Feature Channels: Pharmaceuticals

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A clinical trial evaluating the role of statins in the risk of recurrent intracerebral hemorrhage (ICH) in patients presenting with ICH, has opened for enrollment at UTHealth Houston.

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The American Society for Pharmacology and Experimental Therapeutics (ASPET) has automated its Automated Patient-Oriented Problem-Solving (A-POPS) learning tool.

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AASLD, ACG, AGA, ASGE and NASPGHAN recognize that the new class of GLP-1 receptor agonist may be associated with delayed gastric emptying and encourage our anesthesiology, endocrinology, and industry partners to work collaboratively with our members to develop the necessary evidence to appropriately inform medication adjustments prior to elective endoscopy.

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Over 50 million K-12 students across the United States will return to classrooms this month, according to the National Center for Education Statistics. Michigan State University experts provide guidance on how to ensure students are physically and mentally prepared for the new school year.

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A collaborative study undertaken by the Navarrabiomed Biomedical Research Center (Pamplona, Navarre), the Institute of Neurosciences CSIC-UMH (Sant Joan d’Alacant, Valencian Community) and IRB Barcelona (Barcelona, Catalonia) shows that the administration of ranolazine, a drug currently used to treat heart conditions, improves the efficacy of current therapies for melanoma, in mouse models of this disease.

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A new study of mice and lab-grown human colon “organoids” indicates that an experimental drug developed by Johns Hopkins Medicine researchers can substantially reduce symptoms of inflammatory bowel disease (IBD) in pre-clinical models.

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People who take acid reflux medications called proton pump inhibitors for four-and-a-half years or more may have a higher risk of dementia compared to people who do not take these medications, according to new research published in the August 9, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. This study does not prove that acid reflux drugs cause dementia; it only shows an association.

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In a recent study, Illinois Sustainable Technology Center environmental chemist Wei Zheng and colleagues investigated the adsorption of sitagliptin in soils treated with sewage wastewater.

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New and rapidly developing technologies, such as cryo-electron (cryo-EM) and artificial intelligence, are providing the tools to revolutionize biomedical research, but you need scientists who know how to use them

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For the first time in Thailand, lecturers at Chulalongkorn University’s Faculty of Pharmaceutical Sciences have successfully developed antibody from tobacco plants with inhibitory effects on the growth of cancer cells in laboratory animals. This signals hope for access to effective cancer medication and treatment at a lower cost.

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A new study led by Lorraine Kelley-Quon, MD, MSHS, pediatric surgeons at Children’s Hospital Los Angeles shows that methadone use in babies after surgery can lead to longer hospital stays.

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An antibody in single-chain fragment variable (scFv) format that binds to the powerful opioid carfentanil was shown to reverse signs of carfentanil overdose in preclinical tests conducted by scientists at Scripps Research.

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JNCCN study sheds light on a rapid shift in practice evolution by oncologists treating people with colon cancer adjuvantly after primary surgery, following publications from the IDEA collaboration.

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Research from Saint Louis University School of Medicine finds that among patients 65 and older, a diagnosis of anxiety was significantly associated with an increased risk of dementia diagnosis, and benzodiazepine exposure was associated with a 28% increased risk of dementia.

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The key to understanding proteins — such as those that govern cancer, COVID-19, and other diseases — is quite simple. Identify their chemical structure and find which other proteins can bind to them. But there’s a catch.

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Dr. Santiago Mazuera, head of Sinai Hospital's Headache Clinic, shares how Botox treatments can drastically improve quality of life for those who experience chronic migraines.

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A recent study reveals that Metformin, a common drug used to manage Type 2 Diabetes, could offer new hope for treating periodontitis, a chronic inflammatory disease affecting oral tissues. The study explored the effects of Metformin on HMGB1 (High Mobility Group Box 1), an inflammation mediator implicated in oxidative stress during periodontitis.

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Huntsman Cancer Institute investigators find a way to reduce infection after pancreatic surgery, discover the best treatment combination that’s cost effective for prostate cancer patients, and learn lung cancer patients receiving chemotherapy have more emergency department visits. They also found a genetic mutation that makes anemia more likely after chemotherapy, and a non-invasive way to remove brain tumors.

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Corticosteroids are used to increase very preterm infant survival rates and reduce health issues, however the effects on the infant’s long-term health have not been well understood, particularly in infants who exceed expectations and are born at term. The research suggests that many babies exposed to steroids avoid preterm birth, but new risks for other future health complications are introduced

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The cardiovascular polypill, developed by the Spanish National Centre for Cardiovascular Research (CNIC) and the pharmaceutical company Ferrer, has been included by the World Health Organization (WHO) in its List of Essential Medicines.

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Ion channels play a crucial role in many cellular processes, including neuronal communication, muscle contraction or cell proliferation. Most multi subunit ion channels exist in two functional states, either closed or open. During gating, one should expect that all subunits undergo conformational changes. The absence of intermediate conduction levels is surprising and asks for an explanation. A team of researchers from the University of Vienna and the Washington University in St. Louis created a smart model system to answer this important question. The study is currently published in Nature Communications.

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A team including University of Pittsburgh researchers uses computer modeling and new ways of employing enzymes to create never-before-seen amino acids.

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Systemic sclerosis is the scaring of multiple organs within the body resulting in difficulty in functioning for these organs. The disease can become deadly if the organ scaring isn’t treated properly. Researchers at the University of Michigan Health System have identified a protein in the disease that may be a new target for treatment.

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Two studies featured today at the 2023 AACC Annual Scientific Meeting & Clinical Lab Expo highlight advances that could boost the accuracy of marijuana tests and provide vital information for addressing the opioid epidemic.

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MD Anderson and Nexo announced a strategic research collaboration to rapidly advance new cancer therapies against previously undruggable targets.

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Scientists at the University of Colorado Anschutz Medical Campus have discovered what they believe to be the central mechanism behind cognitive decline associated with normal aging.

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The mass and composition of our bodies can significantly affect the way medications are metabolized and absorbed. Investigators at Cedars-Sinai found that inflammatory bowel disease (IBD) patients with higher levels of intra-abdominal visceral adipose tissue– a distinctive type of fat inside the abdomen −had lower rates of remission when treated with certain anti-inflammatory medications.

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Antibody therapies are only effective if the antibodies do what we want them to do. This research can help scientists determine if an antibody is likely to stick to something other than the intended target, which should lessen the amount of time wasted with overly sticky antibodies.

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The Association for Diagnostics & Laboratory Medicine (ADLM) is pleased to announce the recipients of its 2023 Top Corporate Supporter Award.

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You might not think of diabetes when you think of muscle function. But a common diabetes drug that regulates blood sugar can also prevent muscle atrophy and muscular fibrosis—which can help the elderly bounce back faster from injury or illness.

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A team of researchers led by Rensselaer Polytechnic Institute’s Jonathan S. Dordick, Ph.D., Institute Professor of Chemical and Biological Engineering, has illuminated a new possibility for the treatment and prevention of COVID-19 in research published in Communications Biology.

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Base editing technology invented at Rutgers, The State University of New Jersey, and exclusively licensed to Revvity, Inc. subsidiary Horizon Discovery, has been sub-licensed to biopharmaceutical company AstraZeneca to support its creation of cell therapies for the treatment of cancer and immune-mediated diseases.

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AACC, a global scientific and medical professional organization dedicated to better health through laboratory medicine, is pleased to announce a name change to the Association for Diagnostics & Laboratory Medicine.

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The secret to protecting your memory may be a staple of a bodybuilder’s diet. RUSH researchers recently discovered that a muscle-building supplement called beta-hydroxy beta-methylbutyrate, also called HMB, may help protect memory, reduce plaques and ultimately help prevent the progression of Alzheimer’s disease.

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A medication commonly used for abortion or miscarriage management is only available at six per cent of Hamilton, Ont. pharmacies, according to a McMaster University-led survey.