3D-bioprinted tissues can now be stored in the freezer until needed
Cell PressA major obstacle to widespread study and clinical use of 3D tissues is their short shelf-life, which may be anywhere from a just few hours to a few days.
A major obstacle to widespread study and clinical use of 3D tissues is their short shelf-life, which may be anywhere from a just few hours to a few days.
A drug combination can safely prevent transplanted stem cells (graft) from attacking the recipient’s (host) body, allowing them to develop into healthy new blood and immune cells, a new study shows.
How two of UC San Diego Health’s record-breaking 81 heart transplant recipients in 2021 forged a unique bond of mutual support.
Patients whose immune systems are weakened due to cancer, organ or bone marrow transplants, chronic diseases, or the medications used to treat these conditions may feel like they have enough on their plates without worrying about whether and when they should take an additional dose of COVID-19 vaccine and a flu shot.
University of Maryland Medicine, comprised of the University of Maryland Medical System (UMMS) and the University of Maryland School of Medicine (UMSOM) has announced that it will end the use of a long-standing clinical standard that factors a patient’s race into the diagnosis of chronic kidney disease (CKD).
University of Maryland Medicine will end use of a long-standing clinical standard that factors a patient’s race into the diagnosis of chronic kidney disease. The change could increase access to specialty care including transplant for thousands of Black people living with advanced kidney disease.
Clonal hematopoiesis, a condition in which mutations associated with blood cancers are found in the blood of healthy people, is common with aging. When looking for appropriate stem cell/bone marrow donors, clinicians tend to stay away from older donors with clonal hematopoiesis (CH) because of concerns about passing potentially premalignant stem cells to the recipient.
Physicians at Washington University School of Medicine in St. Louis and Massachusetts General Hospital/Harvard Medical School in Boston have received a seven-year, $22 million grant from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) to help lead a multicenter clinical trial evaluating whether a novel immunosuppressant can reduce the risk of organ rejection after a lung transplant.
Patients with a rare immunodeficiency disorder who are treated with lifelong immunoglobulin replacement therapy (IRT) have a lower risk of premature death than patients treated with a hematopoietic stem cell transplant (HSCT), but they also have a reduced quality of life and must assume a substantial financial burden, according to a new study led by Children’s Hospital of Philadelphia (CHOP). Using a computational model to calculate the costs and benefits of IRT and HSCT for patients with agammaglobulinemia, the researchers concluded that the high cost of IRT in the U.S. undermines its cost-utility, particularly when compared to Canada and European countries, where the cost of IRT is nearly a third of what it is in the U.S.
Loyola Medicine has completed Illinois' first heart transplant using a newly developed cardiac transport system. The Paragonix SherpaPak® System aims to change the way hearts are transported during transplant, utilizing a canister that monitors temperature rather than packing the heart in ice.
ALEXANDRIA, Va. – A new study has found that people with nonalcoholic fatty liver disease (NAFLD) cirrhosis who are not overweight and are on a waiting list for a liver transplant fare worse than overweight patients before and after transplant surgery. The study concludes that these at-risk patients need better nutritional counseling and other interventions to help prevent serious health problems while they are waiting for liver transplant.
ALEXANDRIA, Va. – A new study has found that the proportion of older Americans who need a liver transplant (LT) has sharply increased in recent years, often due to the rising number of cases of nonalcoholic steatohepatitis (NASH). As the U.S. population ages, researchers estimate that more patients aged 65 or older will need an LT than ever before.
Studying mice, researchers at Washington University School of Medicine in St. Louis have developed a method of stem cell transplantation that does not require radiation or chemotherapy. Instead, the strategy takes an immunotherapeutic approach, combining the targeted elimination of blood-forming stem cells in the bone marrow with immune-modulating drugs to prevent the immune system from rejecting the new donor stem cells.
在家人齐聚共度节假日之际,免疫力低下的患者务必采取额外的措施,保护自己免于罹患COVID-19(2019 冠状病毒病),这一点很重要。免疫系统受损的人患上COVID-19重症的风险更高。这些人包括癌症患者、接受了移植手术并正在服用免疫抑制药物的患者,以及感染艾滋病毒/艾滋病的晚期和未接受过治疗的患者。
مدينة روتشستر، ولاية مينيسوتا- بينما تتجمع العائلات لقضاء العطلات، من المهم للمرضى الذين يعانون من نقص المناعة اتخاذ خطوات إضافية للمساعدة في حماية أنفسهم من فيروس كورونا المستجد (كوفيد-19). الأشخاص المصابون بضعف في جهاز المناعة عرضة بشكل أكبر لخطر المرض الشديد جرَّاء فيروس كورونا المستجد (كوفيد-19
Conforme as famílias se reúnem para as festas de final de ano, é importante que os pacientes imunocomprometidos tomem medidas extras para ajudar a se proteger da COVID-19. Pessoas com o sistema imunológico enfraquecido correm maior risco de adoecer gravemente com a COVID-19.
Dada la proximidad de las reuniones familiares para celebrar las festividades, es importante que los pacientes con compromiso inmunitario tomen medidas adicionales para protegerse contra la COVID-19.
As families prepare to gather later this month for Thanksgiving, it is important for patients who are immunocompromised to take extra steps to protect themselves from becoming infected with COVID-19. People who are immunocompromised have weakened immune systems, which means they have a higher risk of becoming severely ill from COVID-19.
• People who are on dialysis or who have undergone kidney transplantation have immune system–related differences compared with people with normal kidney function, and these differences are further amplified by SARS-CoV-2 infection. • The findings may help explain why these individuals face a higher risk of dying from COVID-19. • Results from the study will be presented online at ASN Kidney Week 2021 November 4–November 7.
Today, the American Society of Nephrology (ASN) announced the Barbara T. Murphy Endowed Lectureship. Established by Verici Dx (LSE: VRCI), Renalytix (LSE RENX and Nasdaq RNLX), and the American Society of Transplantation (AST), the new lectureship will honor Dr. Murphy’s legacy as a leader in transplant immunology and medicine by recognizing advances in kidney transplantation.
New research presented this week at ACR Convergence, the American College of Rheumatology’s annual meeting, shows that people with systemic autoimmune diseases do as well after lung or heart-lung transplants as those without any systemic causes of end-stage lung disease.
A growing number of hospitals have implemented patient blood management programs to reduce unnecessary blood transfusions and costs. A study published in Mayo Clinic Proceedings finds that such a program can not only substantially reduce transfusion use, but also reduce length of hospital stays and in-hospital adverse outcomes.
Hassenfeld Children’s Hospital at NYU Langone and the NYU Langone Transplant Institute reached a historic, first-ever milestone when surgeons replaced the lungs of a 16-year-old girl with cystic fibrosis.
Registrations for the national organ transplant waiting list related to alcoholic hepatitis as well as the number of deceased donor liver transplants for the inflammatory liver condition rose significantly during the pandemic, Michigan Medicine researchers found.
Researchers report waiting list registrations and deceased donor liver transplants in the U.S. for alcoholic hepatitis, which can develop after a short period of alcohol misuse, increased during COVID-19, exceeding volumes forecasted by pre-COVID-19 trends, while trends for alcohol-related cirrhosis and non-alcohol-associated liver disease remained unchanged.
People with liver cancer awaiting transplantation could benefit from non-invasive radiation treatments but are rarely given this therapy, according to a new analysis of U.S. national data. Findings will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting.
The first investigational transplantation of a genetically engineered, nonhuman kidney to a human body was recently completed at NYU Langone Health—marking a major step forward in potentially utilizing an alternative supply of organs for people facing life-threatening disease.
In a study of children on the U.S. kidney transplant list from 2008 to 2019, researchers found no racial and ethnic disparities regarding time on the waitlist until transplantation either before or after a 2014 policy change.
Researchers at the University of Michigan Health Rogel Cancer Center have identified a drug that, when given along with a bone marrow transplant, drops the risk of leukemia recurring by 20% among the high-risk patients.
Keck Medicine of USC treatment plan significantly reduces hospitalizations and deaths of liver and kidney transplant recipients with COVID-19
Clinical equations that estimate patients’ kidney function include an adjustment for Black race. This survey-based study found that U.S. transplant centers agree that this adjustment is unsatisfactory.
Cesarean birth rates are on the rise, and this is especially true for high-risk pregnant women who have undergone organ transplantation. While cesarean births account for 31% of all deliveries in the United States, the rate of cesarean births for pregnant people with kidney transplants is 62.6% and 44.6% for liver transplants.
Physicians recommend that patients with pulmonary hypertension avoid pregnancy, given the high risk of death for the mother and baby. However, Candice Cruise was unaware of her condition until she reached 21 weeks of pregnancy.
A recent study examined the spectrum of antibody responses—including IgG, IgM, and IgA antibodies—in kidney transplant recipients infected with the virus that causes COVID-19
In a study published today in the American Journal of Transplantation, Johns Hopkins Medicine researchers say that children between the ages of 12 and 18 who have received solid organ transplants appear to mount a more robust immune response than their adult counterparts after a standard two-dose vaccination regimen against SARS-CoV-2, the virus that causes COVID-19.
An analysis of national data shows that kidney transplant recipients and individuals with kidney failure face a high risk of dying from COVID-19.
Today, advocates of the American Society of Nephrology (ASN) and 19 other kidney health professional and patient organizations are meeting with their congressional delegations, calling on them to enact policies to improve kidney health
In a worldwide pediatric study, researchers from Children’s Hospital Los Angeles show the clear benefit of using living donor liver tissue for transplants.
People who have received organ transplants face an elevated risk of developing cancer, primarily due to immunosuppression from medications to prevent organ rejection, as well as underlying medical conditions.
The Society of Thoracic Surgeons is highlighting two particularly interesting stories from COVID survivors who were on ECMO for months, with one patient eventually underdoing a double lung transplantation.
As head of the transplant program, Dr. Jain will work with the hospital's more than 30 pediatric subspecialists.
糖尿病的治疗方式在过去十年来取得了长足进展。糖尿病是一种可能导致严重并发症的终身慢性疾病。尽管治疗方式有所进展,但许多糖尿病患者仍在与疾病作斗争。
خلال العقد الماضي أُحرِزَت العديد من التطورات في علاجات السكري. مرض السكري هو مرض مزمن مع احتمال حدوث مضاعفات كبيرة. وعلى الرغم من التطورات المحرزة، يعاني الكثيرون من مرضى السكري جرّاء إصابتهم بالمرض.
Muitos avanços foram feitos em relação aos tratamentos da diabetes ao longo da década passada. A diabetes é uma doença crônica com cuidados necessários por toda a vida, com potencial para complicações significativas. Apesar dos avanços, muitas pessoas com diabetes lutam contra a doença.
El tratamiento de la diabetes ha avanzado mucho en la última década. La diabetes es una enfermedad crónica que dura toda la vida y causa complicaciones importantes. Pese a los avances, muchas personas diabéticas tienen problemas.
After more than 50 days on advanced life support, a multi-disciplinary team at UC San Diego Health helps a patient who contracted COVID-19 become a candidate for a successful double lung transplant. The transplant surgery was the first in the region performed on a COVID-19 patient.
Expert Q&A: Do breakthrough cases mean we will soon need COVID boosters? The extremely contagious Delta variant continues to spread, prompting mask mandates, proof of vaccination, and other measures. Media invited to ask the experts about these and related topics.
The FDA and CDC have just approved and recommended an additional dose of mRNA COVID-19 vaccines for moderately and severely immunocompromised people. Who should get it?