Adverse childhood experiences (ACEs) contribute to reduced vascular function and diminished sleep quality in young adults, according to a study at the University of Iowa.
Repeated use of cannabigerol caused a drop in the blood pressure of healthy mice, according to a new study at Pennsylvania State University College of Medicine.
What you eat might influence when you go to sleep, according to a new study of elite female college athletes.
The drug atogepant may help prevent migraines for people who have had no success with other preventive drugs, according to a preliminary study released April 20, 2023, which will be presented at the American Academy of Neurology’s 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023. The study involved people with episodic migraine, which is defined as having up to 14 headache days per month with migraine characteristics.
A study, led by University of Oregon neuroscientist Shawn Lockery, points to worms as a useful tool for understanding more about the many roles that cannabinoids naturally play in the body. And it could help researchers develop better drugs that target this system.
Astronomers are celebrating the Hubble Space Telescope’s 33rd launch anniversary with an ethereal photo of the star-forming region NGC 1333. Hubble’s colorful view unveils an effervescent cauldron of glowing gasses and dust stirred up and blown around by several hundred newly forming stars embedded within the dark cloud.
Two doses of an FDA-approved sleeping pill reduced levels of Alzheimer’s proteins in a small study of healthy volunteers led by researchers at Washington University School of Medicine in St. Louis. The study hints at the potential of sleep medications to slow or stop the progression of Alzheimer’s disease, although much more work needs to be done to confirm the viability of such an approach.
In people with no thinking and memory problems, a simple test may predict the risk of developing cognitive impairment years later, according to a study published in the April 19, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A drug called teriflunomide may delay first symptoms for people whose magnetic resonance imaging (MRI) scans show signs of multiple sclerosis (MS) even though they do not yet have symptoms of the disease. The preliminary study, released April 19, 2023, will be presented at the American Academy of Neurology’s 75th Annual Meeting, being held in person in Boston and live online from April 22-27, 2023. Called radiologically isolated syndrome, the condition is diagnosed in people who do not have MS symptoms but who have abnormalities in the brain or spinal cord called lesions, similar to those seen in MS.
People with epilepsy living in disadvantaged neighborhoods—areas with higher poverty levels and fewer educational and employment opportunities— may be more likely to have memory, thinking, and mental health problems compared to people with epilepsy living in neighborhoods with fewer disadvantages, according to new research published in the April 19, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that living in disadvantaged neighborhoods causes memory and mental health problems. It only shows an association.
What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south. In a new study, University of Illinois scientists show it’s possible to increase iron up to 35% and zinc up to 15% compared to parent lines simply by adding cell layers in the bran.
In early 2022, long-spined sea urchins in St. Thomas began to quickly die in large numbers. Scientists rushed in to find the cause and have discovered that a microscopic parasite swarms the body and spines of the urchins, eating them alive.
Today, foldable phones are ubiquitous. Now, using models that predict how well a flexible electronic device will conform to spherical surfaces, University of Wisconsin–Madison and University of Texas at Austin engineers could usher in a new era in which these bendy devices can integrate seamlessly with parts of the human body.
A new study by researchers at Washington University School of Medicine in St. Louis reveals that a connection between the body and mind is built into the structure of the brain. The study shows that parts of the brain area that controls movement are plugged into networks involved in thinking and planning, and in control of involuntary bodily functions such as blood pressure and heart rate.
A new study shows that cardiovascular strain begins at lower temperature and humidity levels than those that cause increases in the body’s core temperature, and could inform revisions to safety guidelines and policies that help protect people during heat waves.
The computational power of ecosystems -- or ecological reservoir computing -- is providing a new direction for rapidly developing AI technologies. Simulations have confirmed that ecological networks, such as prey-predator interactions, can efficiently process information and be utilized as a computational resource.
People who have an irregular heartbeat called atrial fibrillation that is treated with a procedure called catheter ablation may have a reduced risk of dementia compared to those who are treated with medication alone. The preliminary study released April 18, 2023, will be presented at the American Academy of Neurology’s 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023.
In a unique analysis of experimental data, nuclear physicists have made the first-ever observations of how lambda particles, so-called “strange matter,” are produced by a specific process called semi-inclusive deep inelastic scattering (SIDIS). What’s more, these data hint that the building blocks of protons, quarks and gluons, are capable of marching through the atomic nucleus in pairs called diquarks, at least part of the time.
Researchers have developed a drug that undercuts antibiotic resistance
Scrap aluminum can now be collected and transformed directly into new vehicle parts using an innovative process being developed by the automotive industry, in particular for electric vehicles.
University of Minnesota Twin Cities computer science researchers found that the nature of TikTok’s algorithm can have both positive and negative outcomes for users’ mental health and sense of belonging on the platform.
A new study led by researchers at The University of Texas MD Anderson Cancer Center discovered that co-occurring mutations in three tumor suppressor genes – KEAP1, SMARCA4 and CDKN2A – are linked with poor clinical outcomes in patients with KRAS G12C-mutant non-small cell lung cancer (NSCLC) treated with the KRAS G12C inhibitors adagrasib or sotorasib.
An international phase 3 clinical trial led by physicians at Washington University School of Medicine in St. Louis has shown that the investigational drug motixafortide — when combined with the standard therapy for mobilizing stem cells — significantly increases the number of stem cells that can be harvested, compared with treatment with the standard agent alone.
The CD70-targeting allogeneic chimeric antigen receptor (CAR) T cell therapy, ALLO-316, demonstrated encouraging response rates and disease control rates in patients with metastatic clear cell renal cell carcinoma (ccRCC), according to results of a Phase I trial led by researchers at The University of Texas MD Anderson Cancer Center and presented today at the American Association for Cancer Research (AACR) Annual Meeting 2023.
The first-in-class YAP/TEAD inhibitor VT3989 was well tolerated with durable antitumor responses in patients with advanced malignant mesothelioma and other tumors with NF2 mutations, according to results of a Phase I trial led by researchers at The University of Texas MD Anderson Cancer Center.
A regimen of pre-surgical immunotherapy and chemotherapy followed by post-surgical immunotherapy significantly improved event-free survival (EFS) and pathologic complete response (pCR) rates compared to chemotherapy alone for patients with operable non-small cell lung cancer (NSCLC), according to Phase III trial results presented today by researchers from The University of Texas MD Anderson Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2023.
New UCLA research suggests that a novel machine-learning technique known as "causal forest" was about five times more efficient than the current clinical practice of treating patients with high blood pressure.
New AI tool accurately predicts both overall survival and disease-free survival after colorectal cancer diagnosis. The model uses visual markers on pathology images to glean insights into a tumor’s genomic profile and predicts tumor behavior, disease progression, treatment response. The new model could help augment clinical decision-making. Because the AI tool relies on images alone, it could be particularly valuable for hospitals lacking the technology or expertise to perform sophisticated genomic profiling of tumor tissues.
Using rigorous and detailed collection methods, a University of Minnesota Twin Cities-led research team was able to place the remains of fossil apes, such as Morotopithecus, within detailed habitat reconstructions.
Using first-of-their-kind observations from the James Webb Space Telescope, a University of Minnesota Twin Cities-led team looked more than 13 billion years into the past to discover a unique, minuscule galaxy that could help astronomers learn more about galaxies that were present shortly after the Big Bang.
A lot of galaxies look like cotton balls when seen through a telescope. They are classified as elliptical galaxies. Now, with the help of Hubble, astronomers have estimated that the nearby elliptical galaxy M87 is "triaxial," or potato-shaped, if it could be viewed in 3D.
A new study sheds light on an understudied aspect of today’s opioid crisis: What happens to the cardiovascular health of babies exposed to opioids in the womb.
An international coalition of biomedical researchers co-led by Alexander Bick, MD, PhD, at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients’ risk of blood cancer. The technique, called PACER, led to the identification of a gene that, when activated, drives clonal expansion.
While legal cannabis products in the United States are required to report THC potency levels on their packaging those levels aren't necessarily accurate, which can have important implications for cannabis consumers. According to a new study from the University of Northern Colorado’s Department of Biological Sciences, researchers Mitchell McGlaughlin and Anna Schwabe found that the THC potency values reported on the packaging of cannabis samples from dispensaries across Colorado’s Front Range are substantially over-reported.
A researcher at the University of Kentucky is helping solve a mystery on the coast of North Carolina: Where did coal found on the shipwrecked Queen Anne’s Revenge come from? About 300 years ago, a band of pirates captured a French slave ship. Among those pirates was a man named Edward Thatch (also spelled as Teach) who would be better known as Blackbeard.
New technologies that can capture subtle changes in a patient’s voice may help physicians diagnose cognitive impairment and Alzheimer’s disease before symptoms begin to show, according to a UT Southwestern Medical Center researcher who led a study published in the Alzheimer’s Association publication Diagnosis, Assessment & Disease Monitoring.
A type of cell usually characterized as the brain’s support system appears to play an important role in OCD, providing a surprising new clue about potential therapeutic strategies for the disorder.
Managers who disconnect from work are rated as stronger leaders the next day
Researchers at Washington University School of Medicine in St. Louis have found a creative way to make a vaccine for norovirus, the leading cause of foodborne infections, by piggybacking on rotavirus, an unrelated virus for which there are already several highly effective vaccines.
Sleep is one of the most essential human activities — so essential, in fact, that if we don’t get enough sleep for even one night, we may struggle to think, react, and otherwise make it through the day. Yet, despite its importance for function and survival, scientists still don’t fully understand how sleep works.
A new groundbreaking image from one of the world’s most powerful telescopes that reveals the most detailed map of dark matter distributed across one quarter of the sky, and deep into the cosmos, offers scientists a perspective that may lead to new methods to demystify dark matter. The research that led to the image, completed by the Atacama Cosmology Telescope (ACT) collaboration, also provides further support to Einstein’s theory of general relativity, which has been the foundation of the standard model of cosmology for more than a century.
Aerosols particles in the atmosphere are an important factor in the Earth’s climate, but researchers lack information on these aerosols’ molecular composition, especially for aerosols during the day and night above agricultural fields. In this research, scientists examined secondary organic aerosols over agricultural fields in the Southern Great Plains in Oklahoma. They found that the aerosols’ composition and structure differ from day to night and that some aerosols are ultimately from urban sources.
Research led by scientists at UCLA Jonsson Comprehensive Cancer Center found that responses to a type of immunotherapy called PD-1 checkpoint blockade in patients with advanced melanoma depended on whether or not they had previously received another immunotherapy – CTLA-4 blockade – as well as other factors.
A potential drug successfully treats the severe form of nonalcoholic fatty liver disease in non-human primates — bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests. Nonalcoholic steatohepatitis (NASH) causes scarring and inflammation in the liver and is estimated to affect up to 6.5% of the global population.
Andrea Delgado, a Eugene P. Wigner Fellow at the Department of Energy’s Oak Ridge National Laboratory, is using quantum computing to help investigate the fundamental building blocks of the universe and to see whether there are particles yet to be found.
For more than 100 million Americans who are obese, bariatric surgery may reverse complications related to diabetes, including regenerating damaged nerves, a Michigan Medicine study shows. Researchers say the findings suggest that bariatric surgery likely enables the regeneration of the peripheral nerves and, therefore, may be an effective treatment for millions of individuals with obesity who are at risk of developing diabetes and peripheral neuropathy.
New research finds that global warming will bring stronger and more frequent hurricanes to U.S. coasts, up by a third compared to current levels.
The explosion of a star is a dramatic event, but the remains that the star leaves behind can be even more dramatic. A new mid-infrared image from NASA’s James Webb Space Telescope provides one stunning example. It shows the supernova remnant Cassiopeia A (Cas A), created by a stellar explosion 340 years ago from Earth's perspective. The image displays vivid colors and intricate structures begging to be examined more closely. Cas A is the youngest known remnant from an exploding, massive star in our galaxy, offering astronomers an opportunity to perform stellar forensics to understand the star’s death.
A community-based, evidence-based intervention system developed at the University of Washington has been linked to reduced handgun carrying rates among youth growing up in rural areas.
NASA’s James Webb Space Telescope recently observed Uranus, and the resulting image highlights a complex system of rings as well as a bright polar cap and likely storm clouds.
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