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Newswise: Decoding calcifications in breast cancer: towards personalized medicine
Released: 13-Aug-2024 10:05 AM EDT
Decoding calcifications in breast cancer: towards personalized medicine
Chinese Academy of Sciences

A pivotal study uncovers the molecular signatures of mammographic calcifications in hormone receptor-positive, HER2-negative breast cancer.

Newswise: Tuskan named DOE Office of Science Distinguished Scientist Fellow
Released: 13-Aug-2024 8:05 AM EDT
Tuskan named DOE Office of Science Distinguished Scientist Fellow
Oak Ridge National Laboratory

Gerald A. Tuskan, a Corporate Fellow and director of the Center for Bioenergy Innovation, or CBI, at the Department of Energy’s Oak Ridge National Laboratory, has been selected as a DOE Distinguished Scientist Fellow, one of the highest honors bestowed by the agency’s Office of Science for outstanding scientific leadership and research community engagement.

Released: 13-Aug-2024 7:35 AM EDT
Statement on Passage Genetic Testing Legislation in Illinois
Susan G. Komen

Susan G. Komen applauds the Illinois General Assembly and Governor J.B. Pritzker on the passage of SB 2697, which provides expanded coverage of genetic testing for the breast cancer community.

   
Newswise: New Research Uncovers the Spatial Gene Expression of Major Cell Types from the Stems of Sorghum
Released: 12-Aug-2024 3:05 PM EDT
New Research Uncovers the Spatial Gene Expression of Major Cell Types from the Stems of Sorghum
Environmental Molecular Sciences Laboratory - EMSL

A multi-institutional team of researchers developed a protocol to isolate cell types for deep sequencing analysis. They successfully generated the first comprehensive gene expression atlas of the sorghum stem, which revealed cell-type-specific expression patterns, pathways, and underlying regulatory networks.

Newswise: Comprehensive atlas of normal breast cells offers new tool for understanding breast cancer origin
Released: 12-Aug-2024 12:05 PM EDT
Comprehensive atlas of normal breast cells offers new tool for understanding breast cancer origin
Indiana University

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have completed the most extensive mapping of healthy breast cells to date. These findings offer an important tool for researchers at IU and beyond to understand how breast cancer develops and the differences in breast tissue among genetic ancestries.

Newswise: Scientists identify genes linked to relapse in the most common form of childhood leukemia
Released: 12-Aug-2024 11:50 AM EDT
Scientists identify genes linked to relapse in the most common form of childhood leukemia
St. Jude Children's Research Hospital

Scientists from St. Jude Children’s Research Hospital, Seattle Children’s and the Children’s Oncology Group (COG) have identified novel genetic variations that influence relapse risk in children with standard risk B-cell acute lymphoblastic leukemia (SR B-ALL), the most common childhood cancer.

Newswise: Taking a ‘One in a Million’ Shot to Tackle Dopamine-Linked Brain Disorders
Released: 12-Aug-2024 8:30 AM EDT
Taking a ‘One in a Million’ Shot to Tackle Dopamine-Linked Brain Disorders
Florida Atlantic University

With the help of a tiny, transparent worm called Caenorhabditis elegans, researchers have identified novel players in dopamine signaling by taking advantage of a powerful platform generated via the Million Mutation Project for the rapid identification of mutant genes based on their functional impact.

   
Released: 9-Aug-2024 11:05 AM EDT
AI accurately diagnoses genetic condition from facial photographs
Yale School of Medicine

A Yale School of Medicine team reports in a new study that an artificial intelligence (AI) model was able to reliably diagnose people living with Marfan Syndrome from a simple facial photograph.

Newswise: The molecular shield: how tea plants combat drought through protein phosphorylation
Released: 9-Aug-2024 10:05 AM EDT
The molecular shield: how tea plants combat drought through protein phosphorylation
Chinese Academy of Sciences

A pivotal study has discovered a protein phosphorylation mechanism that plays a critical role in the negative regulation of flavonoid biosynthesis in tea plants (Camellia sinensis) during drought stress.

Newswise: Unlocking the genetic secrets of strawberries for superior fruit quality
Released: 9-Aug-2024 10:05 AM EDT
Unlocking the genetic secrets of strawberries for superior fruit quality
Chinese Academy of Sciences

Strawberries, treasured for their flavor and health benefits, have been at the forefront of breeding programs targeting enhanced sensory and nutritional profiles. Despite advances, the intricate genetic makeup of these fruits has complicated efforts to improve them. This new study offers a breakthrough by identifying key genetic markers and candidate genes that control quality traits, enabling more precise and successful breeding strategies to cultivate strawberries that are juicier, more vibrant, and longer-lasting.

Newswise: Smooth sailing for eggplant: breakthrough in understanding prickle formation
Released: 8-Aug-2024 11:05 AM EDT
Smooth sailing for eggplant: breakthrough in understanding prickle formation
Chinese Academy of Sciences

Scientists have discovered the gene responsible for prickles in eggplants, a trait that complicates farming. Using advanced genetic techniques, they identified the Prickly Eggplant (PE) gene on chromosome 6 and pinpointed SmLOG1 as the key factor. CRISPR-Cas9 gene editing confirmed that disabling SmLOG1 eliminates prickles, paving the way for prickle-free eggplant varieties. This breakthrough not only sheds light on prickle development but also promises to streamline eggplant cultivation and harvesting, benefiting the agricultural industry.

Newswise: Flow of sweetness: key sugar transporters identified for enhanced Camellia seed growth
Released: 8-Aug-2024 11:05 AM EDT
Flow of sweetness: key sugar transporters identified for enhanced Camellia seed growth
Chinese Academy of Sciences

A recent study investigates the intricate mechanisms of sugar import in developing seeds of Camellia oleifera. By identifying key sugar transporters and analyzing their roles, the research provides significant insights into the molecular regulation of seed development. The findings highlight how these transporters, working alongside sucrose-metabolizing enzymes, facilitate efficient sugar import and partitioning. This study not only advances our understanding of seed development in Camellia oleifera but also suggests potential strategies to enhance seed yield and quality in this important oil-producing plant.

Newswise: Battling bugs with big data: sweetpotato's genomic-metagenomic pest shield
Released: 8-Aug-2024 10:05 AM EDT
Battling bugs with big data: sweetpotato's genomic-metagenomic pest shield
Chinese Academy of Sciences

Sweetpotato, a staple in combating global hunger, faces significant threats from pests like whiteflies and weevils, impacting plant growth and yields. A new study harnesses the power of genomic and metagenomic data to predict pest abundance and identify key genes that could fortify the plant's defense mechanisms.

Newswise: Beyond the Genome: Project to Map DNA Modifications and Gene Activity Across Lifespan, Generations
Released: 8-Aug-2024 9:05 AM EDT
Beyond the Genome: Project to Map DNA Modifications and Gene Activity Across Lifespan, Generations
University of Utah Health

Long-term, heritable changes in gene activity fundamentally shape our biology, trigger many of our diseases, and set the clock on how we age. Now, a team of U of U Health scientists is starting an ambitious project to map these changes across the entire human genome.

   
Newswise: Heat Stress Survival: Unraveling the HsfA2-ACTIN Dynamics in Lily Varieties
Released: 8-Aug-2024 3:05 AM EDT
Heat Stress Survival: Unraveling the HsfA2-ACTIN Dynamics in Lily Varieties
Chinese Academy of Sciences

A research team has identified that the heat stress transcription factor HsfA2 and actin-interacting protein (AIP) LACTIN interact at the protein level in Lilium longiflorum 'White Heaven', mediating gene expression and protecting cells from heat stress.

Newswise: Mild Drought Preconditioning Boosts Tiller Growth and Resilience in Perennial Ryegrass
Released: 8-Aug-2024 3:05 AM EDT
Mild Drought Preconditioning Boosts Tiller Growth and Resilience in Perennial Ryegrass
Chinese Academy of Sciences

A research team discovered that drought preconditioning accelerates tiller bud initiation and outgrowth in perennial ryegrass plants.

Released: 7-Aug-2024 12:00 PM EDT
MD Anderson Research Highlights for August 7, 2024
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments at MD Anderson include insights into evolutionary cellular adaptations to environmental stressors, potential targets to overcome trouble swallowing in head and neck cancer patients treated with radiation therapy, a promising chemotherapy-free combination treatment for patients with a subset of acute lymphocytic leukemia, a single-cell atlas for stomach cancer metastasis, encouraging results of a PARP inhibitor on patients with advanced cancers and specific DNA damage repair mutations, and a liquid biopsy signature that could improve early pancreatic cancer detection.

   
Newswise: Vitis genomics: charting the path to resilient grape varieties
Released: 7-Aug-2024 10:05 AM EDT
Vitis genomics: charting the path to resilient grape varieties
Chinese Academy of Sciences

Recent advancements in grape genomics have significantly enhanced our understanding of grapevine biology and breeding. By sequencing over 44 grape genomes, researchers have identified key genes related to disease resistance, berry quality, and stress tolerance.

Newswise: Cucumber's genetic core: new insights into centromere structures
Released: 7-Aug-2024 10:05 AM EDT
Cucumber's genetic core: new insights into centromere structures
Chinese Academy of Sciences

The study provides significant insights into cucumber centromeres by identifying key centromeric satellite sequences and retrotransposons. Researchers found notable differences in centromeric DNA between wild and cultivated cucumbers, highlighting the impact of domestication.



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