Feature Channels: Vaccines

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A college degree was far from the minds of Joshua and Caleb Marceau growing up on a small farm on the Flathead Indian Reservation in rural northwestern Montana.

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A recent study published in Muscle & Nerve created by the Centers for Disease Control and Prevention/Food and Drug Administration examined the prevalence of Miller-Fisher syndrome (MFS) occurring after vaccination in the United States.

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A recent study published in Muscle & Nerve appears to show that the influenza vaccination is safe to use for those with autoimmune neuromuscular disorders.

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Rates of new anal cancer diagnoses and deaths related to human papillomavirus (HPV), the most common sexually transmitted infection, have increased dramatically over the last 15 years, according to researchers at The University of Texas Health Science Center at Houston (UTHealth). The results of their study will be published in the November issue of the Journal of the National Cancer Institute.

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Wistar and Leiden University Medical Center (LUMC) formalized a memorandum of understanding between the two institutions to explore a postdoctoral training exchange program in immunology, cancer research and vaccine biology. The Wistar-Schoemaker International Postdoctoral Fellowship would bring recent Ph.D. graduates trained at LUMC to Wistar to advance their research education under the mentorship of cutting-edge biomedical research leaders.

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Kathryn Edwards, MD, who holds the Sarah H. Sell and Cornelius Vanderbilt Endowed Chair in Pediatrics and is a professor of Pediatrics at Vanderbilt University School of Medicine, is the recipient of the 2020 John Howland Award, the highest honor given by the American Pediatric Society (APS).

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Weather conditions and cold and flu viruses can make it more difficult for you to stay healthy and safe during winter months.

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New research from Dr. Luis M. Schang and his group at the Baker Institute for Animal Health has identified a new mechanism that plays a role in controlling how the herpes virus alternates between dormant and active stages of infection.

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In a year that has seen the largest measles outbreak in the US in more than two decades, the role of social media in giving a platform to unscientific anti-vaccine messages and organizations has become a flashpoint.

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In support of World Pneumonia Day, Nov. 12, the Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a member, calls for an end to preventable pneumonia deaths, ensuring equitable access to interventions for prevention and control of pneumonia.

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According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, the live zoster virus vaccine is safe for people who are currently receiving tumor necrosis factor inhibitor (TNFi) biologic therapies for various indications.

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Nuevo estudio muestra que las vacunas contra la alergia (inmunoterapia subcutánea) pueden ser efectivas para reducir síntomas de PFAS para pacientes pediátricos.

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Below are summaries of recent Fred Hutch research findings with links for additional background and media contacts.

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Study shows measles wipes out 20 to 50 percent of antibodies against an array of viruses and bacteria, depleting a child’s previous immunity Measles-ravaged immune system must “relearn” how to protect the body against infections Study details mechanism and scope of this measles-induced “immune amnesia” Findings underscore importance of measles vaccination, suggesting those infected with measles may benefit from booster shots of all previous childhood vaccines

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A Cooperative Research Center (CRC) has been established by the National Institutes of Health at three institutions including the Lawrence Livermore National Laboratory (LLNL), the University of California, Irvine (UCI) and the University of California, Davis, with a single goal to enhance and accelerate the development of vaccines for Chlamydia trachomatis genital infections.

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A human antibody that protects mice against a wide range of lethal flu viruses could be the key to a universal vaccine and better treatments for severe flu disease, according to a new study from Washington University School of Medicine in St. Louis, Icahn School of Medicine at Mount Sinai in New York City, and Scripps Research in La Jolla, Calif.

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Physicians at the University of Alabama at Birmingham want to encourage everyone to get a flu shot between now and early November.

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A universal influenza vaccine with the potential to be longer lasting and more effective than commercially available vaccines is destined for human clinical trials, thanks to a $17.9 million grant from the National Institute of Allergy and Infectious Diseases.

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A cooperative research center that aims to develop vaccines for chlamydia has been established by the National Institutes of Health at Lawrence Livermore National Laboratory (LLNL). The center includes two University of California campuses – Irvine and Davis.

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A new study by researchers at Washington University School of Medicine in St. Louis indicates a way for cancer immunotherapy to spur a more robust immune response. Such knowledge could lead to the development of better cancer vaccines and more effective immunotherapy drugs called checkpoint inhibitors.

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UAB’s Division of Infectious Diseases researchers have been awarded a three-year contract with a total potential amount of $10 million to study the efficacy of the vaccine Bexsero — already licensed to prevent meningitis — in protecting vulnerable populations from infection with the bacteria that causes gonorrhea.

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An analysis and related commentary published in Clinical Infectious Diseases today provide in-depth examination of the deplorable and dangerous conditions in U.S. immigrant detention centers where seven children have died in the last 10 months. Together, the articles underscore an urgent imperative repeatedly cited by ours, and other societies of medical professionals, to investigate and remedy violations of human rights and the most basic standards of public health, infection control and medical practice that have been demonstrated in these facilities.

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The AACI Public Policy Resource Library aims to enable cancer centers and partners in the cancer advocacy community to share resources to foster collaboration, promote cancer prevention, and spur the development of sound public health policy at the state and local level.

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A team led by researchers at the Icahn School of Medicine at Mount Sinai is getting closer to a universal flu vaccine using a novel approach they’ve developed called chimeric hemagglutinin (cHA).

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You cannot really germ-proof your home, but you can clean and disinfect things to improve your chances of preventing the flu.

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Anecdotes, fake news and social media have created a skeptical and misinformed public who is rejecting the facts. A commentary says that medical researchers must help the public understand the rigorous process of science and help them to discern an anecdote from peer-reviewed scientific results. The best way to do this? By continuing to ensure integrity, rigor, reproducibility and replication of their science and to earn the public’s trust by being morally responsible and completely free of any influences.

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Barbara Masser, MD, Medical Director of Ambulatory Emergency Medicine at Beth Israel Deaconess Medical Center, shares some insight on whether or not you may need a flu test.

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Hackensack Meridian Health Southern Ocean Medical Center will once again host its annual Women’s Health Night on Wednesday, October 30, 2019. The free event will take place from 5:30 p.m. to 8:30 p.m. on the first floor of the hospital in Manahawkin.

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Cases of the flu are already on the rise around the nation as flu season begins. Johns Hopkins Medicine experts say now is the time to fight against the flu as the number of people getting sick from the potentially life-threatening virus will increase in the coming months. Doctors recommend everyone 6 months and older get the flu vaccine each year to prevent the virus or reduce the seriousness if you do get sick.

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New research suggests a vaccine that blocks a digestive hormone may slow the spread of pancreatic cancer, potentially increasing survival rates. The study, published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology, was chosen as an APSselect article for October.

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The Unity Consortium is thrilled to welcome newest member, Ethan Lindenberger, a 19-year old American activist known for his opposition to vaccine misinformation efforts.

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As tumor cells multiply, they often spawn tens of thousands of genetic mutations. Figuring out which ones are the most promising to target with immunotherapy is like finding a few needles in a haystack. Now a new model hand-picks those needles so they can be leveraged in more effective, customized cancer vaccines.

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A vaccine for the common and sometimes deadly RSV (respiratory syncytial virus) has been elusive, but scientists say a new discovery puts them much closer to success.

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Penn Medicine study shows patients who use online platforms connected to their health records are more likely to take preventative health measures.

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Get your flu shot now, especially if you're healthy. Dr. John Lynch, medical director of infection control at Harborview Medical Center, explains the idea of "herd immunity." "The more people who get vaccinated, the more of a shield there is against the virus from getting into the community,' he says.

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After a rigorous vetting process, Johns Hopkins University officials announced today their selection of Vines Architecture to lead the planning stages, known as a feasibility study, for a multidisciplinary building that will honor the legacy of Henrietta Lacks.

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Amanda Simanek can also talk about new recommendations for children to receive two doses of this year’s vaccine.

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As the 2019–20 flu season gets underway, Johns Hopkins Medicine experts will be available throughout the season to talk with your newsroom about the epidemiology of this year’s virus, as well as provide important information about this year’s vaccine. Flu cases have already begun to appear in the U.S. Flu activity tends to increase in October and can run as late as May.

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Infectious disease experts David Cennimo at Rutgers New Jersey Medical School and Tanaya Bhowmick at Rutgers Robert Wood Johnson Medical School discuss this year’s flu season, the effectiveness of the vaccine and how you can protect yourself.

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NIH contract award of up to $132 million will further ongoing efforts to develop a long-lasting vaccine

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The University of Georgia has signed a contract with the National Institutes of Health for an initial award of $8 million to develop a new, more advanced influenza vaccine designed to protect against multiple strains of influenza virus in a single dose. The total funding could be up to $130 million over seven years if all contract options are exercised.

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As part of a massive national effort to improve and modernize flu shots, the Duke Human Vaccine Institute has received three research contracts from the National Institute of Allergy and Infectious Diseases (NIAID), with an initial award of approximately $29.6 million in first-year funding.

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In mid-August 2019, human clinical trials were halted in the current Ebola epidemic that has claimed more than 2,100 lives in Africa. The findings resulted in the discontinuation of two of the drugs in the trial. Future patients will be randomly assigned to receive either REGN-EB3 (Regeneron) or mAb114 (Ridgeback Biotherapeutics) in an extension phase of the study. Texas Biomedical Research Institute scientists in the Institute’s Biosafety Level 4 contract research program conducted preclinical testing of several of the compounds in the trial, working with Regeneron and the Biomedical Advanced Research and Development Authority (BARDA).

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Wistar was awarded two major grants totaling more than $12 million from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, to fund an international multidisciplinary clinical research consortium spearheaded by Wistar’s HIV Research Program.

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Value in Health, the official journal of ISPOR—the professional society for health economics and outcomes research, announced today the publication of research demonstrating that discrete choice experiments are able to predict real-world healthcare choices.

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The National Institute of Allergy and Infectious Diseases research contract is one of the largest ever awarded to UMSOM and includes an initial award of approximately $2.5 million to conduct clinical testing of influenza vaccines. Total funding over seven years could be as much as $201 million if all options are exercised in the NIAID contract.

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A novel vaccine at Penn Medicine protected almost all animal subjects exposed to the herpes virus

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The UM School of Medicine's Contract awarded by the National Institute of Allergy and Infectious Diseases could fund up to $201 Million in influenza research over seven years.

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Spending bills released by Senate Appropriations Committee Wednesday demonstrate encouraging recognition of some of the most urgent health challenges threatening individual and public health at home and abroad. At the same time, the bills fall short of the comprehensive commitments necessary to fully effective responses.