations and surgeries for endocarditis in the past decade.
The American Society of Anesthesiologists (ASA) will host the Run For The Warriors® 5K Run/Walk at 7 a.m. on Sunday, October 14, at Mission Creek Park in San Francisco. The race coincides with the ANESTHESIOLOGY® 2018 annual meeting and marks ASA’s ninth consecutive year of sponsorship.
AMSSM is pleased to announce the Sports Medicine Licensure Clarity Act was signed into law Friday, Oct. 5, by President Donald Trump. The bill represents a bipartisan solution that protects team physicians, athletic trainers and other sports medicine professionals when they travel across state lines with their teams to treat the athletes under their care.
Loyola University Medical Center, which treats some of the Chicago area's most critically ill and injured patients, is establishing a residency program to train new doctors in emergency medicine.
New research from the Keck School of Medicine of USC finds that an online care delivery model is equivalent to in-person care for improving psoriasis symptoms.
Public and private health insurance policies in the U.S. are missing important opportunities to encourage the use of physical therapy, psychological counseling and other non-drug alternatives to opioid medication for treating lower back pain, a study led by researchers at Johns Hopkins Bloomberg School of Public Health has found.
President Donald Trump has touted his new United States-Mexico-Canada Agreement (USMCA) as a way to boost the American economy. It may not, however, have any impact on one of his other campaign promises: reducing prescription costs for U.S. consumers, says a drug pricing expert at Washington University in St. Louis.Buried in the draft of the new pact is a provision that would give pharmaceutical companies a minimum of 10 years to exclusively market biologic drugs, a set of complex medications made from living cells.
A Rutgers University–New Brunswick-led team of researchers is calling for the creation of a global microbiota vault to protect the long-term health of humanity. Such a Noah’s Ark of beneficial germs would be gathered from human populations whose microbiomes are uncompromised by antibiotics, processed diets and other ill effects of modern society, which have contributed to a massive loss of microbial diversity and an accompanying rise in health problems. The human microbiome includes the trillions of microscopic organisms that live in and on our bodies, contributing to our health in a myriad of ways.
A new study found that women who reported taking a low-dose aspirin every day had a 23 percent lower risk of ovarian cancer compared to nonaspirin users. The research also found that women who were heavy users of nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil) or naproxen (Aleve), over a long period of time had a higher risk of developing ovarian cancer.
A twist on the molecular mechanism of how a new cancer drug works could aid in better identifying the best treatments for patients for an array of cancers. The team identified over 500 sites in DNA that require an enzyme called ATR checkpoint kinase to not break when they are replicated.
The University of Texas MD Anderson Cancer Center and Cyclacel Pharmaceuticals, Inc., today announced a three-year strategic alliance agreement that will enable clinical evaluation for safety and efficacy of three Cyclacel medicines in patients with hematological malignancies, including chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and other advanced leukemias.
Penn Medicine experts in nephrology and health policy call for more transparency about joint-venture ownership of dialysis clinics to better understand what impact these arrangements may have on patient referrals and clinical outcomes. The lack of transparency poses a major barrier for evidence-based health care policy research and deprives patients of critical information, the researchers write in a new Perspective published in the New England Journal of Medicine.
AACC, a global scientific and medical professional organization dedicated to better health through laboratory medicine, is pleased to announce that David G. Grenache, PhD, DABCC, MT(ASCP), FAACC, has been elected to serve on the AACC Board of Directors as president-elect starting in January 2019. Following this, he will serve successive terms as the association’s president from August 2020-July 2021 and as past president from August 2021-July 2022. In addition, the AACC membership elected a new treasurer and two new directors to the association’s Board. They will take office at the start of 2019 along with the incoming president of AACC Academy, who will also serve on the Board.
The esports industry is growing quickly and The Ohio State University is leading in its development by forming the most comprehensive esports program to date.
he Sorenson Impact Center’s University Venture Fund - Impact Investing (UVF II) closed its first investment in a seed round into Salt Lake City-based Navigen, Inc.
The annual American College of Emergency Physicians (ACEP) Scientific Assembly will bring together more than 8,000 emergency medicine physicians, including those from Johns Hopkins Medicine. Johns Hopkins Medicine’s Department of Emergency Medicine faculty will present research findings on a variety of topics.
Physicians at the John Theurer Cancer Center at Hackensack Meridian Health Hackensack University Medical Center have enrolled the first two patients nationwide in an international phase II clinical trial of Kazia Therapeutics’s novel therapy, GDC-0084, for glioblastoma.
Peter Wiklund, MD, PhD, a world-renowned surgeon who pioneered robot-assisted cystectomy, has been appointed Director of the Bladder Cancer Program at the Mount Sinai Health System and Professor of Urology in the Department of Urology at the Icahn School of Medicine at Mount Sinai.
University of Minnesota researchers have found a natural product, called Fisetin, reduces the level of damaged cells in the body, which can slow the aging process.
University of California, Irvine Neuroscientist Medha Pathak, PhD, an assistant professor of Physiology and Biophysics at the UCI School of Medicine, and member of the Sue and Bill Gross Stem Cell Research Center and the Center for Complex Biological Systems at UCI, was awarded a prestigious National Institutes of Health Director’s New Innovator Award from the NIH Common Fund’s High-Risk, High-Reward Research program.
Splitting up and getting back together is always hard to do, but for proteins, it's almost impossible. However, a computer-guided algorithm may help scientists find just the right spot to split a protein and then reassemble it to functionality.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right