Researchers at the University of Kentucky’s Sanders-Brown Center on Aging recently received a five-year grant renewal of their MarkVCID program from the National Institutes of Health (NIH). The award total is more than $6 million.
As people age, inflammation within their immune system increases, damaging cells. A new study shows that people who consumed an anti-inflammatory diet that includes more fruits, vegetables, beans, and tea or coffee, had a lower risk of developing dementia later in life. The research is published in the November 10, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.
New research provides a better understanding of the mechanisms behind the development of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, and points to a potential treatment strategy.
Researchers at the University of Toronto (U of T) and Unity Health Toronto have demonstrated that repeated listening to personally meaningful music induces beneficial brain plasticity in patients with mild cognitive impairment or early Alzheimer’s disease.
Despite the belief that early diagnosis of Alzheimer’s disease and other dementias is crucial, a new Rutgers study found that the diagnosis may unintentionally impact social relationships and activity.
A new study found that people with higher cumulative estrogen exposure over their lifetime had greater brain volumes and fewer indicators of brain disease on their brain scans in midlife . The research is published in the November 3, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A new study suggests that healthy older people who eat two or more servings of fish a week, including salmon, tuna and sardines, may have a lower risk later in life of developing vascular brain disease, a group of conditions that affect blood flow and blood vessels in the brain. The research is published in the November 3, 2021, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study found that eating a diet rich in fish had the greatest protective effect on people younger than 75 years old.
Researchers leading the Tau Nex Gen Trial — a worldwide clinical trial aimed at finding treatments for Alzheimer’s disease — are modifying an arm of the trial to target two brain proteins: amyloid and tau. A part of DIAN-TU, the trial originally was announced with a focus on drugs that target tau.
A study by UT Southwestern researchers finds that changing the biochemistry of parts of brain cells abolished the formation of amyloid beta plaques in a mouse model of Alzheimer’s disease. The finding, published in eLife, might eventually lead to treatments that prevent the memory-robbing condition in humans.
Researchers tested the effectiveness of affordable, interactive robotic pet cats to improve mood, behavior and cognition in older adults with mild to moderate dementia.
A new study led by researchers at UCLA Health has found that women over the age of 50 who had breastfed their babies performed better on cognitive tests compared to women who had never breastfed. The findings, published in Evolution, Medicine and Public Health, suggest that breastfeeding may have a positive impact on postmenopausal women’s cognitive performance and could have long-term benefits for the mother’s brain.
Older adults who sleep short or long experienced greater cognitive decline than those who sleep a moderate amount, even when the effects of early Alzheimer’s disease were taken into account, according to a study by researchers at Washington University School of Medicine in St. Louis.
Infrared light therapy might have the potential to help people living with dementia, according to researchers.
University of Virginia School of Medicine researchers have revealed a vital but previously unknown role for immune cells that protect the brain from disease and injury: The cells, known as microglia, also help regulate blood flow and maintain the brain’s critical blood vessels.
Research conducted by the Ph.D student Mohamed Raâfet Ben Khedher and the postdoctoral researcher Mohamed Haddad of the Institut national de la recherche scientifique (INRS) has shown that an oxidation-antioxidant imbalance in the blood is an early indicator of Alzheimer's disease, rather than a consequence.
New research from the Florida State University College of Medicine found that changes in the brain associated with Alzheimer’s disease are often visible early on in individuals with personality traits associated with the condition.
An anti-viral gene that impacts the risk of both Alzheimer’s disease and severe Covid-19 has been identified by a UCL-led research team.
A recently released paper from the Department of Physiology and Sanders-Brown Center on Aging at the University of Kentucky College of Medicine suggests that your genetics can influence your response to Alzheimer’s disease pathology.
Researchers with the John P. Hussman Institute for Human Genomics (HIHG) at the University of Miami Miller School of Medicine, will serve as principal investigators for a major five-year initiative with Vanderbilt University Medical Center and the University of Southern California, to pool and standardize research data gathered from individuals in multiple studies of Alzheimer’s disease and related dementias (ADRD).
Cells that normally nourish healthy brain cells called neurons release toxic fatty acids after neurons are damaged, a new study in rodents shows. This phenomenon is likely the driving factor behind most, if not all, diseases that affect brain function, as well as the natural breakdown of brain cells seen in aging, researchers say.
Some devastating diseases, like Alzheimer's and autoimmune conditions, are hard to diagnose correctly because doctors don’t yet know what genes or molecules to look for. But a new technique inspired by the Star Trek tricorder can spot disease without the clues, using infrared light and machine learning.
Poor sleep quality is associated with Alzheimer’s disease (AD). This award will support the development of non-invasive methods to monitor sleep quality, which will provide a key advance to assess if new candidate drugs truly restore sleep quality in the brain. These indicators of sleep brain quality could speed up the development of sleep treatments to improve the quality of life and the progression of AD. Because sleep disruption also occurs in other dementias, the indicators developed could positively impact additional diseases.
Lu Sun, Ph.D., Assistant Professor of Molecular Biology at UT Southwestern, has been awarded $1.5 million from the National Institutes of Health (NIH) to study interactions between neurons and glial cells in the brain, which could provide insight into the causes of neurological disorders.
Lorena Saelices Gomez, Ph.D., Assistant Professor of Biophysics and in the Center for Alzheimer’s and Neurodegenerative Diseases at UT Southwestern, has been awarded $1.5 million from the National Institutes of Health (NIH) to determine the structure of amyloids, key proteins that have been tied to diseases including Alzheimer’s and ATTR amyloidosis.
Individuals who are diagnosed with high blood pressure at ages 35-44 had smaller brain size and were more likely to develop dementia compared to people who had normal blood pressure, according to new research published today in Hypertension, an American Heart Association journal.
The results of three new studies indicate there could be new treatments for Alzheimer’s and stroke.
Vanderbilt University Medical Center has been awarded a five-year, $31.7 million grant by the National Institute on Aging, part of the National Institutes of Health (NIH), to harmonize research data gathered on human subjects in scores of disparate studies of Alzheimer’s disease and related dementias (ADRD).
Worms lose their wiggle when they get Alzheimer’s disease, but UD researchers found that worms fed a diet of E. coli with higher levels of vitamin B12 were given a layer of protection from the dreaded degenerative brain disease
In a study published in the September issue of the journal Communications Biology, UNLV neuroscientists show that chronic hyperglycemia impairs working memory performance and alters fundamental aspects of working memory networks.
An inexpensive anti-seizure medication markedly improves learning and memory and other cognitive functions in Alzheimer’s patients who have epileptic activity in their brains, according to a study published in the Sept. 27th issue of JAMA Neurology.
A common treatment for Alzheimer’s disease may help people with the earliest stages of the disease maintain mitochondrial function in their muscles in addition to slowing cognitive decline. The first-of-its-kind study is published ahead of print in Function.
Empa researcher Peter Nirmalraj wants to image proteins with unprecedented precision – and thus gain insights into the molecular pathogenesis of Alzheimer's. This should pave the way for an earlier diagnosis of the dementia disorder via a simple blood test. Together with neurologists from the Kantonsspital St.Gallen, a successful pilot study has now been completed.
Dr. Melissa Hladek and Jason Resendez join the Johns Hopkins School of Nursing's On the Pulse podcast to discuss Alzheimer's disease among the Latinx population.
Recently, the National Institutes of Health (NIH) awarded researchers at the Icahn School of Medicine at Mount Sinai a five-year grant to out whether exposing patients to a combination of light therapies will slow Alzheimer’s debilitating effects.
Researchers at Rush University Medical Center have found that older adults may benefit from a specific diet called the MIND diet even when they develop these protein deposits, known as amyloid plaques and tangles.
To mark Dementia Action Week and World Alzheimer’s Day, researchers at the University of South Australia are sharing their latest insights about dementia in a new podcast series, Re-imagining Ageing.
Patients with dementia who had signs and risk factors of a pulmonary embolism, or a blood clot in the lungs, were much less likely to be tested for pulmonary embolism than patients without dementia who had the same signs and risk factors.
Using the internet during your retirement years can boost your cognitive function, a new study has found.
The University of Florida and UF Health on Tuesday, Sept. 14, announced an additional $25 million gift from the Lauren and Lee Fixel Family Foundation aimed at improving the lives of patients across the globe through the Norman Fixel Institute for Neurological Diseases at UF Health. The new investment will spur growth in the areas of national and international telemedicine, Alzheimer’s disease clinical research, mental health, traumatic brain injury and ALS and will help cultivate the next generation of expert researchers tackling these challenging diseases.
Researchers at Washington University School of Medicine in St. Louis have developed an approach to estimating when a person with no cognitive symptoms will start showing signs of Alzheimer’s dementia based on data from brain scans and the person's age.
Bristol-led research has identified specific drug targets within the neural circuits that encode memories, paving the way for significant advances in the treatment of a broad spectrum of brain disorders.
Age-related macular degeneration, cataract and diabetes-related eye disease are linked to an increased risk of dementia, suggests research published online in the British Journal of Ophthalmology.
Rutgers researchers have discovered some of the first molecular insights into how toxic proteins are regulated in neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.In a “first of its kind” study, researchers also found a potential direct connection between neurodegenerative diseases, such as Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), glaucoma, and the herpesvirus.
In a research letter in JAMA, physician-researchers at Beth Israel Deaconess Medical Center (BIDMC) found that the vast majority of patients who had a diagnosis of either cognitive impairment, Alzheimer’s disease, or Alzheimer’s disease related disorders, including cardiovascular disease, prior stroke, use of blood thinners, and age over 85 years, would have been excluded them from the aducanumab clinical trials.
A new study provides stark statistics about a reality that 6 million Americans with dementia and their families live every day: one where people with dementia receive unpaid care from spouses and adult children, and where some rely on paid help. The study finds major disparities in potential family caregiver availability, and the chance that a person with dementia will move to a nursing home.
The inaugural Mayo Clinic Conference on Brain Health and Dementia will be held virtually on Oct. 29 from 9:15 a.m. to 2:15 p.m. CDT with an optional workshop to follow. The event is a collaboration among Mayo Clinic, AARP and the Alzheimer's Association.
A new Rutgers study will examine how COVID-19 is affecting individuals in a number of cognitive-related areas, including memory loss, “brain fog,” and dementia.
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