Less invasive catheter-based aortic valve replacement and open valve-replacement surgery have a similar one-year survival for patients at high risk for surgery.
In a study that included nearly 18,000 children who had cancer, with follow-up of about 25 years, the greatest excess risk associated with a subsequent primary neoplasm (a new tumor) at older than age 40 years was for digestive and genitourinary neoplasms (related to the genital or urinary tract organs), according to a study in the June 8 issue of JAMA, a theme issue on cancer.
In a clinical trial that included nearly 80,000 women, those who received ovarian cancer screening did not have a reduced risk of death from ovarian cancer compared to women who received usual care, but did have an increase in invasive medical procedures and associated harms as a result of being screened, according to a study in the June 8 issue of JAMA, a theme issue on cancer.
An analysis of data from previously published studies indicates that longer time to beginning adjuvant chemotherapy after surgery for colorectal cancer is associated with worse survival, according to a study in the June 8 issue of JAMA, a theme issue on cancer.
Among various genetic mutations for individuals with Lynch syndrome, a hereditary cancer syndrome that carries a high risk of colon cancer and an above-normal risk of other cancers, researchers have identified mutations associated with a lower cancer risk and mutations associated with an increased risk for ovarian and endometrial cancer, according to a study in the June 8 issue of JAMA, a theme issue on cancer.
A news study finds that the worse a woman’s skin wrinkles are during the first few years of menopause, the lower her bone density is. The results will be presented Monday at The Endocrine Society’s 93rd Annual Meeting in Boston.
Estrogen therapy improves low bone density due to anorexia nervosa in teenage girls with the disease when given as a patch or as a low oral dose that is physiological (close to the form or amount of estrogen the body makes naturally). These results of a new study are being presented Monday at The Endocrine Society’s 93rd Annual Meeting in Boston.
People who have had gastric bypass surgery or other bariatric weight-loss surgery have an even higher increased risk of breaking bones than previously found. These study findings will be presented Tuesday at The Endocrine Society’s 93rd Annual Meeting in Boston.
A mutant gene long thought to accelerate tumor growth in thyroid cancer patients actually inhibits the spread of malignant cells, showing promise for novel cancer therapies, a Mayo Clinic study has found.
Men with prostate cancer are at higher risk of developing diabetes or diabetes risk factors if they receive androgen deprivation therapy (ADT) to block the production or action of male hormones that can fuel the growth of this cancer. The results of this new study on the second-most common cancer in men are being presented Saturday at The Endocrine Society’s 93rd Annual Meeting in Boston.
Women with a healthy body weight before and after diagnosis of breast cancer are more likely to survive the disease long term, a new study finds. The results will be presented Saturday at The Endocrine Society’s 93rd Annual Meeting in Boston.
Overexposure to stress hormones in the womb can program the potential for adverse health effects in those children and the next generation, but effects vary depending on whether the mother or father transmits them, a new animal study suggests. The results will be presented Saturday at The Endocrine Society’s 93rd Annual Meeting in Boston.
Low testosterone levels and symptoms of male sexual dysfunction due to obesity may be reversible with weight loss after bariatric surgery, a new study finds. The results will be presented Saturday at The Endocrine Society’s 93rd Annual Meeting in Boston.
An experimental cure for Type 1 diabetes has a nearly 80 percent success rate in curing diabetic mice. The results, to be presented Saturday at The Endocrine Society’s 93rd Annual Meeting in Boston, offer possible hope of curing a disease that affects 3 million Americans.
Daily exposure to a chemical that is prevalent in the human environment, bisphenol A (BPA), causes lowered fertility in male mice, according to the results of a new study that will be presented Saturday at The Endocrine Society’s 93rd Annual Meeting in Boston.
Formoterol, a medication used to treat asthma and other lung diseases, improves fat burning and protein metabolism in men, a new study finds. The results will be presented Saturday at The Endocrine Society’s 93rd Annual Meeting in Boston.
The drug topiramate can help people lose weight as long as they can tolerate the side effects, according to authors of a new study that reviewed the medical literature. Brazilian researchers will present the results Saturday at The Endocrine Society’s 93rd Annual Meeting in Boston.
Additional radiation treatment improves disease free survival lessening the chance of cancer recurring in women with early breast cancer who have had breast conserving surgery (lumpectomy), interim results of a new study found. Until now, the benefit of adding RNI for women with one to three positive nodes has been unclear.
Today’s announcement that the drug exemestane significantly reduces the risk of breast cancer in high-risk, postmenopausal women is the result of an international, clinical trial in which UB researchers and hundreds of area women played a role.
Researchers at Columbia University Medical Center are honing in on the development of what may be the first non-steroidal, oral contraceptive for men. Tests of low doses of a compound that interferes with retinoic acid receptors (RARs) showed that it caused sterility in male mice.
An Indiana University study that exposed older veterans with stroke to yoga produced "exciting" results as researchers explore whether this popular mind-body practice can help stroke victims cope with their increased risk for painful and even deadly falls.
An Indiana U. study found surprising differences in physical fitness levels between more affluent members of a medically affiliated fitness center and patients of a safety net community health center, which serves more vulnerable populations.
Customizing targeted therapies to each tumor’s molecular characteristics, instead of a one-size-fits-all approach by tumor type, may be more effective for some types of cancer, according to research conducted by The University of Texas MD Anderson Cancer Center.
Students overall performed better – and educationally disadvantaged students generally made even greater strides than everyone else – in an introductory biology course at a university where recent budget woes doubled class sizes for the course, cut lab times and reduced the number of graduate teaching assistants.
Whether barefoot running reduces or increases the risk of injury is a hot issue among runners. Indiana U. physical therapy expert Stuart Warden says it could do both for some runners. He discusses this at the ACSM annual meeting on Thursday.
Unwed mothers face poorer health at midlife than do women who have children after marriage, according to a new nationwide study.
Divorce is a drag on the academic and emotional development of young children, but only once the breakup is under way, according to a study of elementary school students and their families.
Children whose parents get divorced generally don’t experience detrimental setbacks in the pre-divorce period, but often fall behind their peers—and don’t catch up—when it comes to math and interpersonal social skills after their parents begin the divorce process, according to a new study.
Black and Mexican American doctors and lawyers aren’t any more likely to play “high-status” sports such as golf or tennis than less educated people within their racial-ethnic groups, and more educated blacks may actually be less inclined to do so, suggests a new study.
Unwed mothers face poorer health at midlife than do women who have children after marriage, according to a new nationwide study, which appears in the June 2011 issue of the American Sociological Review.
An advanced imaging technique has revealed that some U.S. military personnel with mild blast-related traumatic brain injuries have abnormalities in the brain that have not been seen with other types of imaging.
Two UAB researchers have found a testing method for CMV that they say is more reliable than the traditional method. CMV is the leading cause of hearing loss in babies. Their findings will be published in the June 2, 2011 New England Journal of Medicine.
First cancer vaccine to show improved response rate.
Scientists at Dana-Farber Cancer Institute have identified an overactive network of growth-spurring genes that drive stem-like breast cancer cells enriched in triple-negative breast tumors, a typically aggressive cancer that is highly resistant to current therapies.
Overweight and obese people looking to drop some pounds and considering one of the popular low-carbohydrate diets, along with moderate exercise, need not worry that the higher proportion of fat in such a program compared to a low-fat, high-carb diet may harm their arteries, suggests a pair of new studies by heart and vascular researchers at Johns Hopkins.
Johns Hopkins Children’s Center scientists have found that having a regular outpatient mental health provider may not be enough to prevent children and teens with behavioral problems from repeatedly ending up in the emergency room. The study is published in the June 1 issue of the journal Psychiatric Services.
Despite concerns that surgeon fatigue is leading to dangerous complications for patients and data showing worse outcomes for many patients who undergo surgery at night, new Johns Hopkins research suggests that — in the case of heart and lung transplants — time of day has no affect on patient survival.
An analysis of data on heart and lung transplant recipients indicates that patients who had transplant surgery performed at nighttime did not have a significantly different rate of survival up to one year after organ transplantation, according to a study in the June 1 issue of JAMA.
Use of established fracture prediction methods in older patients with type 2 diabetes mellitus (DM) found that scores from these methods were associated with hip and nonspine fracture risk, and a certain score associated with higher risk of fracture compared to persons without DM, according to a study in the June 1 issue of JAMA. Because patients with type 2 DM often have higher levels of bone mineral density (BMD), it has been uncertain the applicability of fracture risk screening methods typically used for patients with lower levels of BMD.
Frequently cited studies involving associations of biomarkers report effect sizes that are often larger when compared to summary estimates from meta-analyses evaluating the same associations, according to a study in the June 1 issue of JAMA.
Cutting back on sleep drastically reduces a healthy young man's testosterone levels, with a host of negative health effects.
Landmark study of personalized therapy may lead to a “flood of new agents.”
A promising cancer treatment drug can restore function of a heart en route to failure from high blood pressure, researchers at UT Southwestern Medical Center have found.
A DNA-based study sheds new light on the complex evolutionary history of the woolly mammoth, suggesting it mated with a completely different and much larger species. The research, which appears in the BioMed Central’s open access journal Genome Biology, found the woolly mammoth, which lived in the cold climate of the Arctic tundra, interbred with the Columbian mammoth, which preferred the more temperate regions of North America and was some 25 per cent larger.
Contrary to earlier reports, a new study finds that stress does not appear to increase a person’s risk of developing multiple sclerosis (MS). The research is published in the May 31, 2011, print issue of Neurology®, the medical journal of the American Academy of Neurology.
A new treatment that treats a subset of stroke patients by combining minimally invasive surgery, an imaging technique likened to “GPS for the brain,” and the clot-busting drug t-PA appears to be safe and effective, according to a multicenter clinical trial led by Johns Hopkins researchers.
New research published in the journal Science, led by Rensselaer Polytechnic Institute scientist Miriam Katz, is providing some of the strongest evidence to date that the Antarctic Circumpolar Current (ACC) played a key role in the major shift in the global climate that began approximately 38 million years ago. The research provides the first evidence that early ACC formation played a vital role in the formation of the modern ocean structure.
Researchers at the Kimmel Cancer Center at Jefferson show that a simple sugar, lactate, is like “candy for cancer cells.”
Seattle BioMed’s Aderem shares Insight into rational vaccine development using new approaches.
A UCLA study is the first to reveal how autism makes its mark at the molecular level, resulting in an autistic brain that differs dramatically in structure from a healthy one. The findings provide new insight into how genes and proteins go awry in autism to alter the mind.
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